Published in Genetics on December 14, 2016
Sequence logos: a new way to display consensus sequences. Nucleic Acids Res (1990) 36.74
A comprehensive catalogue of somatic mutations from a human cancer genome. Nature (2009) 24.27
Signatures of mutational processes in human cancer. Nature (2013) 21.63
PyCogent: a toolkit for making sense from sequence. Genome Biol (2007) 20.64
Molecular basis of base substitution hotspots in Escherichia coli. Nature (1978) 13.79
Mutational processes molding the genomes of 21 breast cancers. Cell (2012) 11.22
COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res (2014) 10.77
Ensembl 2015. Nucleic Acids Res (2014) 8.30
The CpG dinucleotide and human genetic disease. Hum Genet (1988) 7.86
Bayesian Markov chain Monte Carlo sequence analysis reveals varying neutral substitution patterns in mammalian evolution. Proc Natl Acad Sci U S A (2004) 7.42
Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J (2003) 7.21
Dinucleotide relative abundance extremes: a genomic signature. Trends Genet (1995) 6.32
Evidence for ecological speciation and its alternative. Science (2009) 5.56
Isochores and the evolutionary genomics of vertebrates. Gene (2000) 4.13
Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer. Gastroenterology (1997) 3.97
Comparative DNA analysis across diverse genomes. Annu Rev Genet (1998) 3.67
Deciphering signatures of mutational processes operative in human cancer. Cell Rep (2013) 3.61
Neighboring-nucleotide effects on the rates of germ-line single-base-pair substitution in human genes. Am J Hum Genet (1998) 3.12
Global dinucleotide signatures and analysis of genomic heterogeneity. Curr Opin Microbiol (1998) 3.09
Variation in the mutation rate across mammalian genomes. Nat Rev Genet (2011) 3.09
Base-stacking and base-pairing contributions into thermal stability of the DNA double helix. Nucleic Acids Res (2006) 2.78
Mechanisms underlying mutational signatures in human cancers. Nat Rev Genet (2014) 2.57
Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome. Genome Res (2002) 2.49
Male-driven evolution. Curr Opin Genet Dev (2002) 2.37
The mutation rate of the gene for haemophilia, and its segregation ratios in males and females. Ann Eugen (1947) 1.93
Genomic DNA k-mer spectra: models and modalities. Genome Biol (2009) 1.92
The rate of spontaneous mutation of a human gene. 1935. J Genet (2004) 1.70
Genome-wide patterns and properties of de novo mutations in humans. Nat Genet (2015) 1.65
Male-driven biased gene conversion governs the evolution of base composition in human alu repeats. Mol Biol Evol (2005) 1.44
Modeling the impact of DNA methylation on the evolution of BRCA1 in mammals. Mol Biol Evol (2004) 1.42
The influence of specific neighboring bases on substitution bias in noncoding regions of the plant chloroplast genome. J Mol Evol (1997) 1.30
Transcription-coupled TA and GC strand asymmetries in the human genome. FEBS Lett (2003) 1.20
How important is DNA replication for mutagenesis? Mol Biol Evol (2000) 1.13
Evidence for recent, population-specific evolution of the human mutation rate. Proc Natl Acad Sci U S A (2015) 1.00
CG methylation. Epigenomics (2012) 0.99
Spontaneous mutation in Big Blue transgenic mice: analysis of age, gender, and tissue type. Environ Mol Mutagen (1996) 0.90
An expanded sequence context model broadly explains variability in polymorphism levels across the human genome. Nat Genet (2016) 0.90
A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures. PLoS Genet (2015) 0.85
Natural DNA precursor pool asymmetry and base sequence context as determinants of replication fidelity. J Biol Chem (1995) 0.84
Exploiting CpG hypermutability to identify phenotypically significant variation within human protein-coding genes. Genome Biol Evol (2011) 0.81