Published in J Biol Chem on December 22, 2016
Quadruplex DNA: sequence, topology and structure. Nucleic Acids Res (2006) 6.42
Extracellular DNA traps promote thrombosis. Proc Natl Acad Sci U S A (2010) 5.69
Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo. Cell (2009) 4.50
A familial hemorrhagic trait associated with a deficiency of a clot-promoting fraction of plasma. J Clin Invest (1955) 4.02
Defective thrombus formation in mice lacking coagulation factor XII. J Exp Med (2005) 3.59
Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation. Proc Natl Acad Sci U S A (2007) 3.36
Polyphosphate modulates blood coagulation and fibrinolysis. Proc Natl Acad Sci U S A (2006) 3.09
International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev (2005) 2.98
Polyphosphate exerts differential effects on blood clotting, depending on polymer size. Blood (2010) 2.66
Polyphosphate is a cofactor for the activation of factor XI by thrombin. Blood (2011) 2.24
Dual role of collagen in factor XII-dependent thrombus formation. Blood (2009) 2.01
Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood (1993) 1.97
Thrombosis: tangled up in NETs. Blood (2013) 1.85
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo. Blood (2010) 1.83
Factor XII inhibition reduces thrombus formation in a primate thrombosis model. Blood (2014) 1.81
Activation of human blood coagulation factor XI independent of factor XII. Factor XI is activated by thrombin and factor XIa in the presence of negatively charged surfaces. J Biol Chem (1991) 1.81
Mechanisms for the involvement of high molecular weight kininogen in surface-dependent reactions of Hageman factor. Proc Natl Acad Sci U S A (1976) 1.59
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation. J Clin Invest (2008) 1.59
Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis. Blood (2014) 1.55
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII. Blood (2006) 1.52
Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation. Blood (2012) 1.46
The plasma kallikrein-kinin system: its evolution from contact activation. J Thromb Haemost (2007) 1.35
Neutrophil extracellular traps promote thrombin generation through platelet-dependent and platelet-independent mechanisms. Arterioscler Thromb Vasc Biol (2014) 1.22
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding. Blood (2011) 1.22
Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation. Blood (2012) 1.14
Factor XII regulates the pathological process of thrombus formation on ruptured plaques. Arterioscler Thromb Vasc Biol (2014) 1.11
Phosphoramidate end labeling of inorganic polyphosphates: facile manipulation of polyphosphate for investigating and modulating its biological activities. Biochemistry (2010) 1.08
Novel roles for factor XII-driven plasma contact activation system. Curr Opin Hematol (2008) 1.06
Kinetics of activation and autoactivation of human factor XII. Biochemistry (1984) 1.03
Role of Factor XII in hemostasis and thrombosis: clinical implications. Expert Rev Cardiovasc Ther (2007) 1.00
Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease. Atherosclerosis (2002) 0.99
Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction. Am Heart J (2004) 0.97
Autoactivation of human plasma prekallikrein. J Biol Chem (1987) 0.96
Cleavage of human high molecular weight kininogen markedly enhances its coagulant activity. Evidence that this molecule exists as a procofactor. J Clin Invest (1984) 0.96
Single-chain factor XII exhibits activity when complexed to polyphosphate. J Thromb Haemost (2014) 0.94
Autoactivatability of human Hageman factor (factor XII). Biochem Biophys Res Commun (1980) 0.93
Contact system revisited: an interface between inflammation, coagulation, and innate immunity. J Thromb Haemost (2016) 0.92
The dimeric structure of factor XI and zymogen activation. Blood (2013) 0.92
Factor XI anion-binding sites are required for productive interactions with polyphosphate. J Thromb Haemost (2013) 0.90
A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation. Thromb Res (2016) 0.86
Zinc: an important cofactor in haemostasis and thrombosis. Thromb Haemost (2013) 0.85
Structural requirements for the procoagulant activity of nucleic acids. PLoS One (2012) 0.85
Comparison of the Proinflammatory and Procoagulant Properties of Nuclear, Mitochondrial, and Bacterial DNA. Shock (2015) 0.84
Quadruplex structure of polyriboinosinic acid: dependence on alkali metal ion concentration, pH and temperature. J Phys Chem B (2008) 0.84
Surface-independent acceleration of factor XII activation by zinc ions. II. Direct binding and fluorescence studies. J Biol Chem (1993) 0.82
Studies on the temperature-dependent autoinhibition of human plasma kallikrein I. Biochem J (1982) 0.77
FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow. Blood (2015) 1.61
Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis. Blood (2014) 1.55
Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor. Blood (2016) 0.83
Polyphosphate as modulator of hemostasis, thrombosis, and inflammation. J Thromb Haemost (2015) 0.78
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA. Blood (2016) 0.75
Deeper understanding of carboxylase. Blood (2016) 0.75
Silica particles contribute to the procoagulant activity of DNA and polyphosphate isolated using commercial kits. Blood (2017) 0.75
Multiplexed silicon photonic sensor arrays enable facile characterization of coagulation protein binding to Nanodiscs with variable lipid content. J Biol Chem (2017) 0.75
Lipid Specificity of the Membrane Binding Domain of Coagulation Factor X. J Thromb Haemost (2017) 0.75
Diversification of polyphosphate end-labeling via bridging molecules. PLoS One (2020) 0.75