Published in RNA Biol on December 23, 2016
Tumor angiogenesis: therapeutic implications. N Engl J Med (1971) 35.36
Does the ribosome translate cancer? Nat Rev Cancer (2003) 6.89
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol (1999) 5.55
Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells. Biochemistry (1985) 4.50
Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol (2009) 4.07
Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA (2010) 3.40
Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell (2011) 3.23
RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. Genes Dev (2010) 2.90
Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell (2006) 2.89
Stress induces tRNA cleavage by angiogenin in mammalian cells. FEBS Lett (2008) 2.66
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem (2010) 2.61
Amino acid sequence of human tumor derived angiogenin. Biochemistry (1985) 2.56
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers. Proc Natl Acad Sci U S A (2015) 2.35
Primary processing of mammalian rRNA involves two adjacent cleavages and is not species specific. Mol Cell Biol (1987) 2.28
Characteristic ribonucleolytic activity of human angiogenin. Biochemistry (1986) 2.06
Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity. Proc Natl Acad Sci U S A (1994) 1.99
Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis. Biochemistry (1989) 1.91
Identification and characterization of an angiogenin-binding DNA sequence that stimulates luciferase reporter gene expression. Biochemistry (2003) 1.78
Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro. J Biol Chem (1995) 1.75
RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis. Nat Struct Mol Biol (2012) 1.75
Slicing tRNAs to boost functional ncRNA diversity. RNA Biol (2013) 1.68
Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. Nucleic Acids Res (2012) 1.66
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor. Mol Endocrinol (1996) 1.61
Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly. Mol Cell (2007) 1.59
FLASH is required for histone transcription and S-phase progression. Proc Natl Acad Sci U S A (2006) 1.56
Human placental ribonuclease inhibitor abolishes both angiogenic and ribonucleolytic activities of angiogenin. Proc Natl Acad Sci U S A (1987) 1.55
FLASH, a proapoptotic protein involved in activation of caspase-8, is essential for 3' end processing of histone pre-mRNAs. Mol Cell (2009) 1.49
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. J Biol Chem (2012) 1.47
Identification and functional characterization of tRNA-derived RNA fragments (tRFs) in respiratory syncytial virus infection. Mol Ther (2012) 1.41
Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response. PLoS One (2010) 1.41
tRNA fragments in human health and disease. FEBS Lett (2014) 1.41
Mechanisms of action of angiogenin. Acta Biochim Biophys Sin (Shanghai) (2008) 1.38
A putative angiogenin receptor in angiogenin-responsive human endothelial cells. Proc Natl Acad Sci U S A (1997) 1.38
Mapping the cleavage sites on mammalian pre-rRNAs: where do we stand? Biochimie (2012) 1.37
Apoptosome structure, assembly, and procaspase activation. Structure (2013) 1.33
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J (2014) 1.31
An overview of pre-ribosomal RNA processing in eukaryotes. Wiley Interdiscip Rev RNA (2014) 1.30
RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing. Proc Natl Acad Sci U S A (2006) 1.28
Base cleavage specificity of angiogenin with Saccharomyces cerevisiae and Escherichia coli 5S RNAs. Biochemistry (1988) 1.26
The nuclear function of angiogenin in endothelial cells is related to rRNA production. Biochem Biophys Res Commun (2002) 1.23
Efficient and quantitative high-throughput tRNA sequencing. Nat Methods (2015) 1.21
Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress. Mol Cell Biol (2014) 1.18
Angiogenin is a cytotoxic, tRNA-specific ribonuclease in the RNase A superfamily. J Biol Chem (1992) 1.18
Stress granules, P-bodies and cancer. Biochim Biophys Acta (2014) 1.17
Identification of the nucleolar targeting signal of human angiogenin. Biochem Biophys Res Commun (1994) 1.17
Role of glutamine-117 in the ribonucleolytic activity of human angiogenin. Proc Natl Acad Sci U S A (1994) 1.17
ARM-seq: AlkB-facilitated RNA methylation sequencing reveals a complex landscape of modified tRNA fragments. Nat Methods (2015) 1.17
A covalent angiogenin/ribonuclease hybrid with a fourth disulfide bond generated by regional mutagenesis. Biochemistry (1989) 1.16
Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis. Biochemistry (1993) 1.14
Angiogenin is regulated in vivo as an acute phase protein. Biochem Biophys Res Commun (1998) 1.09
Angiogenin-stimulated rRNA transcription is essential for initiation and survival of AKT-induced prostate intraepithelial neoplasia. Mol Cancer Res (2009) 1.08
Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C. Sci Rep (2015) 1.05
Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress. PLoS Genet (2013) 1.05
The eight human "canonical" ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins. FEBS Lett (2010) 1.03
Transcription in cloned spacers of Xenopus laevis ribosomal DNA. Proc Natl Acad Sci U S A (1983) 1.03
The widespread expression of angiogenin in different human cells suggests a biological function not only related to angiogenesis. Eur J Biochem (1994) 1.02
Motoneurons secrete angiogenin to induce RNA cleavage in astroglia. J Neurosci (2012) 0.97
Neamine inhibits prostate cancer growth by suppressing angiogenin-mediated rRNA transcription. Clin Cancer Res (2009) 0.96
Dynamic RNA modifications in posttranscriptional regulation. Mol Cell (2014) 0.95
Basic mechanisms in RNA polymerase I transcription of the ribosomal RNA genes. Subcell Biochem (2013) 0.94
Mechanistic insights into mammalian stress granule dynamics. J Cell Biol (2016) 0.91
Respiratory Syncytial Virus Utilizes a tRNA Fragment to Suppress Antiviral Responses Through a Novel Targeting Mechanism. Mol Ther (2015) 0.91
Hypoxia-induced up-regulation of angiogenin, besides VEGF, is related to progression of oral cancer. Oral Oncol (2012) 0.88
Stem cell function and stress response are controlled by protein synthesis. Nature (2016) 0.87
Binding of placental ribonuclease inhibitor to the active site of angiogenin. Biochemistry (1989) 0.87
Angiogenin mediates androgen-stimulated prostate cancer growth and enables castration resistance. Mol Cancer Res (2013) 0.85
The expansion and functional diversification of the mammalian ribonuclease a superfamily epitomizes the efficiency of multigene families at generating biological novelty. Genome Biol Evol (2013) 0.85
Dynamic RNA modifications in disease. Curr Opin Genet Dev (2014) 0.84
Angiogenin stimulates ribosomal RNA transcription by epigenetic activation of the ribosomal DNA promoter. J Cell Physiol (2014) 0.82
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res (2016) 0.78
Molecular basis for the autonomous promotion of cell proliferation by angiogenin. Nucleic Acids Res (2016) 0.78