Published in Ann N Y Acad Sci on March 04, 1977
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Proc Natl Acad Sci U S A (1977) 11.20
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate. J Virol (1979) 4.53
Acyclovir inhibition of Epstein-Barr virus replication. Proc Natl Acad Sci U S A (1980) 2.23
Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell culture. Antimicrob Agents Chemother (1987) 2.11
Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities. J Virol (1981) 1.74
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U. Antimicrob Agents Chemother (1984) 1.67
Effect of combinations of acyclovir with vidarabine or its 5'-monophosphate on herpes simplex viruses in cell culture and in mice. Antimicrob Agents Chemother (1982) 1.48
Phosphorylation of acyclovir [9-(2-hydroxyethoxymethyl)guanine] in Epstein-Barr virus-infected lymphoblastoid cell lines. J Virol (1981) 1.44
Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir. Antimicrob Agents Chemother (1980) 1.41
2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir. Proc Natl Acad Sci U S A (1989) 1.26
Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates. Antimicrob Agents Chemother (1985) 1.17
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition. Proc Natl Acad Sci U S A (1985) 1.08
Flow cytometric analysis of herpes simplex virus type 1 susceptibility to acyclovir, ganciclovir, and foscarnet. Antimicrob Agents Chemother (1997) 1.01
Activity of trifluorothymidine against cytomegalovirus. Antimicrob Agents Chemother (1981) 0.94
Activities of two new antiviral agents against guinea pig lymphotropic herpesvirus infection in vitro. Antimicrob Agents Chemother (1989) 0.75
The stereoselective enzymatic synthesis of 9-beta-D-2'-deoxyribofuranosyl 1-deazapurine. Nucleic Acids Res (1989) 0.75
9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group. Nature (1978) 9.21
Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet (1993) 3.56
Cardiac syndrome X: clinical characteristics and left ventricular function. Long-term follow-up study. J Am Coll Cardiol (1995) 2.89
Hormone replacement therapy and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation (2001) 2.80
Vagal reflexes appearing in asphyxia in rabbits at different ages. J Physiol (1939) 2.58
Estrogen hits the surface. Nat Med (1999) 2.24
Hypothesis: inhibition of endothelium-derived relaxing factor by haemoglobin in the pathogenesis of pre-eclampsia. Lancet (1990) 2.24
Importance of carbon dioxide in the isolation of pneumococci. J Bacteriol (1966) 2.21
The photosensitivity dermatitis and actinic reticuloid syndrome (chronic actinic dermatitis) occurring in seven young atopic dermatitis patients. Br J Dermatol (1998) 2.10
Impaired glucose tolerance in first-episode drug-naïve patients with schizophrenia. Diabet Med (2007) 2.06
The effect of asphyxia upon the heart rate of rabbits at different ages. J Physiol (1938) 2.02
Mood, personality, and self-monitoring: negative affect and emotionality in relation to frontal lobe mechanisms of error monitoring. J Exp Psychol Gen (2000) 2.01
Survey of resistance of herpes simplex virus to acyclovir in northwest England. Antimicrob Agents Chemother (1998) 1.89
The dependence of some strains of Mycobacterium avium on mycobactin for initial and subsequent growth. J Med Microbiol (1978) 1.86
The activity in vitro against herpes virus of 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine), a new antiviral agent. J Antimicrob Chemother (1979) 1.85
Therapeutic potentiation of the immune system by costimulatory Schiff-base-forming drugs. Nature (1995) 1.85
Differential effects of 6-OHDA lesions of the frontal cortex and caudate nucleus on the ability to acquire an attentional set. Cereb Cortex (2001) 1.83
Blood transfusion and the anaesthetist: management of massive haemorrhage. Anaesthesia (2010) 1.77
A survey of the intended management of acute postoperative pain by newly qualified doctors in the south west region of England in August 1992. Anaesthesia (1994) 1.74
Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). J Thromb Haemost (2012) 1.74
The pathogenicity of Mycobacterium avium and related mycobacteria for experimental animals. J Med Microbiol (1983) 1.72
6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine. J Neurosci (1994) 1.70
4',6-Dichloroflavan (BW683C), a new anti-rhinovirus compound. Nature (1981) 1.69
The reproductive effects of beta interferon therapy in pregnancy: a longitudinal cohort. Neurology (2005) 1.62
Hormone replacement therapy and the cardiovascular system. Nonlipid effects. Drugs (1994) 1.61
Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease. Circulation (1999) 1.58
The roles of gender, the menopause and hormone replacement on cardiovascular function. Cardiovasc Res (2000) 1.55
Strong constraints on the rare decays B(s)(0) → μ+ μ- and B0 → μ+ μ-. Phys Rev Lett (2012) 1.50
Plant-derived estrogens relax coronary arteries in vitro by a calcium antagonistic mechanism. J Am Coll Cardiol (2000) 1.50
First observation of the decays B(0) → D(+)K(-)π(+)π(-) and B(-) → D(0)K(-)π(+)π(-). Phys Rev Lett (2012) 1.50
Clinical experience with the antiviral drug marboran (1-methylisatin 3-thiosemicarbazone). Ann N Y Acad Sci (1965) 1.49
Chronic lymphocytic leukemic (CLL) cells secrete multispecific autoantibodies. J Autoimmun (1988) 1.49
Failure to demonstrate myocardial ischaemia in patients with angina and normal coronary arteries. Evaluation by continuous coronary sinus pH monitoring and lactate metabolism. Eur Heart J (1996) 1.46
Prophylaxis of smallpox with methisazone. Am J Epidemiol (1969) 1.46
Esterified estrogens combined with methyltestosterone improve emotional well-being in postmenopausal women with chest pain and normal coronary angiograms. Menopause (2001) 1.45
Improvement in angina pectoris with alpha adrenoceptor blockade. Br Heart J (1985) 1.44
Successful treatment of experimental B virus (Herpesvirus simiae) infection with acyclovir. Br Med J (1980) 1.44
Effects of storage solutions on in vitro vasoreactivity of radial artery conduits. J Thorac Cardiovasc Surg (2001) 1.43
Nonmelanoma skin cancer in an Irish population: an appraisal of risk factors. Ir Med J (1995) 1.43
The effects of cardiopulmonary bypass on systemic and coronary levels of von Willebrand factor. Eur J Cardiothorac Surg (1995) 1.43
Testosterone relaxes rabbit coronary arteries and aorta. Circulation (1995) 1.42
Determination of the X(3872) meson quantum numbers. Phys Rev Lett (2013) 1.42
Clinical and genetic predictors of response to narrowband ultraviolet B for the treatment of chronic plaque psoriasis. Br J Dermatol (2010) 1.42
Symptoms of post-traumatic stress disorder in 11 police officers. Can J Psychiatry (1995) 1.42
Transcription of full-length and truncated mRNA transcripts to study protein translocation across the endoplasmic reticulum. Methods Cell Biol (1991) 1.40
Hormone replacement therapy and heart-rate variability. Lancet (1999) 1.40
Comparison of activity of herpes virus inhibitors. J Antimicrob Chemother (1977) 1.40
Oral vaccination of calves against experimental salmonellosis using a double aro mutant of Salmonella typhimurium. Vaccine (1991) 1.40
Apolipoprotein (a) and ischaemic heart disease. Lancet (1990) 1.39
Bayesian analysis of pentaquark signals from CLAS data. Phys Rev Lett (2008) 1.39
Antiviral chemotherapy. Mod Trends Med Virol (1967) 1.39
Treatment of experimental herpes simplex keratitis with acycloguanosine. Br J Ophthalmol (1979) 1.36
Access of proteinase K to partially translocated nascent polypeptides in intact and detergent-solubilized membranes. J Cell Biol (1989) 1.35
Endothelium-independent relaxation of rabbit coronary artery by 17 beta-oestradiol in vitro. Br J Pharmacol (1991) 1.35
Helicopter transport of patients during acute myocardial infarction. Am J Cardiol (1988) 1.32
Testosterone induces dilation of canine coronary conductance and resistance arteries in vivo. Circulation (1996) 1.30
Tuberculosis in wild seals and characterisation of the seal bacillus. Aust Vet J (1993) 1.29
Biological activities of some purine arabinosides. Ann N Y Acad Sci (1975) 1.25
Increased gene expression of brown fat uncoupling protein (UCP)1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia. Cancer Res (2000) 1.23
Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. J Clin Invest (1997) 1.22
Effect of 17 beta-oestradiol on contraction, Ca2+ current and intracellular free Ca2+ in guinea-pig isolated cardiac myocytes. Br J Pharmacol (1992) 1.22
First observation of CP violation in the decays of B(s)0 mesons. Phys Rev Lett (2013) 1.21
Australia antigen in urine. Lancet (1971) 1.18
Adenovirus multiplication: inhibition by methisazone. Science (1966) 1.18
Dopamine and the structure of personality: relation of agonist-induced dopamine activity to positive emotionality. J Pers Soc Psychol (1994) 1.18
Effect of acute testosterone on myocardial ischemia in men with coronary artery disease. Am J Cardiol (1999) 1.17
Cardiac tamponade in acute pancreatitis. Thorax (1980) 1.17
Acyclovir-resistant herpes in AIDS treated with foscarnet. Lancet (1988) 1.14
Readability of self-care instructional pamphlets for diabetic patients. Diabetes Care (1982) 1.11
Psychoactive drugs in mania. A controlled comparison of lithium carbonate, chlorpromazine, and haloperidol. Arch Gen Psychiatry (1975) 1.11
Design and methods of the Raloxifene Use for The Heart (RUTH) study. Am J Cardiol (2001) 1.10
Effect of exercise on cerebral perfusion in humans at high altitude. J Appl Physiol (1985) (2005) 1.09
Mechanisms of estrogen-induced vasodilation: in vivo studies in canine coronary conductance and resistance arteries. J Am Coll Cardiol (1995) 1.08
Endothelium-derived relaxing factor alters calcium fluxes in rabbit aorta: a cyclic guanosine monophosphate-mediated effect. J Physiol (1986) 1.08
Hyperinsulinaemia is associated with stimulation of cholesterol synthesis in both type 1 and type 2 diabetes. Diabet Med (1993) 1.08
Elevated peripheral neutrophils and matrix metalloproteinase 9 as biomarkers of functional outcome following subarachnoid hemorrhage. Transl Stroke Res (2011) 1.08
Pregnancy-associated acquired haemophilia A: results from the European Acquired Haemophilia (EACH2) registry. BJOG (2012) 1.08
Response to triiodothyronine and dextroamphetamine: a study of preschool schizophrenic children. J Autism Child Schizophr (1973) 1.07
Estrogen acutely increases peripheral blood flow in postmenopausal women. Am J Med (1995) 1.07
Comparative value of four methods of investigating the pancreas. Surgery (1976) 1.07
Expression of uncoupling proteins-1, -2 and -3 mRNA is induced by an adenocarcinoma-derived lipid-mobilizing factor. Br J Cancer (2002) 1.06
The regulation of post-prandial cellular cholesterol metabolism in type 2 diabetic and non-diabetic subjects. Diabet Med (1993) 1.06
Cyclical variation in paroxysmal supraventricular tachycardia in women. Lancet (1996) 1.06
New technique for servo-control of arterial oxygen tension in preterm infants. Arch Dis Child (1979) 1.05
Acyclovir-resistant herpes simplex virus infection due to altered DNA polymerase. Lancet (1987) 1.04
The antibody repertoire of early human B cells. I. High frequency of autoreactivity and polyreactivity. Scand J Immunol (1990) 1.04
The impact of HIV disease progression on serum lipoproteins. AIDS (1992) 1.03
Differences in basal endothelium-derived relaxing factor activity in different artery types. J Cardiovasc Pharmacol (1987) 1.02
Agonist-induced production of 1,2-diacylglycerol and phosphatidic acid in intact resistance arteries. Evidence that accumulation of diacylglycerol is not a prerequisite for contraction. J Biol Chem (1990) 1.01
The relative potencies of anti-influenza compounds. Ann N Y Acad Sci (1977) 1.01
Oestrogen relaxes human epicardial coronary arteries through non-endothelium-dependent mechanisms. Coron Artery Dis (1995) 1.00
Acute effect of 17 beta-estradiol on rabbit coronary artery contractile responses to endothelin-1. Am J Physiol (1992) 1.00
The ventricular surface of the subcommissural organ: a scanning and transmission electron microscopic study. J Anat (1979) 1.00
The spectrum of antiviral activities of acyclovir in vitro and in vivo. J Antimicrob Chemother (1983) 1.00