Published in Phys Rev Lett on April 18, 2012
Performance of the LHCb RICH detector at the LHC. Eur Phys J C Part Fields (2013) 2.43
Experimental constraints from flavour changing processes and physics beyond the Standard Model. Eur Phys J C Part Fields (2012) 0.75
The sequence of the human genome. Science (2001) 101.55
Trends, rhythms, and aberrations in global climate 65 Ma to present. Science (2001) 27.08
The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators. JAMA (1996) 17.62
High sensitivity mapping of methylated cytosines. Nucleic Acids Res (1994) 16.62
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nat Biotechnol (2000) 15.79
Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2. Methods Enzymol (1979) 13.61
Comparative genomics of Listeria species. Science (2001) 12.94
A Simple Method for the Silver Impregnation of Reticulum. Am J Pathol (1936) 9.76
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum (1987) 9.24
Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood (2000) 9.24
9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group. Nature (1978) 9.21
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. JAMA (2001) 8.40
The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. JAMA (1997) 8.30
Explaining differences in English hospital death rates using routinely collected data. BMJ (1999) 8.27
The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum (1995) 7.97
Standardisation of the measurement of lung volumes. Eur Respir J (2005) 7.48
The DNA sequence and comparative analysis of human chromosome 20. Nature (2002) 7.40
"White-opaque transition": a second high-frequency switching system in Candida albicans. J Bacteriol (1987) 7.33
Medical student selection: a tentative attempt to establish a code of practice. Br Med J (1980) 7.21
Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med (1996) 6.79
Ordered rearrangement of immunoglobulin heavy chain variable region segments. EMBO J (1984) 6.67
Prevalence of specific language impairment in kindergarten children. J Speech Lang Hear Res (1997) 6.37
Population genetic structure of variable drug response. Nat Genet (2001) 6.35
The Neutron Pile as a Tool in Quantitative Analysis; The Gallium and Palladium Content of Iron Meteorites. Science (1949) 6.35
Zymohexase: With an Addendum by E. C. Bate-Smith. Biochem J (1940) 6.34
Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. N Engl J Med (1991) 6.33
Organization and reorganization of immunoglobulin genes in A-MULV-transformed cells: rearrangement of heavy but not light chain genes. Cell (1981) 6.31
Auditing audits: the method of Oxfordshire Medical Audit Advisory Group. BMJ (1991) 6.22
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med (1999) 6.09
Herpes simplex virus turns off the TAP to evade host immunity. Nature (1995) 5.93
Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis. Mol Cell Biol (1987) 5.93
Automated DNA sequencing of the human HPRT locus. Genomics (1990) 5.92
Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol (2001) 5.87
Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments) Am J Respir Crit Care Med (1996) 5.82
Gender differences in depression. Critical review. Br J Psychiatry (2000) 5.71
Biodegradation: problems of molecular recalcitrance and microbial fallibility. Adv Appl Microbiol (1965) 5.67
Climate impact of increasing atmospheric carbon dioxide. Science (1981) 5.67
beta Blockade after myocardial infarction: systematic review and meta regression analysis. BMJ (1999) 5.66
A receptor in pituitary and hypothalamus that functions in growth hormone release. Science (1996) 5.45
Breast tumor cell lines from pleural effusions. J Natl Cancer Inst (1974) 5.39
Nomenclature and classification of purinoceptors. Pharmacol Rev (1994) 5.32
Holins: the protein clocks of bacteriophage infections. Annu Rev Microbiol (2000) 5.30
Outcome of low back pain in general practice: a prospective study. BMJ (1998) 5.27
Comparison of UK paediatric cardiac surgical performance by analysis of routinely collected data 1984-96: was Bristol an outlier? Lancet (2001) 5.26
An integrated computational pipeline and database to support whole-genome sequence annotation. Genome Biol (2002) 5.24
Do cells cycle? Proc Natl Acad Sci U S A (1973) 5.20
Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. J Virol (1992) 5.18
Localization of neuronal and glial glutamate transporters. Neuron (1994) 5.14
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03
Measuring the extent and effectiveness of protected areas as an indicator for meeting global biodiversity targets. Philos Trans R Soc Lond B Biol Sci (2005) 4.94
Increased bone formation in osteocalcin-deficient mice. Nature (1996) 4.91
Twenty five years of case finding and audit in a socially deprived community. BMJ (1991) 4.89
Iatrogenic illness on a general medical service at a university hospital. N Engl J Med (1981) 4.82
Searching MEDLINE for randomized clinical trials involving care of the newborn. Pediatrics (1989) 4.79
The complex of myxomas, spotty pigmentation, and endocrine overactivity. Medicine (Baltimore) (1985) 4.64
Circulating nucleic acids (CNAs) and cancer--a survey. Biochim Biophys Acta (2006) 4.60
The effects of recall on estimating annual nonfatal injury rates for children and adolescents. Am J Public Health (1994) 4.60
A Critical Study of the Methods of Estimating Cholesterol and Allied Substances. Biochem J (1921) 4.58
Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell (1999) 4.57
Small-bowel changes in dermatitis herpetiformis. Lancet (1966) 4.49
Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1989) 4.45
Randomised trial of oral and intravenous methylprednisolone in acute relapses of multiple sclerosis. Lancet (1997) 4.43
A comparison of survival, growth, and pulmonary function in patients with cystic fibrosis in Boston and Toronto. J Clin Epidemiol (1988) 4.41
Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J (2001) 4.40
Lymphocyte trafficking and regional immunity. Adv Immunol (1999) 4.21
[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain. J Pharmacol Exp Ther (1989) 4.18
Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells. Nature (1984) 4.18
Distribution of NHS funds between fundholding and non-fundholding practices. BMJ (1994) 4.05
Case-control study of sudden infant death syndrome in Scotland, 1992-5. BMJ (1997) 4.03
Effect of counselling on the psychiatric morbidity associated with mastectomy. Br Med J (1980) 4.03
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci U S A (2000) 3.95
Open peer review: a randomised controlled trial. Br J Psychiatry (2000) 3.93
The relative role of "A" level chemistry, physics and biology in the medical course. Med Educ (1977) 3.89
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation. Nat Neurosci (2001) 3.85
Expression and structure of the human NGF receptor. Cell (1986) 3.82
Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature (2000) 3.78
Recognising clinical instability in hospital patients before cardiac arrest or unplanned admission to intensive care. A pilot study in a tertiary-care hospital. Med J Aust (1999) 3.76
The stroke impact scale version 2.0. Evaluation of reliability, validity, and sensitivity to change. Stroke (1999) 3.76
Residential care for elderly people: a decade of change. BMJ (1993) 3.71
Detection and identification of bacteria by gas chromatography. Appl Microbiol (1966) 3.70
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem (2001) 3.69
Distinct physiological states of Plasmodium falciparum in malaria-infected patients. Nature (2007) 3.69
Auditing audits: use and development of the Oxfordshire Medical Audit Advisory Group rating system. BMJ (1994) 3.64
Clinical spectrum of X-linked hyper-IgM syndrome. J Pediatr (1997) 3.63
Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet (1993) 3.56
Protozoa as agents responsible for the decline of Xanthomonas campestris in soil. Appl Microbiol (1975) 3.52
Complete DNA sequence of yeast chromosome XI. Nature (1994) 3.51
The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli. J Immunol (1975) 3.50
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev (1990) 3.50
Insertional mutagenesis of genes required for seed development in Arabidopsis thaliana. Genetics (2001) 3.49
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci U S A (2000) 3.44
Aerobic cometabolism of DDT analogues by Hydrogenomonas sp. J Agric Food Chem (1971) 3.43
Enrichment of gene-coding sequences in maize by genome filtration. Science (2003) 3.41
Preserving renal function in adults with hypertension and diabetes: a consensus approach. National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. Am J Kidney Dis (2000) 3.37
Bone-marrow transplantation (first of two parts). N Engl J Med (1975) 3.33