Non-Canonical and Sexually Dimorphic X Dosage Compensation States in the Mouse and Human Germline.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28132849)

Published in Dev Cell on January 26, 2017

Authors

Mahesh N Sangrithi1, Helene Royo2, Shantha K Mahadevaiah3, Obah Ojarikre3, Leena Bhaw3, Abdul Sesay3, Antoine H F M Peters4, Michael Stadler2, James M A Turner5

Author Affiliations

1: Mill Hill Laboratory, The Francis Crick Institute, The Ridgeway, Mill Hill, London NW7 1AA, UK; UCL EGA Institute for Women's Health UCL, Medical School Building, 74 Huntley Street, London WC1E 6AU, UK.
2: Friedrich Miescher Institute for Biomedical Research (FMI), 4058 Basel, Switzerland; Swiss Institute of Bioinformatics, 4058 Basel, Switzerland.
3: Mill Hill Laboratory, The Francis Crick Institute, The Ridgeway, Mill Hill, London NW7 1AA, UK.
4: Friedrich Miescher Institute for Biomedical Research (FMI), 4058 Basel, Switzerland.
5: Mill Hill Laboratory, The Francis Crick Institute, The Ridgeway, Mill Hill, London NW7 1AA, UK. Electronic address: james.turner@crick.ac.uk.

Articles cited by this

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat Protoc (2012) 35.75

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol (2013) 32.42

A global double-fluorescent Cre reporter mouse. Genesis (2007) 17.86

Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat Biotechnol (2012) 14.01

An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data. PLoS Comput Biol (2009) 7.47

Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell (2011) 6.22

An abundance of X-linked genes expressed in spermatogonia. Nat Genet (2001) 5.87

The degeneration of Y chromosomes. Philos Trans R Soc Lond B Biol Sci (2000) 5.22

The mouse X chromosome is enriched for sex-biased genes not subject to selection by meiotic sex chromosome inactivation. Nat Genet (2004) 4.62

The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell (2012) 4.32

Dosage compensation of the active X chromosome in mammals. Nat Genet (2005) 4.31

Silencing of unsynapsed meiotic chromosomes in the mouse. Nat Genet (2004) 4.25

The evolution of chromosomal sex determination and dosage compensation. Curr Biol (1996) 4.10

Meiotic sex chromosome inactivation. Development (2007) 4.03

Extensive gene traffic on the mammalian X chromosome. Science (2004) 3.89

Global analysis of X-chromosome dosage compensation. J Biol (2006) 3.78

Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice. Dev Growth Differ (1999) 3.56

Full-length RNA-seq from single cells using Smart-seq2. Nat Protoc (2014) 3.39

Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice. Science (2012) 3.03

The mouse X chromosome is enriched for multicopy testis genes showing postmeiotic expression. Nat Genet (2008) 2.95

RNA-based gene duplication: mechanistic and evolutionary insights. Nat Rev Genet (2009) 2.91

Drosophila dosage compensation: a complex voyage to the X chromosome. Development (2009) 2.87

Dosage compensation: the beginning and end of generalization. Nat Rev Genet (2007) 2.84

RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet (2010) 2.71

Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription. Nat Rev Genet (2012) 2.29

Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis. Mol Cell Biol (2005) 2.22

Y-chromosome evolution: emerging insights into processes of Y-chromosome degeneration. Nat Rev Genet (2013) 2.08

Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster. Nat Genet (2011) 2.07

Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes. PLoS Biol (2007) 2.06

Origins and functional evolution of Y chromosomes across mammals. Nature (2014) 1.89

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development. Cell (2015) 1.86

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice. Genesis (2008) 1.83

Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities. Hum Mol Genet (1998) 1.69

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells. Cell (2015) 1.66

X chromosome reactivation initiates in nascent primordial germ cells in mice. PLoS Genet (2007) 1.63

An X-to-autosome retrogene is required for spermatogenesis in mice. Nat Genet (2004) 1.63

Mammalian X upregulation is associated with enhanced transcription initiation, RNA half-life, and MOF-mediated H4K16 acetylation. Dev Cell (2013) 1.61

Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome. Proc Natl Acad Sci U S A (2012) 1.55

Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice. J Reprod Fertil (1991) 1.53

X chromosomes, retrogenes and their role in male reproduction. Trends Endocrinol Metab (2004) 1.52

Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals. PLoS Genet (2015) 1.49

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis. Hum Mol Genet (2002) 1.46

Mechanisms and evolutionary patterns of mammalian and avian dosage compensation. PLoS Biol (2012) 1.43

X chromosome activity in mouse XX primordial germ cells. PLoS Genet (2008) 1.38

X chromosome regulation: diverse patterns in development, tissues and disease. Nat Rev Genet (2014) 1.36

Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. Biol Reprod (2009) 1.34

DNA Demethylation Dynamics in the Human Prenatal Germline. Cell (2015) 1.34

DNA double strand break repair, chromosome synapsis and transcriptional silencing in meiosis. Epigenetics (2010) 1.30

The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b. Proc Natl Acad Sci U S A (2004) 1.28

Evidence of evolutionary up-regulation of the single active X chromosome in mammals based on Clc4 expression levels in Mus spretus and Mus musculus. Proc Natl Acad Sci U S A (1997) 1.28

Noncoding RNAs and epigenetic mechanisms during X-chromosome inactivation. Annu Rev Cell Dev Biol (2014) 1.25

X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription. Nat Struct Mol Biol (2011) 1.24

Relative overexpression of X-linked genes in mouse embryonic stem cells is consistent with Ohno's hypothesis. Nat Genet (2011) 1.22

Germ cell specification in mice. Curr Opin Genet Dev (2009) 1.18

Germ cell development in the XXY mouse: evidence that X chromosome reactivation is independent of sexual differentiation. Dev Biol (1999) 1.16

Independent specialization of the human and mouse X chromosomes for the male germ line. Nat Genet (2013) 1.15

Meiosis and sex chromosome aneuploidy: how meiotic errors cause aneuploidy; how aneuploidy causes meiotic errors. Curr Opin Genet Dev (2006) 1.11

Perinatal oocyte loss in XO mice and its implications for the aetiology of gonadal dysgenesis in XO women. J Reprod Fertil (1985) 1.09

X-chromosome activity in female mouse embryos heterozygous for Pgk-1 and Searle's translocation, T(X; 16) 16H. Genet Res (1983) 1.08

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells. PLoS One (2007) 1.08

Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways. Cell Mol Life Sci (2012) 1.06

Using RNA FISH to study gene expression during mammalian meiosis. Methods Mol Biol (2009) 1.04

Different flavors of X-chromosome inactivation in mammals. Curr Opin Cell Biol (2013) 1.02

Primordial germ-cell development and epigenetic reprogramming in mammals. Curr Top Dev Biol (2013) 1.02

X for intersection: retrotransposition both on and off the X chromosome is more frequent. Trends Genet (2005) 0.98

Evidence that the nonsense-mediated mRNA decay pathway participates in X chromosome dosage compensation in mammals. Biochem Biophys Res Commun (2009) 0.98

Sex chromosome inactivation in the male. Epigenetics (2009) 0.97

Retarded development of XO conceptuses during early pregnancy in the mouse. J Reprod Fertil (1983) 0.96

The Biology and Evolution of Mammalian Y Chromosomes. Annu Rev Genet (2015) 0.92

What a difference an X or Y makes: sex chromosomes, gene dose, and epigenetics in sexual differentiation. Handb Exp Pharmacol (2012) 0.92

The mammalian Y chromosome: a new perspective. Bioessays (1998) 0.91

Oocyte depletion in XO mice and their XX sibs from 12 to 200 days post partum. J Reprod Fertil (1981) 0.91

XO monosomy is associated with reduced birthweight and lowered weight gain in the mouse. J Reprod Fertil (1983) 0.87

Germ cell loss in the XXY male mouse: altered X-chromosome dosage affects prenatal development. Mol Reprod Dev (1998) 0.86

The evolution of X chromosome inactivation in mammals: the demise of Ohno's hypothesis? Cell Mol Life Sci (2013) 0.84

Mammalian meiotic silencing exhibits sexually dimorphic features. Chromosoma (2015) 0.82

Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development. BMC Genomics (2015) 0.82

Claims and counterclaims of X-chromosome compensation. Nat Struct Mol Biol (2012) 0.81

Imbalance between the expression dosages of X-chromosome and autosomal genes in mammalian oocytes. Sci Rep (2015) 0.81

[Kinetics of prespermatogenesis and spermatogenesis]. Verh Anat Ges (1974) 0.80

A FACTOR FOR THE FOURTH CHROMOSOME OF DROSOPHILA. Science (1914) 0.79

Increased expression of X-linked genes in mammals is associated with a higher stability of transcripts and an increased ribosome density. Genome Biol Evol (2015) 0.79

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification. Dev Cell (2016) 0.76