Published in Epigenetics on October 25, 2009
MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells. Genes Dev (2011) 1.52
X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells. Hum Genet (2011) 1.14
RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids. Genes Dev (2012) 1.13
Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways. Cell Mol Life Sci (2012) 1.06
ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing. Genes Dev (2013) 1.01
Expression profiling reveals developmentally regulated lncRNA repertoire in the mouse male germline. Biol Reprod (2013) 0.94
Meiotic sex chromosome inactivation is disrupted in sterile hybrid male house mice. Genetics (2013) 0.93
Error-prone ZW pairing and no evidence for meiotic sex chromosome inactivation in the chicken germ line. PLoS Genet (2012) 0.91
The τCstF-64 polyadenylation protein controls genome expression in testis. PLoS One (2012) 0.90
Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. PLoS Genet (2013) 0.90
Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation. PLoS Genet (2015) 0.85
Failure of homologous synapsis and sex-specific reproduction problems. Front Genet (2012) 0.81
Localization and regulation of murine Esco2 during male and female meiosis. Biol Reprod (2012) 0.80
Identification of germ cell-specific genes in mammalian meiotic prophase. BMC Bioinformatics (2013) 0.80
Differential expression of non-coding RNAs and continuous evolution of the X chromosome in testicular transcriptome of two mouse species. PLoS One (2011) 0.79
Escape of X-linked miRNA genes from meiotic sex chromosome inactivation. Development (2015) 0.76
Non-Canonical and Sexually Dimorphic X Dosage Compensation States in the Mouse and Human Germline. Dev Cell (2017) 0.75
TauCstF-64 Mediates Correct mRNA Polyadenylation and Splicing of Activator and Repressor Isoforms of the Cyclic AMP-Responsive Element Modulator (CREM) in Mouse Testis. Biol Reprod (2015) 0.75
The functions of animal microRNAs. Nature (2004) 64.85
Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature (1961) 23.98
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell (2004) 16.10
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature (2005) 13.44
X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature (2005) 12.06
Role of histone H3 lysine 27 methylation in X inactivation. Science (2003) 9.85
Requirement for Xist in X chromosome inactivation. Nature (1996) 8.24
Xist RNA and the mechanism of X chromosome inactivation. Annu Rev Genet (2002) 8.06
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell (1992) 8.05
Genomics of microRNA. Trends Genet (2006) 7.75
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev Cell (2003) 7.11
Escape from X inactivation. Cytogenet Genome Res (2002) 5.74
Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing. Cell (2006) 5.61
Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell (1999) 4.08
Meiotic sex chromosome inactivation. Development (2007) 4.03
Postmeiotic sex chromatin in the male germline of mice. Curr Biol (2006) 3.80
Kinetics of spermatogenesis in mammals: seminiferous epithelium cycle and spermatogonial renewal. Physiol Rev (1972) 3.74
Intersection of the RNA interference and X-inactivation pathways. Science (2008) 3.43
H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. Dev Cell (2003) 3.42
RNAi-directed assembly of heterochromatin in fission yeast. FEBS Lett (2005) 3.23
Specific and potent RNAi in the nucleus of human cells. Nat Struct Mol Biol (2005) 3.16
BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation. Curr Biol (2004) 2.67
Argonaute slicing is required for heterochromatic silencing and spreading. Science (2006) 2.48
Pachytene asynapsis drives meiotic sex chromosome inactivation and leads to substantial postmeiotic repression in spermatids. Dev Cell (2006) 2.40
Disruption of imprinted X inactivation by parent-of-origin effects at Tsix. Cell (2000) 2.19
Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse. Hum Mol Genet (2005) 2.12
Synthetic activities during spermatogenesis in the mouse RNA and protein. Exp Cell Res (1965) 2.01
Cloning and expression profiling of testis-expressed microRNAs. Dev Biol (2007) 2.00
Sex chromosomes, recombination, and chromatin conformation. Chromosoma (1993) 1.91
Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nat Genet (2009) 1.88
The XY body: a specialized meiotic chromatin domain. Exp Cell Res (2004) 1.82
X inactivation Xplained. Curr Opin Genet Dev (2007) 1.79
X-chromosome inactivation may explain the difference in viability of XO humans and mice. Nature (1991) 1.73
The behavior of the XY pair in mammals. Int Rev Cytol (1974) 1.69
A physical map of the human Y chromosome. Nature (2001) 1.58
Meiotic silencing and the epigenetics of sex. Chromosome Res (2007) 1.52
X chromosome inactivation in the absence of Dicer. Proc Natl Acad Sci U S A (2009) 1.38
Evolution of X-chromosome inactivation in mammals. Nature (1974) 1.36
Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod (2007) 1.32
RNA and protein actors in X-chromosome inactivation. Cold Spring Harb Symp Quant Biol (2006) 1.26
Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation. PLoS Genet (2006) 1.22
Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. J Cell Sci (2002) 1.22
Sex-chromosome pairing and activity during mammalian meiosis. Bioessays (1992) 1.20
X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse. Genesis (2002) 1.20
X chromosome inactivation studied by injection of a single cell into the mouse blastocyst. Nature (1971) 1.19
miRNA and piRNA localization in the male mammalian meiotic nucleus. Chromosome Res (2008) 1.19
X-chromosome inactivation and human genetic disease. Acta Paediatr Suppl (2002) 1.14
Inactivation of the Zfx gene on the mouse X chromosome. Proc Natl Acad Sci U S A (1991) 1.11
Expression of Xist in mouse germ cells correlates with X-chromosome inactivation. Nat Genet (1992) 1.10
Molecular aspects of XY body formation. Cytogenet Genome Res (2003) 1.03
Telomeres acquire distinct heterochromatin characteristics during siRNA-induced RNA interference in mouse cells. Curr Biol (2008) 0.92
Ring X and other structural X chromosome abnormalities: X inactivation and phenotype. Semin Reprod Med (2001) 0.92
Trimethylation of histone H3 lysine 4 is an epigenetic mark at regions escaping mammalian X inactivation. Epigenetics (2007) 0.90
Meiotic pairing constraints and the activity of sex chromosomes. J Theor Biol (1988) 0.90
Genetic control of mitosis, meiosis and cellular differentiation during mammalian spermatogenesis. Reprod Fertil Dev (1995) 0.88
X-chromosome inactivation: a multi-disciplinary approach. Semin Cell Dev Biol (2003) 0.87
X-chromosome inactivation: the molecular basis of silencing. J Biol (2008) 0.84
Postmeiotic sex chromatin in the male germline of mice. Curr Biol (2006) 3.80
The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod (2004) 3.54
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet (2008) 2.20
Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse. Hum Mol Genet (2005) 2.12
Cloning and expression profiling of testis-expressed microRNAs. Dev Biol (2007) 2.00
Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro. Biol Reprod (2007) 1.94
Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nat Genet (2009) 1.88
A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis. Proc Natl Acad Sci U S A (2013) 1.75
Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning. Proc Natl Acad Sci U S A (2003) 1.73
Systematic variation in mRNA 3'-processing signals during mouse spermatogenesis. Nucleic Acids Res (2006) 1.56
Cloning and expression profiling of testis-expressed piRNA-like RNAs. RNA (2007) 1.52
Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line. PLoS One (2013) 1.35
Sex chromosome silencing in the marsupial male germ line. Proc Natl Acad Sci U S A (2007) 1.34
Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. Biol Reprod (2009) 1.34
Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice. Mol Cell Biol (2002) 1.12
Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis. J Biol Chem (2007) 1.11
Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature (2012) 1.08
Adult mice cloned from migrating primordial germ cells. Proc Natl Acad Sci U S A (2005) 1.08
Key features of the X inactivation process are conserved between marsupials and eutherians. Curr Biol (2009) 1.06
The search for a marsupial XIC reveals a break with vertebrate synteny. Chromosome Res (2007) 1.06
Spontaneous mutagenesis is enhanced in Apex heterozygous mice. Mol Cell Biol (2004) 1.05
Meiotic sex chromosome inactivation in the marsupial Monodelphis domestica. Genesis (2007) 1.03
A conserved E2F6-binding element in murine meiosis-specific gene promoters. Biol Reprod (2008) 1.00
Nucleotide excision repair activity varies among murine spermatogenic cell types. Biol Reprod (2005) 0.99
Dynamic nuclear organization of constitutive heterochromatin during fetal male germ cell development in mice. Biol Reprod (2009) 0.95
Assisted reproductive technologies do not alter mutation frequency or spectrum. Proc Natl Acad Sci U S A (2007) 0.92
In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis. Mol Cell Biol (2007) 0.92
Primary epimutations introduced during intracytoplasmic sperm injection (ICSI) are corrected by germline-specific epigenetic reprogramming. Proc Natl Acad Sci U S A (2012) 0.91
Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice. Hum Mol Genet (2012) 0.90
Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development. Reproduction (2012) 0.89
Mutation spectral changes in spermatogenic cells obtained from old mice. DNA Repair (Amst) (2004) 0.87
A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Biol Reprod (2013) 0.85
Enhanced genetic integrity in mouse germ cells. Biol Reprod (2013) 0.85
Germline genomes--a biological fountain of youth? Sci Aging Knowledge Environ (2003) 0.82
Microarray-based analysis of cell-cycle gene expression during spermatogenesis in the mouse. Biol Reprod (2010) 0.82
Autonomous regulation of sex-specific developmental programming in mouse fetal germ cells. Biol Reprod (2007) 0.82
Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis. Mutat Res (2008) 0.82
Computer-assisted annotation of murine Sertoli cell small RNA transcriptome. Biol Reprod (2013) 0.81
Ontogeny of a demethylation domain and its relationship to activation of tissue-specific transcription. Biol Reprod (2004) 0.81
Conservation of Dnmt1o cytosine methyltransferase in the marsupial Monodelphis domestica. Genesis (2003) 0.80
Epigenetic regulation of genetic integrity is reprogrammed during cloning. Proc Natl Acad Sci U S A (2009) 0.80
A male baboon (Papio hamadryas) with a mosaic 43,XXY/42,XY karyotype. Am J Med Genet A (2006) 0.78
A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells. Nucleic Acids Res (2008) 0.78
Three novel spermatogenesis-specific zinc finger genes. FEBS Lett (2003) 0.77
Sequence-specific promoter elements regulate temporal-specific changes in chromatin required for testis-specific activation of the Pgk2 gene. Reproduction (2013) 0.76
Corrigendum: Parallel evolution of male germline epigenetic poising and somatic development in animals. Nat Genet (2016) 0.76
Absence of ras gene mutations in UV-induced malignant melanomas correlates with a dermal origin of melanocytes in Monodelphis domestica. Cancer Lett (2002) 0.76
Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice. Biol Reprod (2013) 0.75
Derivation of induced pluripotent stem cells from the baboon: a nonhuman primate model for preclinical testing of stem cell therapies. Cell Reprogram (2013) 0.75
Introductory overview to the proceedings of the XXth North American Testis Workshop. J Androl (2009) 0.75