PubRank

Li Ruan

Author PubWeight™ 33.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis 2004 1.65
2 An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus. J Pathol 2005 1.12
3 Association between class III β-tubulin expression and response to paclitaxel/vinorebine-based chemotherapy for non-small cell lung cancer: a meta-analysis. Lung Cancer 2012 1.04
4 Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays. PLoS One 2012 1.04
5 [Chlamydia-like and coronavirus-like agents found in dead cases of atypical pneumonia by electron microscopy]. Zhonghua Yi Xue Za Zhi 2003 0.98
6 Human Coronaviruses HCoV-NL63 and HCoV-HKU1 in Hospitalized Children with Acute Respiratory Infections in Beijing, China. Adv Virol 2011 0.98
7 A recombinant DNA and vaccinia virus prime-boost regimen induces potent long-term T-cell responses to HCV in BALB/c mice. Vaccine 2009 0.90
8 Stability of SARS coronavirus in human specimens and environment and its sensitivity to heating and UV irradiation. Biomed Environ Sci 2003 0.89
9 Human papillomavirus type 16 L1E7 chimeric capsomeres have prophylactic and therapeutic efficacy against papillomavirus in mice. Mol Cancer Ther 2008 0.87
10 Purification, characterization, and modification of T lymphocyte-stimulating polysaccharide from spores of Ganoderma lucidum. Chem Pharm Bull (Tokyo) 2002 0.87
11 Consensus for the management of severe acute respiratory syndrome. Chin Med J (Engl) 2003 0.85
12 Immunogenicity in mice and rhesus monkeys vaccinated with recombinant vaccinia virus expressing bivalent E7E6 fusion proteins from human papillomavirus types 16 and 18. Virol J 2011 0.83
13 Optimisation of prime-boost immunization in mice using novel protein-based and recombinant vaccinia (Tiantan)-based HBV vaccine. PLoS One 2012 0.83
14 Robust immunity and heterologous protection against influenza in mice elicited by a novel recombinant NP-M2e fusion protein expressed in E. coli. PLoS One 2012 0.83
15 Optimization and proficiency testing of a pseudovirus-based assay for detection of HIV-1 neutralizing antibody in China. J Virol Methods 2012 0.83
16 Poly(I:C)/alum mixed adjuvant priming enhances HBV subunit vaccine-induced immunity in mice when combined with recombinant adenoviral-based HBV vaccine boosting. PLoS One 2013 0.82
17 Effect of route of delivery on heterologous protection against HCV induced by an adenovirus vector carrying HCV structural genes. Virol J 2011 0.81
18 [Impact of different adjuvants on immunogenicity of the HBV particle vaccine containing the S + preS1 fusion antigen in Balb/C mice]. Sheng Wu Gong Cheng Xue Bao 2010 0.81
19 Influenza A virus nucleoprotein derived from Escherichia coli or recombinant vaccinia (Tiantan) virus elicits robust cross-protection in mice. Virol J 2012 0.81
20 Recombinant DNA vaccine against neurite outgrowth inhibitors attenuates behavioral deficits and decreases Abeta in an Alzheimer's disease mouse model. Neuropharmacology 2012 0.81
21 IL-15 increases the frequency of effector memory CD8+ T cells in rhesus monkeys immunized with HIV vaccine. Cell Mol Immunol 2010 0.80
22 The novel replication-defective vaccinia virus (Tiantan strain)-based hepatitis C virus vaccine induces robust immunity in macaques. Mol Ther 2013 0.80
23 SARS-CoV spike proteins expressed by the vaccinia virus Tiantan strain: secreted sq protein induces robust neutralization antibody in mice. Viral Immunol 2009 0.80
24 The design and application of DNA chips for early detection of SARS-CoV from clinical samples. J Clin Virol 2005 0.80
25 [Modification of HPV type 16 E6 and E7 genes, and analysis of stability and immunogenicity of the modified proteins]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2002 0.80
26 [Screening for EGFR mutations in lung cancer by a novel real-time PCR with double-loop probe and Sanger DNA sequencing]. Zhonghua Zhong Liu Za Zhi 2013 0.79
27 Enhanced effect of DNA immunization plus in vivo electroporation with a combination of hepatitis B virus core-PreS1 and S-PreS1 plasmids. Clin Vaccine Immunol 2011 0.79
28 [Identification specific T lymphocyte epitopes on E6 protein of human papillomavirus type 18 in mice]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2010 0.78
29 [Development of infectious pseudo-particle harboring three subtypes hepatitis C virus glycoproteins and their application in neutralization assays]. Bing Du Xue Bao 2008 0.78
30 [The 50% effective dose (ED50a) of seasonal spilt influenza vaccine in mice]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2011 0.78
31 [Expression of influenza A3 virus (H3N2) M2 gene in vaccinia virus Tiantan strain]. Bing Du Xue Bao 2007 0.77
32 [Construction and evaluation of hepatitis C virus (HCV) DNA vaccine containing E2-gAD fusion gene]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2010 0.77
33 [Development and comparison of real-time and conventional RT-PCR assay for detection of human coronavirus NL63 and HKU1]. Bing Du Xue Bao 2008 0.77
34 [Characterization of human coronavirus 229E infection among patients with respiratory symptom in Beijing, Oct-Dec, 2007]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2009 0.77
35 [Efficient soluble expression and purification of influenza A nucleoprotein in Escherichia coli]. Bing Du Xue Bao 2011 0.77
36 [Boosting with HBV subunit particle vaccine enhance immune response of novel DNA vaccine consisting of S-PreS1 fusion gene in mice]. Sheng Wu Gong Cheng Xue Bao 2011 0.77
37 [Non-replicating recombinant vaccinia virus expressing HPV16 E6 and E7 proteins elicits anti-tumor immunity in mice]. Zhonghua Zhong Liu Za Zhi 2003 0.76
38 [Peptide mapping of H-2d restricted T-cell epitope against six antigens of HIV-1 subtype B'/C by ELISPOT assay]. Bing Du Xue Bao 2011 0.76
39 TSER polymorphism is not associated with risk of pediatric acute lymphoblastic leukemia: A meta-analysis. Medicine (Baltimore) 2017 0.75
40 [Construction of bicistronic eukaryotic expression vector containing HA and M2 genes derived from high pathogenic avian influenza virus (HPAI) H5N1 (Anhui strain)and its efficient expression in mammalian cells]. Bing Du Xue Bao 2008 0.75
41 [Augmentation of the immunostimulatory effects of plasmid DNA by incorporation of human CpG-oligodeoxynucletide]. Zhonghua Yi Xue Za Zhi 2002 0.75
42 [Construction and identification of the replication-deficient recombinant vaccinia virus co-expressing HPV type 16 L1 and L2 proteins]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2002 0.75
43 [Research and development of M2- and M2e-based broad-spectrum influenza A vaccines]. Bing Du Xue Bao 2011 0.75
44 Experimental study on induction of renal cell carcinoma apoptosis by antisense oligonucleotide targeting survivin. J Huazhong Univ Sci Technolog Med Sci 2004 0.75
45 [Calcineurin subunit B is not an effective adjuvant when combined with a novel HBV protein particle vaccine]. Bing Du Xue Bao 2014 0.75
46 [Consecutive five-year follow-up analysis of specific IgG antibody of 22 cases of SARS patients after recovery]. Bing Du Xue Bao 2010 0.75
47 [Construction of recombinant vaccina virus of HPV16 and its antitumor effect]. Ai Zheng 2005 0.75
48 [Vaccination with three HIV-1 cross neutralizing epitopes fused to HBV S antigen could induce robust antibody immune response in mice]. Bing Du Xue Bao 2008 0.75
49 [The non-replicating recombinant vaccinia virus expressing six genes of HIV-1 can be passaged stably in CEF]. Bing Du Xue Bao 2011 0.75
50 [Construction and identification of non-replication recombinant vaccinia virus co-expressing human papillomavirus type 16 L1/L2/E6/E7 proteins]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2005 0.75
51 [DNA vaccination via in vivo electroporation can elicit specific immune response against highly pathogenic H5N1 influenza viral structural antigens in mice]. Bing Du Xue Bao 2010 0.75
52 [Two HCV vaccines based on adeno-associated virus vectors elicited durable and effective immune responses in mice]. Bing Du Xue Bao 2009 0.75
53 [Prokaryotic expression and purification of human papillomavirus type 11 L2E7 fusion protein vaccine and its immunnogenicity]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2007 0.75
54 [Development and application of a safe SARS-CoV neutralization assay based on lentiviral vectors pseudotyped with SARS-CoV spike protein]. Bing Du Xue Bao 2007 0.75
55 [High expression of HPV16L2N120E7E6 fusion protein in E. coli and its inhibitory effect on tumor growth in mice]. Zhonghua Zhong Liu Za Zhi 2012 0.75
56 [Expression of the human papillomavirus type 16L/E7 fusion protein in E. coli and observation of its immunogenicity in mice]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2006 0.75
57 [Immune protective effectiveness of seasonal influenza spilt vaccine against homologous and heterogonous subtypes of influenza virus in mice]. Bing Du Xue Bao 2011 0.75
58 [Highly efficient expression of codon-optimized human papillomavirus 16 L2E7 gene in Escherichia coli]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2007 0.75
59 [The immunogenicity in mice enhanced significantly via prime-boost vaccination with DNA-based or recombinant vaccinia(Tiantan) viral-based H5N1 vaccine candidates containing multi-structural antigens]. Bing Du Xue Bao 2011 0.75
60 [Antigenicity characterization of six different fragments of SARS-CoV N protein expressed in E. coli]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2012 0.75
61 [Dual gene amplification and selection system with dihydrofolate reductase and glutamine synthetase genes effectively increase the foreign gene expression]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2002 0.75
62 [The high expression of HPV31 and 52 L2 fusion protein in E. coli and detection of its immunogenicity]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2013 0.75
63 [Construction of recombinant vaccinia virus expressing HPV18E7E6 fusion proteins and detection of its immunogenicity in mice]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2008 0.75
64 [CpG-ODN is a potential candidate adjuvant for human vaccines]. Zhonghua Yi Xue Za Zhi 2002 0.75
65 [Enhancement of the immune response in mice with a noval HCV DNA vaccine targeting NS3 to dendritic cells]. Bing Du Xue Bao 2011 0.75
66 [Expression and immunity of multi-HIV B'/C subype genes in replicating DNA vaccines]. Bing Du Xue Bao 2010 0.75
67 [HBV DNA vaccination with electroporation enhances significantly the specific cell-mediated immune response in mice against HBV protein vaccine consisting of S-PreS1 fusion particles]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2010 0.75
68 [Construction of recombinant vaccinia virus co-expressing mutant E6 plus E7 proteins and detection of its immunogenicity and antitumor response]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2002 0.75
69 [Deletion of IV a2 gene from adenoviral genome by lambda-Red recombinase system and packaging of the recombinant adenovirus]. Bing Du Xue Bao 2011 0.75
70 [The expression and preliminary evaluation of HPV6bL2deltaN360E7E6 fusion protein in E. coli for genital warts]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2010 0.75
71 [Expression of IL-6 in recombinant non-replicating vaccinia virus and studying its effects on immunogenicity]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2002 0.75