Published in J Cereb Blood Flow Metab on October 01, 1987
Hydrogen ions kill brain at concentrations reached in ischemia. J Cereb Blood Flow Metab (1987) 1.47
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Increased damage after ischemic stroke in patients with hyperglycemia with or without established diabetes mellitus. Am J Med (1983) 1.53
Hydrogen ions kill brain at concentrations reached in ischemia. J Cereb Blood Flow Metab (1987) 1.47
Brain lactic acidosis and ischemic cell damage: 1. Biochemistry and neurophysiology. J Cereb Blood Flow Metab (1981) 1.43
Carbonic acid buffer changes during complete brain ischemia. Am J Physiol (1986) 1.32
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Changes in extra- and intracellular pH in the brain during and following ischemia in hyperglycemic and in moderately hypoglycemic rats. J Cereb Blood Flow Metab (1986) 1.24
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Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat. II. Regional metabolite levels. Stroke (1980) 1.08
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Acid-base homeostasis in the brain: physiology, chemistry, and neurochemical pathology. Prog Brain Res (1985) 0.95
Acid-induced changes of brain protein buffering. Brain Res (1987) 0.92
An ultrastructural analysis of endothelial change paralleling platelet aggregation in a light/dye model of microvascular insult. Am J Pathol (1983) 0.90
Arterial hypotension induced by horseradish peroxidase in various rat strains. J Histochem Cytochem (1976) 0.86
Effects of lactic acid on astrocytes in primary culture. J Neuropathol Exp Neurol (1987) 0.85
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Ultrastructural observations of an electron dense amorphous layer on selectively damaged endothelial cells, a possible trigger of thrombogenesis in vivo, and its inhibition by nafazatrom. Thromb Res (1984) 0.81
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Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol (1982) 5.58
A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke (1979) 3.78
Alkaline and acid transients in cerebellar microenvironment. J Neurophysiol (1983) 2.21
Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology (1987) 2.12
Characterization of inducible cyclooxygenase in rat brain. J Comp Neurol (1995) 1.94
Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications. Science (1985) 1.91
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Increased damage after ischemic stroke in patients with hyperglycemia with or without established diabetes mellitus. Am J Med (1983) 1.53
Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms. J Neurosci (1993) 1.50
Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia. Ann Neurol (1982) 1.48
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Dynamics of interstitial and intracellular pH in evolving brain infarct. Am J Physiol (1991) 1.43
Selective neuronal vulnerability: morphological and molecular characteristics. Prog Brain Res (1985) 1.43
Optimization of multiplexed bead-based cytokine immunoassays for rat serum and brain tissue. J Neurosci Methods (2004) 1.41
Extracellular ionic variations during spreading depression. Neuroscience (1978) 1.37
Intracellular pH of astrocytes increases rapidly with cortical stimulation. Am J Physiol (1987) 1.33
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Selective glial vulnerability following transient global ischemia in rat brain. J Neuropathol Exp Neurol (1998) 1.31
Intracellular pH transients of mammalian astrocytes. J Neurosci (1989) 1.24
Acid-induced death in neurons and glia. J Neurosci (1991) 1.22
Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo. J Cereb Blood Flow Metab (1997) 1.22
Eicosanoids and nitric oxide influence induction of reactive gliosis from spreading depression in microglia but not astrocytes. J Comp Neurol (1996) 1.22
Hydrogen ion buffering during complete brain ischemia. Brain Res (1985) 1.20
Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production. J Neurochem (1999) 1.19
Delayed neuronal recovery and neuronal death in rat hippocampus following severe cerebral ischemia: possible relationship to abnormalities in neuronal processes. J Cereb Blood Flow Metab (1984) 1.18
Heterogeneous distribution of hydrogen and bicarbonate ions during complete brain ischemia. Prog Brain Res (1985) 1.15
Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats. Proc Natl Acad Sci U S A (1992) 1.15
Calcium waves precede electrophysiological changes of spreading depression in hippocampal organ cultures. J Neurosci (1998) 1.11
Regional energy balance in rat brain after transient forebrain ischemia. J Neurochem (1983) 1.11
Regional protein synthesis in rat brain following acute hemispheric ischemia. J Neurochem (1980) 1.11
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Edema and vascular permeability in cerebral ischemia: comparison between ischemic neuronal damage and infarction. J Neuropathol Exp Neurol (1982) 1.06
Long-term elevation of cyclooxygenase-2, but not lipoxygenase, in regions synaptically distant from spreading depression. J Comp Neurol (1996) 1.02
The CBF threshold and dynamics for focal cerebral infarction in spontaneously hypertensive rats. J Cereb Blood Flow Metab (1992) 1.00
Astrocytic clasmatodendrosis in hippocampal organ culture. Glia (2001) 0.96
Bicarbonate and ammonia changes in brain during spreading depression. Can J Physiol Pharmacol (1987) 0.95
The effects of extracellular acidosis on neurons and glia in vitro. J Cereb Blood Flow Metab (1989) 0.93
Glutathione and ascorbate during ischemia and postischemic reperfusion in rat brain. J Neurochem (1980) 0.92
Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats. Neurosci Lett (1991) 0.92
Synthesis of heat shock proteins in rat brain cortex after transient ischemia. J Cereb Blood Flow Metab (1986) 0.92
Acid-induced changes of brain protein buffering. Brain Res (1987) 0.92
The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats. J Neurosci (1991) 0.92
DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. J Cereb Blood Flow Metab (1997) 0.91
Continuous nimodipine treatment attenuates cortical infarction in rats subjected to 24 hours of focal cerebral ischemia. J Cereb Blood Flow Metab (1990) 0.91
Responses of CA1 pyramidal neurons in rat hippocampus to transient forebrain ischemia: an in vivo intracellular recording study. Neurosci Lett (1994) 0.90
Selective gene expression in focal cerebral ischemia. J Cereb Blood Flow Metab (1986) 0.88
Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology. J Neurosci (1996) 0.88
Transient global ischemia in rats yields striatal projection neuron and interneuron loss resembling that in Huntington's disease. Exp Neurol (2000) 0.88
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Nimodipine pretreatment improves cerebral blood flow and reduces brain edema in conscious rats subjected to focal cerebral ischemia. J Cereb Blood Flow Metab (1990) 0.87
The ischemic penumbra, injury thresholds, and the therapeutic window for acute stroke. Ann Neurol (1994) 0.87
Behavioral performance of rats following transient forebrain ischemia. Stroke (1984) 0.87
Cytoskeletal actin gates a Cl- channel in neocortical astrocytes. J Neurosci (1998) 0.86
Protein synthesis in postischemic rat brain: a two-dimensional electrophoretic analysis. J Cereb Blood Flow Metab (1986) 0.86
Painful tic convulsif. J Neurol Neurosurg Psychiatry (1977) 0.86
NMDA and non-NMDA receptor gene expression following global brain ischemia in rats: effect of NMDA and non-NMDA receptor antagonists. J Neurochem (1994) 0.85
Sodium liquid ion exchanger microelectrode used to measure large extracellular sodium transients. Science (1976) 0.84
Chloride and potassium changes measured during spreading depression in catfish cerebellum. Brain Res (1975) 0.84
Prolonged enhancement and depression of synaptic transmission in CA1 pyramidal neurons induced by transient forebrain ischemia in vivo. Neuroscience (1998) 0.84
Local cerebral glucose metabolism during controlled hypoxemia in rats. Science (1979) 0.83
Altered mitochondrial respiration in selectively vulnerable brain subregions following transient forebrain ischemia in the rat. J Neurochem (1987) 0.83
Reference and working memory of rats following hippocampal damage induced by transient forebrain ischemia. Physiol Behav (1986) 0.83
Neuronal nitric oxide synthase expression is induced in neocortical astrocytes after spreading depression. J Cereb Blood Flow Metab (1998) 0.83
Septo-hippocampal deafferentation protects CA1 neurons against ischemic injury. Brain Res (1990) 0.83
Determination of extracellular bicarbonate and carbon dioxide concentrations in brain slices using carbonate and pH-selective microelectrodes. J Neurosci Methods (1994) 0.82
Focal elevations in neocortical interstitial K+ produced by stimulation of the fastigial nucleus in rat. Brain Res (1991) 0.81
Electrophysiological changes of CA3 neurons and dentate granule cells following transient forebrain ischemia. Brain Res (1998) 0.81
Electrophysiological changes of CA1 pyramidal neurons following transient forebrain ischemia: an in vivo intracellular recording and staining study. J Neurophysiol (1996) 0.81
Transient global ischemia induces dynamic changes in the expression of bFGF and the FGF receptor. Brain Res Mol Brain Res (1994) 0.80
Changes in membrane properties of CA1 pyramidal neurons after transient forebrain ischemia in vivo. Neuroscience (1999) 0.80
Intracellular pH rises and astrocytes swell after portacaval anastomosis in rats. Am J Physiol (1991) 0.80
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In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose. J Cereb Blood Flow Metab (1986) 0.78
Cerebral blood flow in the four-vessel occlusion rat model. Stroke (1984) 0.78
Reactive astrocytes express NADPH diaphorase in vivo after transient ischemia. Neurosci Lett (1993) 0.77
Retention of reference memory following ischemic hippocampal damage. Physiol Behav (1987) 0.77
Compartmentation of acid-base balance in brain during complete ischemia. Neurochem Pathol (1989) 0.77
Posthoc phosphorylation of proteins derived from ischemic rat hippocampus, striatum and neocortex. Brain Res (1990) 0.77
Astroglial acid-base dynamics in hyperglycemic and normoglycemic global ischemia. Neurosci Biobehav Rev (1997) 0.77
Carbonic acid buffer species measured in real time with an intracellular microelectrode array. Am J Physiol (1991) 0.77
Uptake of radiolabeled ions in normal and ischemia-damaged brain. Ann Neurol (1986) 0.77
Inhibition of lactate production in rat brain extracts and synaptosomes by 3-[4-(reduced 3-pyridine aldehyde-adenine dinucleotide)]-pyruvate. J Neurochem (1987) 0.77
Ischemic brain edema requires tissue necrosis. Trans Am Neurol Assoc (1980) 0.77
The therapeutic window in ischemic brain injury. Curr Opin Neurol (1995) 0.76
Chorea complicating oral contraceptive therapy. Case report and review of the literature. Am J Med (1978) 0.75
Failure of GM1 ganglioside to influence outcome in experimental focal ischemia. Stroke (1992) 0.75
Severe bilateral tremor in a liver transplant recipient taking cyclosporine. Mov Disord (1998) 0.75
Barbiturate exacerbation of ischemic brain damage following bilateral hemispheric ischemia in the rat. Trans Am Neurol Assoc (1979) 0.75
Potassium, calcium, chloride and sodium changes in extracellular space during spreading depression in cerebellum [proceedings]. Arzneimittelforschung (1978) 0.75
Regional cerebral glucose metabolism during hypoxia. Adv Neurol (1979) 0.75