Published in Trials on February 27, 2017
The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med (2001) 76.04
Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology (1983) 40.64
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet (2001) 31.74
The timed "Up & Go": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc (1991) 31.17
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol (2011) 25.66
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem (1969) 15.62
The mini-mental state examination: a comprehensive review. J Am Geriatr Soc (1992) 15.32
The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol (1989) 13.32
Perceived exertion as an indicator of somatic stress. Scand J Rehabil Med (1970) 12.81
Interrater reliability of a modified Ashworth scale of muscle spasticity. Phys Ther (1987) 12.21
Axonal transection in the lesions of multiple sclerosis. N Engl J Med (1998) 12.21
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials. BMJ (2013) 9.01
Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain (1999) 4.41
Axonal damage in acute multiple sclerosis lesions. Brain (1997) 3.88
Measuring the impact of MS on walking ability: the 12-Item MS Walking Scale (MSWS-12). Neurology (2003) 3.75
The Multiple Sclerosis Impact Scale (MSIS-29): a new patient-based outcome measure. Brain (2001) 3.51
Dealing with missing outcome data in randomized trials and observational studies. Am J Epidemiol (2011) 3.03
Observations on an enzymic method for the estimation of pyruvate in blood. Clin Chim Acta (1962) 2.70
A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood. Nat Protoc (2007) 2.59
GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J Immunol (2007) 2.56
Evaluation of the six-minute walk in multiple sclerosis subjects and healthy controls. Mult Scler (2007) 2.36
Physical rehabilitation has a positive effect on disability in multiple sclerosis patients. Neurology (1999) 2.27
Controlled randomised crossover trial of the effects of physiotherapy on mobility in chronic multiple sclerosis. J Neurol Neurosurg Psychiatry (2001) 2.23
Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes. Lancet Neurol (2005) 2.01
Exercise therapy for multiple sclerosis. Cochrane Database Syst Rev (2005) 1.69
The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Prog Neurobiol (2011) 1.61
Risks of falls in subjects with multiple sclerosis. Arch Phys Med Rehabil (2002) 1.58
Brain-derived neurotrophic factor: a dynamic gatekeeper of neural plasticity. Curr Mol Pharmacol (2010) 1.57
Cytoprotective protein C pathways and implications for stroke and neurological disorders. Trends Neurosci (2011) 1.53
Multiple sclerosis and physical exercise: recommendations for the application of resistance-, endurance- and combined training. Mult Scler (2007) 1.48
Validity of six balance disorders scales in persons with multiple sclerosis. Disabil Rehabil (2006) 1.48
The effects of robot-assisted gait training in progressive multiple sclerosis: A randomized controlled trial. Mult Scler (2015) 1.40
The morbidity of multiple sclerosis. Q J Med (1992) 1.21
Motor determinants of gait in 100 ambulatory patients with multiple sclerosis. Mult Scler (2005) 1.15
Longitudinal optical imaging study for locomotor recovery after stroke. Stroke (2003) 1.12
A comparison of two physiotherapy treatment approaches to improve walking in multiple sclerosis: a pilot randomized controlled study. Clin Rehabil (1998) 1.11
Improving gait in multiple sclerosis using robot-assisted, body weight supported treadmill training. Neurorehabil Neural Repair (2008) 1.10
Can aerobic treadmill training reduce the effort of walking and fatigue in people with multiple sclerosis: a pilot study. Mult Scler (2007) 1.10
PDGF and FGF2 regulate oligodendrocyte progenitor responses to demyelination. J Neurobiol (2003) 1.07
Genetics and pathogenesis of multiple sclerosis. Semin Immunol (2009) 1.06
Functional brain reorganization for hand movement in patients with multiple sclerosis: defining distinct effects of injury and disability. Brain (2002) 1.05
Resistance training improves gait kinematics in persons with multiple sclerosis. Arch Phys Med Rehabil (2005) 1.03
Robot-assisted gait training in multiple sclerosis: a pilot randomized trial. Mult Scler (2007) 1.00
A longitudinal fMRI study on motor activity in patients with multiple sclerosis. Brain (2005) 0.98
A novel colorimetric assay for the determination of lysophosphatidic acid in plasma using an enzymatic cycling method. Clin Chim Acta (2003) 0.98
Quality of life and impairment in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry (2005) 0.98
Evaluation of the 9-item Patient Health Questionnaire (PHQ-9) as an assessment instrument for symptoms of depression in patients with multiple sclerosis. Postgrad Med (2012) 0.96
Effects of 12 weeks of supported treadmill training on functional ability and quality of life in progressive multiple sclerosis: a pilot study. Arch Phys Med Rehabil (2011) 0.95
Relating axonal injury to functional recovery in MS. Neurology (2000) 0.95
Robot-assisted gait training in multiple sclerosis patients: a randomized trial. Mult Scler (2011) 0.95
Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression. J Neurol Sci (2008) 0.95
Resting muscle oxygen consumption by near-infrared spectroscopy in peripheral arterial disease: A parameter to be considered in a clinical setting? Angiology (2010) 0.95
The levels of circulating TRAIL at the onset of type 1 diabetes are markedly decreased in patients with ketoacidosis and with the highest insulin requirement. Acta Diabetol (2013) 0.94
Robotic-assisted step training (lokomat) not superior to equal intensity of over-ground rehabilitation in patients with multiple sclerosis. Neurorehabil Neural Repair (2011) 0.93
Effects of a short outpatient rehabilitation treatment on disability of multiple sclerosis patients--a randomised controlled trial. J Neurol (2003) 0.93
Neuroplasticity and functional recovery in multiple sclerosis. Nat Rev Neurol (2012) 0.93
Locomotor training using body weight support on a treadmill improves mobility in persons with multiple sclerosis: a pilot study. Mult Scler (2007) 0.92
Neuroprotective role of fibroblast growth factor-2 in experimental autoimmune encephalomyelitis. Immunology (2011) 0.91
An ultrasound model to calculate the brain blood outflow through collateral vessels: a pilot study. BMC Neurol (2013) 0.91
Neural Plasticity in Multiple Sclerosis: The Functional and Molecular Background. Neural Plast (2015) 0.91
The limits of functional reorganization in multiple sclerosis. Neurology (2010) 0.90
The central role of mitochondria in axonal degeneration in multiple sclerosis. Mult Scler (2014) 0.88
Cerebral plasticity in multiple sclerosis: insights from fMRI. Mult Scler (2002) 0.88
Robot-assisted vs. sensory integration training in treating gait and balance dysfunctions in patients with multiple sclerosis: a randomized controlled trial. Front Hum Neurosci (2014) 0.87
Functional cortical changes of the sensorimotor network are associated with clinical recovery in multiple sclerosis. Hum Brain Mapp (2008) 0.87
Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic parameters in patients affected by chronic venous disease. Cytokine (2013) 0.87
Overview of primary progressive multiple sclerosis (PPMS): similarities and differences from other forms of MS, diagnostic criteria, pros and cons of progressive diagnosis. Mult Scler (2004) 0.85
Treadmill training in multiple sclerosis: can body weight support or robot assistance provide added value? A systematic review. Mult Scler Int (2012) 0.85
Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis. J Rehabil Res Dev (2011) 0.84
Altered serum content of brain-derived neurotrophic factor isoforms in multiple sclerosis. J Neurol Sci (2012) 0.82
Treadmill exercise in early mutiple sclerosis: a case series study. Eur J Phys Rehabil Med (2009) 0.82
Serum and CSF PDGF-AA and FGF-2 in relapsing-remitting multiple sclerosis: a case-control study. Eur J Neurol (2011) 0.81
CD4(+) T regulatory cells are more resistant to DNA damage compared to CD4(+) T effector cells as revealed by flow cytometric analysis. Cytometry A (2011) 0.80
Muscle oxygen consumption by NIRS and mobility in multiple sclerosis patients. BMC Neurol (2013) 0.80
Does robot-assisted gait training ameliorate gait abnormalities in multiple sclerosis? A pilot randomized-control trial. NeuroRehabilitation (2013) 0.79
Cerebrospinal fluid lactate is associated with multiple sclerosis disease progression. J Neuroinflammation (2016) 0.78
An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis. Thromb Haemost (2014) 0.78
Detection of reduced interhemispheric cortical communication during task execution in multiple sclerosis patients using functional near-infrared spectroscopy. J Biomed Opt (2014) 0.77
Functional status and quality of life of stroke survivors undergoing rehabilitation programmes in a hospital setting. NeuroRehabilitation (2014) 0.76
Combination of robot-assisted and conventional body-weight-supported treadmill training improves gait in persons with multiple sclerosis: a pilot study. J Neurol Phys Ther (2013) 0.76
Activated factor VII-antithrombin complex predicts mortality in patients with stable coronary artery disease: a cohort study. J Thromb Haemost (2016) 0.76
Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury. J Mol Cell Cardiol (2014) 1.03
The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition. Oncotarget (2015) 0.80
Novel frontiers in calcium signaling: A possible target for chemotherapy. Pharmacol Res (2015) 0.77
Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques. Nat Protoc (2016) 0.76
PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth. Nature (2017) 0.76
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations. Blood (2017) 0.75
Protein Kinase C β: a New Target Therapy to Prevent the Long-Term Atypical Antipsychotic-Induced Weight Gain. Neuropsychopharmacology (2017) 0.75
Other bricks for the correct construction of the mitochondrial permeability transition pore complex. Cell Death Dis (2017) 0.75
Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals. J Neurol Neurosurg Psychiatry (2017) 0.75
Regulation of Endoplasmic Reticulum-Mitochondria Ca(2+) Transfer and Its Importance for Anti-Cancer Therapies. Front Oncol (2017) 0.75
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies. Hum Psychopharmacol (2017) 0.75