miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28276476)

Published in Sci Rep on March 09, 2017

Authors

Cheen P Khoo1,2, Maria G Roubelakis1,2,3,4, Jack B Schrader1,2,5, Grigorios Tsaknakis1,2,6, Rebecca Konietzny7, Benedikt Kessler7, Adrian L Harris8, Suzanne M Watt1,2

Author Affiliations

1: Stem Cell Research, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9BQ, UK.
2: Stem Cell Research, NHS Blood and Transplant, Oxford, OX3 9BQ, UK.
3: Laboratory of Biology, National and Kapodistrian University of Athens Medical School, Athens 115 27, Greece.
4: Cell and Gene Therapy Laboratory, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, 11527, Greece.
5: Department of Biology, University of York, York, YO10 5DD, UK.
6: Institute of Molecular Biology and Biotechnology, Foundation of Research &Technology, GR-70013 Heraklion, Crete.
7: Target Discovery Institute, NDM Research Building, Nuffield Department of Medicine, University of Oxford, OX3 7FZ, UK.
8: The Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.

Articles citing this

Biological Function of MicroRNA193a-3p in Health and Disease. Int J Genomics (2017) 0.75

Articles cited by this

MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood (2004) 7.21

Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res (2008) 3.50

The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol (2001) 3.43

Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells. Blood (2010) 2.80

Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood (2004) 2.76

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation. J Cell Biol (2004) 2.75

Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine. J Immunol (2006) 2.57

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. J Exp Med (2012) 2.35

Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J Clin Invest (2010) 2.32

High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res (2007) 1.89

Regulation of tumor angiogenesis by integrin-linked kinase (ILK). Cancer Cell (2004) 1.82

Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule. Am J Pathol (2005) 1.75

Human endothelial progenitor cells. Cold Spring Harb Perspect Med (2012) 1.68

Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia. Circ Res (2014) 1.61

Dysregulation of angiogenesis-related microRNAs in endothelial progenitor cells from patients with coronary artery disease. Biochem Biophys Res Commun (2010) 1.59

MicroRNA-34a regulation of endothelial senescence. Biochem Biophys Res Commun (2010) 1.58

MicroRNA-16 affects key functions of human endothelial progenitor cells. J Leukoc Biol (2013) 1.56

Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1. Oncogene (2012) 1.37

High-mobility group box 1 protein in human and murine skin: involvement in wound healing. J Invest Dermatol (2008) 1.36

Transplanted late outgrowth endothelial progenitor cells as cell therapy product for stroke. Stem Cell Rev (2011) 1.13

A comparison of methods for quantifying angiogenesis in the Matrigel assay in vitro. Tissue Eng Part C Methods (2011) 1.10

Vascular incorporation of endothelial colony-forming cells is essential for functional recovery of murine ischemic tissue following cell therapy. Arterioscler Thromb Vasc Biol (2011) 1.10

Circulating and tissue resident endothelial progenitor cells. J Cell Physiol (2014) 1.07

Human endothelial colony-forming cells serve as trophic mediators for mesenchymal stem cell engraftment via paracrine signaling. Proc Natl Acad Sci U S A (2014) 1.06

Gain-of-function microRNA screens identify miR-193a regulating proliferation and apoptosis in epithelial ovarian cancer cells. Int J Oncol (2013) 1.06

The angiogenic properties of mesenchymal stem/stromal cells and their therapeutic potential. Br Med Bull (2013) 1.04

High-mobility group box-1 mediates toll-like receptor 4-dependent angiogenesis. Arterioscler Thromb Vasc Biol (2011) 1.03

The impact of proliferative potential of umbilical cord-derived endothelial progenitor cells and hypoxia on vascular tubule formation in vitro. Stem Cells Dev (2009) 0.95

High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury. J Vasc Surg (2011) 0.95

Overexpression of high mobility group box 1 and 2 is associated with the progression and angiogenesis of human bladder carcinoma. Oncol Lett (2012) 0.95

Human vasculogenic cells form functional blood vessels and mitigate adverse remodeling after ischemia reperfusion injury in rats. Angiogenesis (2013) 0.94

Intracerebroventricular transplantation of ex vivo expanded endothelial colony-forming cells restores blood-brain barrier integrity and promotes angiogenesis of mice with traumatic brain injury. J Neurotrauma (2013) 0.93

miR-193a-3p functions as a tumor suppressor in lung cancer by down-regulating ERBB4. J Biol Chem (2014) 0.93

MicroRNAs and Endothelial (Dys) Function. J Cell Physiol (2015) 0.93

Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization. PLoS One (2013) 0.92

Existence, functional impairment, and lung repair potential of endothelial colony-forming cells in oxygen-induced arrested alveolar growth. Circulation (2014) 0.91

Changes in the frequency and in vivo vessel-forming ability of rhesus monkey circulating endothelial colony-forming cells across the lifespan (birth to aged). Pediatr Res (2011) 0.91

Endothelial progenitor cells and their potential therapeutic applications. Regen Med (2008) 0.91

Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension. Pulm Circ (2012) 0.90

Ecto-5'-nucleotidase (CD73) promotes tumor angiogenesis. Clin Exp Metastasis (2013) 0.90

Selective Interference Targeting of Lnk in Umbilical Cord-Derived Late Endothelial Progenitor Cells Improves Vascular Repair, Following Hind Limb Ischemic Injury, via Regulation of JAK2/STAT3 Signaling. Stem Cells (2015) 0.89

The ever-expanding role of HIF in tumour and stromal biology. Nat Cell Biol (2016) 0.89

Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model. Hepatology (2012) 0.88

A brief primer on microRNAs and their roles in angiogenesis. Vasc Cell (2013) 0.88

miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma. Oncotarget (2015) 0.88

Patient-derived endothelial progenitor cells improve vascular graft patency in a rodent model. Acta Biomater (2011) 0.87

Role of high mobility group box 1 (HMGB1) in wound healing. J Surg Res (2011) 0.87

A novel function for the haemopoietic supportive murine bone marrow MS-5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis. Br J Haematol (2012) 0.86

WKYMVm-induced activation of formyl peptide receptor 2 stimulates ischemic neovasculogenesis by promoting homing of endothelial colony-forming cells. Stem Cells (2014) 0.86

Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene. Arterioscler Thromb Vasc Biol (2004) 0.85

Effects of obstetric factors and storage temperatures on the yield of endothelial colony forming cells from umbilical cord blood. Angiogenesis (2011) 0.84

Inhibition of CD73 stimulates the migration and invasion of B16F10 melanoma cells in vitro, but results in impaired angiogenesis and reduced melanoma growth in vivo. Oncol Rep (2013) 0.83

Targeting of integrin-linked kinase with a small interfering RNA inhibits endothelial cell migration, proliferation and tube formation in vitro. Ophthalmic Res (2009) 0.82

Prospective surface marker-based isolation and expansion of fetal endothelial colony-forming cells from human term placenta. Stem Cells Transl Med (2013) 0.81

MicroRNAs: Key regulators of endothelial progenitor cell functions. Clin Chim Acta (2015) 0.81

A chemically defined carrier for the delivery of human mesenchymal stem/stromal cells to skin wounds. Tissue Eng Part C Methods (2011) 0.81

The hematopoietic chemokine CXCL12 promotes integration of human endothelial colony forming cell-derived cells into immature vessel networks. Stem Cells Dev (2014) 0.80

Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1. J Virol (2014) 0.80

Functional Differences Between Placental Micro- and Macrovascular Endothelial Colony-Forming Cells. Stem Cells Transl Med (2016) 0.80

Genistein promotes endothelial colony-forming cell (ECFC) bioactivities and cardiac regeneration in myocardial infarction. PLoS One (2014) 0.80

The sulfated polysaccharide fucoidan rescues senescence of endothelial colony-forming cells for ischemic repair. Stem Cells (2015) 0.80

HMGB1 may act via RAGE to promote angiogenesis in the later phase after intracerebral hemorrhage. Neuroscience (2015) 0.79

Microvessel networks [corrected] pre-formed in artificial clinical grade dermal substitutes in vitro using cells from haematopoietic tissues. Burns (2012) 0.79

Key Role of DAMP in Inflammation, Cancer, and Tissue Repair. Clin Ther (2016) 0.79

Targeting of integrin-linked kinase with small interfering RNA inhibits VEGF-induced angiogenesis in retinal endothelial cells. Ophthalmic Res (2012) 0.78

Specific Activation of A3, A2A and A1 Adenosine Receptors in CD73-Knockout Mice Affects B16F10 Melanoma Growth, Neovascularization, Angiogenesis and Macrophage Infiltration. PLoS One (2016) 0.77

High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization. Am J Physiol Lung Cell Mol Physiol (2014) 0.77

Judging a proangiogenic cell by its cover. Blood (2009) 0.77

Self-Renewal and High Proliferative Colony Forming Capacity of Late-Outgrowth Endothelial Progenitors Is Regulated by Cyclin-Dependent Kinase Inhibitors Driven by Notch Signaling. Stem Cells (2016) 0.77

Editorial: Early and late endothelial progenitor cells are miR-tually exclusive. J Leukoc Biol (2013) 0.77

Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis. Oncoimmunology (2016) 0.76

Integrin-Linked Kinase Senses Hypoxia During Scar Angiogenesis. Int J Low Extrem Wounds (2016) 0.76

Intravenous Administration of Endothelial Colony-Forming Cells Overexpressing Integrin β1 Augments Angiogenesis in Ischemic Legs. Stem Cells Transl Med (2015) 0.76