Published in Elife on March 10, 2017
NIH Image to ImageJ: 25 years of image analysis. Nat Methods (2012) 84.41
Fiji: an open-source platform for biological-image analysis. Nat Methods (2012) 56.92
The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39
Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature (1999) 8.61
Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature (1996) 7.94
Cofilin promotes actin polymerization and defines the direction of cell motility. Science (2004) 5.12
The PAR proteins: fundamental players in animal cell polarization. Dev Cell (2007) 4.92
Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin. Mol Cell (2006) 4.88
Three-dimensional reconstruction of F-actin, thin filaments and decorated thin filaments. J Mol Biol (1970) 4.82
Methods for cell and particle tracking. Methods Enzymol (2012) 4.80
Flexibility of actin filaments derived from thermal fluctuations. Effect of bound nucleotide, phalloidin, and muscle regulatory proteins. J Biol Chem (1995) 4.78
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins. Nature (2000) 4.73
Cofilin produces newly polymerized actin filaments that are preferred for dendritic nucleation by the Arp2/3 complex. Curr Biol (2002) 3.06
Tropomyosin-based regulation of the actin cytoskeleton in time and space. Physiol Rev (2008) 2.73
Tropomyosin binding to F-actin protects the F-actin from disassembly by brain actin-depolymerizing factor (ADF). Cell Motil (1982) 2.38
A molecular pathway for myosin II recruitment to stress fibers. Curr Biol (2011) 2.25
Structural organization of the actin cytoskeleton at sites of clathrin-mediated endocytosis. Curr Biol (2011) 2.18
Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics. J Cell Biol (2002) 2.15
Self-organization in cell biology: a brief history. Nat Rev Mol Cell Biol (2008) 2.13
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge. J Cell Sci (2002) 2.11
Cofilin increases the bending flexibility of actin filaments: implications for severing and cell mechanics. J Mol Biol (2008) 1.91
Actin network architecture can determine myosin motor activity. Science (2012) 1.89
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension. J Cell Sci (2004) 1.89
Regulation of cell polarity by microtubules in fission yeast. J Cell Biol (1998) 1.88
Actin-filament stochastic dynamics mediated by ADF/cofilin. Curr Biol (2007) 1.82
Tropomyosin: crystal structure, polymorphism and molecular interactions. J Mol Biol (1969) 1.79
Dynamic study of F-actin by quasielastic scattering of laser light. J Mol Biol (1971) 1.76
Functional alpha-tropomyosin produced in Escherichia coli. A dipeptide extension can substitute the amino-terminal acetyl group. J Biol Chem (1994) 1.72
Functional properties of non-muscle tropomyosin isoforms. Curr Opin Cell Biol (1994) 1.64
Profilin regulates F-actin network homeostasis by favoring formin over Arp2/3 complex. Dev Cell (2014) 1.61
Yeast actin patches are networks of branched actin filaments. J Cell Biol (2004) 1.55
Cofilin tunes the nucleotide state of actin filaments and severs at bare and decorated segment boundaries. Curr Biol (2011) 1.55
Roles of a fimbrin and an alpha-actinin-like protein in fission yeast cell polarization and cytokinesis. Mol Biol Cell (2001) 1.55
Solution NMR structure of the junction between tropomyosin molecules: implications for actin binding and regulation. J Mol Biol (2006) 1.52
Building distinct actin filament networks in a common cytoplasm. Curr Biol (2011) 1.43
Acetylation regulates tropomyosin function in the fission yeast Schizosaccharomyces pombe. J Cell Sci (2007) 1.39
Homeostatic actin cytoskeleton networks are regulated by assembly factor competition for monomers. Curr Biol (2014) 1.38
Tropomyosin isoforms and reagents. Bioarchitecture (2011) 1.37
Fimbrin and tropomyosin competition regulates endocytosis and cytokinesis kinetics in fission yeast. Curr Biol (2010) 1.37
How cofilin severs an actin filament. Biophys Rev (2009) 1.36
Actin-depolymerizing protein Adf1 is required for formation and maintenance of the contractile ring during cytokinesis in fission yeast. Mol Biol Cell (2006) 1.33
Three's company: the fission yeast actin cytoskeleton. Trends Cell Biol (2010) 1.28
Differential regulation of unconventional fission yeast myosins via the actin track. Curr Biol (2010) 1.21
Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast. J Cell Biol (2012) 1.20
Efficient site-specific labeling of proteins via cysteines. Bioconjug Chem (2008) 1.17
Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring. J Cell Biol (2011) 1.17
Role of tropomyosin in formin-mediated contractile ring assembly in fission yeast. Mol Biol Cell (2009) 1.17
Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin. Proc Natl Acad Sci U S A (2014) 1.17
Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. J Biol Chem (2011) 1.17
Formins regulate actin filament flexibility through long range allosteric interactions. J Biol Chem (2006) 1.15
Competition between DNA methylation and transcription factors determines binding of NRF1. Nature (2015) 1.14
Tropomyosin - master regulator of actin filament function in the cytoskeleton. J Cell Sci (2015) 1.13
The stability of tropomyosin, a two-stranded coiled-coil protein, is primarily a function of the hydrophobicity of residues at the helix-helix interface. Biochemistry (1995) 1.09
Interactions among a fimbrin, a capping protein, and an actin-depolymerizing factor in organization of the fission yeast actin cytoskeleton. Mol Biol Cell (2001) 1.08
Tropomyosin and ADF/cofilin as collaborators and competitors. Adv Exp Med Biol (2008) 1.06
A periodic pattern of evolutionarily conserved basic and acidic residues constitutes the binding interface of actin-tropomyosin. J Biol Chem (2013) 1.04
Conformational changes in actin filaments induced by formin binding to the barbed end. Biophys J (2006) 1.04
Formins determine the functional properties of actin filaments in yeast. Curr Biol (2014) 1.01
Single-molecule imaging of a three-component ordered actin disassembly mechanism. Nat Commun (2015) 0.98
Architecture dependence of actin filament network disassembly. Curr Biol (2015) 0.97
Competitive displacement of cofilin can promote actin filament severing. Biochem Biophys Res Commun (2013) 0.96
Fission yeast tropomyosin specifies directed transport of myosin-V along actin cables. Mol Biol Cell (2013) 0.96
Actin filament severing by cofilin dismantles actin patches and produces mother filaments for new patches. Curr Biol (2013) 0.96
Actin and Actin-Binding Proteins. Cold Spring Harb Perspect Biol (2016) 0.94
A molecular evolution approach to study the roles of tropomyosin in fission yeast. PLoS One (2013) 0.94
Aip1 destabilizes cofilin-saturated actin filaments by severing and accelerating monomer dissociation from ends. Curr Biol (2014) 0.94
Aip1 promotes actin filament severing by cofilin and regulates constriction of the cytokinetic contractile ring. J Biol Chem (2014) 0.94
Architecture and Connectivity Govern Actin Network Contractility. Curr Biol (2016) 0.92
Cooperative binding of tropomyosin to actin. Adv Exp Med Biol (2008) 0.91
Single-molecule visualization of a formin-capping protein 'decision complex' at the actin filament barbed end. Nat Commun (2015) 0.90
Principles of PAR polarity in Caenorhabditis elegans embryos. Nat Rev Mol Cell Biol (2013) 0.88
Effects of the amino-terminal regions of tropomyosin and troponin T on thin filament assembly. J Biol Chem (1992) 0.88
Arp2/3 complex and cofilin modulate binding of tropomyosin to branched actin networks. Curr Biol (2015) 0.87
Single-molecule imaging and kinetic analysis of cooperative cofilin-actin filament interactions. Proc Natl Acad Sci U S A (2014) 0.86
High-speed depolymerization at actin filament ends jointly catalysed by Twinfilin and Srv2/CAP. Nat Cell Biol (2015) 0.84
Mechanical stress and network structure drive protein dynamics during cytokinesis. Curr Biol (2015) 0.83
Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind co-operatively to actin and regulate myosin. Biochem J (2011) 0.82
Sorting competition with membrane-permeable peptides in intact epithelial cells revealed discrimination of transmembrane proteins not only at the trans-Golgi network but also at pre-Golgi stages. J Biol Chem (2004) 0.82
Direct observation of tropomyosin binding to actin filaments. Cytoskeleton (Hoboken) (2015) 0.81
Analysis of biophysical and functional consequences of tropomyosin-fluorescent protein fusions. FEBS Lett (2016) 0.79
Quantitative analysis of tropomyosin linear polymerization equilibrium as a function of ionic strength. J Biol Chem (2001) 0.79
In Vitro Biochemical Characterization of Cytokinesis Actin-Binding Proteins. Methods Mol Biol (2016) 0.77
Cooperative binding of n-mers with steric hindrance to finite and infinite one-dimensional lattices. Biopolymers (1982) 0.76
Single Filaments to Reveal the Multiple Flavors of Actin. Biophys J (2016) 0.76
Fascin- and α-Actinin-Bundled Networks Contain Intrinsic Structural Features that Drive Protein Sorting. Curr Biol (2016) 0.76
Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast. Nat Commun (2016) 0.76
Evolutionarily conserved sites in yeast tropomyosin function in cell polarity, transport and contractile ring formation. Biol Open (2015) 0.76
The bacterial virulence factors VopL and VopF nucleate actin from the pointed end. J Cell Biol (2017) 0.81
Coarse-grained Directed Simulation. J Chem Theory Comput (2017) 0.75