Published in J Mol Biol on June 14, 1970
Actin in dividing cells: contractile ring filaments bind heavy meromyosin. Proc Natl Acad Sci U S A (1973) 4.61
The organization of actin filaments in the stereocilia of cochlear hair cells. J Cell Biol (1980) 3.64
Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity. J Cell Biol (1992) 3.21
Actin filament organization in the fish keratocyte lamellipodium. J Cell Biol (1995) 3.20
Isolation and characterization of myosin and two myosin fragments from human blood platelets. Proc Natl Acad Sci U S A (1971) 3.09
The effect of the performance of work on total energy output and metabolism during muscular contraction. J Physiol (1974) 2.90
Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J Cell Biol (1987) 2.57
Actin from Saccharomyces cerevisiae. Mol Cell Biol (1982) 2.26
Visualization of actin fibers associated with the cell membrane in amoebae of Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 2.19
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing. Cell (2010) 1.94
Fluorescence photobleaching recovery in solutions of labeled actin. Biophys J (1981) 1.94
Polarization from a helix of fluorophores and its relation to that obtained from muscle. Biophys J (2009) 1.85
Variation of muscle stiffness with tension during tension transients and constant velocity shortening in the frog. J Physiol (1981) 1.85
Microfilaments in Chaos carolinensis. Membrane association, distribution, and heavy meromyosin binding in the glycerinated cell. J Cell Biol (1973) 1.84
Myosin subfragment-1 attachment to actin. Expected effect on equatorial reflections. Biophys J (1978) 1.80
Organization of actin, myosin, and intermediate filaments in the brush border of intestinal epithelial cells. J Cell Biol (1982) 1.79
Proteins of the kidney microvillus membrane. Identification of subunits after sodium dodecylsullphate/polyacrylamide-gel electrophoresis. Biochem J (1976) 1.75
Determination of the alpha-actinin-binding site on actin filaments by cryoelectron microscopy and image analysis. J Cell Biol (1994) 1.74
Ultrastructure of the Z line of skeletal muscle fibers. J Cell Biol (1971) 1.70
A 13-A map of the actin-scruin filament from the limulus acrosomal process. J Cell Biol (1993) 1.70
Changes of thick filament structure during contraction of frog striated muscle. Biophys J (1981) 1.68
The structure of bacterial ParM filaments. Nat Struct Mol Biol (2007) 1.66
Detection and characterization of actin monomers, oligomers, and filaments in solution by measurement of fluorescence photobleaching recovery. Biophys J (1984) 1.62
The structural basis of muscle contraction. Philos Trans R Soc Lond B Biol Sci (2000) 1.59
Three-dimensional structure of the complex of skeletal muscle actin and bovine pancreatic DNAse I at 6-A resolution. Proc Natl Acad Sci U S A (1981) 1.57
Flash and smash: rapid freezing of muscle fibers activated by photolysis of caged ATP. Biophys J (1993) 1.53
Reconstruction of helical filaments and tubes. Methods Enzymol (2010) 1.51
Direct visualization by electron microscopy of the weakly bound intermediates in the actomyosin adenosine triphosphatase cycle. Biophys J (1993) 1.50
p-NN'-phenylenebismaleimide, a specific cross-linking agent for F-actin. Biochem J (1978) 1.48
Three-dimensional structure of a single filament in the Limulus acrosomal bundle: scruin binds to homologous helix-loop-beta motifs in actin. J Cell Biol (1994) 1.47
Structural basis for the activation of muscle contraction by troponin and tropomyosin. J Mol Biol (2009) 1.42
Crystalline actin sheets: their structure and polymorphism. J Cell Biol (1981) 1.40
Geometrical factors influencing muscle force development. II. Radial forces. Biophys J (1980) 1.40
Ultrastructure of unit fragments of the skeleton of the human erythrocyte membrane. J Cell Biol (1984) 1.31
Crosslinked myosin subfragment 1: a stable analogue of the subfragment-1.ATP complex. Proc Natl Acad Sci U S A (1983) 1.31
New insights into the regulation of the actin cytoskeleton by tropomyosin. Int Rev Cell Mol Biol (2010) 1.28
N-ethylmaleimide-modified heavy meromyosin. A probe for actomyosin interactions. J Cell Biol (1979) 1.27
Polymerization of actin by positively charged liposomes. J Cell Biol (1988) 1.27
Three-dimensional structures of the flagellar dynein-microtubule complex by cryoelectron microscopy. J Cell Biol (2007) 1.27
F-actin is intermolecularly crosslinked by N,N'-p-phenylenedimaleimide through lysine-191 and cysteine-374. Proc Natl Acad Sci U S A (1984) 1.23
Differential staining of actin in metaphase spindles with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin and fluorescent DNase: is actin involved in chromosomal movement? Proc Natl Acad Sci U S A (1981) 1.21
Formation of two-dimensional complexes of F-actin and crosslinking proteins on lipid monolayers: demonstration of unipolar alpha-actinin-F-actin crosslinking. Biophys J (1994) 1.20
Electron cryomicroscopy of acto-myosin-S1 during steady-state ATP hydrolysis. Biophys J (1994) 1.18
Calcium regulation of muscle contraction. Biophys J (1975) 1.13
Studies on the specificity of smooth-muscle antibodies. Clin Exp Immunol (1976) 1.10
Geometrical factors influencing muscle force development. I. The effect of filament spacing upon axial forces. Biophys J (1980) 1.08
Polymorphism of actin paracrystals induced by polylysine. J Cell Biol (1982) 1.06
Three-dimensional reconstruction of thick filaments from Limulus and scorpion muscle. J Cell Biol (1985) 1.02
Structural dynamics of the actomyosin complex probed by a bifunctional spin label that cross-links SH1 and SH2. Biophys J (2008) 1.02
Structure and dynamics of the actin filament. J Mol Biol (2009) 1.01
Crystallization of myosin subfragment 1. Proc Natl Acad Sci U S A (1984) 1.00
Structural studies of synthetic filaments prepared from column-purified myosin. Biophys J (1979) 0.99
The conformation of myosin head domains in rigor muscle determined by X-ray interference. Biophys J (2003) 0.97
The structure of a simple Z line. J Cell Biol (1973) 0.96
Three-dimensional image reconstruction of insect flight muscle. I. The rigor myac layer. J Cell Biol (1989) 0.96
Orientational distribution of spin-labeled actin oriented by flow. Biophys J (1992) 0.96
Real-space processing of helical filaments in SPARX. J Struct Biol (2012) 0.95
Three-dimensional image reconstruction of insect flight muscle. II. The rigor actin layer. J Cell Biol (1989) 0.95
Cryoatomic force microscopy of filamentous actin. Biophys J (2000) 0.95
Unshadowed myosin molecules: STEM mass-maps of myosin heads. EMBO J (1984) 0.94
Structure and orientation of troponin in the thin filament. J Biol Chem (2009) 0.93
Structural transients of contractile proteins upon sudden ATP liberation in skeletal muscle fibers. Biophys J (2004) 0.92
New method for localizing proteins in periodic structures: Fab fragment labeling combined with image processing of electron micrographs. Proc Natl Acad Sci U S A (1977) 0.92
Regular structures in unit membranes. II. Morphological and biochemical characterization of two water-soluble membrane proteins isolated from the suckling rat ileum. J Cell Biol (1976) 0.91
Electron microscopic visualization of the ATPase site of myosin by photoaffinity labeling with a biotinylated photoreactive ADP analog. Proc Natl Acad Sci U S A (1986) 0.89
Theory of muscular contraction extended to groups of actin sites. Proc Natl Acad Sci U S A (1973) 0.89
Patterns in the quinary structures of proteins. Plasticity and inequivalence of individual molecules in helical arrays of sickle cell hemoglobin and tubulin. Biophys J (1980) 0.88
Structure of the myosin head in solution and the effect of light chain 2 removal. Biophys J (1992) 0.88
Bridgelike interconnections between thick filaments in stretched skeletal muscle fibers observed by the freeze-fracture method. J Cell Biol (1986) 0.87
Allele-specific effects of human deafness gamma-actin mutations (DFNA20/26) on the actin/cofilin interaction. J Biol Chem (2009) 0.86
Image reconstruction using electron micrographs of insect flight muscle. Use of thick transverse sections to supplement data from tilted thin longitudinal sections. Biophys J (1986) 0.86
Direct determination of actin polarity in the cell. J Mol Biol (2012) 0.84
A consistent picture of the actin filament related to the orientation of the actin molecule. J Cell Biol (1983) 0.82
A helical processing pipeline for EM structure determination of membrane proteins. Methods (2011) 0.82
Cryo-EM structures of the actin:tropomyosin filament reveal the mechanism for the transition from C- to M-state. J Mol Biol (2013) 0.80
Actin and temperature effects on the cross-linking of the SH1-SH2 helix in myosin subfragment 1. Biophys J (2000) 0.80
The actin-activated ATPase of co-polymer filaments of myosin and myosin-rod. Biochem J (1994) 0.78
Structural changes during muscle contraction. Biochem J (1971) 0.77
Alveolar soft part sarcoma. An elaboration of a three-dimensional configuration of the crystalloids by digital image processing. Am J Pathol (1984) 0.77
A novel approach to the structural analysis of partially decorated actin based filaments. J Struct Biol (2009) 0.77
Electron microscopy and three-dimensional reconstruction of native thin filaments reveal species-specific differences in regulatory strand densities. Biochem Biophys Res Commun (2009) 0.76
Actin Mechanics and Fragmentation. J Biol Chem (2015) 0.76
Possible role of helix-coil transitions in the microscopic mechanism of muscle contraction. Biophys J (1987) 0.76
Optimal orientation in branched cytoskeletal networks. J Math Biol (2010) 0.76
Competition between Tropomyosin, Fimbrin, and ADF/Cofilin drives their sorting to distinct actin filament networks. Elife (2017) 0.76
The Hagfish Gland Thread Cell: A Fiber-Producing Cell Involved in Predator Defense. Cells (2016) 0.75
Oriented thick and thin filaments in Amoeba proteus. J Cell Biol (1975) 0.75
Mechanism of the calcium-regulation of muscle contraction--in pursuit of its structural basis. Proc Jpn Acad Ser B Phys Biol Sci (2015) 0.75
Conservation and divergence between cytoplasmic and muscle-specific actin capping proteins: insights from the crystal structure of cytoplasmic Cap32/34 from Dictyostelium discoideum. BMC Struct Biol (2012) 0.75
Tubular arrays of the actin-DNase I complex induced by gadolinium. Proc Natl Acad Sci U S A (1984) 0.75
Neutrons, magnets, and photons: a career in structural biology. J Biol Chem (2011) 0.75
Hugh E. Huxley: the compleat biophysicist. Biophys J (2014) 0.75
Logical gates in actin monomer. Sci Rep (2017) 0.75
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 28.25
The structural basis of ribosome activity in peptide bond synthesis. Science (2000) 18.82
The mechanism of muscular contraction. Science (1969) 14.47
The low-angle x-ray diagram of vertebrate striated muscle and its behaviour during contraction and rigor. J Mol Biol (1967) 13.91
The kink-turn: a new RNA secondary structure motif. EMBO J (2001) 8.58
RNA tertiary interactions in the large ribosomal subunit: the A-minor motif. Proc Natl Acad Sci U S A (2001) 6.58
X-ray evidence for radial cross-bridge movement and for the sliding filament model in actively contracting skeletal muscle. J Mol Biol (1973) 4.86
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain. Cell (1997) 4.46
Reconstruction of three-dimensional images from electron micrographs of structures with helical symmetry. J Mol Biol (1970) 3.89
The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit. J Mol Biol (2004) 3.73
Isolation, characterization and structure of bacterial flagellar motors containing the switch complex. J Mol Biol (1994) 3.71
Structural difference between resting and rigor muscle; evidence from intensity changes in the lowangle equatorial x-ray diagram. J Mol Biol (1968) 3.70
Structural changes during activation of frog muscle studied by time-resolved X-ray diffraction. J Mol Biol (1986) 3.45
F-actin is a helix with a random variable twist. Nature (1982) 3.32
The crystal structure of yeast phenylalanine tRNA at 1.93 A resolution: a classic structure revisited. RNA (2000) 3.25
Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit. Nature (1999) 3.20
Crossbridge behaviour during muscle contraction. J Muscle Res Cell Motil (1985) 3.20
The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution. EMBO J (1994) 3.18
Muscular contraction and cell motility. Nature (1973) 3.17
Electron microscope observations on actomyosin and actin preparations from Physarum polycephalum, and on their interaction with heavy meromyosin subfragment I from muscle myosin. J Mol Biol (1970) 3.17
Time-resolved X-ray diffraction studies of the myosin layer-line reflections during muscle contraction. J Mol Biol (1982) 3.14
Ribosomal proteins of Escherichia coli. II. Proteins from the 30 s subunit. J Mol Biol (1968) 3.08
Changes in the X-ray reflections from contracting muscle during rapid mechanical transients and their structural implications. J Mol Biol (1983) 2.69
Flagellar hook and hook-associated proteins of Salmonella typhimurium and their relationship to other axial components of the flagellum. J Mol Biol (1990) 2.61
Localization of the Salmonella typhimurium flagellar switch protein FliG to the cytoplasmic M-ring face of the basal body. Proc Natl Acad Sci U S A (1992) 2.57
The geometry of the ribosomal polypeptide exit tunnel. J Mol Biol (2006) 2.53
The bacterial flagellar cap as the rotary promoter of flagellin self-assembly. Science (2000) 2.52
The 3' terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1. Nucleic Acids Res (1979) 2.51
Actin filaments, stereocilia, and hair cells: how cells count and measure. Annu Rev Cell Biol (1992) 2.44
Actin filaments elongate from their membrane-associated ends. J Cell Biol (1981) 2.40
The conformation of the sarcin/ricin loop from 28S ribosomal RNA. Proc Natl Acad Sci U S A (1993) 2.34
How Listeria exploits host cell actin to form its own cytoskeleton. II. Nucleation, actin filament polarity, filament assembly, and evidence for a pointed end capper. J Cell Biol (1992) 2.26
The sarcin/ricin loop, a modular RNA. J Mol Biol (1995) 2.25
Regulation of skeletal muscle contraction. II. Structural studies of the interaction of the tropomyosin-troponin complex with actin. J Mol Biol (1972) 2.17
A 9 A resolution X-ray crystallographic map of the large ribosomal subunit. Cell (1998) 2.14
How actin filaments pack into bundles. Cold Spring Harb Symp Quant Biol (1982) 2.10
Ribosomal proteins of Escherichia coli. I. Demonstration of different primary structures. Proc Natl Acad Sci U S A (1967) 2.03
Three-dimensional structure of the frozen-hydrated flagellar filament. The left-handed filament of Salmonella typhimurium. J Mol Biol (1987) 2.02
Actin in the inner ear: the remarkable structure of the stereocilium. Nature (1980) 1.99
Evidence for cleft closure in actomyosin upon ADP release. Nat Struct Biol (2000) 1.97
Actin filaments, stereocilia, and hair cells of the bird cochlea. II. Packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bent. J Cell Biol (1983) 1.97
Constancy of axial spacings in frog sartorius muscle during contraction. Nature (1965) 1.96
A significant lag in the induction of ovalbumin messenger RNA by steroid hormones: a receptor translocation hypothesis. Cell (1976) 1.89
Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures. Biochemistry (1992) 1.88
The use of synchrotron radiation in time-resolved X-ray diffraction studies of myosin layer-line reflections during muscle contraction. Nature (1980) 1.87
Mass determination and estimation of subunit stoichiometry of the bacterial hook-basal body flagellar complex of Salmonella typhimurium by scanning transmission electron microscopy. Proc Natl Acad Sci U S A (1992) 1.86
Rotational symmetry of the C ring and a mechanism for the flagellar rotary motor. Proc Natl Acad Sci U S A (1999) 1.86
How Listeria exploits host cell actin to form its own cytoskeleton. I. Formation of a tail and how that tail might be involved in movement. J Cell Biol (1992) 1.84
Millisecond time-resolved changes in x-ray reflections from contracting muscle during rapid mechanical transients, recorded using synchrotron radiation. Proc Natl Acad Sci U S A (1981) 1.84
Climate change and the integrity of science. Science (2010) 1.80
Effect of silicon on gastrointestinal absorption of aluminium. Lancet (1993) 1.80
Tetramerization of an RNA oligonucleotide containing a GGGG sequence. Nature (1991) 1.69
The loop E-loop D region of Escherichia coli 5S rRNA: the solution structure reveals an unusual loop that may be important for binding ribosomal proteins. Structure (1997) 1.66
Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies. Clin Ther (2001) 1.65
Actin filaments, stereocilia, and hair cells of the bird cochlea. IV. How the actin filaments become organized in developing stereocilia and in the cuticular plate. Dev Biol (1986) 1.64
Structure of bacterial flagellar filaments at 11 A resolution: packing of the alpha-helices. J Mol Biol (1995) 1.63
Three-dimensional image reconstruction of actin-tropomyosin complex and actin-tropomyosin-troponin T-troponin I complex. J Mol Biol (1975) 1.62
Image reconstruction of the flagellar basal body of Salmonella typhimurium. J Mol Biol (1989) 1.60
The eggshell of insects: differentiation-specific proteins and the control of their synthesis and accumulation during development. Results Probl Cell Differ (1977) 1.56
A neutron scattering study of the distribution of protein and RNA in the 30 S ribosomal subunit of Escherichia coli. J Mol Biol (1975) 1.54
Relapse in chronic depressives on withdrawal of L-tryptophan. Lancet (1990) 1.53
The structural basis of muscular contraction. Proc R Soc Lond B Biol Sci (1971) 1.53
Structures of bacterial flagellar motors from two FliF-FliG gene fusion mutants. J Bacteriol (2001) 1.52
Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis. Acta Psychiatr Scand (2013) 1.52
Bacterial flagellar structure and function. Can J Microbiol (1988) 1.51
Structure of the tubular variants of the head of bacteriophage T4 (polyheads). I. Arrangement of subunits in some classes of polyheads. J Mol Biol (1972) 1.51
The neurocognitive performance of drug-free and medicated euthymic bipolar patients do not differ. Acta Psychiatr Scand (2009) 1.51
Positions of S2, S13, S16, S17, S19 and S21 in the 30 S ribosomal subunit of Escherichia coli. J Mol Biol (1988) 1.50
Structure of F-actin needles from extracts of sea urchin oocytes. J Mol Biol (1981) 1.50
The M2 channel of influenza A virus: a molecular dynamics study. FEBS Lett (1998) 1.49
Ultrastructure of skeletal muscle fibers studied by a plunge quick freezing method: myofilament lengths. Biophys J (1994) 1.49
Flagellar hook structures of Caulobacter and Salmonella and their relationship to filament structure. J Mol Biol (1982) 1.46
Image analysis of helical objects: the Brandeis Helical Package. J Struct Biol (1996) 1.44
Differential requirements for polypeptide chain initiation complex formation at the three bacteriophage R17 initiator regions. Nucleic Acids Res (1977) 1.37
Assignment of NH resonances in nucleic acids using natural abundance 15N-1H correlation spectroscopy with spin-echo and gradient pulses. FEBS Lett (1993) 1.35
Reaction of N-ethyl maleimide with the ribosomes of Escherichia coli. J Mol Biol (1971) 1.34
The variable twist of actin and its modulation by actin-binding proteins. J Cell Biol (1987) 1.33
The conformational properties of elongation factor G and the mechanism of translocation. Biochemistry (1997) 1.32
Positions of proteins S6, S11 and S15 in the 30 S ribosomal subunit of Escherichia coli. J Mol Biol (1981) 1.31
Cross-bridge movement during muscle contraction. Nature (1976) 1.30
Automatic measurement of interference photographs from the ultracentrifuge. Anal Biochem (1972) 1.30
Atomic structures at last: the ribosome in 2000. Curr Opin Struct Biol (2001) 1.28
Calcium-dependent protein binding to phenothiazine columns. J Biol Chem (1982) 1.28
Three-dimensional structure of the complex flagellar filament of Rhizobium lupini and its relation to the structure of the plain filament. J Mol Biol (1987) 1.28
NMR analysis of helix I from the 5S RNA of Escherichia coli. Biochemistry (1992) 1.27
Evidence for a conformational change in actin induced by fimbrin (N375) binding. J Cell Biol (1997) 1.27
Helical disorder and the filament structure of F-actin are elucidated by the angle-layered aggregate. J Mol Biol (1983) 1.27
Molecular dynamics simulation of a synthetic ion channel. Biophys J (1998) 1.26
Changes in the organization of actin filaments in the stereocilia of noise-damaged lizard cochleae. Hear Res (1982) 1.26
Measurement of diffusion constants for nucleic acids by NMR. J Biomol NMR (1997) 1.25
The preparation of deuterated ribosomal materials for neutron scattering. Methods Enzymol (1979) 1.25
Interactions of cytoskeletal elements with the plasma membrane of sarcoma180 ascites tumor cells. Exp Cell Res (1978) 1.25
Exploration of the L18 binding site on 5S RNA by deletion mutagenesis. Nucleic Acids Res (1988) 1.25
X-ray diffraction studies of the structural state of crossbridges in skinned frog sartorius muscle at low ionic strength. J Muscle Res Cell Motil (1987) 1.23
The mechanism of muscular contraction. Sci Am (1965) 1.22
The organization of the Caulobacter crescentus flagellar filament. J Mol Biol (1989) 1.21
Growth conditions control the size and order of actin bundles in vitro. Biophys J (1991) 1.21
Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. J Psychopharmacol (2005) 1.20