Published in Int Ophthalmol Clin on January 01, 2017
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Tear cytokine profiles in dysfunctional tear syndrome. Am J Ophthalmol (2008) 2.37
Desiccating stress induces T cell-mediated Sjögren's Syndrome-like lacrimal keratoconjunctivitis. J Immunol (2006) 2.33
Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res (2006) 2.27
Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. Invest Ophthalmol Vis Sci (2007) 2.09
Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye. Am J Pathol (2005) 1.96
The role of the lacrimal functional unit in the pathophysiology of dry eye. Exp Eye Res (2004) 1.88
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Goblet cell numbers and epithelial proliferation in the conjunctiva of patients with dry eye syndrome treated with cyclosporine. Arch Ophthalmol (2002) 1.81
Expression of Th-1 chemokines and chemokine receptors on the ocular surface of C57BL/6 mice: effects of desiccating stress. Invest Ophthalmol Vis Sci (2007) 1.78
Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome. Invest Ophthalmol Vis Sci (2009) 1.75
A mouse model of keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci (2002) 1.73
Apoptosis of ocular surface cells in experimentally induced dry eye. Invest Ophthalmol Vis Sci (2003) 1.72
Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface. Eye Contact Lens (2005) 1.67
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Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium. Invest Ophthalmol Vis Sci (2006) 1.46
A randomized, double-masked, placebo-controlled, multicenter comparison of loteprednol etabonate ophthalmic suspension, 0.5%, and placebo for treatment of keratoconjunctivitis sicca in patients with delayed tear clearance. Am J Ophthalmol (2004) 1.39
Analysis of topical cyclosporine treatment of patients with dry eye syndrome: effect on conjunctival lymphocytes. Arch Ophthalmol (2000) 1.39
Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca. Cornea (2005) 1.31
Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress. Cornea (2007) 1.31
Effects of sequential artificial tear and cyclosporine emulsion therapy on conjunctival goblet cell density and transforming growth factor-beta2 production. Cornea (2008) 1.27
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Flow cytometric analysis of inflammatory markers in KCS: 6-month treatment with topical cyclosporin A. Invest Ophthalmol Vis Sci (2001) 1.20
Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome. Invest Ophthalmol Vis Sci (2009) 1.20
Tear dysfunction and the cornea: LXVIII Edward Jackson Memorial Lecture. Am J Ophthalmol (2011) 1.18
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Ocular surface APCs are necessary for autoreactive T cell-mediated experimental autoimmune lacrimal keratoconjunctivitis. J Immunol (2011) 1.12
ICAM-1 expression predisposes ocular tissues to immune-based inflammation in dry eye patients and Sjögrens syndrome-like MRL/lpr mice. Exp Eye Res (2004) 1.10
Entrapment of conjunctival goblet cells by desiccation-induced cornification. Invest Ophthalmol Vis Sci (2011) 1.03
The role of apoptosis in the pathogenesis of canine keratoconjunctivitis sicca: the effect of topical Cyclosporin A therapy. Cornea (1998) 1.01
Essential role for c-Jun N-terminal kinase 2 in corneal epithelial response to desiccating stress. Arch Ophthalmol (2009) 0.92
Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye. Exp Eye Res (2013) 0.91
Effect of loteprednol etabonate 0.5% on initiation of dry eye treatment with topical cyclosporine 0.05%. Eye Contact Lens (2014) 0.90
Aqueous Tear Deficiency Increases Conjunctival Interferon-γ (IFN-γ) Expression and Goblet Cell Loss. Invest Ophthalmol Vis Sci (2015) 0.88
Interferon-γ-Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sjögren Syndrome. Am J Pathol (2016) 0.85
Effects of Dry Eye Therapies on Environmentally Induced Ocular Surface Disease. Am J Ophthalmol (2015) 0.84
Long-term Supplementation With n-6 and n-3 PUFAs Improves Moderate-to-Severe Keratoconjunctivitis Sicca: A Randomized Double-Blind Clinical Trial. Cornea (2013) 0.82
Desiccating stress-induced disruption of ocular surface immune tolerance drives dry eye disease. Clin Exp Immunol (2016) 0.77
ICAM-1: its role in the pathophysiology of immune activation in the MRL/LPR mouse. Adv Exp Med Biol (2002) 0.76
Genital human papillomavirus infection in men: incidence and risk factors in a cohort of university students. J Infect Dis (2007) 3.48
Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci (2004) 3.22
Dysfunctional tear syndrome: a Delphi approach to treatment recommendations. Cornea (2006) 3.18
Characterization of putative stem cell phenotype in human limbal epithelia. Stem Cells (2004) 2.73
The incidence and risk factors for developing dry eye after myopic LASIK. Am J Ophthalmol (2006) 2.58
Tear cytokine profiles in dysfunctional tear syndrome. Am J Ophthalmol (2008) 2.37
Desiccating stress induces T cell-mediated Sjögren's Syndrome-like lacrimal keratoconjunctivitis. J Immunol (2006) 2.33
Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res (2006) 2.27
Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. Invest Ophthalmol Vis Sci (2007) 2.09
Phenotypic characterization of human corneal epithelial cells expanded ex vivo from limbal explant and single cell cultures. Exp Eye Res (2004) 2.02
Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells. Invest Ophthalmol Vis Sci (2004) 1.95
ABCG2 transporter identifies a population of clonogenic human limbal epithelial cells. Stem Cells (2005) 1.95
Topical ophthalmic cyclosporine: pharmacology and clinical uses. Surv Ophthalmol (2009) 1.91
The role of the lacrimal functional unit in the pathophysiology of dry eye. Exp Eye Res (2004) 1.88
Dry eye as a mucosal autoimmune disease. Int Rev Immunol (2013) 1.85
Assessing the severity of keratitis sicca with videokeratoscopic indices. Ophthalmology (2003) 1.78
Expression of Th-1 chemokines and chemokine receptors on the ocular surface of C57BL/6 mice: effects of desiccating stress. Invest Ophthalmol Vis Sci (2007) 1.78
JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res (2005) 1.76
Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome. Invest Ophthalmol Vis Sci (2009) 1.75
A mouse model of keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci (2002) 1.73
Apoptosis of ocular surface cells in experimentally induced dry eye. Invest Ophthalmol Vis Sci (2003) 1.72
Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface. Eye Contact Lens (2005) 1.67
Minimal clinically important difference for the ocular surface disease index. Arch Ophthalmol (2010) 1.67
Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline. Invest Ophthalmol Vis Sci (2006) 1.63
Tear cytokine and chemokine analysis and clinical correlations in evaporative-type dry eye disease. Mol Vis (2010) 1.54
Rates and determinants of oral human papillomavirus infection in young men. Sex Transm Dis (2012) 1.48
Recombinant human tumor necrosis factor receptor Fc fusion protein (Etanercept): experience as a therapy for sight-threatening scleritis and sterile corneal ulceration. Eye Contact Lens (2004) 1.46
Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium. Invest Ophthalmol Vis Sci (2006) 1.46
Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomics. J Proteome Res (2009) 1.36
Inflammation in dry eye. Ocul Surf (2004) 1.35
Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells. Stem Cells (2005) 1.34
Doxycycline inhibits TGF-beta1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells. Invest Ophthalmol Vis Sci (2005) 1.33
Sensors of the innate immune system: their mode of action. Nat Rev Rheumatol (2009) 1.31
Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca. Cornea (2005) 1.31
Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress. Cornea (2007) 1.31
Desiccating stress promotion of Th17 differentiation by ocular surface tissues through a dendritic cell-mediated pathway. Invest Ophthalmol Vis Sci (2010) 1.29
Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways. Cornea (2007) 1.29
In vivo confocal microscopy of the ocular surface: from bench to bedside. Curr Eye Res (2013) 1.27
Epithelial-immune cell interaction in dry eye. Cornea (2008) 1.27
Effects of sequential artificial tear and cyclosporine emulsion therapy on conjunctival goblet cell density and transforming growth factor-beta2 production. Cornea (2008) 1.27
Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice. Rheumatology (Oxford) (2009) 1.26
Gap junction protein connexin 43 serves as a negative marker for a stem cell-containing population of human limbal epithelial cells. Stem Cells (2006) 1.23
Corneal epitheliopathy of dry eye induces hyperesthesia to mechanical air jet stimulation. Am J Ophthalmol (2004) 1.20
Regulated expression of collagenases MMP-1, -8, and -13 and stromelysins MMP-3, -10, and -11 by human corneal epithelial cells. Invest Ophthalmol Vis Sci (2003) 1.20
Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci (2003) 1.20
Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome. Invest Ophthalmol Vis Sci (2009) 1.20
Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways. J Allergy Clin Immunol (2011) 1.17
Characterization of a spontaneously immortalized cell line (IOBA-NHC) from normal human conjunctiva. Invest Ophthalmol Vis Sci (2003) 1.16
Phase III safety evaluation of cyclosporine 0.1% ophthalmic emulsion administered twice daily to dry eye disease patients for up to 3 years. Ophthalmology (2005) 1.15
Therapy of progressive rheumatoid arthritis-associated corneal ulceration with infliximab. Cornea (2005) 1.15
Cytokine and chemokine levels in tears from healthy subjects. Acta Ophthalmol (2010) 1.14
Anterior segment optical coherence tomography: a diagnostic instrument for conjunctivochalasis. Am J Ophthalmol (2010) 1.13
TGF-beta1 stimulates production of gelatinase (MMP-9), collagenases (MMP-1, -13) and stromelysins (MMP-3, -10, -11) by human corneal epithelial cells. Exp Eye Res (2004) 1.12
TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium. Int J Biochem Cell Biol (2011) 1.12
Ocular surface APCs are necessary for autoreactive T cell-mediated experimental autoimmune lacrimal keratoconjunctivitis. J Immunol (2011) 1.12
Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK. Invest Ophthalmol Vis Sci (2008) 1.12
Expression and regulation of cornified envelope proteins in human corneal epithelium. Invest Ophthalmol Vis Sci (2006) 1.11
Patterned expression of neurotrophic factors and receptors in human limbal and corneal regions. Mol Vis (2007) 1.11
ICAM-1 expression predisposes ocular tissues to immune-based inflammation in dry eye patients and Sjögrens syndrome-like MRL/lpr mice. Exp Eye Res (2004) 1.10
Nerve growth factor and its receptor TrkA serve as potential markers for human corneal epithelial progenitor cells. Exp Eye Res (2007) 1.09
Partial enrichment of a population of human limbal epithelial cells with putative stem cell properties based on collagen type IV adhesiveness. Exp Eye Res (2005) 1.09
Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells. Cornea (2008) 1.08
Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines. Invest Ophthalmol Vis Sci (2009) 1.08
Interferon-γ exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways. Invest Ophthalmol Vis Sci (2011) 1.08
Infectious keratitis after laser in situ keratomileusis: results of an ASCRS survey. J Cataract Refract Surg (2003) 1.07
Desiccating stress induces CD4+ T-cell-mediated Sjögren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-γ. Am J Pathol (2011) 1.07
Is autologous serum a tonic for the ailing corneal epithelium? Am J Ophthalmol (2006) 1.05
Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye. Cornea (2008) 1.02
NK cells promote Th-17 mediated corneal barrier disruption in dry eye. PLoS One (2012) 1.02
Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye. Cornea (2012) 1.02
Induction of Th17 differentiation by corneal epithelial-derived cytokines. J Cell Physiol (2010) 1.01
Increasing prevalence and severity of conjunctivochalasis with aging detected by anterior segment optical coherence tomography. Am J Ophthalmol (2012) 1.00
Sensors of the innate immune system: their link to rheumatic diseases. Nat Rev Rheumatol (2010) 1.00
Effect of experimental dry eye on tear sodium concentration in the mouse. Eye Contact Lens (2005) 0.98
Suppressive effects of azithromycin on zymosan-induced production of proinflammatory mediators by human corneal epithelial cells. Invest Ophthalmol Vis Sci (2010) 0.98
Desiccating environmental stress exacerbates autoimmune lacrimal keratoconjunctivitis in non-obese diabetic mice. J Autoimmun (2007) 0.97
The impact of the Boston ocular surface prosthesis on wavefront higher-order aberrations. Am J Ophthalmol (2011) 0.97
Multicenter open-label study evaluating the efficacy of azithromycin ophthalmic solution 1% on the signs and symptoms of subjects with blepharitis. Cornea (2010) 0.97
Bilateral acanthamoeba keratitis. Am J Ophthalmol (2008) 0.97
Infectious keratitis after LASIK. Ophthalmology (2003) 0.97
Noninvasive assessment of tear stability with the tear stability analysis system in tear dysfunction patients. Invest Ophthalmol Vis Sci (2011) 0.96
Experimentally induced dry eye produces ocular surface inflammation and epithelial disease. Adv Exp Med Biol (2002) 0.96
TSLP and downstream molecules in experimental mouse allergic conjunctivitis. Invest Ophthalmol Vis Sci (2010) 0.96
Matrix metalloproteinases in corneal inflammation. Ocul Surf (2005) 0.95
Post-LASIK tear dysfunction and dysesthesia. Ocul Surf (2010) 0.95