Published in Sci Rep on March 13, 2017
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol (1993) 38.03
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform (2012) 23.58
The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J Gen Virol (1988) 19.25
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial. Lancet (2008) 9.17
Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants. J Virol (1977) 5.98
Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial. Lancet (2010) 4.23
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature (2005) 2.87
Epidemiology, clinical presentation, and antibody response to primary infection with herpes simplex virus type 1 and type 2 in young women. Clin Infect Dis (2012) 2.55
Helicase-primase inhibitor pritelivir for HSV-2 infection. N Engl J Med (2014) 2.36
Biological characterization of a herpes simplex virus intertypic recombinant which is completely and specifically non-neurovirulent. Virology (1983) 2.32
RDP4: Detection and analysis of recombination patterns in virus genomes. Virus Evol (2015) 2.23
Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene. Cell Host Microbe (2009) 1.90
Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA (2011) 1.85
Antigenic specificities of human CD4+ T-cell clones recovered from recurrent genital herpes simplex virus type 2 lesions. J Virol (1994) 1.83
Seroprevalence of herpes simplex virus types 1 and 2--United States, 1999-2010. J Infect Dis (2013) 1.80
Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations. J Virol (2010) 1.71
A wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses. PLoS Pathog (2011) 1.63
The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway. J Virol (2002) 1.54
The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region. J Exp Med (1996) 1.41
Genetic and biological analyses of a herpes simplex virus intertypic recombinant reduced specifically for neurovirulence. J Virol (1987) 1.40
Evolution and diversity in human herpes simplex virus genomes. J Virol (2013) 1.35
Herpes simplex virus suppresses necroptosis in human cells. Cell Host Microbe (2015) 1.32
Divergence and recombination of clinical herpes simplex virus type 2 isolates. J Virol (2007) 1.16
Attenuated vaccines can recombine to form virulent field viruses. Science (2012) 1.15
Herpes simplex virus latency-associated transcript sequence downstream of the promoter influences type-specific reactivation and viral neurotropism. J Virol (2007) 1.15
Recurrent benign lymphocytic meningitis. Clin Infect Dis (2006) 1.14
Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees. Science (2014) 1.13
Out-of-Africa, the peopling of continents and islands: tracing uniparental gene trees across the map. Philos Trans R Soc Lond B Biol Sci (2012) 1.11
Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection. Virology (2001) 1.09
Difference in incidence of spontaneous mutations between Herpes simplex virus types 1 and 2. Antimicrob Agents Chemother (2000) 1.09
Evidence for differences in immunologic and pathogenesis properties of herpes simplex virus 2 strains from the United States and South Africa. J Infect Dis (2011) 1.02
A genome-wide comparative evolutionary analysis of herpes simplex virus type 1 and varicella zoster virus. PLoS One (2011) 1.01
Oncolytic viruses: From bench to bedside with a focus on safety. Hum Vaccin Immunother (2015) 1.01
Disruption of the U(L)41 gene in the herpes simplex virus 2 dl5-29 mutant increases its immunogenicity and protective capacity in a murine model of genital herpes. Virology (2007) 1.00
Amplification of reiterated sequences of herpes simplex virus type 1 (HSV-1) genome to discriminate between clinical HSV-1 isolates. J Clin Microbiol (1999) 1.00
Evolutionary origins of human herpes simplex viruses 1 and 2. Mol Biol Evol (2014) 0.99
Genome Sequencing and Analysis of Geographically Diverse Clinical Isolates of Herpes Simplex Virus 2. J Virol (2015) 0.98
A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Mol Ther (2014) 0.97
Recombination of Globally Circulating Varicella-Zoster Virus. J Virol (2015) 0.94
Importance of herpes simplex virus type-1 (HSV-1) in primary genital herpes. Acta Derm Venereol (2006) 0.92
Mapping of the thymidine kinase genes of type 1 and type 2 herpes simplex viruses using intertypic recombinants. J Gen Virol (1980) 0.92
Natural recombinant between equine herpesviruses 1 and 4 in the ICP4 gene. Microbiol Immunol (2005) 0.91
Genomic sequences of a low passage herpes simplex virus 2 clinical isolate and its plaque-purified derivative strain. Virology (2013) 0.89
Genome sequence of a chimpanzee herpesvirus and its relation to other primate alphaherpesviruses. Arch Virol (2013) 0.87
Genomic, phylogenetic, and recombinational characterization of herpes simplex virus 2 strains. J Virol (2015) 0.87
The double-edged sword: How evolution can make or break a live-attenuated virus vaccine. Evolution (N Y) (2011) 0.86
Detection of a new variant of herpes simplex virus type 2 among HIV-1-infected individuals. J Clin Virol (2013) 0.85
Recombination Analysis of Herpes Simplex Virus 1 Reveals a Bias toward GC Content and the Inverted Repeat Regions. J Virol (2015) 0.82
Gene polymorphism of thymidine kinase and DNA polymerase in clinical strains of herpes simplex virus. Antivir Ther (2011) 0.82
Experimental in vivo generation of intertypic recombinant strains of HSV in the mouse. Arch Virol (1992) 0.81
Genetic Diversity within Alphaherpesviruses: Characterization of a Novel Variant of Herpes Simplex Virus 2. J Virol (2015) 0.79
Enzymatically produced pools of canonical and Dicer-substrate siRNA molecules display comparable gene silencing and antiviral activities against herpes simplex virus. PLoS One (2012) 0.78
Inhibition of clinical pathogenic herpes simplex virus 1 strains with enzymatically created siRNA pools. J Med Virol (2016) 0.77
Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes. Antiviral Res (2007) 0.77
Analysis of unselected HSV-1 McKrae/HSV-2 HG 52 recombinants demonstrates preferential recombination between intact genomes and restriction endonuclease fragments containing an origin of replication. Arch Virol (1989) 0.76
Genotyping of herpes simplex virus type 1 by whole-genome sequencing. J Gen Virol (2016) 0.76
Lack of evidence for intertypic recombinants in the pathogenesis of recurrent genital infections with herpes simplex virus type 1. Sex Transm Dis (1986) 0.76
Diversity in the acute CD8 T cell response to vaccinia virus in humans. J Immunol (2005) 1.16
Development of multiplexed real-time quantitative polymerase chain reaction assay for detecting human adenoviruses. Diagn Microbiol Infect Dis (2008) 0.84