| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism.
|
Biochemistry
|
2000
|
2.37
|
|
2
|
The Alzheimer's peptide a beta adopts a collapsed coil structure in water.
|
J Struct Biol
|
2000
|
2.26
|
|
3
|
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation.
|
Science
|
1995
|
2.12
|
|
4
|
Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease.
|
Proc Natl Acad Sci U S A
|
1988
|
1.87
|
|
5
|
Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion.
|
Am J Physiol
|
1993
|
1.77
|
|
6
|
Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo.
|
J Neurosci
|
1998
|
1.68
|
|
7
|
Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma.
|
J Biol Chem
|
1996
|
1.61
|
|
8
|
Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.
|
Proc Natl Acad Sci U S A
|
1995
|
1.60
|
|
9
|
Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence.
|
Biochemistry
|
1996
|
1.58
|
|
10
|
Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.
|
Biochemistry
|
1998
|
1.54
|
|
11
|
A beta deposition inhibitor screen using synthetic amyloid.
|
Nat Biotechnol
|
1997
|
1.37
|
|
12
|
Novel peptide fragments originating from PGLa and the caerulein and xenopsin precursors from Xenopus laevis.
|
J Biol Chem
|
1986
|
1.30
|
|
13
|
Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues.
|
J Neurosci
|
1989
|
1.27
|
|
14
|
Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations.
|
Biochemistry
|
1999
|
1.27
|
|
15
|
Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid.
|
J Struct Biol
|
2000
|
1.20
|
|
16
|
In vitro growth of Alzheimer's disease beta-amyloid plaques displays first-order kinetics.
|
Biochemistry
|
1996
|
1.19
|
|
17
|
Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.
|
J Neurochem
|
1993
|
1.19
|
|
18
|
Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors.
|
Proc Natl Acad Sci U S A
|
1994
|
1.19
|
|
19
|
Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis.
|
J Comp Neurol
|
1995
|
1.19
|
|
20
|
Substance P receptor binding sites are expressed by glia in vivo after neuronal injury.
|
Proc Natl Acad Sci U S A
|
1989
|
1.15
|
|
21
|
Photoaffinity cross-linking of Alzheimer's disease amyloid fibrils reveals interstrand contact regions between assembled beta-amyloid peptide subunits.
|
Biochemistry
|
2001
|
1.14
|
|
22
|
Intestinal absorption and excretion of octapeptides composed of D amino acids.
|
Proc Natl Acad Sci U S A
|
1994
|
1.08
|
|
23
|
Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis.
|
Gastroenterology
|
1995
|
1.06
|
|
24
|
Pharmacological analysis of [3H]-senktide binding to NK3 tachykinin receptors in guinea-pig ileum longitudinal muscle-myenteric plexus and cerebral cortex membranes.
|
Br J Pharmacol
|
1990
|
1.02
|
|
25
|
Intra-arterial infusion of [125I]A beta 1-40 labels amyloid deposits in the aged primate brain in vivo.
|
Neuroreport
|
1996
|
1.01
|
|
26
|
Receptors for sensory neuropeptides in human inflammatory diseases: implications for the effector role of sensory neurons.
|
Peptides
|
1989
|
0.99
|
|
27
|
Delayed behavioral effects following intrahippocampal injection of aggregated A beta (1-42).
|
Brain Res
|
1999
|
0.98
|
|
28
|
Absorption and excretion of undegradable peptides: role of lipid solubility and net charge.
|
J Pharmacol Exp Ther
|
1997
|
0.96
|
|
29
|
Receptor binding sites for substance P and substance K in the canine gastrointestinal tract and their possible role in inflammatory bowel disease.
|
Neuroscience
|
1988
|
0.93
|
|
30
|
Substance P receptors: localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand.
|
Brain Res
|
1984
|
0.92
|
|
31
|
Increased substance P receptor expression by blood vessels and lymphoid aggregates in Clostridium difficile-induced pseudomembranous colitis.
|
Dig Dis Sci
|
1996
|
0.91
|
|
32
|
Regional distribution of kassinin-like immunoreactivity in rat central and peripheral tissues and the effect of capsaicin.
|
Brain Res
|
1984
|
0.91
|
|
33
|
The autoradiographic distribution of kassinin and substance K binding sites is different from the distribution of substance P binding sites in rat brain.
|
Eur J Pharmacol
|
1984
|
0.90
|
|
34
|
Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo.
|
Brain Res
|
1996
|
0.90
|
|
35
|
Mapping peptide-binding domains of the substance P (NK-1) receptor from P388D1 cells with photolabile agonists.
|
J Biol Chem
|
1995
|
0.88
|
|
36
|
A study of tachykinin-immunoreactive neurons in monkey cerebral cortex.
|
J Neurosci
|
1988
|
0.87
|
|
37
|
Substance P and substance K receptor binding sites in the human gastrointestinal tract: localization by autoradiography.
|
Peptides
|
1989
|
0.87
|
|
38
|
Beta 2-adrenergic receptors are expressed by glia in vivo in the normal and injured central nervous system in the rat, rabbit, and human.
|
J Neurosci
|
1995
|
0.87
|
|
39
|
The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes.
|
Peptides
|
1988
|
0.87
|
|
40
|
Stereochemical specificity of Alzheimer's disease beta-peptide assembly.
|
Biopolymers
|
1999
|
0.86
|
|
41
|
Zinc-induced aggregation of human and rat beta-amyloid peptides in vitro.
|
J Neurochem
|
1996
|
0.86
|
|
42
|
A novel radioimmunoassay for neuromedin K. I. Absence of neuromedin K-like immunoreactivity in guinea pig ileum and urinary bladder. II. Heterogeneity of tachykinins in guinea pig tissues.
|
Regul Pept
|
1989
|
0.85
|
|
43
|
Receptor binding sites for cholecystokinin, galanin, somatostatin, substance P and vasoactive intestinal polypeptide in sympathetic ganglia.
|
Neuroscience
|
1992
|
0.85
|
|
44
|
Pharmacological characterisation of a novel tachykinin isolated from mammalian spinal cord.
|
Eur J Pharmacol
|
1984
|
0.84
|
|
45
|
Local anesthetics inhibit substance P binding and evoked increases in intracellular Ca2+.
|
Anesthesiology
|
1995
|
0.84
|
|
46
|
Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors.
|
Neurosci Lett
|
1994
|
0.82
|
|
47
|
Evidence for vasoactive intestinal polypeptide as a neurotransmitter in smooth muscle of the urogenital tract.
|
Brain Res
|
1984
|
0.82
|
|
48
|
Agonist-induced photoincorporation of a p-benzoylphenylalanine derivative of substance P into membrane-spanning region 2 of the Torpedo nicotinic acetylcholine receptor delta subunit.
|
Mol Pharmacol
|
1994
|
0.82
|
|
49
|
Expression of endothelin-B receptors by glia in vivo is increased after CNS injury in rats, rabbits, and humans.
|
Exp Neurol
|
1997
|
0.81
|
|
50
|
Structure of a mycobacterial polysaccharide-fatty acyl-CoA complex: nuclear magnetic resonance studies.
|
Proc Natl Acad Sci U S A
|
1980
|
0.81
|
|
51
|
Neuropeptide Y/peptide YY receptor binding sites in the heart: localization and pharmacological characterization.
|
Neuroscience
|
1993
|
0.81
|
|
52
|
Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin.
|
Brain Res
|
1986
|
0.80
|
|
53
|
Substance K and substance P in the ventral tegmental area.
|
Neurosci Lett
|
1985
|
0.80
|
|
54
|
Substance K and substance P differentially modulate mesolimbic and mesocortical systems.
|
Peptides
|
1985
|
0.80
|
|
55
|
Deposition of soluble amyloid-beta onto amyloid templates: with application for the identification of amyloid fibril extension inhibitors.
|
Methods Enzymol
|
1999
|
0.80
|
|
56
|
"Kassinin" in mammals: the newest tachykinins.
|
Peptides
|
1985
|
0.79
|
|
57
|
A pharmacological study with substance K: evidence for multiple types of tachykinin receptors.
|
Eur J Pharmacol
|
1984
|
0.78
|
|
58
|
Zinc and Alzheimer's disease.
|
Science
|
1995
|
0.77
|
|
59
|
Substance P receptors on canine chief cells: localization, characterization, and function.
|
J Neurosci
|
1989
|
0.77
|
|
60
|
New insights into the neuropathology and cell biology of Alzheimer's disease.
|
Geriatrics
|
1997
|
0.77
|
|
61
|
Alterations in receptors for sensory neuropeptides in human inflammatory bowel disease.
|
Adv Exp Med Biol
|
1991
|
0.77
|
|
62
|
Immunocytochemical localization of neuromedin K (neurokinin B) in rat spinal ganglia and cord.
|
Peptides
|
1991
|
0.77
|
|
63
|
Heterogeneity of tachykinin-like immunoreactive peptides in rat spinal cord and dorsal root ganglia.
|
Peptides
|
1989
|
0.76
|
|
64
|
p-(4-Hydroxybenzoyl)phenylalanine: a photoreactive amino acid analog amenable to radioiodination for elucidation of peptide-protein interaction. Application to substance P receptor.
|
Biochemistry
|
1997
|
0.75
|
|
65
|
The localization and characterization of substance P and substance K in striatonigral neurons.
|
Brain Res
|
1986
|
0.75
|
|
66
|
Development of a novel probe for measuring drug binding to the F1*S variant of human alpha 1-acid glycoprotein.
|
J Pharm Sci
|
2001
|
0.75
|
|
67
|
The regional distribution of kassinin-like immunoreactivity in central and peripheral tissues of the cat.
|
Brain Res
|
1985
|
0.75
|
|
68
|
Simultaneous extraction of total RNA and peptides from tissues: application to tachykinins.
|
Peptides
|
1995
|
0.75
|