Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response.

MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol (2011) 220.97

Clustal W and Clustal X version 2.0. Bioinformatics (2007) 126.47

T antigen is bound to a host protein in SV40-transformed cells. Nature (1979) 17.78

Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell (1979) 14.05

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell (1992) 7.06

p53 isoforms can regulate p53 transcriptional activity. Genes Dev (2005) 6.76

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature (2003) 4.80

The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J (2002) 4.63

Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol (1999) 3.40

Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response. Proc Natl Acad Sci U S A (2001) 3.29

Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest. J Virol (1995) 3.18

Host defense, viruses and apoptosis. Cell Death Differ (2001) 2.84

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development. Cancer Res (2003) 2.46

p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene (2001) 2.40

Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene (1995) 2.00

Comparative binding of p53 to its promoter and DNA recognition elements. J Mol Biol (2005) 1.96

p53 is a suppressor of inflammatory response in mice. FASEB J (2005) 1.91

Apoptosis: an innate immune response to virus infection. Trends Microbiol (1999) 1.82

The isoforms of the p53 protein. Cold Spring Harb Perspect Biol (2010) 1.76

Transcriptional role of p53 in interferon-mediated antiviral immunity. J Exp Med (2008) 1.72

TP53 family members and human cancers. Hum Mutat (2003) 1.70

Transcription-independent p53 apoptosis: an alternative route to death. Trends Cell Biol (2009) 1.68

DeltaNp73beta is active in transactivation and growth suppression. Mol Cell Biol (2004) 1.56

p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300. Cancer Res (1998) 1.51

CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling. J Biol Chem (1999) 1.47

Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication. J Virol (2005) 1.47

Cross talk between PML and p53 during poliovirus infection: implications for antiviral defense. J Virol (2006) 1.30

Microarray and RT-PCR screening for white spot syndrome virus immediate-early genes in cycloheximide-treated shrimp. Virology (2005) 1.29

Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets. Nucleic Acids Res (2007) 1.22

p300/CBP-dependent and -independent transcriptional interference between NF-kappaB RelA and p53. Biochem Biophys Res Commun (2000) 1.17

Analysis of Litopenaeus vannamei transcriptome using the next-generation DNA sequencing technique. PLoS One (2012) 1.16

Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses. Proc Natl Acad Sci U S A (2012) 1.11

Activation of p53 tumor suppressor by hepatitis C virus core protein. Virology (1999) 1.08

p53 inhibits JC virus DNA replication in vivo and interacts with JC virus large T-antigen. Virology (1996) 1.04

Roles of p53 in herpes simplex virus 1 replication. J Virol (2013) 0.98

Identification of the immediate-early genes of white spot syndrome virus. Virology (2009) 0.98

Identification and functional study of a shrimp Dorsal homologue. Dev Comp Immunol (2009) 0.94

Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei. PLoS One (2012) 0.86

Identification and functional study of a shrimp Relish homologue. Fish Shellfish Immunol (2009) 0.84

Identification of three immediate-early genes of white spot syndrome virus. Arch Virol (2011) 0.83

Identification, characterization, and function analysis of the Cactus gene from Litopenaeus vannamei. PLoS One (2012) 0.83

Pellino protein from pacific white shrimp Litopenaeus vannamei positively regulates NF-κB activation. Dev Comp Immunol (2014) 0.78

Presence of Tube isoforms in Litopenaeus vannamei suggests various regulatory patterns of signal transduction in invertebrate NF-κB pathway. Dev Comp Immunol (2013) 0.78

p53 is involved in shrimp survival via its regulation roles on MnSOD and GPx in response to acute environmental stresses. Comp Biochem Physiol C Toxicol Pharmacol (2013) 0.78

Litopenaeus vannamei NF-κB is required for WSSV replication. Dev Comp Immunol (2014) 0.77

A C-type lectin (LvCTL4) from Litopenaeus vannamei is a downstream molecule of the NF-κB signaling pathway and participates in antibacterial immune response. Fish Shellfish Immunol (2015) 0.77

p53 Is a Host Cell Regulator during Herpes Simplex Encephalitis. J Virol (2016) 0.77

MKK6 from pacific white shrimp Litopenaeus vannamei is responsive to bacterial and WSSV infection. Mol Immunol (2015) 0.76

A MicroRNA-Mediated Positive Feedback Regulatory Loop of the NF-κB Pathway in Litopenaeus vannamei. J Immunol (2016) 0.76

Hypoxia drives apoptosis independently of p53 and metallothionein transcript levels in hemocytes of the whiteleg shrimp Litopenaeus vannamei. Chemosphere (2016) 0.76