Lipidomic Signature of Progression of Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28451650)

Published in KI Rep on August 18, 2016

Authors

Farsad Afshinnia1, Thekkelnaycke M Rajendiran2,3, Alla Karnovsky4,3, Tanu Soni3, Xue Wang5, Dawei Xie5, Wei Yang5, Tariq Shafi6, Matthew R Weir7, Jiang He8, Carolyn S Brecklin9, Eugene P Rhee10, Jeffrey R Schelling11, Akinlolu Ojo1, Harold Feldman5, George Michailidis12, Subramaniam Pennathur1,4,3

Author Affiliations

1: Division of Nephrology Department of Internal Medicine, University of Michigan.
2: Department of Pathology, University of Michigan.
3: Michigan Regional Comprehensive Metabolomics Resource Core.
4: Department of Computational Medicine & Bioinformatics, University of Michigan.
5: Department of Biostatistics and Epidemiology, University of Pennsylvania.
6: Johns Hopkins University School of Medicine.
7: Division of Nephrology, Department of Medicine, University of Maryland School of Medicine.
8: Tulane University School of Medicine.
9: University of Illinois at Chicago.
10: Massachusetts General Hospital.
11: Case Western Reserve University, MetroHealth Medical Center.
12: Department of Statistics, University of Michigan.

Articles cited by this

Statistical significance for genomewide studies. Proc Natl Acad Sci U S A (2003) 88.64

A new equation to estimate glomerular filtration rate. Ann Intern Med (2009) 71.41

Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics (1988) 70.41

A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology (1983) 30.77

Controlling the false discovery rate in behavior genetics research. Behav Brain Res (2001) 21.82

Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med (2004) 11.52

The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods. J Am Soc Nephrol (2003) 7.79

Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation (2011) 6.36

Random forest: a classification and regression tool for compound classification and QSAR modeling. J Chem Inf Comput Sci (2003) 5.93

MetaboAnalyst: a web server for metabolomic data analysis and interpretation. Nucleic Acids Res (2009) 5.70

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis. Nucleic Acids Res (2012) 5.68

Chronic Renal Insufficiency Cohort (CRIC) Study: baseline characteristics and associations with kidney function. Clin J Am Soc Nephrol (2009) 4.16

Update of the LIPID MAPS comprehensive classification system for lipids. J Lipid Res (2008) 4.01

Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans. J Clin Invest (2011) 3.23

Signalling mechanisms regulating lipolysis. Cell Signal (2005) 2.32

Sample size determination for diagnostic accuracy studies involving binormal ROC curve indices. Stat Med (1997) 2.08

Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm). Anal Bioanal Chem (2004) 1.88

Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data. Bioinformatics (2011) 1.69

Lipoprotein abnormalities are associated with increased rate of progression of human chronic renal insufficiency. Nephrol Dial Transplant (1997) 1.33

Compensation for systematic cross-contribution improves normalization of mass spectrometry based metabolomics data. Anal Chem (2009) 1.25

Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics. PLoS One (2012) 1.21

Bioinformatics and systems biology of the lipidome. Chem Rev (2011) 1.14

Relation of serum lipids and lipoproteins with progression of CKD: The CRIC study. Clin J Am Soc Nephrol (2014) 1.10

Lipoprotein abnormalities associated with mild impairment of kidney function in the multi-ethnic study of atherosclerosis. Clin J Am Soc Nephrol (2007) 1.07

Importance of phosphatidylethanolamine for association of protein kinase C and other cytoplasmic proteins with membranes. Biochemistry (1992) 1.06

The effect of n-3 long-chain polyunsaturated fatty acid supplementation on urine protein excretion and kidney function: meta-analysis of clinical trials. Am J Clin Nutr (2009) 1.04

Changes in diacylglycerol labeling, cell shape, and protein phosphorylation distinguish "triggering" from "activation" of human neutrophils. J Biol Chem (1988) 1.03

Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro. Oncogene (2004) 1.03

Hyperlipidemia and long-term outcomes in nondiabetic chronic kidney disease. Clin J Am Soc Nephrol (2010) 1.01

Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-zeta. Biochem J (1997) 1.01

Megavariate analysis of hierarchical QSAR data. J Comput Aided Mol Des (2002) 1.00

Serum triglycerides are a predictive factor for the development and the progression of renal and retinal complications in patients with type 1 diabetes. Diabetes Metab (2004) 0.97

p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy. J Biol Chem (2012) 0.96

Lipid and lipoprotein metabolism in chronic kidney disease. J Ren Nutr (2009) 0.92

Metabolomics and diabetes: analytical and computational approaches. Diabetes (2015) 0.90

Involvement of diacylglycerol production in activation of nuclear factor kappaB by a CD14-mediated lipopolysaccharide stimulus. Biochem J (1997) 0.88

Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes. Diabetes (2012) 0.88

Lipidomics: quest for molecular lipid biomarkers in cardiovascular disease. Circ Cardiovasc Genet (2014) 0.86

The effects of n-3 long-chain polyunsaturated fatty acid supplementation on biomarkers of kidney injury in adults with diabetes: results of the GO-FISH trial. Diabetes Care (2012) 0.86

Phosphatidylethanolamine N-methyltransferase 2 and CTP-phosphocholine cytidylyltransferase expressions are related with protein kinase C isozymes in developmental liver growth. Biochem Biophys Res Commun (1996) 0.86

Anti-inflammatory action of a phosphatidylcholine, phosphatidylethanolamine and N-acylphosphatidylethanolamine-enriched diet in carrageenan-induced pleurisy. Eur Surg Res (2008) 0.83

The long-term combined stimulatory effects of ethanol and phorbol ester on phosphatidylethanolamine hydrolysis are mediated by a phospholipase C and prevented by overexpressed alpha-protein kinase C in fibroblasts. Eur J Biochem (1992) 0.83

Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease. J Lipid Res (2014) 0.82

Critical role of diacylglycerol- and phospholipid-regulated protein kinase C epsilon in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol. Mol Cell Biol (2002) 0.82

Expression of protein kinase C-beta promotes the stimulatory effect of phorbol ester on phosphatidylethanolamine synthesis. Arch Biochem Biophys (1997) 0.80

Cooperative effects of ethanol and protein kinase C activators on phospholipase-D-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 fibroblasts. Biochim Biophys Acta (1992) 0.79

Diacylglycerol kinase (DGK) inhibitor II (R59949) could suppress retinal neovascularization and protect retinal astrocytes in an oxygen-induced retinopathy model. J Mol Neurosci (2014) 0.79

Vitamin K3 preferentially inhibits stimulation of phospholipase D-mediated hydrolysis of phosphatidylethanolamine by protein kinase C activators in NIH 3T3 fibroblasts. Arch Biochem Biophys (1994) 0.76

Involvement of phospholipase D and protein kinase C in phorbol ester and fatty acid stimulated turnover of phosphatidylcholine and phosphatidylethanolamine in neural cells. Biochim Biophys Acta (1998) 0.76

Age-related changes in the activation of aortic cholesteryl ester hydrolases by protein kinases in rats. Biochim Biophys Acta (1998) 0.76