Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.

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🔗 View Article (PMID 28475900)

Published in Cell on May 04, 2017

Authors

Yonit Lavin1, Soma Kobayashi1, Andrew Leader1, El-Ad David Amir2, Naama Elefant3, Camille Bigenwald1, Romain Remark1, Robert Sweeney4, Christian D Becker5, Jacob H Levine6, Klaus Meinhof5, Andrew Chow1, Seunghee Kim-Shulze2, Andrea Wolf7, Chiara Medaglia3, Hanjie Li3, Julie A Rytlewski8, Ryan O Emerson8, Alexander Solovyov9, Benjamin D Greenbaum9, Catherine Sanders8, Marissa Vignali8, Mary Beth Beasley10, Raja Flores7, Sacha Gnjatic11, Dana Pe'er6, Adeeb Rahman12, Ido Amit3, Miriam Merad13

Author Affiliations

1: Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
2: The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
3: Department of Immunology, Weizmann Institute, Rehovot 76100, Israel.
4: Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
5: Division of Pulmonology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
6: Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065, USA.
7: Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
8: Adaptive Biotechnologies Inc., Seattle, WA 98102, USA.
9: Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Division of Hematology/Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
10: Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
11: The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Division of Hematology/Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
12: The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
13: Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: miriam.merad@mssm.edu.