Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women.

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Published in PLoS One on May 11, 2017

Authors

Peter B Gilbert1,2, Jean-Louis Excler3,4, Georgia D Tomaras5, Lindsay N Carpp1, Barton F Haynes5, Hua-Xin Liao5, David C Montefiori6, Supachai Rerks-Ngarm7, Punnee Pitisuttithum8, Sorachai Nitayaphan9, Jaranit Kaewkungwal10, Gustavo H Kijak4,3, Sodsai Tovanabutra4,3, Donald P Francis11, Carter Lee11, Faruk Sinangil11, Phillip W Berman12, Nakorn Premsri7, Prayura Kunasol7, Robert J O'Connell13, Nelson L Michael3, Merlin L Robb3, Rhoda Morrow14,15, Lawrence Corey15,16, Jerome H Kim3

Author Affiliations

1: Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
2: Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
3: US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
4: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America.
5: Duke University Human Vaccine Institute and the Center for HIV/AIDS Vaccine Immunology, Duke University School of Medicine, Durham, North Carolina, United States of America.
6: Duke University Medical Center, Durham, North Carolina, United States of America.
7: Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
8: Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
9: Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
10: Center of Excellence for Biomedical and Public Health Informatics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
11: Global Solutions for Infectious Diseases, South San Francisco, California, United States of America.
12: Department of Biomolecular Engineering, Baskin School of Engineering, University of California, Santa Cruz, California, United States of America.
13: Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
14: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
15: Department of Laboratory Medicine, University of Washington, Seattle, Washington, United States of America.
16: HIV Vaccine Trials Network, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

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