Published in Sci Rep on May 15, 2017
Cancer statistics, 2015. CA Cancer J Clin (2015) 57.51
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol (1997) 29.02
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med (2011) 24.32
FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene (2005) 7.50
Efficacy and safety of vismodegib in advanced basal-cell carcinoma. N Engl J Med (2012) 6.90
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science (2003) 4.32
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol (2010) 4.22
A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell (2008) 3.94
Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents. Pharmacol Ther (2005) 3.27
TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia. Nature (2010) 3.12
A receptor for green tea polyphenol EGCG. Nat Struct Mol Biol (2004) 2.46
Can we safely target the WNT pathway? Nat Rev Drug Discov (2014) 2.31
DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer. Gastroenterology (2013) 2.26
cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology. Circ Res (2007) 1.80
Knockout mouse models to study Wnt signal transduction. Trends Genet (2006) 1.46
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells. Nat Methods (2014) 1.44
Two populations of endochondral osteoblasts with differential sensitivity to Hedgehog signalling. Development (2009) 1.42
Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. J Clin Oncol (2009) 1.33
Sildenafil and vardenafil, types 5 and 6 phosphodiesterase inhibitors, induce caspase-dependent apoptosis of B-chronic lymphocytic leukemia cells. Blood (2002) 1.33
Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells. J Clin Invest (2011) 1.29
Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia. Cancer (2012) 1.22
Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications. Blood (2006) 1.21
Pancreatic cancer stem cells: emerging target for designing novel therapy. Cancer Lett (2012) 1.16
67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis. J Clin Invest (2013) 1.14
Overexpression of the 67-kD laminin receptor correlates with tumour progression in human colorectal carcinoma. J Pathol (1996) 1.13
The role of nitric oxide in erectile dysfunction: implications for medical therapy. J Clin Hypertens (Greenwich) (2006) 1.11
Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2008) 1.07
Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents. Gastroenterology (2012) 1.04
Multiple functions of the 37/67-kd laminin receptor make it a suitable target for novel cancer gene therapy. Mol Ther (2009) 1.03
In vitro and in vivo anti-allergic effects of 'benifuuki' green tea containing O-methylated catechin and ginger extract enhancement. Cytotechnology (2007) 0.97
Histological and prognostic importance of CD44(+) /CD24(+) /EpCAM(+) expression in clinical pancreatic cancer. Cancer Sci (2013) 0.97
Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. Br J Haematol (2010) 0.95
Construction and validation of a prognostic index for patients with metastatic pancreatic adenocarcinoma. Pancreas (2011) 0.95
How valid are claims for synergy in published clinical studies? Ann Oncol (2012) 0.93
Polyphenon E: a new treatment for external anogenital warts. Br J Dermatol (2009) 0.92
The 67kDa laminin receptor as a primary determinant of anti-allergic effects of O-methylated EGCG. Biochem Biophys Res Commun (2007) 0.89
Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer. J Clin Oncol (2015) 0.87
67-kDa laminin receptor in human bile duct carcinoma. Eur Surg Res (2009) 0.87
Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition. Int J Oncol (2012) 0.85
New insights into pancreatic cancer stem cells. World J Stem Cells (2015) 0.84
Solid-phase synthesis of a combinatorial methylated (±)-epigallocatechin gallate library and the growth-inhibitory effects of these compounds on melanoma B16 cells. Chem Asian J (2010) 0.81
Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes. Cancer Gene Ther (2004) 0.80
Gastric cancer cell adhesion to laminin enhances acquired chemotherapeutic drug resistance mediated by MGr1-Ag/37LRP. Oncol Rep (2014) 0.77
FOXO3 is essential for CD44 expression in pancreatic cancer cells. Oncogene (2016) 0.77
SphK1 inhibitor potentiates the anti-cancer effect of EGCG on leukaemia cells. Br J Haematol (2016) 0.77