Published in Jpn J Pharmacol on November 01, 1988
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The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity (1994) 6.18
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Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell (1995) 4.34
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ACE inhibitors and symptomless dysphagia. Lancet (1998) 2.92
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Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence. Proc Natl Acad Sci U S A (1989) 2.72
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc Natl Acad Sci U S A (1996) 2.70
Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum Genet (2000) 2.50
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Considerable time from the onset of plaque rupture and/or thrombi until the onset of acute myocardial infarction in humans: coronary angiographic findings within 1 week before the onset of infarction. Circulation (2000) 2.42
Production of human alpha-interferon in silkworm using a baculovirus vector. Nature (1985) 2.37
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Adult coronary artery disease probably due to childhood Kawasaki disease. Lancet (1992) 1.97
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Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. Cancer Res (1997) 1.94
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol (1998) 1.93
Age-related decline in the in vitro and in vivo syntheses of anti-tetanus toxoid antibody in humans. J Immunol (1980) 1.78
Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction. Circ Res (1998) 1.78
Adult T cell leukemia. Histological classification and characteristics. Acta Pathol Jpn (1979) 1.74
Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial. Med Pediatr Oncol (2000) 1.72
A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system. J Immunol (1999) 1.69
Augmented expression of atrial natriuretic polypeptide gene in ventricle of human failing heart. J Clin Invest (1989) 1.69
cDNA cloning of a calcineurin B homolog in Saccharomyces cerevisiae. Biochem Biophys Res Commun (1991) 1.68
A new, simple method for cold storage of the pancreas using perfluorochemical. Transplantation (1988) 1.65
A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Ann Neurol (2000) 1.65
Quantitative analysis of myocardial fibrosis in normals, hypertensive hearts, and hypertrophic cardiomyopathy. Br Heart J (1986) 1.61
Supravalvar aortic stenosis: a 29-year review of surgical experience. Ann Thorac Surg (1991) 1.60
Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation (1996) 1.60
Discrimination of brain abscess from necrotic or cystic tumors by diffusion-weighted echo planar imaging. Magn Reson Imaging (1996) 1.59
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. J Immunol (1997) 1.58
The usefulness of computed tomography in the diagnosis of impacted fish bones in the oesophagus. J Laryngol Otol (1998) 1.53
PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients. Leukemia (2008) 1.53
Isolation and characterization of SSE1 and SSE2, new members of the yeast HSP70 multigene family. Gene (1993) 1.52
A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration. Neurology (1999) 1.52
Nor-binaltorphimine: a potent and selective kappa-opioid receptor antagonist with long-lasting activity in vivo. Arch Int Pharmacodyn Ther (1992) 1.51
Highly sensitive ELISA for soluble Fas in serum: increased soluble Fas in the elderly. Clin Chem (1996) 1.49
Molecular mechanism of introduction of the hidden break into the 28S rRNA of insects: implication based on structural studies. Nucleic Acids Res (1986) 1.48
Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasma. Br J Cancer (2012) 1.48
Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins. J Cell Sci (2000) 1.46
Further studies on sperm-immobilizing antibody found in sera of unexplained cases of sterility in women. Am J Obstet Gynecol (1972) 1.45
Investigation of morphological change of lateral and midline fluid percussion injury in rats, using magnetic resonance imaging. Neurosurgery (1997) 1.45
Spontaneous conception and intrauterine pregnancy in a symptomatic missed abortion of ectopic pregnancy conceived in the previous cycle. Hum Reprod (1996) 1.43
Identification of a pentanucleotide telomeric sequence, (TTAGG)n, in the silkworm Bombyx mori and in other insects. Mol Cell Biol (1993) 1.42
Overexpression of 20-oxidase confers a gibberellin-overproduction phenotype in Arabidopsis. Plant Physiol (1998) 1.41
Obvious mRNA and protein expression but absence of mutations of the RET proto-oncogene in parathyroid tumors. Eur J Endocrinol (1996) 1.40
Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet (1998) 1.36
Increased interleukin-1 production and monocyte suppressor cell activity associated with human tuberculosis. Am Rev Respir Dis (1986) 1.35
Adenosine-sensitive atrial reentrant tachycardia originating from the atrioventricular nodal transitional area. J Cardiovasc Electrophysiol (1997) 1.30
Successful induction of immune tolerance to enzyme replacement therapy in canine mucopolysaccharidosis I. Proc Natl Acad Sci U S A (2004) 1.30
Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. I. Requirement of Lyt-1 dull L3T4 bright normal T cells for the induction of thyroiditis. J Immunol (1988) 1.26
Complete agenesis of the dorsal pancreas. J Hepatobiliary Pancreat Surg (1999) 1.26
Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis. Hepatology (1996) 1.25
Chromosome of the enterohemorrhagic Escherichia coli O157:H7; comparative analysis with K-12 MG1655 revealed the acquisition of a large amount of foreign DNAs. DNA Res (1999) 1.24
Construction and evaluation of cDNA libraries for large-scale expressed sequence tag sequencing in wheat (Triticum aestivum L.). Genetics (2004) 1.23
Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy. Circulation (1987) 1.22
Urinary and fecal incontinence in a community-residing older population in Japan. J Am Geriatr Soc (1997) 1.21
Growth and electric current loops in plants. Biophys Chem (1989) 1.20
An increase of soluble Fas, an inhibitor of apoptosis, associated with progression of COPD. Respir Med (1998) 1.20
Postnatal development of a brain-specific subspecies of protein kinase C in rat. J Neurosci (1988) 1.19
Comparison of patient doses in 256-slice CT and 16-slice CT scanners. Br J Radiol (2006) 1.19
Introns and their flanking sequences of Bombyx mori rDNA. Nucleic Acids Res (1984) 1.18
Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFN-gamma production by anti-tumor T cells. Int Immunol (1995) 1.17
Immunocytochemical localization of protein kinase C subspecies in the rat spinal cord: light and electron microscopic study. J Comp Neurol (1990) 1.17
Lack of an association of estrogen receptor alpha gene polymorphisms and transcriptional activity with Alzheimer disease. Arch Neurol (2000) 1.17
Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells. J Ethnopharmacol (1999) 1.16
Histologic studies in percutaneous transluminal coronary angioplasty for chronic total occlusion: comparison of tapering and abrupt types of occlusion and short and long occluded segments. J Am Coll Cardiol (1993) 1.16
The design, expression, and characterization of human insulin-like growth factor II (IGF-II) mutants specific for either the IGF-II/cation-independent mannose 6-phosphate receptor or IGF-I receptor. J Biol Chem (1991) 1.16
Transmural cellular damage and blood flow distribution in early ischemia in pig hearts. Circ Res (1982) 1.15
Effect of caspase inhibitors on myocardial infarct size and myocyte DNA fragmentation in the ischemia-reperfused rat heart. Cardiovasc Res (2000) 1.15
Structural analysis of TRAS1, a novel family of telomeric repeat-associated retrotransposons in the silkworm, Bombyx mori. Mol Cell Biol (1995) 1.15
Structure and chromosomal assignment of the human lectin-like oxidized low-density-lipoprotein receptor-1 (LOX-1) gene. Biochem J (1999) 1.15
Asplenia and polysplenia syndrome. Acta Pathol Jpn (1982) 1.14
Spectrum of immunoregulatory functions and properties of human alveolar macrophages. Am Rev Respir Dis (1987) 1.13
Distinct cellular expression of calcineurin A alpha and A beta in rat brain. J Neurochem (1992) 1.12
Cardiac sympathetic denervation from the early stage of Parkinson's disease: clinical and experimental studies with radiolabeled MIBG. J Nucl Med (2000) 1.12
A critical role for IL-18 in the proliferation and activation of NK1.1+ CD3- cells. J Immunol (1998) 1.12
Neuronal and glial localization of two GABA transporters (GAT1 and GAT3) in the rat cerebellum. Brain Res Mol Brain Res (1996) 1.11
Molecular biology of cervical cancer and its precursors. Cancer (1995) 1.11
A role of interferon-gamma (IFN-gamma) in tumor immunity: T cells with the capacity to reject tumor cells are generated but fail to migrate to tumor sites in IFN-gamma-deficient mice. Cancer Res (2001) 1.11
Tolerance induction of allo-class II H-2 antigen-reactive L3T4+ helper T cells and prolonged survival of the corresponding class II H-2-disparate skin graft. J Immunol (1989) 1.11
Quantitative analysis of contraction band and coagulation necrosis after ischemia and reperfusion in the porcine heart. Circulation (1987) 1.11
Regulation of T cell-dependent and -independent IL-12 production by the three Th2-type cytokines IL-10, IL-6, and IL-4. J Leukoc Biol (1997) 1.11
Requirement for IFN-gamma in IL-12 production induced by collaboration between v(alpha)14(+) NKT cells and antigen-presenting cells. Int Immunol (2000) 1.10
Mechanisms underlying cerebrovascular effects of cigarette smoking in rats in vivo. Stroke (1998) 1.10
Seventy-two-hour preservation of the canine pancreas by the two-layer (Euro-Collins' solution/perfluorochemical) cold storage method. Transplantation (1989) 1.10
A new family of site-specific retrotransposons, SART1, is inserted into telomeric repeats of the silkworm, Bombyx mori. Nucleic Acids Res (1997) 1.10
gamma-Aminobutyric acid in peripheral tissues. Life Sci (1985) 1.10
Transition from compensatory hypertrophy to dilated, failing left ventricles in Dahl salt-sensitive rats. Am J Physiol (1994) 1.10
Thymic stroma-derived T cell growth factor (TSTGF). I. Functional distinction of TSTGF from interleukins 2 and 4 and its preferential growth-promoting effect on helper T cell clones. J Immunol (1987) 1.10
Myocardial fiber diameter and regional distribution in the ventricular wall of normal adult hearts, hypertensive hearts and hearts with hypertrophic cardiomyopathy. Circulation (1983) 1.09
Constitutive expression of interleukin-7 mRNA and production of IL-7 by a cloned murine thymic stromal cell line. J Leukoc Biol (1990) 1.09
Expression of the CRE-BP1 transcriptional regulator binding to the cyclic AMP response element in central nervous system, regenerating liver, and human tumors. Oncogene (1991) 1.08
Presence and function of chondroitin-4-sulfate on recombinant human soluble thrombomodulin. Biochem Biophys Res Commun (1990) 1.08