Published in J Exp Med on May 01, 1994
Cachexia in Gynecological Cancer and the Preventive Role of Weight Training | NCT03200639
Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol (2012) 4.87
Critical contribution of liver natural killer T cells to a murine model of hepatitis. Proc Natl Acad Sci U S A (2000) 3.03
Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol (1995) 2.55
Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. J Clin Invest (2002) 2.40
Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis. J Exp Med (2000) 2.25
Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18. Proc Natl Acad Sci U S A (2000) 2.14
Exercise as a mean to control low-grade systemic inflammation. Mediators Inflamm (2009) 2.09
Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis. J Cell Biol (2000) 1.80
Voluntary exercise protects hippocampal neurons from trimethyltin injury: possible role of interleukin-6 to modulate tumor necrosis factor receptor-mediated neurotoxicity. Brain Behav Immun (2011) 1.64
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. J Clin Invest (2005) 1.63
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure. World J Gastroenterol (2009) 1.54
Functional role of monocytes and macrophages for the inflammatory response in acute liver injury. Front Physiol (2012) 1.49
IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol (2008) 1.48
Importance of Kupffer cells for T-cell-dependent liver injury in mice. Am J Pathol (2000) 1.42
Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome. J Clin Invest (1997) 1.41
Interleukin 6 and liver regeneration. Gut (2000) 1.32
In vivo expression of interleukin-37 reduces local and systemic inflammation in concanavalin A-induced hepatitis. ScientificWorldJournal (2011) 1.27
The kinase inhibitor imatinib mesylate inhibits TNF-{alpha} production in vitro and prevents TNF-dependent acute hepatic inflammation. Proc Natl Acad Sci U S A (2005) 1.23
Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE). J Nutr (2015) 1.20
The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure. Mol Med (1996) 1.16
CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis. Am J Pathol (2007) 1.15
Protective effects of necrostatin-1 against concanavalin A-induced acute hepatic injury in mice. Mediators Inflamm (2013) 1.15
Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects. Pflugers Arch (2003) 1.15
An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity. Proc Natl Acad Sci U S A (2001) 1.14
Impact of physical activity on inflammation: effects on cardiovascular disease risk and other inflammatory conditions. Arch Med Sci (2012) 1.13
Tumor necrosis factor-alpha, interleukin-6, and nitric oxide in sterile ascitic fluid and serum from patients with cirrhosis who subsequently develop ascitic fluid infection. Dig Dis Sci (2001) 1.13
Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice. J Clin Invest (2001) 1.12
Exercise induced adipokine changes and the metabolic syndrome. J Diabetes Res (2014) 1.12
Elevation of interleukin 6 levels in patients with chronic hepatitis due to hepatitis C virus. J Gastroenterol (1997) 1.10
Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol. PLoS One (2011) 1.05
Cancer cachexia prevention via physical exercise: molecular mechanisms. J Cachexia Sarcopenia Muscle (2012) 1.05
Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA. Carcinogenesis (2009) 1.02
NK cells: a double-edged sword in chronic hepatitis B virus infection. Front Immunol (2013) 1.00
Interleukin-6 induces Gr-1+CD11b+ myeloid cells to suppress CD8+ T cell-mediated liver injury in mice. PLoS One (2011) 0.99
Concanavalin A-induced liver injury triggers hepatocyte proliferation. J Clin Invest (1998) 0.98
Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway. Mol Med (2008) 0.96
Treating depression and depression-like behavior with physical activity: an immune perspective. Front Psychiatry (2013) 0.95
Vascular function and inflammation in rheumatoid arthritis: the role of physical activity. Open Cardiovasc Med J (2010) 0.94
Galectin-9 ameliorates Con A-induced hepatitis by inducing CD4(+)CD25(low/int) effector T-Cell apoptosis and increasing regulatory T cell number. PLoS One (2012) 0.93
Role of monocytes and macrophages in experimental and human acute liver failure. World J Gastroenterol (2010) 0.93
Protective effects of astaxanthin on ConA-induced autoimmune hepatitis by the JNK/p-JNK pathway-mediated inhibition of autophagy and apoptosis. PLoS One (2015) 0.92
Fatigue in liver disease: pathophysiology and clinical management. Can J Gastroenterol (2006) 0.92
NKG2A inhibits invariant NKT cell activation in hepatic injury. J Immunol (2009) 0.91
Involvement of natural killer T cells in halothane-induced liver injury in mice. Biochem Pharmacol (2010) 0.90
Overexpression of Interleukin-15 increases susceptibility to lipopolysaccharide-induced liver injury in mice primed with Mycobacterium bovis bacillus Calmette-Guerin. Infect Immun (2004) 0.90
Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits. Arthritis Res Ther (2008) 0.89
15-Deoxy- γ 12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPAR γ and Reduction in NF- κ B Activity. PPAR Res (2014) 0.89
Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. Am J Physiol Endocrinol Metab (2014) 0.88
Questions and controversies: the role of necroptosis in liver disease. Cell Death Discov (2016) 0.88
Altered immune parameters in chronic alcoholic patients at the onset of infection and of septic shock. Crit Care (2004) 0.87
Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system. PLoS One (2009) 0.86
The common inflammatory etiology of depression and cognitive impairment: a therapeutic target. J Neuroinflammation (2014) 0.85
Immunological aspects and therapeutic significance of an autoantibody against histone H1 in a rat model of concanavalin A-induced hepatitis. Immunology (2009) 0.85
Raisins and additional walking have distinct effects on plasma lipids and inflammatory cytokines. Lipids Health Dis (2008) 0.85
RIPK1 protects from TNF-α-mediated liver damage during hepatitis. Cell Death Dis (2016) 0.85
Opposite effects of high and low doses of interleukin-2 on T cell-mediated hepatitis in mice (interleukin-2 on hepatitis). Hepatol Int (2010) 0.84
Protective effects of N-acetylcysteine in concanavalin A-induced hepatitis in mice. Mediators Inflamm (2015) 0.84
Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease. PLoS One (2016) 0.84
Gene expression profiles characterize inflammation stages in the acute lung injury in mice. PLoS One (2010) 0.83
Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice. Am J Pathol (2000) 0.81
Sodium tanshinone IIA sulfonate protects mice from ConA-induced hepatitis via inhibiting NF-kappaB and IFN-gamma/STAT1 pathways. J Clin Immunol (2008) 0.81
Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A (2004) 0.81
(-)-Epigallocatechin-3-gallate protects mice from concanavalin A-induced hepatitis through suppressing immune-mediated liver injury. Clin Exp Immunol (2006) 0.80
The ambiguous boundary between EBV-related hemophagocytic lymphohistiocytosis and systemic EBV-driven T cell lymphoproliferative disorder. Int J Clin Exp Pathol (2014) 0.80
Up-regulation of activating transcription factor-5 suppresses SAP expression to activate T cells in hemophagocytic syndrome associated with Epstein-Barr virus infection and immune disorders. Am J Pathol (2008) 0.80
Local effects of recombinant rat interleukin-6 on the peripheral nervous system. Immunology (1999) 0.79
Clinical associations of host genetic variations in the genes of cytokines in critically ill patients. Clin Exp Immunol (2015) 0.79
Inhibition of immune-mediated concanavalin a-induced liver damage by free-radical scavengers. Dig Dis Sci (2009) 0.78
2,3,7,8-TCDD enhances the sensitivity of mice to concanavalin A immune-mediated liver injury. Toxicol Appl Pharmacol (2012) 0.78
Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury. World J Gastroenterol (2015) 0.78
Protective effects of HFE7A, mouse anti-human/mouse Fas monoclonal antibody against acute and lethal hepatic injury induced by Jo2. Cytotechnology (2009) 0.78
Suppressive role of hepatic dendritic cells in concanavalin A-induced hepatitis. Clin Exp Immunol (2011) 0.77
Tumor-induced CD11b(+) Gr-1(+) myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner. Eur J Immunol (2015) 0.77
Tissue-Specific Regulation of p38α-Mediated Inflammation in Con A-Induced Acute Liver Damage. J Immunol (2015) 0.77
Protective Effects of Dracocephalum heterophyllum in ConA-Induced Acute Hepatitis. Mediators Inflamm (2016) 0.77
The use of synthetic analogues of Arg-Gly-Asp (RGD) and soluble receptor of tumor necrosis factor to prevent acute and chronic experimental liver injury. Yale J Biol Med (1998) 0.77
Up-regulation of granulomatous inflammation in interleukin-6 knockout mice infected with Rhodococcus aurantiacus. Immunology (2003) 0.77
CD49a promotes T-cell-mediated hepatitis by driving T helper 1 cytokine and interleukin-17 production. Immunology (2014) 0.77
Role of ischaemic preconditioning in liver regeneration following major liver resection and transplantation. World J Gastroenterol (2007) 0.77
Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated liver injury by blockade of FADD without loss of nuclear factor-kappaB activation. Ann Surg (2001) 0.76
Autophagy in the liver: cell's cannibalism and beyond. Arch Pharm Res (2016) 0.76
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. Acta Pharmacol Sin (2016) 0.75
Immune mediated liver failure. EXCLI J (2014) 0.75
Trametes versicolor protein YZP activates regulatory B lymphocytes - gene identification through de novo assembly and function analysis in a murine acute colitis model. PLoS One (2013) 0.75
Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response. PLoS One (2015) 0.75
MRI-based assessment of liver perfusion and hepatocyte injury in the murine model of acute hepatitis. MAGMA (2016) 0.75
Suppression of chronic experimental autoimmune neuritis by nasally administered recombinant rat interleukin-6. Immunology (1999) 0.75
A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study. Arthritis Res Ther (2017) 0.75
Hepatic NK cell-mediated hypersensitivity to ConA-induced liver injury in mouse liver expressing hepatitis C virus polyprotein. Oncotarget (2016) 0.75
Immune Evasion Strategies during Chronic Hepatitis B and C Virus Infection. Vaccines (Basel) (2017) 0.75
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature (1988) 13.42
The biology of cachectin/TNF--a primary mediator of the host response. Annu Rev Immunol (1989) 9.63
Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci U S A (1987) 9.26
The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome. J Exp Med (1989) 6.99
Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci U S A (1979) 6.77
Endotoxins and disease mechanisms. Annu Rev Med (1987) 6.07
Transaminase activity in human blood. J Clin Invest (1955) 5.98
Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J Exp Med (1987) 4.63
Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes. J Exp Med (1987) 4.54
A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest (1992) 4.39
T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor. J Exp Med (1992) 4.31
Carbon tetrachloride hepatotoxicity. Pharmacol Rev (1967) 3.77
Retracted Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice. J Immunol (1990) 3.76
Use of monoclonal antibodies to T-cell subsets for immunologic monitoring and treatment in recipients of renal allografts. N Engl J Med (1981) 3.63
Multiple actions of interleukin 6 within a cytokine network. Immunol Today (1988) 3.62
Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun (1986) 3.42
Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. Am J Med (1989) 3.32
IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J Immunol (1989) 3.15
Galactosamine hepatitis: key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death. Rev Physiol Biochem Pharmacol (1974) 2.76
Experimental hepatitis induced by D-galactosamine. Exp Mol Pathol (1968) 2.47
Editorial: Gram-negative-rod bacteremia. N Engl J Med (1974) 2.36
B cell growth and differentiation activity of interleukin-HP1 and related murine plasmacytoma growth factors. Synergy with interleukin 1. Eur J Immunol (1988) 1.99
Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: further evidence for transient in vivo T cell activation. Eur J Immunol (1990) 1.96
Lymphotoxin. Annu Rev Immunol (1988) 1.94
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. Biochem Pharmacol (1989) 1.87
HBsAg retention sensitizes the hepatocyte to injury by physiological concentrations of interferon-gamma. Hepatology (1992) 1.68
Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-alpha. J Immunol (1992) 1.60
Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells. J Immunol (1989) 1.51
Systemic reaction to the anti-T-cell monoclonal antibody OKT3 in relation to serum levels of tumor necrosis factor and interferon-gamma [corrected]. N Engl J Med (1989) 1.34
Regulation of insulin receptor kinase activity by insulin mimickers and an insulin antagonist. Biochem Biophys Res Commun (1983) 1.27
Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone. J Immunol (1991) 1.22
Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice. Hepatology (1990) 1.17
Protection from tumor necrosis factor cytotoxicity by protease inhibitors. Cell Immunol (1987) 1.07
Leukotriene-mediated liver injury. Biochem Pharmacol (1988) 1.03
Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes. Cytokine (1991) 0.90
Interleukin-6 regulates the cytotoxic effect of tumour necrosis factor on U937 cells. Immunology (1992) 0.86
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity (1999) 17.40
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol (1999) 16.86
A gene map of the human genome. Science (1996) 14.32
Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity (1999) 11.64
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell (1992) 10.78
A highly sensitive method to assay FK-506 levels in plasma. Transplant Proc (1987) 8.45
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell (1999) 7.56
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity (1994) 6.18
Convenient test for screening metallo-beta-lactamase-producing gram-negative bacteria by using thiol compounds. J Clin Microbiol (2000) 5.69
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature (1994) 5.33
Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. Nat Genet (1993) 4.96
Organization of the recA gene of Escherichia coli. Proc Natl Acad Sci U S A (1980) 4.90
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell (1995) 4.34
Stimulation by Rad52 of yeast Rad51-mediated recombination. Nature (1998) 4.31
Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80
Nucleotide sequence of the lexA gene of E. coli. Cell (1981) 3.61
Circulating microRNAs in plasma of patients with gastric cancers. Br J Cancer (2010) 3.59
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J Virol (1995) 3.41
Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet (1994) 3.39
Driving, glaucoma, and the law. BMJ (1994) 3.24
Biosynthesis of a 42-kD Polypeptide in the Cytoplasmic Membrane of the Cyanobacterium Anacystis nidulans Strain R2 during Adaptation to Low CO(2) Concentration. Plant Physiol (1986) 3.18
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res (2001) 3.18
Homologous recombination and the roles of double-strand breaks. Trends Biochem Sci (1995) 3.10
Kinetic properties of the blue-light response of stomata. Proc Natl Acad Sci U S A (1985) 3.09
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes (2000) 3.01
Characteristics of purified recA protein and the regulation of its synthesis in vivo. Cold Spring Harb Symp Quant Biol (1979) 2.93
ACE inhibitors and symptomless dysphagia. Lancet (1998) 2.92
Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome. Biochem Biophys Res Commun (1994) 2.89
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. J Immunol (1988) 2.80
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair. Circulation (1999) 2.80
Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing. J Virol (1995) 2.76
Home visits by an occupational therapist for assessment and modification of environmental hazards: a randomized trial of falls prevention. J Am Geriatr Soc (1999) 2.74
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc Natl Acad Sci U S A (1996) 2.70
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells (1998) 2.66
Primary structure of the RAD52 gene in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.56
miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer (2010) 2.51
Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum Genet (2000) 2.50
Replication of bacteriophage DNA. I. Replication of DNA of lambda phage defective in early functions. J Mol Biol (1968) 2.46
"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labeling. Circulation (1998) 2.43
Considerable time from the onset of plaque rupture and/or thrombi until the onset of acute myocardial infarction in humans: coronary angiographic findings within 1 week before the onset of infarction. Circulation (2000) 2.42
Production of human alpha-interferon in silkworm using a baculovirus vector. Nature (1985) 2.37
Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. Circulation (2001) 2.36
Replication of bacteriophage DNA, II. Structure of replicating DNA of phage lambda. Proc Natl Acad Sci U S A (1968) 2.29
Two pigment proteins in spinach chloroplasts. Biochim Biophys Acta (1966) 2.27
RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 2.26
The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. Br J Cancer (2011) 2.25
Regulation of SOS functions: purification of E. coli LexA protein and determination of its specific site cleaved by the RecA protein. Cell (1981) 2.20
Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery. J Physiol (1992) 2.20
A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops. Proc Natl Acad Sci U S A (2000) 2.19
Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination. Genes Cells (1997) 2.18
Discontinuous DNA replication. Annu Rev Biochem (1980) 2.14
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942. Proc Natl Acad Sci U S A (1999) 2.14
Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. Circulation (1999) 2.14
Pathology of the heart in Kawasaki disease. Pediatrics (1978) 2.10
Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure. J Biol Chem (1988) 2.09
Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: primase as the sole priming enzyme. Proc Natl Acad Sci U S A (1985) 2.08
Anterior decompression and stabilization with the Kaneda device for thoracolumbar burst fractures associated with neurological deficits. J Bone Joint Surg Am (1997) 2.06
Direct stimulation of monocyte release of interleukin 1 by mycobacterial protein antigens. J Immunol (1986) 2.05
Effects of gender, age, and fitness level on response of VO2max to training in 60-71 yr olds. J Appl Physiol (1985) (1991) 2.05
Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int Immunol (2000) 2.05
Localization of RecA-like recombination proteins on chromosomes of the lily at various meiotic stages. Genes Dev (1995) 2.04
Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant. Infect Immun (1985) 2.04
Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA. Proc Natl Acad Sci U S A (2001) 2.03
Ingested arsenic and internal cancer: a historical cohort study followed for 33 years. Am J Epidemiol (1995) 1.99
Adult coronary artery disease probably due to childhood Kawasaki disease. Lancet (1992) 1.97
Circulating microRNAs in plasma of patients with oesophageal squamous cell carcinoma. Br J Cancer (2011) 1.97
Laparoscopic removal of a large gastric trichobezoar. J Pediatr Surg (1998) 1.96
Chromogenic substrates for horseshoe crab clotting enzyme. Its application for the assay of bacterial endotoxins. Haemostasis (1978) 1.96
Replication of phage lambda DNA. Cold Spring Harb Symp Quant Biol (1968) 1.95
Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. Cancer Res (1997) 1.94
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol (1998) 1.93
Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens (1998) 1.93
Causes of maternal mortality in Japan. JAMA (2000) 1.92
Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. DNA Res (1997) 1.92
Nocturnal blood pressure fall on ambulatory monitoring in a large international database. The "Ad Hoc' Working Group. Hypertension (1997) 1.90
Genetically engineered mutant of the cyanobacterium Synechococcus PCC 7942 defective in nitrate transport. Proc Natl Acad Sci U S A (1989) 1.88
Two types of functionally distinct NAD(P)H dehydrogenases in Synechocystis sp. strain PCC6803. J Biol Chem (2000) 1.87
Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res (1997) 1.87
Factor structure, reliability, and validity of the Pain Catastrophizing Scale. J Behav Med (1997) 1.87
Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J Immunol (2000) 1.86
Negative control of replication initiation by a novel chromosomal locus exhibiting exceptional affinity for Escherichia coli DnaA protein. Genes Dev (1998) 1.85
Identification and characterization of genes encoding polycyclic aromatic hydrocarbon dioxygenase and polycyclic aromatic hydrocarbon dihydrodiol dehydrogenase in Pseudomonas putida OUS82. J Bacteriol (1994) 1.83
New anterior instrumentation for the management of thoracolumbar and lumbar scoliosis. Application of the Kaneda two-rod system. Spine (Phila Pa 1976) (1996) 1.81
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex. J Neurol Sci (1992) 1.79
Age-related decline in the in vitro and in vivo syntheses of anti-tetanus toxoid antibody in humans. J Immunol (1980) 1.78
Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction. Circ Res (1998) 1.78
Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. EMBO J (1994) 1.77
Effect of ultraviolet irradiation on bacteriophage lambda immunity. J Mol Biol (1967) 1.77
N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. Eur J Biochem (2001) 1.76
Adult T cell leukemia. Histological classification and characteristics. Acta Pathol Jpn (1979) 1.74
Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. Br J Cancer (2011) 1.74
Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress. Circ Res (2000) 1.73