Published in Nucleic Acids Res on May 23, 2017
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics (2010) 53.23
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res (2009) 23.27
A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res (1996) 11.05
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc Natl Acad Sci U S A (2002) 9.60
Quantitative visualization of DNA G-quadruplex structures in human cells. Nat Chem (2013) 4.61
A third essential DNA polymerase in S. cerevisiae. Cell (1990) 4.46
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet (1999) 4.18
In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei. Proc Natl Acad Sci U S A (2001) 3.97
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell (2011) 3.70
Replication fork pausing and recombination or "gimme a break". Genes Dev (2000) 3.65
The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell (1994) 3.52
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat Genet (2002) 3.50
Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells. Nat Methods (2014) 3.20
DNA secondary structures: stability and function of G-quadruplex structures. Nat Rev Genet (2012) 3.15
Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis. Bioinformatics (2009) 3.05
The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell (2000) 2.99
Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae. Mol Cell (2009) 2.65
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nat Chem Biol (2012) 2.41
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo. PLoS Genet (2009) 2.32
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. J Biol Chem (1990) 2.06
Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature (2013) 2.00
Circular dichroism of quadruplex DNAs: applications to structure, cation effects and ligand binding. Methods (2007) 1.99
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem (2008) 1.93
The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes. Genes Dev (2006) 1.87
The G4 genome. PLoS Genet (2013) 1.83
Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol (2008) 1.80
G-quadruplex-induced instability during leading-strand replication. EMBO J (2011) 1.77
Unwinding the functions of the Pif1 family helicases. DNA Repair (Amst) (2010) 1.77
G-quadruplex structures are stable and detectable in human genomic DNA. Nat Commun (2013) 1.72
Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae. Methods Enzymol (2006) 1.63
The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites. Curr Biol (2006) 1.58
Detection of G-quadruplex DNA in mammalian cells. Nucleic Acids Res (2013) 1.53
Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep (2008) 1.51
G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae. PLoS Comput Biol (2010) 1.47
Additional vectors for PCR-based gene tagging in Saccharomyces cerevisiae and Schizosaccharomyces pombe using nourseothricin resistance. Yeast (2005) 1.46
Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: a yeast model. Mutat Res (2003) 1.46
G-quadruplexes and their regulatory roles in biology. Nucleic Acids Res (2015) 1.43
Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) (2008) 1.39
An RNA G-quadruplex is essential for cap-independent translation initiation in human VEGF IRES. J Am Chem Soc (2010) 1.27
Small-molecule-mediated G-quadruplex isolation from human cells. Nat Chem (2010) 1.26
Analysis of the DNA unwinding activity of RecQ family helicases. Methods Enzymol (2006) 1.18
MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics (2001) 1.17
Genomes and G-quadruplexes: for better or for worse. J Mol Biol (2013) 1.10
Determination of gross chromosomal rearrangement rates. Cold Spring Harb Protoc (2010) 0.96
Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites. EMBO J (2015) 0.94
G-quadruplexes and helicases. Nucleic Acids Res (2016) 0.90
Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. Mol Cell (2015) 0.88
Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes. Nucleic Acids Res (2006) 0.88
Polymerase stalling during replication, transcription and translation. Curr Biol (2014) 0.86
Investigation of mRNA quadruplex formation in Escherichia coli. Nat Protoc (2009) 0.85
Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell (2011) 0.84
Replication of Structured DNA and its implication in epigenetic stability. Front Genet (2015) 0.83
Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers. Nat Commun (2015) 0.82
Genetic instability in budding and fission yeast-sources and mechanisms. FEMS Microbiol Rev (2015) 0.80
The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres. PLoS Genet (2015) 0.80
Two-quartet G-quadruplexes formed by DNA sequences containing four contiguous GG runs. J Phys Chem B (2015) 0.78
Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination. DNA Repair (Amst) (2010) 0.78
Characterization of Quadruplex DNA Structure by Circular Dichroism. Curr Protoc Nucleic Acid Chem (2017) 0.75