Pharmacokinetic evidence to support increased doses of rifampin for tuberculosis: results from the HIRIF trial.

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🔗 View Article (PMID 28559269)

Published in Antimicrob Agents Chemother on May 30, 2017

Authors

C A Peloquin1, G E Velásquez2,3, L Lecca3,4, R I Calderón4, J Coit2, M Milstein2, E Osso2, J Jimenez4, K Tintaya4, E Sanchez Garavito5, D Vargas Vasquez6, C D Mitnick3,7, G Davies8

Author Affiliations

1: University of Florida College of Pharmacy and Emerging Pathogens Institute, Gainesville, Florida, USA peloquin@cop.ufl.edu.
2: Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
3: Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
4: Socios En Salud, Lima, Peru.
5: Hospital Nacional Sergio Bernales, Lima, Peru.
6: Hospital Nacional Hipólito Unanue, Lima, Peru.
7: Partners In Health, Boston, Massachusetts, USA.
8: Institutes of Infection and Global Health and Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

Associated clinical trials:

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF) | NCT03982277

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