Published in Lancet on February 23, 1985
Feasibility, safety, and efficacy of domiciliary thrombolysis by general practitioners: Grampian region early anistreplase trial. GREAT Group. BMJ (1992) 4.34
Excessive morphine requirements after pre-hospital nalbuphine analgesia. J Accid Emerg Med (1999) 2.34
The management of suspected myocardial infarction by Scottish general practitioners with access to community hospital beds. Br J Gen Pract (1990) 1.79
Potential impact of emergency intervention on sudden deaths from coronary heart disease in Glasgow. Br Heart J (1992) 1.38
General practitioners and emergency treatment for patients with suspected myocardial infarction: last chance for excellence? Br J Gen Pract (1992) 1.17
The need for better pre-hospital analgesia. Arch Emerg Med (1993) 1.06
Integration of ambulance staff trained in cardiopulmonary resuscitation with a medical team providing prehospital coronary care. Br Heart J (1989) 0.99
Referrals for coronary angiography in a high risk population. Qual Health Care (1993) 0.98
A history of prehospital coronary care. Ulster Med J (1996) 0.96
What proportion of patients with myocardial infarction are suitable for thrombolysis? Br Heart J (1987) 0.92
Twenty years of prehospital coronary care. Br Heart J (1986) 0.83
Immediate coronary care in general practice--a three-year review. Ulster Med J (1985) 0.75
Mobile coronary care and mortality from ischaemic heart disease in a predominantly rural community. Ulster Med J (1988) 0.75
Thrombolytic therapy for myocardial infarction facilitated by mobile coronary care. Ulster Med J (2004) 0.75
Threads of life and health--a heritage of quality in practice. Ulster Med J (2011) 0.75
Effect of general practitioners' advice against smoking. Br Med J (1979) 24.07
THE NATURE OF THE PERIPHERAL RESISTANCE IN ARTERIAL HYPERTENSION WITH SPECIAL REFERENCE TO THE VASOMOTOR SYSTEM. J Clin Invest (1936) 18.94
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol (2000) 16.83
Intercapillary Lesions in the Glomeruli of the Kidney. Am J Pathol (1936) 12.50
Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med (1999) 11.27
Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol (1993) 10.87
A plethysmographic method for measuring systolic blood pressure in the intact rat. J Physiol (1938) 7.20
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet (2001) 6.92
Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J Virol (1991) 6.19
P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev (1989) 5.76
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60
Benign and Malignant Hypertension and Nephrosclerosis: A Clinical and Pathological Study. Am J Pathol (1936) 4.43
International criteria for diagnosis, staging, and response to treatment in patients with neuroblastoma. J Clin Oncol (1988) 4.35
Genetic evidence for the spread of agriculture in Europe by demic diffusion. Nature (1991) 4.34
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J Virol (2004) 4.12
A cytogenetic study of 1000 spontaneous abortions. Ann Hum Genet (1980) 3.82
A proposed staging for children with neuroblastoma. Children's cancer study group A. Cancer (1971) 3.71
Atypical beta-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature (1984) 3.64
Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A (1997) 3.61
Inflammatory Lesions in the Glomeruli in Pyelonephritis in Relation to Hypertension and Renal Insufficiency. Am J Pathol (1936) 3.52
The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia. QJM (1996) 3.31
New world views: preparing physicians in training for global health work. Fam Med (2000) 3.23
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev (1996) 3.21
Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene. Cell (1988) 2.91
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes Dev (1999) 2.87
The increasing incidence of central nervous system leukemia in children. (Children's Cancer Study Group A). Cancer (1970) 2.82
Plasma nicotine levels after smoking cigarettes with high, medium, and low nicotine yields. Br Med J (1975) 2.80
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface. J Mol Biol (1996) 2.80
The treatment of Wilms' tumor: Results of the national Wilms' tumor study. Cancer (1976) 2.80
Comparison of effect on tobacco consumption and carbon monoxide absorption of changing to high and low nicotine cigarettes. Br Med J (1973) 2.65
Special pattern of widespread neuroblastoma with a favourable prognosis. Lancet (1971) 2.65
RNA secondary structure prediction based on free energy and phylogenetic analysis. J Mol Biol (1999) 2.65
Effect of nicotine chewing gum on smoking behaviour and as an aid to cigarette withdrawal. Br Med J (1976) 2.41
Fusion protein of the paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activation. Virology (2000) 2.39
A computer-derived protocol to aid in the diagnosis of emergency room patients with acute chest pain. N Engl J Med (1982) 2.28
Stimulation and suppression of PCR-mediated recombination. Nucleic Acids Res (1998) 2.17
Survival in childhood acute lymphocytic leukemia: effect of protocol and place of treatment. Cancer Invest (1983) 2.16
Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther (1995) 2.11
A microtest for the quantitation of rabies virus neutralizing antibodies. J Biol Stand (1979) 2.10
The treatment and prevention of obesity: a systematic review of the literature. Int J Obes Relat Metab Disord (1997) 2.10
Improving the detection rate of early gastric cancer requires more than open access gastroscopy: a five year study. Gut (1997) 2.09
On the scale of global demographic convergence, 1950-2000. Popul Dev Rev (2001) 2.07
Randomized comparison of enoxaparin with unfractionated heparin following fibrinolytic therapy for acute myocardial infarction. Eur Heart J (2002) 2.06
Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. J Biol Chem (1994) 2.04
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene (2007) 2.00
Antibodies to proteus in rheumatoid arthritis. Lancet (1985) 1.96
Therapeutic Trial of Methionine in Infective Hepatitis. Br Med J (1945) 1.95
The effectiveness of chemotherapy for treatment of high grade astrocytoma in children: results of a randomized trial. A report from the Childrens Cancer Study Group. J Neurooncol (1989) 1.92
Acute chest pain in the emergency room. Identification and examination of low-risk patients. Arch Intern Med (1985) 1.86
The rat lipolytic beta-adrenoceptor: studies using novel beta-adrenoceptor agonists. Eur J Pharmacol (1984) 1.85
Incidence of childhood cancer: experience of a decade in a population-based registry. J Natl Cancer Inst (1983) 1.85
UV-Stimulated K Efflux from Rose Cells: Counterion and Inhibitor Studies. Plant Physiol (1982) 1.85
Comparison of increases in carboxyhaemoglobin after smoking "extra-mild" and "non-mild" cigarettes. Lancet (1973) 1.84
Perturbation of Chara Plasmalemma Transport Function by 2[4(2',4'-Dichlorophenoxy)phenoxy]propionic Acid. Plant Physiol (1984) 1.83
Variability of the lytic susceptibility of Neisseria gonorrhoeae to human sera. J Immunol (1977) 1.81
Idiopathic granulomatous mastitis. A report of three cases and review of the literature. Arch Pathol Lab Med (1994) 1.79
Blood cholesterol: is population screening warranted in the UK? Lancet (1989) 1.76
Characterization of the humoral immune response to Klebsiella species in inflammatory bowel disease and ankylosing spondylitis. Br J Rheumatol (1998) 1.69
GSK3: a SHAGGY frog story. Trends Cell Biol (1996) 1.65
The Mediterranean diet revisited--towards resolving the (French) paradox. QJM (2000) 1.61
Evaluation of chromogenic meticillin-resistant Staphylococcus aureus media: sensitivity versus turnaround time. J Hosp Infect (2012) 1.58
Increased antibiotic resistance of Neisseria gonorrhoeae in Korea. Antimicrob Agents Chemother (1976) 1.58
Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population. Hum Mol Genet (1997) 1.55
Appendicitis in pregnancy: an ongoing diagnostic dilemma. Colorectal Dis (2008) 1.54
Association of dehydroepiandrosterone sulfate, body composition, and physical fitness in independent community-dwelling older men and women. J Am Geriatr Soc (1998) 1.53
Co-induction and laryngeal mask insertion. A comparison of thiopentone versus propofol. Anaesthesia (1997) 1.52
Inhibition by glibenclamide of the vasorelaxant action of cromakalim in the rat. Br J Pharmacol (1989) 1.52
A randomized clinical trial of granulocyte transfusions for infection in acute leukemia. N Engl J Med (1977) 1.51
2.8 A crystal structure of the malachite green aptamer. J Mol Biol (2000) 1.49
Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis. Lancet (1990) 1.49
The structural basis for molecular recognition by the vitamin B 12 RNA aptamer. Nat Struct Biol (2000) 1.48
Evaluation of an inflammation-based prognostic score (GPS) in patients with metastatic breast cancer. Br J Cancer (2006) 1.48
Prognostic factor in neuroblastoma. Cancer (1987) 1.47
Pre-hospital coronary care and coronary fatality in the Belfast and Glasgow MONICA populations. Int J Epidemiol (2005) 1.47
Cloning, expression, and alternative splicing of the receptor for anti-Müllerian hormone. Mol Endocrinol (1994) 1.46
Targeting motifs and functional parameters governing the assembly of connexins into gap junctions. Biochem J (2000) 1.45
A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM Study. Arterioscler Thromb (1992) 1.45
Defibrillators in general practice. Br Med J (Clin Res Ed) (1984) 1.45
Extended forensic evaluation when sexual abuse is suspected: a multisite field study. Child Maltreat (2001) 1.43
Is rheumatoid arthritis a form of reactive arthritis? J Rheumatol (2000) 1.42
Trichomycosis axillaris: a different view. J Am Acad Dermatol (1989) 1.42
An advance notification letter increases participation in colorectal cancer screening. J Med Screen (2007) 1.42
Prospective comparison of clinical and echocardiographic diagnosis of rheumatic carditis: long term follow up of patients with subclinical disease. Heart (2001) 1.42
Sub-regional revenue allocations and SMRs: progress towards equity? Hosp Health Serv Rev (1987) 1.39
Distribution of lipid variables in subjects in Belfast, Northern Ireland and Taiyuan, P R China. Atherosclerosis (1993) 1.39
Conditioned and unconditioned stimuli increase frontal cortical and hippocampal acetylcholine release: effects of novelty, habituation, and fear. J Neurosci (1996) 1.38
Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation. Oncogene (2010) 1.37
1995 Standards for Acute Care Organizations not responsive to customer voices. Leadersh Health Serv (1995) 1.37
Accumulation of extracellular matrix and developmental dysregulation in the pancreas by transgenic production of transforming growth factor-beta 1. Am J Pathol (1995) 1.37
Mutations of the mitochondrial ND1 gene as a cause of MELAS. J Med Genet (2004) 1.35
The epidemiology of disease expenses. The costs of caring for children with cancer. JAMA (1985) 1.35
Acute superior mesenteric ischaemia. Br J Surg (1987) 1.35
P-element-mediated enhancer detection applied to the study of oogenesis in Drosophila. Development (1989) 1.34
Laser-mediated, site-specific inactivation of RNA transcripts. Proc Natl Acad Sci U S A (1999) 1.34
Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma. Proc Natl Acad Sci U S A (2000) 1.33
Direct determination of the membrane affinities of individual amino acids. Biochemistry (1996) 1.32
Helicobacter pylori infection: relation with cardiovascular risk factors, ischaemic heart disease, and social class. Br Heart J (1995) 1.31
An interstitial deletion of chromosome 9 in a girl with multiple congenital anomalies. J Med Genet (1977) 1.30
Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations. Genet Epidemiol (1999) 1.30
St-segment displacement and early hospital discharge in acute myocardial infarction. Lancet (1973) 1.28