Published in J Mol Biol on July 19, 1996
3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures. Nat Protoc (2008) 4.61
Origins of specificity in protein-DNA recognition. Annu Rev Biochem (2010) 4.43
New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB. Genes Dev (1998) 3.45
Catabolite activator protein: DNA binding and transcription activation. Curr Opin Struct Biol (2004) 2.91
Transcription activation at class II CAP-dependent promoters: two interactions between CAP and RNA polymerase. Cell (1996) 2.88
NUCPLOT: a program to generate schematic diagrams of protein-nucleic acid interactions. Nucleic Acids Res (1997) 2.81
Dynamic activation of an allosteric regulatory protein. Nature (2009) 2.61
Structural basis for cAMP-mediated allosteric control of the catabolite activator protein. Proc Natl Acad Sci U S A (2009) 2.39
A comparative genomics approach to prediction of new members of regulons. Genome Res (2001) 2.37
The evolution of DNA regulatory regions for proteo-gamma bacteria by interspecies comparisons. Genome Res (2002) 2.22
Quantitative parameters for amino acid-base interaction: implications for prediction of protein-DNA binding sites. Nucleic Acids Res (1998) 1.94
A simple mechanism for co-dependence on two activators at an Escherichia coli promoter. EMBO J (2001) 1.43
CO-sensing mechanisms. Microbiol Mol Biol Rev (2004) 1.30
Non-canonical CRP sites control competence regulons in Escherichia coli and many other gamma-proteobacteria. Nucleic Acids Res (2006) 1.28
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex. Proc Natl Acad Sci U S A (2009) 1.26
Staphylococcus aureus ArcR controls expression of the arginine deiminase operon. J Bacteriol (2007) 1.21
The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds. EMBO J (1999) 1.17
Transcription activation mediated by a cyclic AMP receptor protein from Thermus thermophilus HB8. J Bacteriol (2007) 1.17
Structural basis for the regulation of NtcA-dependent transcription by proteins PipX and PII. Proc Natl Acad Sci U S A (2010) 1.15
Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc Natl Acad Sci U S A (2010) 1.14
Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand. Proc Natl Acad Sci U S A (2011) 1.13
An analysis of the relationship between hydration and protein-DNA interactions. Biophys J (1998) 1.09
Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. J Mol Biol (2006) 1.07
Reconstruction of the core and extended regulons of global transcription factors. PLoS Genet (2010) 1.06
Use of structural DNA properties for the prediction of transcription-factor binding sites in Escherichia coli. Nucleic Acids Res (2010) 1.03
Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspective. Microbiol Mol Biol Rev (2013) 1.02
The Product of arcR, the sixth gene of the arc operon of Lactobacillus sakei, is essential for expression of the arginine deiminase pathway. Appl Environ Microbiol (2002) 1.02
The Pseudomonas aeruginosa Vfr regulator controls global virulence factor expression through cyclic AMP-dependent and -independent mechanisms. J Bacteriol (2010) 1.01
Structure of the heterodimeric ecdysone receptor DNA-binding complex. EMBO J (2003) 1.01
The structure of full-length LysR-type transcriptional regulators. Modeling of the full-length OxyR transcription factor dimer. Nucleic Acids Res (2003) 1.01
DNA binding sites for the Mlc and NagC proteins: regulation of nagE, encoding the N-acetylglucosamine-specific transporter in Escherichia coli. Nucleic Acids Res (2001) 0.98
Requirement for two copies of RNA polymerase alpha subunit C-terminal domain for synergistic transcription activation at complex bacterial promoters. Genes Dev (2002) 0.96
Structural insights into the mechanism of the allosteric transitions of Mycobacterium tuberculosis cAMP receptor protein. J Biol Chem (2009) 0.95
Charge neutralization and DNA bending by the Escherichia coli catabolite activator protein. Nucleic Acids Res (2002) 0.94
Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations. Biochemistry (2012) 0.93
Modeling helix-turn-helix protein-induced DNA bending with knowledge-based distance restraints. Biophys J (1999) 0.92
Heme displacement mechanism of CooA activation: mutational and Raman spectroscopic evidence. J Biol Chem (2006) 0.91
Cyclic AMP receptor protein and RhaR synergistically activate transcription from the L-rhamnose-responsive rhaSR promoter in Escherichia coli. J Bacteriol (2005) 0.91
A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability. J Bacteriol (1997) 0.90
Binding sites of different geometries for the 16-3 phage repressor. Proc Natl Acad Sci U S A (2002) 0.89
Mechanism of the CO-sensing heme protein CooA: new insights from the truncated heme domain and UVRR spectroscopy. J Inorg Biochem (2007) 0.88
The cAMP receptor protein CRP can function as an osmoregulator of transcription in Escherichia coli. Genes Dev (1999) 0.87
Induced fit and the entropy of structural adaptation in the complexation of CAP and lambda-repressor with cognate DNA sequences. Biophys J (2005) 0.87
Switching control of expression of ptsG from the Mlc regulon to the NagC regulon. J Bacteriol (2008) 0.87
Point mutations within the streptococcal regulator of virulence (Srv) alter protein-DNA interactions and Srv function. Microbiology (2008) 0.87
Axis curvature and ligand induced bending in the CAP-DNA oligomers. Biophys J (2004) 0.87
The molecular basis for control of ETEC enterotoxin expression in response to environment and host. PLoS Pathog (2015) 0.85
Simulation of (125)I decay in a synthetic oligodeoxynucleotide with normal and distorted geometry and the role of radiation and non-radiation actions. Radiat Environ Biophys (2004) 0.84
Protein-DNA photo-crosslinking with a genetically encoded benzophenone-containing amino acid. Bioorg Med Chem Lett (2009) 0.83
Involvement of the global Crp regulator in cyclic AMP-dependent utilization of aromatic amino acids by Pseudomonas putida. J Bacteriol (2011) 0.83
The N-terminal capping propensities of the D-helix modulate the allosteric activation of the Escherichia coli cAMP receptor protein. J Biol Chem (2012) 0.83
DNA bending induced by carbocyclic sugar analogs constrained to the north conformation. Biopolymers (2007) 0.82
The crystal structures of apo and cAMP-bound GlxR from Corynebacterium glutamicum reveal structural and dynamic changes upon cAMP binding in CRP/FNR family transcription factors. PLoS One (2014) 0.82
Backbone NMR assignments of a high molecular weight protein (47 kDa), cyclic AMP receptor protein (apo-CRP) J Biomol NMR (2000) 0.82
KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA. Nucleic Acids Res (2015) 0.81
Vibrational coherence spectroscopy of the heme domain in the CO-sensing transcriptional activator CooA. J Am Chem Soc (2011) 0.81
The crystal structure of non-modified and bipyridine-modified PNA duplexes. Chemistry (2010) 0.81
Specific contacts between residues in the DNA-binding domain of the TyrR protein and bases in the operator of the tyrP gene of Escherichia coli. J Bacteriol (1999) 0.80
Mapping cyclic nucleotide-induced conformational changes in cyclicAMP receptor protein by a protein footprinting technique using different chemical proteases. Protein Sci (1999) 0.80
Cation binding linked to a sequence-specific CAP-DNA interaction. Biophys Chem (2006) 0.80
Dynamic Allostery of the Catabolite Activator Protein Revealed by Interatomic Forces. PLoS Comput Biol (2015) 0.80
The structure of Bradyrhizobium japonicum transcription factor FixK2 unveils sites of DNA binding and oxidation. J Biol Chem (2013) 0.80
Cyclic AMP receptor protein regulates cspE, an early cold-inducible gene, in Escherichia coli. J Bacteriol (2011) 0.80
Structure of catabolite activator protein with cobalt(II) and sulfate. Acta Crystallogr F Struct Biol Commun (2014) 0.79
Dissecting direct and indirect readout of cAMP receptor protein DNA binding using an inosine and 2,6-diaminopurine in vitro selection system. Nucleic Acids Res (2008) 0.79
Enhanced expression of membrane proteins in E. coli with a P(BAD) promoter mutant: synergies with chaperone pathway engineering strategies. Microb Cell Fact (2011) 0.78
Crystallization and preliminary X-ray analysis of the CRP-cAMP-DNA (full length) complex. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
DNA bending by bHLH charge variants. Nucleic Acids Res (2006) 0.77
Structures during binding of cAMP receptor to promoter DNA: promoter search slowed by non-specific sites. Eur Biophys J (2012) 0.77
Contributions of the histidine side chain and the N-terminal alpha-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH. Biochemistry (2010) 0.76
Binding by TRBP-dsRBD2 Does Not Induce Bending of Double-Stranded RNA. Biophys J (2016) 0.75
Interaction of calicheamicin gamma1(I) and its related carbohydrates with DNA-protein complexes. Proc Natl Acad Sci U S A (1999) 0.75
Crystallization and preliminary X-ray diffraction analysis of D53H mutant Escherichia coli cAMP receptor protein. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans. PLoS One (2016) 0.75
Gly184 of the Escherichia coli cAMP receptor protein provides optimal context for both DNA binding and RNA polymerase interaction. J Microbiol (2017) 0.75
The Transcriptional Regulators of the CRP Family Regulate Different Essential Bacterial Functions and Can Be Inherited Vertically and Horizontally. Front Microbiol (2017) 0.75
Effect of general practitioners' advice against smoking. Br Med J (1979) 24.07
THE NATURE OF THE PERIPHERAL RESISTANCE IN ARTERIAL HYPERTENSION WITH SPECIAL REFERENCE TO THE VASOMOTOR SYSTEM. J Clin Invest (1936) 18.94
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol (2000) 16.83
Intercapillary Lesions in the Glomeruli of the Kidney. Am J Pathol (1936) 12.50
Macromolecular Crystallographic Information File. Methods Enzymol (1997) 11.94
Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med (1999) 11.27
A plethysmographic method for measuring systolic blood pressure in the intact rat. J Physiol (1938) 7.20
New parameters for the refinement of nucleic acid-containing structures. Acta Crystallogr D Biol Crystallogr (1996) 6.92
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet (2001) 6.92
Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J Virol (1991) 6.19
Transcription activation by catabolite activator protein (CAP). J Mol Biol (1999) 6.08
P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev (1989) 5.76
Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution. Science (1994) 5.00
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72
Benign and Malignant Hypertension and Nephrosclerosis: A Clinical and Pathological Study. Am J Pathol (1936) 4.43
Genetic evidence for the spread of agriculture in Europe by demic diffusion. Nature (1991) 4.34
A standard reference frame for the description of nucleic acid base-pair geometry. J Mol Biol (2001) 4.29
Promoter structure, promoter recognition, and transcription activation in prokaryotes. Cell (1994) 4.10
Aromatic hydrogen bond in sequence-specific protein DNA recognition. Nat Struct Biol (1996) 3.91
An overview of the structures of protein-DNA complexes. Genome Biol (2000) 3.90
A cytogenetic study of 1000 spontaneous abortions. Ann Hum Genet (1980) 3.82
The PDB data uniformity project. Nucleic Acids Res (2001) 3.65
Atypical beta-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature (1984) 3.64
Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A (1997) 3.61
Inflammatory Lesions in the Glomeruli in Pyelonephritis in Relation to Hypertension and Renal Insufficiency. Am J Pathol (1936) 3.52
New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB. Genes Dev (1998) 3.45
Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli. Nature (1984) 3.42
Protein-DNA interactions: A structural analysis. J Mol Biol (1999) 3.38
New world views: preparing physicians in training for global health work. Fam Med (2000) 3.23
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev (1996) 3.21
Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase. Nucleic Acids Res (1991) 3.18
Protein-RNA interactions: a structural analysis. Nucleic Acids Res (2001) 2.92
Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene. Cell (1988) 2.91
Domain organization of RNA polymerase alpha subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding. Cell (1994) 2.89
Transcription activation at class II CAP-dependent promoters: two interactions between CAP and RNA polymerase. Cell (1996) 2.88
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes Dev (1999) 2.87
Plasma nicotine levels after smoking cigarettes with high, medium, and low nicotine yields. Br Med J (1975) 2.80
DNA-binding determinants of the alpha subunit of RNA polymerase: novel DNA-binding domain architecture. Genes Dev (1996) 2.72
Comparison of effect on tobacco consumption and carbon monoxide absorption of changing to high and low nicotine cigarettes. Br Med J (1973) 2.65
RNA secondary structure prediction based on free energy and phylogenetic analysis. J Mol Biol (1999) 2.65
Mechanism of ATP-dependent promoter melting by transcription factor IIH. Science (2000) 2.62
Effect of nicotine chewing gum on smoking behaviour and as an aid to cigarette withdrawal. Br Med J (1976) 2.41
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein. Nat Struct Biol (1997) 2.41
Hydration structure of a collagen peptide. Structure (1995) 2.28
A computer-derived protocol to aid in the diagnosis of emergency room patients with acute chest pain. N Engl J Med (1982) 2.28
Mobile coronary care and community mortality from myocardial infarction. Lancet (1985) 2.27
Structural organization of the RNA polymerase-promoter open complex. Cell (2000) 2.25
Consensus DNA site for the Escherichia coli catabolite gene activator protein (CAP): CAP exhibits a 450-fold higher affinity for the consensus DNA site than for the E. coli lac DNA site. Nucleic Acids Res (1989) 2.24
Transcription activation at class II CAP-dependent promoters. Mol Microbiol (1997) 2.22
Translocation of sigma(70) with RNA polymerase during transcription: fluorescence resonance energy transfer assay for movement relative to DNA. Cell (2001) 2.17
Stimulation and suppression of PCR-mediated recombination. Nucleic Acids Res (1998) 2.17
Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit. Genes Dev (1999) 2.13
Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther (1995) 2.11
A microtest for the quantitation of rabies virus neutralizing antibodies. J Biol Stand (1979) 2.10
The treatment and prevention of obesity: a systematic review of the literature. Int J Obes Relat Metab Disord (1997) 2.10
Improving the detection rate of early gastric cancer requires more than open access gastroscopy: a five year study. Gut (1997) 2.09
Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation. Proc Natl Acad Sci U S A (1993) 2.08
Site-specific incorporation of fluorescent probes into protein: hexahistidine-tag-mediated fluorescent labeling with (Ni(2+):nitrilotriacetic Acid (n)-fluorochrome conjugates. J Am Chem Soc (2001) 2.08
On the scale of global demographic convergence, 1950-2000. Popul Dev Rev (2001) 2.07
Randomized comparison of enoxaparin with unfractionated heparin following fibrinolytic therapy for acute myocardial infarction. Eur Heart J (2002) 2.06
Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. J Biol Chem (1994) 2.04
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene (2007) 2.00
Antibodies to proteus in rheumatoid arthritis. Lancet (1985) 1.96
Therapeutic Trial of Methionine in Infective Hepatitis. Br Med J (1945) 1.95
Molecular basis of DNA sequence recognition by the catabolite gene activator protein: detailed inferences from three mutations that alter DNA sequence specificity. Proc Natl Acad Sci U S A (1984) 1.94
Trajectory of DNA in the RNA polymerase II transcription preinitiation complex. Proc Natl Acad Sci U S A (1997) 1.89
Netropsin, a DNA-binding oligopeptide structural and binding studies. Biochim Biophys Acta (1979) 1.89
Location, structure, and function of the target of a transcriptional activator protein. Genes Dev (1994) 1.88
DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein. J Biol Chem (1992) 1.88
Crystal structure of a naturally occurring dinucleoside phoaphate: uridylyl 3',5'-adenosine phosphate model for RNA chain folding. J Mol Biol (1972) 1.87
Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). II. Role at Class I and class II CAP-dependent promoters. J Mol Biol (1994) 1.86
Acute chest pain in the emergency room. Identification and examination of low-risk patients. Arch Intern Med (1985) 1.86
Rapid RNA polymerase genetics: one-day, no-column preparation of reconstituted recombinant Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A (1995) 1.85
The rat lipolytic beta-adrenoceptor: studies using novel beta-adrenoceptor agonists. Eur J Pharmacol (1984) 1.85
UV-Stimulated K Efflux from Rose Cells: Counterion and Inhibitor Studies. Plant Physiol (1982) 1.85
Comparison of increases in carboxyhaemoglobin after smoking "extra-mild" and "non-mild" cigarettes. Lancet (1973) 1.84
Perturbation of Chara Plasmalemma Transport Function by 2[4(2',4'-Dichlorophenoxy)phenoxy]propionic Acid. Plant Physiol (1984) 1.83
Variability of the lytic susceptibility of Neisseria gonorrhoeae to human sera. J Immunol (1977) 1.81
Idiopathic granulomatous mastitis. A report of three cases and review of the literature. Arch Pathol Lab Med (1994) 1.79
High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex. Proc Natl Acad Sci U S A (1996) 1.78
Identification of the target of a transcription activator protein by protein-protein photocrosslinking. Science (1994) 1.77
Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. Proc Natl Acad Sci U S A (2001) 1.76
Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP. Proc Natl Acad Sci U S A (1987) 1.75
Transcription activation at Class II CRP-dependent promoters: identification of determinants in the C-terminal domain of the RNA polymerase alpha subunit. EMBO J (1998) 1.73
Fluorescence anisotropy: rapid, quantitative assay for protein-DNA and protein-protein interaction. Methods Enzymol (1996) 1.72
Sequence dependent conformational variations of collagen triple-helical structure. Nat Struct Biol (1999) 1.71
Structure of a dinucleoside phosphate--drug complex as model for nucleic acid--drug interaction. Nature (1977) 1.71
The functional subunit of a dimeric transcription activator protein depends on promoter architecture. EMBO J (1994) 1.70
Characterization of the humoral immune response to Klebsiella species in inflammatory bowel disease and ankylosing spondylitis. Br J Rheumatol (1998) 1.69
GSK3: a SHAGGY frog story. Trends Cell Biol (1996) 1.65
RNA polymerase beta' subunit: a target of DNA binding-independent activation. Science (1997) 1.63
Evidence for a contact between glutamine-18 of lac repressor and base pair 7 of lac operator. Proc Natl Acad Sci U S A (1986) 1.59
Increased antibiotic resistance of Neisseria gonorrhoeae in Korea. Antimicrob Agents Chemother (1976) 1.58