Photobiomodulation and the brain: a new paradigm.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28580093)

Published in J Opt on December 14, 2016

Authors

Madison Hennessy1, Michael R Hamblin2,3,4

Author Affiliations

1: Briarcliff High School, Briarcliff Manor, NY, USA.
2: Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
3: Department of Dermatology, Harvard Medical School, Boston, MA, USA.
4: Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.

Articles cited by this

(truncated to the top 100)

Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials. Lancet (2009) 4.53

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci U S A (2001) 3.01

Biphasic dose response in low level light therapy. Dose Response (2009) 2.78

Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase. J Biol Chem (2004) 2.36

A quantitative comparison of NIRS and fMRI across multiple cognitive tasks. Neuroimage (2010) 2.29

Mitochondrial signaling in mammalian cells activated by red and near-IR radiation. Photochem Photobiol (2008) 2.22

White matter damage and cognitive impairment after traumatic brain injury. Brain (2010) 2.11

Therapeutic photobiomodulation for methanol-induced retinal toxicity. Proc Natl Acad Sci U S A (2003) 1.88

Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems. Hum Psychopharmacol (2007) 1.77

Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts. PLoS One (2011) 1.76

Low-level laser therapy applied transcranially to rats after induction of stroke significantly reduces long-term neurological deficits. Stroke (2006) 1.72

Biphasic dose response in low level light therapy - an update. Dose Response (2011) 1.69

Clinical trials in traumatic brain injury: past experience and current developments. Neurotherapeutics (2010) 1.69

Transcranial laser therapy in acute stroke treatment: results of neurothera effectiveness and safety trial 3, a phase III clinical end point device trial. Stroke (2014) 1.67

[The effect of laser beams on the growth of hair in mice]. Radiobiol Radiother (Berl) (1968) 1.66

TRPV4 channels mediate the infrared laser-evoked response in sensory neurons. J Neurophysiol (2012) 1.45

Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR-A radiation. IUBMB Life (2010) 1.43

Alzheimer's disease. Lancet (2016) 1.41

Mitochondrial ROS--radical detoxification, mediated by protein kinase D. Trends Cell Biol (2006) 1.36

Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety. Behav Brain Funct (2009) 1.35

Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg (2013) 1.34

The role of inflammation in depression: from evolutionary imperative to modern treatment target. Nat Rev Immunol (2015) 1.28

Transcranial infrared laser therapy improves clinical rating scores after embolic strokes in rabbits. Stroke (2004) 1.27

Effect of pulsing in low-level light therapy. Lasers Surg Med (2010) 1.21

Simulation of near-infrared light absorption considering individual head and prefrontal cortex anatomy: implications for optical neuroimaging. PLoS One (2011) 1.21

Mast-cell degranulation induced by physical stimuli involves the activation of transient-receptor-potential channel TRPV2. Physiol Res (2011) 1.21

Transcranial near-infrared light therapy improves motor function following embolic strokes in rabbits: an extended therapeutic window study using continuous and pulse frequency delivery modes. Neuroscience (2007) 1.18

Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice. PLoS One (2011) 1.15

Transcranial laser therapy attenuates amyloid-β peptide neuropathology in amyloid-β protein precursor transgenic mice. J Alzheimers Dis (2011) 1.12

Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias. Brain (2011) 1.11

Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans. Neuroscience (2012) 1.11

Dentate gyrus neurogenesis and depression. Prog Brain Res (2007) 1.10

The role of NOS in heart failure: lessons from murine genetic models. Heart Fail Rev (2002) 1.08

Low-level laser (light) therapy (LLLT) for treatment of hair loss. Lasers Surg Med (2013) 1.08

Dose response effects of 810 nm laser light on mouse primary cortical neurons. Lasers Surg Med (2011) 1.06

Significant improvements in cognitive performance post-transcranial, red/near-infrared light-emitting diode treatments in chronic, mild traumatic brain injury: open-protocol study. J Neurotrauma (2014) 1.05

The role of metals in the etiology of Alzheimer's disease. J Alzheimers Dis (2007) 1.04

Therapeutic photobiomodulation: nitric oxide and a novel function of mitochondrial cytochrome c oxidase. Discov Med (2011) 1.02

Low-level laser therapy rescues dendrite atrophy via upregulating BDNF expression: implications for Alzheimer's disease. J Neurosci (2013) 1.02

Potential for transcranial laser or LED therapy to treat stroke, traumatic brain injury, and neurodegenerative disease. Photomed Laser Surg (2011) 1.00

Low-level laser therapy (LLLT) reduces oxidative stress in primary cortical neurons in vitro. J Biophotonics (2012) 0.99

Effects of low power laser irradiation on intracellular calcium and histamine release in RBL-2H3 mast cells. Photochem Photobiol (2007) 0.99

Augmentation of cognitive brain functions with transcranial lasers. Front Syst Neurosci (2014) 0.98

The brain effects of laser acupuncture in healthy individuals: an FMRI investigation. PLoS One (2010) 0.98

Low level laser therapy increases angiogenesis in a model of ischemic skin flap in rats mediated by VEGF, HIF-1α and MMP-2. J Photochem Photobiol B (2013) 0.98

Low-level light therapy improves cortical metabolic capacity and memory retention. J Alzheimers Dis (2012) 0.98

Phosphoinositide regulation of TRP channels. Handb Exp Pharmacol (2014) 0.97

Where in the brain is depression? Curr Psychiatry Rep (2012) 0.97

The contribution of astrocytes and microglia to traumatic brain injury. Br J Pharmacol (2015) 0.95

LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3beta-inactivation mechanism. J Cell Physiol (2010) 0.95

The impact of near-infrared light on dopaminergic cell survival in a transgenic mouse model of parkinsonism. Brain Res (2013) 0.94

Drug therapy in stroke: from preclinical to clinical studies. Pharmacology (2013) 0.93

Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain? Neuropsychiatr Dis Treat (2015) 0.93

Photobiomodulation inside the brain: a novel method of applying near-infrared light intracranially and its impact on dopaminergic cell survival in MPTP-treated mice. J Neurosurg (2013) 0.92

TRP channels: molecular diversity and physiological function. Microcirculation (2006) 0.92

Transcranial low level laser (light) therapy for traumatic brain injury. J Biophotonics (2012) 0.91

Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue. Lasers Surg Med (2015) 0.91

Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism - an abscopal neuroprotective effect. Neuroscience (2014) 0.91

Low-level laser therapy (808 nm) contributes to muscle regeneration and prevents fibrosis in rat tibialis anterior muscle after cryolesion. Lasers Med Sci (2012) 0.90

Tumoricidal effect of laser energy on experimental and human malignant tumors. N Engl J Med (1965) 0.89

Transcranial red and near infrared light transmission in a cadaveric model. PLoS One (2012) 0.89

Treatments for traumatic brain injury with emphasis on transcranial near-infrared laser phototherapy. Neuropsychiatr Dis Treat (2015) 0.89

Low-level laser therapy (810 nm) protects primary cortical neurons against excitotoxicity in vitro. J Biophotonics (2013) 0.88

Low-level laser therapy ameliorates disease progression in a mouse model of Alzheimer's disease. J Mol Neurosci (2014) 0.88

Photobiomodulation with near infrared light mitigates Alzheimer's disease-related pathology in cerebral cortex - evidence from two transgenic mouse models. Alzheimers Res Ther (2014) 0.88

NeuroThera® Efficacy and Safety Trial-3 (NEST-3): a double-blind, randomized, sham-controlled, parallel group, multicenter, pivotal study to assess the safety and efficacy of transcranial laser therapy with the NeuroThera® Laser System for the treatment of acute ischemic stroke within 24 h of stroke onset. Int J Stroke (2012) 0.87

Differential brain effects of laser and needle acupuncture at LR8 using functional MRI. Acupunct Med (2013) 0.87

Activated ERK/FOXM1 pathway by low-power laser irradiation inhibits UVB-induced senescence through down-regulating p21 expression. J Cell Physiol (2014) 0.87

Shedding light on a new treatment for diabetic wound healing: a review on phototherapy. ScientificWorldJournal (2014) 0.85

Stimulation of TRPV1 by Green Laser Light. Evid Based Complement Alternat Med (2012) 0.85

Photobiomodulation preserves behaviour and midbrain dopaminergic cells from MPTP toxicity: evidence from two mouse strains. BMC Neurosci (2013) 0.84

Transcranial low-level laser therapy enhances learning, memory, and neuroprogenitor cells after traumatic brain injury in mice. J Biomed Opt (2014) 0.84

Near-Infrared Transcranial Radiation for Major Depressive Disorder: Proof of Concept Study. Psychiatry J (2015) 0.83

Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis. Neurophotonics (2016) 0.82

Photobiomodulation by low-power laser irradiation attenuates Aβ-induced cell apoptosis through the Akt/GSK3β/β-catenin pathway. Free Radic Biol Med (2012) 0.82

The ligand binding battle at cytochrome c oxidase: how NO regulates oxygen gradients in tissue. Circ Res (2009) 0.82

Laser modulation of heat and capsaicin receptor TRPV1 leads to thermal antinociception. J Dent Res (2010) 0.81

Modulation of lipopolysaccharide-induced NF-κB signaling pathway by 635 nm irradiation via heat shock protein 27 in human gingival fibroblast cells. Photochem Photobiol (2012) 0.81

Effects of a higher dose of near-infrared light on clinical signs and neuroprotection in a monkey model of Parkinson's disease. Brain Res (2016) 0.80

Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy. IEEE J Sel Top Quantum Electron (2017) 0.79

The Antidepressant Effect of Laser Acupuncture: A Comparison of the Resting Brain's Default Mode Network in Healthy and Depressed Subjects During Functional Magnetic Resonance Imaging. Med Acupunct (2013) 0.79

Olfactory mucosa: a rich source of cell therapy for central nervous system repair. Rev Neurosci (2015) 0.79

Laser acupuncture improves memory impairment in an animal model of Alzheimer's disease. J Acupunct Meridian Stud (2013) 0.79

Temperature sensing by thermal TRP channels: thermodynamic basis and molecular insights. Curr Top Membr (2014) 0.78

Harvesting blood stem cells from cranial bone at craniotomy--a preliminary study. J Neurooncol (2003) 0.78

Current pharmacotherapy and putative disease-modifying therapy for Alzheimer's disease. Neurol Sci (2016) 0.77

Multi-watt near-infrared light therapy as a neuroregenerative treatment for traumatic brain injury. Neural Regen Res (2016) 0.77

Laser Acupuncture Improves Behavioral Disorders and Brain Oxidative Stress Status in the Valproic Acid Rat Model of Autism. J Acupunct Meridian Stud (2015) 0.77

Near infrared light mitigates cerebellar pathology in transgenic mouse models of dementia. Neurosci Lett (2015) 0.77

Targeting the body to protect the brain: inducing neuroprotection with remotely-applied near infrared light. Neural Regen Res (2015) 0.77

Oxidative stress, protein modification and Alzheimer disease. Brain Res Bull (2016) 0.77

Low-Level Laser Therapy to the Bone Marrow Ameliorates Neurodegenerative Disease Progression in a Mouse Model of Alzheimer's Disease: A Minireview. Photomed Laser Surg (2016) 0.76

Transcranial Near-Infrared Laser Therapy for Stroke: How to Recover from Futility in the NEST-3 Clinical Trial. Acta Neurochir Suppl (2016) 0.76

The role of oxidative and nitrosative stress in accelerated aging and major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry (2015) 0.76

Near-infrared light treatment reduces astrogliosis in MPTP-treated monkeys. Exp Brain Res (2016) 0.76

Cardiovascular side effects of psychopharmacologic therapy. Int J Cardiol (2016) 0.76

Increases in microvascular perfusion and tissue oxygenation via pulsed electromagnetic fields in the healthy rat brain. J Neurosurg (2014) 0.76

Light pumping energy into blood mitochondria: a new trend against depression? Photomed Laser Surg (2014) 0.76

Vascular Contributions in Alzheimer's Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population. J Alzheimers Dis (2016) 0.75

Synapsins Are Downstream Players of the BDNF-Mediated Axonal Growth. Mol Neurobiol (2016) 0.75