Assessment of renal hemodynamic toxicity of fluid challenge with 0.9% NaCl compared to balanced crystalloid (PlasmaLyte(®)) in a rat model with severe sepsis.

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Published in Ann Intensive Care on June 14, 2017

Authors

Pierre-Yves Olivier1,2,3, François Beloncle1,2,3, Valérie Seegers1,4, Maher Tabka3,5, Mathilde Renou de La Bourdonnaye3,5, Alain Mercat1,2, Paul Cales1,6, Daniel Henrion3,5, Peter Radermacher7,8, Lise Piquilloud1,2, Nicolas Lerolle1,2,3, Pierre Asfar9,10,11

Author Affiliations

1: CHU d'Angers, 4 rue Larrey, 49000, Angers, France.
2: Medical Intensive Care Department, University Hospital, Angers, France.
3: BNMI Laboratory, CNRS UMR 6214-INSERM U1083, Angers University, Angers, France.
4: Statistical Department, University Hospital, Angers, France.
5: Faculté de médecine d'Angers, 4 rue haute de reculée, 49000, Angers, France.
6: HIFIH, UPRE-EA 3859, SFR 4208, LUNAM University, Angers, France.
7: Universitätsklinikum, Ulm Helmholtzstr. 8/1, 89081, Ulm, Germany.
8: Institut für Anästhesiologische Pathophysiologie und Verfahrensentwicklung, Universitätsklinikum, Ulm, Germany.
9: CHU d'Angers, 4 rue Larrey, 49000, Angers, France. piasfar@chu-angers.fr.
10: Medical Intensive Care Department, University Hospital, Angers, France. piasfar@chu-angers.fr.
11: BNMI Laboratory, CNRS UMR 6214-INSERM U1083, Angers University, Angers, France. piasfar@chu-angers.fr.

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