Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study.

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🔗 View Article (PMID 28646893)

Published in J Transl Med on June 24, 2017

Authors

Luis de la Cruz-Merino1, Lorenza Di Guardo2, Jean-Jacques Grob3, Alfredo Venosa4, James Larkin5, Grant A McArthur6,7, Antoni Ribas8, Paolo A Ascierto9, Jeffrey T R Evans10, Antonio Gomez-Escobar11, Giulio Barteselli12, Susan Eng12, Jessie J Hsu12, Anne Uyei12, Brigitte Dréno13

Author Affiliations

1: Servicio de Oncología Médica, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41071, Seville, Spain. lucme12@yahoo.es.
2: Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
3: Aix-Marseille University, Hôpital de la Timone, Marseille, France.
4: Ospedale Monaldi, Naples, Italy.
5: Royal Marsden NHS Foundation Trust, London, UK.
6: Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.
7: University of Melbourne, Parkville, VIC, Australia.
8: Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, CA, USA.
9: Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy.
10: Beatson West of Scotland Cancer Centre, University of Glasgow, Glasgow, UK.
11: Servicio de Oncología Médica, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41071, Seville, Spain.
12: Genentech, Inc., South San Francisco, CA, USA.
13: Nantes University, Nantes, France.

Associated clinical trials:

A Phase III Study Comparing Vemurafenib vs Vemurafenib Plus Cobimetinib (GDC-0973) in Patients With Metastatic Melanoma (coBRIM) | NCT01689519

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