Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma.

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Published in Eur Urol on August 07, 2017

Authors

Mitchell J Machiela1, Jonathan N Hofmann1, Robert Carreras-Torres2, Kevin M Brown1, Mattias Johansson2, Zhaoming Wang3, Matthieu Foll2, Peng Li2, Nathaniel Rothman1, Sharon A Savage1, Valerie Gaborieau2, James D McKay2, Yuanqing Ye4, Marc Henrion5, Fiona Bruinsma6, Susan Jordan7, Gianluca Severi8, Kristian Hveem9, Lars J Vatten10, Tony Fletcher11, Kvetoslava Koppova12, Susanna C Larsson13, Alicja Wolk13, Rosamonde E Banks14, Peter J Selby14, Douglas F Easton15, Paul Pharoah15, Gabriella Andreotti1, Laura E Beane Freeman1, Stella Koutros1, Demetrius Albanes1, Satu Mannisto16, Stephanie Weinstein1, Peter E Clark17, Todd E Edwards17, Loren Lipworth17, Susan M Gapstur18, Victoria L Stevens18, Hallie Carol19, Matthew L Freedman19, Mark M Pomerantz19, Eunyoung Cho20, Peter Kraft21, Mark A Preston22, Kathryn M Wilson21, J Michael Gaziano23, Howard S Sesso21, Amanda Black1, Neal D Freedman1, Wen-Yi Huang1, John G Anema24, Richard J Kahnoski24, Brian R Lane25, Sabrina L Noyes26, David Petillo26, Leandro M Colli1, Joshua N Sampson1, Celine Besse27, Helene Blanche28, Anne Boland27, Laurie Burdette1, Egor Prokhortchouk29, Konstantin G Skryabin29, Meredith Yeager1, Mirjana Mijuskovic30, Miodrag Ognjanovic31, Lenka Foretova31, Ivana Holcatova32, Vladimir Janout33, Dana Mates34, Anush Mukeriya35, Stefan Rascu36, David Zaridze35, Vladimir Bencko37, Cezary Cybulski38, Eleonora Fabianova12, Viorel Jinga37, Jolanta Lissowska39, Jan Lubinski40, Marie Navratilova32, Peter Rudnai41, Neonila Szeszenia-Dabrowska42, Simone Benhamou43, Geraldine Cancel-Tassin44, Olivier Cussenot45, H Bas Bueno-de-Mesquita46, Federico Canzian47, Eric J Duell48, Börje Ljungberg49, Raviprakash T Sitaram49, Ulrike Peters50, Emily White50, Garnet L Anderson50, Lisa Johnson50, Juhua Luo51, Julie Buring21, I-Min Lee52, Wong-Ho Chow4, Lee E Moore1, Christopher Wood53, Timothy Eisen54, James Larkin55, Toni K Choueiri19, G Mark Lathrop56, Bin Tean Teh26, Jean-Francois Deleuze57, Xifeng Wu4, Richard S Houlston58, Paul Brennan2, Stephen J Chanock1, Ghislaine Scelo2, Mark P Purdue59

Author Affiliations

1: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MS, USA.
2: International Agency for Research on Cancer (IARC), Lyon, France.
3: St. Jude Children's Research Hospital, Memphis, TN, USA.
4: Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
5: Icahn School of Medicine, New York, NY, USA.
6: Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Australia.
7: QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia; School of Public Health, The University of Queensland, Brisbane, Australia.
8: Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, Australia; Human Genetics Foundation (HuGeF), Torino, Italy; Centre de Recherche en Épidémiologie et Santé des Populations, Université Paris-Saclay, UPS, USQ, Gustave Roussy, Villejuif, France.
9: HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Sweden.
10: Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
11: London School of Hygiene and Tropical Medicine, University of London, London, UK.
12: Regional Authority of Public Health in Banska Bystrica, Banska Bystrica, Slovakia.
13: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
14: Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds, UK.
15: Department of Oncology, and Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
16: National Institute for Health and Welfare, Helsinki, Finland.
17: Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
18: American Cancer Society, Atlanta, GA, USA.
19: Dana-Farber Cancer Institute, Boston, MA, USA.
20: Brown University, Providence, RI, USA.
21: Harvard T.H. Chan School of Public Health, Boston, MA, USA.
22: Brigham and Women's Hospital, Boston, MA, USA.
23: Brigham and Women's Hospital, Boston, MA, USA; Veterans Administration, Boston, MA, USA.
24: Division of Urology, Spectrum Health, Grand Rapids, MI, USA.
25: Division of Urology, Spectrum Health, Grand Rapids, MI, USA; College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.
26: Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, MI, USA.
27: Centre National de Recherche en Genomique Humaine (CNRGH), Institut de biologie François Jacob, Commissariat à l'Energie Atomique et aux Energies Alternatives, Evry, France.
28: Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, Paris, France.
29: Center 'Bioengineering' of the Russian Academy of Sciences, Moscow, Russian Federation; Kurchatov Scientific Center, Moscow, Russian Federation.
30: Clinic for Nephrology, Military Medical Academy, Belgrade, Serbia.
31: International Organization for Cancer Prevention and Research (IOCPR), Belgrade, Serbia.
32: Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
33: Second Faculty of Medicine, Institute of Public Health and Preventive Medicine, Charles University, Prague, Czech Republic.
34: Department of Preventive Medicine, Faculty of Medicine, Palacky University, Czech Republic.
35: National Institute of Public Health, Bucharest, Romania.
36: Russian N.N. Blokhin Cancer Research Centre, Moscow, Russian Federation.
37: Carol Davila University of Medicine and Pharmacy, Th. Burghele Hospital, Bucharest, Romania.
38: First Faculty of Medicine, Institute of Hygiene and Epidemiology, Charles University, Prague, Czech Republic.
39: The M Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland.
40: International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
41: National Public Health Center, National Directorate of Environmental Health, Budapest, Hungary.
42: Department of Epidemiology, Institute of Occupational Medicine, Lodz, Poland.
43: INSERM U946, Paris, France; CNRS UMR8200, Institute Gustave Roussy, Villejuif, France.
44: CeRePP, Paris, France; UPMC Univ Paris 06, Institut Universitaire de Cancérologie, Paris, France.
45: CeRePP, Paris, France; UPMC Univ Paris 06, Institut Universitaire de Cancérologie, Paris, France; AP-HP, Department of Urology, Hopitaux Universitaires Est Parisien Tenon, Paris, France.
46: Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands; Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, St Mary's Campus, Norfolk Place, London, UK; Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Pantai Valley, Kuala Lumpur, Malaysia.
47: Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
48: Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain.
49: Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden.
50: Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
51: Department of Epidemiology and Biostatistics, School of Public Health Indiana University Bloomington, Bloomington, IN, USA.
52: Harvard T.H. Chan School of Public Health, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA.
53: Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
54: University of Cambridge, Cambridge, UK.
55: Royal Marsden NHS Foundation Trust, London, UK.
56: McGill University and Genome Quebec Innovation Centre, Montreal, QC, Canada.
57: Centre National de Recherche en Genomique Humaine (CNRGH), Institut de biologie François Jacob, Commissariat à l'Energie Atomique et aux Energies Alternatives, Evry, France; Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, Paris, France.
58: The Institute of Cancer Research, London, UK.
59: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MS, USA. Electronic address: purduem@mail.nih.gov.

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