Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28680364)

Published in Proteome Sci on July 01, 2017

Authors

Michael P Gotsbacher1,2, Sungmin Cho3, Ho Jeong Kwon3, Peter Karuso1

Author Affiliations

1: Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109 Australia.
2: Present address: School of Medical Sciences (Pharmacology), The University of Sydney, Sydney, NSW 2006 Australia.
3: Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-749 South Korea.

Articles cited by this

How many drug targets are there? Nat Rev Drug Discov (2006) 14.22

Cu-catalyzed azide-alkyne cycloaddition. Chem Rev (2008) 6.21

Global mapping of pharmacological space. Nat Biotechnol (2006) 4.99

Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia. Am J Hum Genet (2006) 3.17

Daptomycin: a novel agent for Gram-positive infections. Expert Opin Investig Drugs (1999) 2.83

Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia. Hum Mutat (2007) 2.73

Structural transitions as determinants of the action of the calcium-dependent antibiotic daptomycin. Chem Biol (2004) 2.51

Lipoteichoic acid as a new target for activity of antibiotics: mode of action of daptomycin (LY146032). Antimicrob Agents Chemother (1990) 2.40

Target identification using drug affinity responsive target stability (DARTS). Proc Natl Acad Sci U S A (2009) 2.40

Localisation of DivIVA by targeting to negatively curved membranes. EMBO J (2009) 2.35

Transcriptional profiling reveals that daptomycin induces the Staphylococcus aureus cell wall stress stimulon and genes responsive to membrane depolarization. Antimicrob Agents Chemother (2007) 2.27

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits. Blood (2006) 2.22

Impaired ribosome biogenesis in Diamond-Blackfan anemia. Blood (2006) 2.16

Negative membrane curvature as a cue for subcellular localization of a bacterial protein. Proc Natl Acad Sci U S A (2009) 2.12

Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantation. Mol Cell Biol (2004) 1.85

Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis. J Biol Chem (2005) 1.79

Severe myopathy and possible hepatotoxicity related to daptomycin. J Antimicrob Chemother (2005) 1.69

Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production. Blood Cells Mol Dis (2007) 1.68

In vitro bactericidal activities of daptomycin against Staphylococcus aureus and Enterococcus faecalis are not mediated by inhibition of lipoteichoic acid biosynthesis. Antimicrob Agents Chemother (2003) 1.41

Polypharmacology: challenges and opportunities in drug discovery. J Med Chem (2014) 1.35

A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation. J Antibiot (Tokyo) (1987) 1.29

Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains. Proc Natl Acad Sci U S A (2016) 1.19

Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class I messenger RNAs associated with colon carcinoma progression and differentiation. Cancer Res (1992) 1.18

The activity of daptomycin on Enterococcus faecium protoplasts: indirect evidence supporting a novel mode of action on lipoteichoic acid synthesis. J Antimicrob Chemother (1993) 1.17

Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. J Biol Chem (2010) 1.17

Oligomerization of daptomycin on membranes. Biochim Biophys Acta (2011) 1.16

Daptomycin: a review 4 years after first approval. Pharmacology (2007) 1.15

Daptomycin. Drugs (2004) 1.12

Diamond Blackfan anemia: A paradigm for a ribosome-based disease. Med Hypotheses (2005) 1.09

Biotin and biotin analogs in human urine: biotin accounts for only half of the total. J Nutr (1993) 1.01

Identification of daptomycin-binding proteins in the membrane of Enterococcus hirae. Antimicrob Agents Chemother (1995) 1.00

Quality, not quantity: the role of natural products and chemical proteomics in modern drug discovery. Comb Chem High Throughput Screen (2004) 0.98

Quantitation of the specific interaction of [14a-3H]cryptopleurine with 80S and 40S ribosomal species from the yeast Saccharomyces cerevisiae. Biochemistry (1982) 0.96

NMR structure determination and calcium binding effects of lipopeptide antibiotic daptomycin. Org Biomol Chem (2004) 0.93

A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function. Chem Biol (2004) 0.89

Rapid identification of a protein binding partner for the marine natural product kahalalide F by using reverse chemical proteomics. Chembiochem (2008) 0.83

Advances in identification and validation of protein targets of natural products without chemical modification. Nat Prod Rep (2016) 0.81

Array synthesis of novel lipodepsipeptide. Bioorg Med Chem Lett (2003) 0.80

Studies on the reactions between daptomycin and glyceraldehyde. Int J Pharm (2004) 0.79

Ribosome distribution in HeLa cells during the cell cycle. PLoS One (2012) 0.77

Effect of daptomycin on primary rat muscle cell cultures in vitro. In Vitro Cell Dev Biol Anim (2010) 0.77

Identifying the cellular targets of natural products using T7 phage display. Nat Prod Rep (2016) 0.77

Rapid isolation of novel FK506 binding proteins from multiple organisms using gDNA and cDNA T7 phage display. Bioorg Med Chem (2009) 0.76

FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells. J Proteome Res (2016) 0.76

The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis. Int J Biol Sci (2015) 0.76

Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun (2016) 0.76