Published in Temperature (Austin) on February 16, 2017
Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci (1998) 9.88
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell (1999) 9.84
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med (2000) 7.05
Sympathetic-nerve activity during sleep in normal subjects. N Engl J Med (1993) 5.85
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron (2001) 5.09
Sleep state switching. Neuron (2010) 4.94
The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci (2001) 4.33
Functional organization of central pathways regulating the cardiovascular system. Physiol Rev (1994) 3.65
Tuning arousal with optogenetic modulation of locus coeruleus neurons. Nat Neurosci (2010) 3.50
Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc Natl Acad Sci U S A (1999) 3.42
Activation of ventrolateral preoptic neurons during sleep. Science (1996) 3.27
Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J Comp Neurol (1990) 2.52
Attenuated defense response and low basal blood pressure in orexin knockout mice. Am J Physiol Regul Integr Comp Physiol (2003) 2.45
Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology (2005) 2.33
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J Comp Neurol (1999) 2.32
Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. J Neurosci (1998) 2.21
Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron (2005) 2.11
Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons. J Neurosci (2000) 2.05
Reassessment of the structural basis of the ascending arousal system. J Comp Neurol (2011) 1.93
Identification of sleep-promoting neurons in vitro. Nature (2000) 1.90
Afferents to the ventrolateral preoptic nucleus. J Neurosci (2002) 1.86
Paraventricular nucleus, stress response, and cardiovascular disease. Clin Auton Res (2005) 1.83
Elevated body temperature during sleep in orexin knockout mice. Am J Physiol Regul Integr Comp Physiol (2006) 1.71
Neuronal activity of histaminergic tuberomammillary neurons during wake-sleep states in the mouse. J Neurosci (2006) 1.65
Neuronal activity of orexin and non-orexin waking-active neurons during wake-sleep states in the mouse. Neuroscience (2008) 1.62
Skin temperature: its role in thermoregulation. Acta Physiol (Oxf) (2014) 1.43
Unitary characteristics of presumptive cholinergic tegmental neurons during the sleep-waking cycle in freely moving cats. Exp Brain Res (1989) 1.36
Skin deep: enhanced sleep depth by cutaneous temperature manipulation. Brain (2008) 1.34
Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. J Physiol (2007) 1.30
Effect of ambient temperature on cardiovascular parameters in rats and mice: a comparative approach. Am J Physiol Regul Integr Comp Physiol (2004) 1.30
Hypothalamic regulation of sleep and arousal. Ann N Y Acad Sci (2008) 1.29
Functional link between distal vasodilation and sleep-onset latency? Am J Physiol Regul Integr Comp Physiol (2000) 1.24
The regulation of heart rate during sleep. Exp Brain Res (1969) 1.23
Locus coeruleus neuronal activity during the sleep-waking cycle in mice. Neuroscience (2010) 1.21
Modulation of carotid sinus afferent input to nucleus tractus solitarius by parabrachial nucleus stimulation. Circ Res (1988) 1.19
Locomotion-inducing sites in the vicinity of the pedunculopontine nucleus. Brain Res Bull (1987) 1.14
Sleep related changes in blood pressure in hypocretin-deficient narcoleptic mice. Sleep (2011) 1.13
Hemodynamic changes during sleep. J Appl Physiol (1967) 1.11
Spinal projections of the A5, A6 (locus coeruleus), and A7 noradrenergic cell groups in rats. J Comp Neurol (2012) 1.06
Abnormal sleep-cardiovascular system interaction in narcolepsy with cataplexy: effects of hypocretin deficiency in humans. Sleep (2012) 1.06
Characterization and mapping of sleep-waking specific neurons in the basal forebrain and preoptic hypothalamus in mice. Neuroscience (2009) 1.06
Altered skin-temperature regulation in narcolepsy relates to sleep propensity. Sleep (2006) 1.05
Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice. Am J Physiol Regul Integr Comp Physiol (2006) 1.04
Glutamatergic signaling from the parabrachial nucleus plays a critical role in hypercapnic arousal. J Neurosci (2013) 1.02
Parabrachial nucleus projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol (2000) 1.02
The median preoptic nucleus: front and centre for the regulation of body fluid, sodium, temperature, sleep and cardiovascular homeostasis. Acta Physiol (Oxf) (2015) 1.00
Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins. J Appl Physiol (1985) (2010) 0.99
On the functional significance of c-fos induction during the sleep-waking cycle. Sleep (2000) 0.98
Physiological sleep-dependent changes in arterial blood pressure: central autonomic commands and baroreflex control. Clin Exp Pharmacol Physiol (2008) 0.98
Diverse afferents converge on the nucleus paragigantocellularis in the rat ventrolateral medulla: retrograde and anterograde tracing studies. J Comp Neurol (1989) 0.98
Cardiovascular and respiratory effects of stimulation of cell bodies of the parabrachial nuclei in the anaesthetized rat. J Physiol (1994) 0.95
Central neural control of thermoregulation and brown adipose tissue. Auton Neurosci (2016) 0.95
Effects of ambient temperature on sleep and cardiovascular regulation in mice: the role of hypocretin/orexin neurons. PLoS One (2012) 0.95
Sleep, vigilance, and thermosensitivity. Pflugers Arch (2011) 0.95
Sleep-active neurons in the preoptic area project to the hypothalamic paraventricular nucleus and perifornical lateral hypothalamus. Eur J Neurosci (2006) 0.93
Independent vasomotor control of rat tail and proximal hairy skin. J Physiol (2007) 0.93
Non-dipping blood pressure profile in narcolepsy with cataplexy. PLoS One (2012) 0.92
Relationship between renal sympathetic nerve activity and arterial pressure during REM sleep in rats. Am J Physiol Regul Integr Comp Physiol (2002) 0.91
Central command regulation of circulatory function mediated by descending pontine cholinergic inputs to sympathoexcitatory rostral ventrolateral medulla neurons. Circ Res (2007) 0.90
Brain and core temperatures and peripheral vasomotion during sleep and wakefulness at various ambient temperatures in the rat. Pflugers Arch (1990) 0.90
Vasomotor regulation during sleep in the cat. Am J Physiol (1971) 0.90
Sleep-promoting functions of the hypothalamic median preoptic nucleus: inhibition of arousal systems. Arch Ital Biol (2004) 0.89
Thermoeffector neuronal pathways in fever: a study in rats showing a new role of the locus coeruleus. J Physiol (2004) 0.89
Manipulation of core body and skin temperature improves vigilance and maintenance of wakefulness in narcolepsy. Sleep (2008) 0.88
Modulation of thalamic neuron excitability by orexins. Neuropharmacology (2006) 0.88
Arousal responses to hypertension in lambs: effect of sinoaortic denervation. Am J Physiol (1991) 0.87
Nitric oxide inhibition abolishes sleep-wake differences in cerebral circulation. Am J Physiol Heart Circ Physiol (2001) 0.86
Central control of cardiovascular function during sleep. Am J Physiol Heart Circ Physiol (2013) 0.86
Relationship between renal sympathetic nerve activity and renal blood flow during natural behavior in rats. Am J Physiol Regul Integr Comp Physiol (2004) 0.85
Sleep-related changes in human muscle and skin sympathetic nerve activities. J Auton Nerv Syst (1994) 0.85
Sleep-dependent changes in cerebral oxygen consumption in newborn lambs. J Sleep Res (2006) 0.84
Sleep and cardiovascular phenotype in middle-aged hypocretin-deficient narcoleptic mice. J Sleep Res (2013) 0.84
Attenuated cold defense responses in orexin neuron-ablated rats. Temperature (Austin) (2016) 0.84
Blood flow and oxygen uptake in the human brain during various states of sleep and wakefulness. Acta Neurol Scand Suppl (1993) 0.83
Waking up properly: is there a role of thermoregulation in sleep inertia? J Sleep Res (2004) 0.83
Midbrain modulation of the cardiac baroreflex involves excitation of lateral parabrachial neurons in the rat. Brain Res (2007) 0.83
Glutamatergic lateral parabrachial neurons innervate orexin-containing hypothalamic neurons in the rat. Brain Res (2010) 0.83
SCOPRISM: a new algorithm for automatic sleep scoring in mice. J Neurosci Methods (2014) 0.83
Differential effects of sleep stage on coronary hemodynamic function. Am J Physiol (1989) 0.82
Diurnal blood pressure variations are associated with changes in distal-proximal skin temperature gradient. Chronobiol Int (2012) 0.81
Systemic and pulmonary hemodynamic responses to normal and obstructed breathing during sleep. J Appl Physiol (1985) (1997) 0.81
Convergence of sleep-wakefulness subsystems onto single neurons in the region of cat's solitary tract nucleus. Arch Ital Biol (1980) 0.81
Brain-heart interactions: physiology and clinical implications. Philos Trans A Math Phys Eng Sci (2016) 0.81
Hypocretin deficiency in narcolepsy with cataplexy is associated with a normal body core temperature modulation. Chronobiol Int (2010) 0.80
The role of the baroreceptors and of blood pressure in the regulation of sleep and wakefulness. Exp Brain Res (1967) 0.80
Discharge patterns of the nucleus parabrachialis lateralis neurons of the cat during sleep and waking. Brain Res (1977) 0.80
Time- and state-dependent analysis of autonomic control in narcolepsy: higher heart rate with normal heart rate variability independent of sleep fragmentation. J Sleep Res (2014) 0.80
Drug-induced arterial pressure elevation is associated with arousal from NREM sleep in normal volunteers. J Appl Physiol (1985) (1999) 0.80
Promotion of Wakefulness and Energy Expenditure by Orexin-A in the Ventrolateral Preoptic Area. Sleep (2015) 0.79
Hubs and spokes of the lateral hypothalamus: cell types, circuits and behaviour. J Physiol (2016) 0.79
Sleep-waking discharge profiles of median preoptic and surrounding neurons in mice. Neuroscience (2011) 0.78
Attenuation of regional differentiation of sympathetic nerve activity during sleep in humans. J Auton Nerv Syst (1998) 0.78
Lower wake resting sympathetic and cardiovascular activities in narcolepsy with cataplexy. Neurology (2014) 0.78
Sympathetic and cardiovascular changes during sleep in narcolepsy with cataplexy patients. Sleep Med (2014) 0.78
Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice. PLoS One (2013) 0.77
Orexin/hypocretin system and autonomic control: new insights and clinical correlations. Neurology (2013) 0.77
The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy. J Sleep Res (2015) 0.77
A restricted parabrachial pontine region is active during non-rapid eye movement sleep. Neuroscience (2011) 0.76
Differential regional hemodynamic changes produced by L-glutamate stimulation of the locus coeruleus. Brain Res (1993) 0.76
Cardiovascular variability as a function of sleep-wake behaviour in narcolepsy with cataplexy. J Sleep Res (2012) 0.76
Short-interval leg movements during sleep entail greater cardiac activation than periodic leg movements during sleep in restless legs syndrome patients. J Sleep Res (2017) 0.75
Commentary: Coordinated infraslow neural and cardiac oscillations mark fragility and offline periods in mammalian sleep. Front Physiol (2017) 0.75
CDKL5 deficiency entails sleep apneas in mice. J Sleep Res (2017) 0.75