Published in Elife on July 12, 2017
Genome-wide atlas of gene expression in the adult mouse brain. Nature (2006) 28.02
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature (2003) 16.48
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci (1999) 12.50
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci (1996) 9.84
Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci (2005) 7.14
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nat Immunol (2005) 6.49
Milestones of neuronal development in the adult hippocampus. Trends Neurosci (2004) 5.80
Astrocytes give rise to new neurons in the adult mammalian hippocampus. J Neurosci (2001) 5.66
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods (2005) 5.59
Notch signalling regulates stem cell numbers in vitro and in vivo. Nature (2006) 5.49
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell (2009) 5.33
In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell (2007) 5.32
Neural stem and progenitor cells in nestin-GFP transgenic mice. J Comp Neurol (2004) 5.22
Notch signalling in vertebrate neural development. Nat Rev Neurosci (2006) 4.97
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet (1999) 4.55
Agouti-related peptide-expressing neurons are mandatory for feeding. Nat Neurosci (2005) 4.44
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell (2010) 4.30
Fringe is a glycosyltransferase that modifies Notch. Nature (2000) 4.09
Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus. Cell Stem Cell (2011) 4.08
Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron (2000) 3.70
Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng (1999) 3.65
Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron (2008) 3.51
In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics. Cell (2011) 3.47
Maintenance of somite borders in mice requires the Delta homologue DII1. Nature (1997) 3.44
Fluoxetine targets early progenitor cells in the adult brain. Proc Natl Acad Sci U S A (2006) 3.39
Notch signaling: simplicity in design, versatility in function. Development (2011) 3.13
Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus (2006) 3.02
Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli. J Comp Neurol (2003) 3.02
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell (2010) 2.79
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet (2006) 2.56
Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. Science (2013) 2.56
Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci (2010) 2.55
Increased neurogenesis in a model of electroconvulsive therapy. Biol Psychiatry (2000) 2.48
Glycosylation regulates Notch signalling. Nat Rev Mol Cell Biol (2003) 2.48
Defects in somite formation in lunatic fringe-deficient mice. Nature (1998) 2.37
Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J (1994) 2.35
Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A (2007) 2.31
Experience dictates stem cell fate in the adult hippocampus. Neuron (2011) 2.18
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol (2016) 2.15
Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate. Neuron (2001) 2.06
Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis. Cell Stem Cell (2015) 1.84
RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci (2010) 1.76
The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells. J Neurosci (2000) 1.74
Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells. J Neurosci (2010) 1.72
Identifying and quantitating neural stem and progenitor cells in the adult brain. Methods Cell Biol (2008) 1.72
Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1. Mol Biol Cell (2004) 1.71
Notch1 is required for neuronal and glial differentiation in the cerebellum. Development (2002) 1.69
Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors. Development (2012) 1.55
Increased generation of granule cells in adult Bcl-2-overexpressing mice: a role for cell death during continued hippocampal neurogenesis. Eur J Neurosci (2005) 1.53
Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol (2010) 1.51
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum. Proc Natl Acad Sci U S A (2007) 1.47
Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus. Proc Natl Acad Sci U S A (2008) 1.46
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. Cancer Cell (2012) 1.44
Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling. Dev Cell (2002) 1.44
Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells. J Neurosci (2010) 1.41
Posttraining ablation of adult-generated neurons degrades previously acquired memories. J Neurosci (2011) 1.41
Roles of glycosylation in Notch signaling. Curr Top Dev Biol (2010) 1.30
Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors. Development (2001) 1.20
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol (2009) 1.12
Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands. Proc Natl Acad Sci U S A (2014) 1.06
Neurogenic subventricular zone stem/progenitor cells are Notch1-dependent in their active but not quiescent state. J Neurosci (2012) 1.01
Notching up neural stem cell homogeneity in homeostasis and disease. Front Neurosci (2014) 1.01
Physical exercise increases Notch activity, proliferation and cell cycle exit of type-3 progenitor cells in adult hippocampal neurogenesis. Eur J Neurosci (2010) 1.00
Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development (2013) 0.92
Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions. Development (2014) 0.92
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. Elife (2014) 0.92
Notch signal strength controls cell fate in the haemogenic endothelium. Nat Commun (2015) 0.90
Expression of fringe is down regulated by Gurken/Epidermal Growth Factor Receptor signalling and is required for the morphogenesis of ovarian follicle cells. J Cell Sci (2000) 0.90
Lunatic fringe promotes the lateral inhibition of neurogenesis. Development (2009) 0.88
Brief report: Adult hippocampal precursor cells shorten S-phase and total cell cycle length during neuronal differentiation. Stem Cells (2012) 0.86
Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis. Neurobiol Dis (2014) 0.81
Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus. Dev Biol (2014) 0.80
Aging Neural Progenitors Lose Competence to Respond to Mitogenic Notch Signaling. Curr Biol (2015) 0.79
Transgenic mouse models for studying adult neurogenesis. Front Biol (Beijing) (2016) 0.78
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife (2016) 0.78
Excess lunatic fringe causes cranial neural crest over-proliferation. Dev Biol (2001) 0.76
SPOT14-positive neural stem/progenitor cells in the hippocampus respond dynamically to neurogenic regulators. Stem Cell Reports (2014) 0.76