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S Sassa

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1 Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition. J Biol Chem 1975 2.47
2 Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells. J Exp Med 1976 2.36
3 Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J 2001 2.32
4 Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nat Genet 1998 1.98
5 Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation. J Biol Chem 1982 1.83
6 Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process. J Biol Chem 1977 1.83
7 Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture. Proc Natl Acad Sci U S A 1970 1.77
8 Assays for porphyrins, delta-aminolevulinic-acid dehydratase, and porphyrinogen synthetase in microliter samples of whole blood: applications to metabolic defects involving the heme pathway. Proc Natl Acad Sci U S A 1972 1.77
9 Prevention of cyclical attacks of acute intermittent porphyria with a long-acting agonist of luteinizing hormone-releasing hormone. N Engl J Med 1984 1.68
10 A zebrafish model for hepatoerythropoietic porphyria. Nat Genet 1998 1.62
11 Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines. J Lab Clin Med 1992 1.58
12 Porphyria cutanea tarda associated with the acquired immune deficiency syndrome. Am J Hematol 1987 1.57
13 Studies in lead poisoning. I. Microanalysis of erythrocyte protoporphyrin levels by spectrophotometry in the detection of chronic lead intoxication in the subclinical range. Biochem Med 1973 1.53
14 Lead binding to delta-aminolevulinic acid dehydratase (ALAD) in human erythrocytes. Pharmacol Toxicol 1997 1.50
15 Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III. J Biol Chem 1983 1.50
16 Delta-aminolevulinic acid dehydratase assay. Enzyme 1982 1.49
17 A microassay for uroporphyrinogen I synthase, one of three abnormal enzyme activities in acute intermittent porphyria, and its application to the study of the genetics of this disease. Proc Natl Acad Sci U S A 1974 1.48
18 Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis. J Biol Chem 1979 1.39
19 Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries. Curr Med Chem 2004 1.36
20 Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures. Biochem J 1986 1.35
21 Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. Blood 1993 1.25
22 Effect of lead and genetic factors on heme biosynthesis in the human red cell. Ann N Y Acad Sci 1975 1.24
23 Hereditary tyrosinemia and the heme biosynthetic pathway. Profound inhibition of delta-aminolevulinic acid dehydratase activity by succinylacetone. J Clin Invest 1983 1.22
24 Heme biosynthesis in bacterium-protozoon symbioses: enzymic defects in host hemoflagellates and complemental role of their intracellular symbiotes. Proc Natl Acad Sci U S A 1975 1.22
25 Biochemical studies of a patient with hereditary hepatorenal tyrosinemia: evidence of glutathione deficiency. Pediatr Res 1984 1.20
26 Studies in lead poisoning. II. Correlation between the ratio of activated to inactivated delta-aminolevulinic acid dehydratase of whole blood and the blood lead level. Biochem Med 1973 1.19
27 Tumor promoter-mediated inhibition of cell differentiation: suppression of the expression of erythroid functions in murine erythroleukemia cells. Proc Natl Acad Sci U S A 1979 1.18
28 Regulation of NF-E2 activity in erythroleukemia cell differentiation. J Biol Chem 1998 1.15
29 Tin-protoporphyrin suppression of hyperbilirubinemia in mutant mice with severe hemolytic anemia. Blood 1983 1.15
30 Effects of polychlorinated biphenyl compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phenobarbital and iron on hepatic uroporphyrinogen decarboxylase. Implications for the pathogenesis of porphyria. Biochem J 1983 1.15
31 Studies in porphyria. IV. Expression of the gene defect of acute intermittent porphyria in cultured human skin fibroblasts and amniotic cells: prenatal diagnosis of the porphyric trait. J Exp Med 1975 1.14
32 Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload. EMBO J 1999 1.14
33 Drug metabolism in normal children, lead-poisoned children, and normal adults. Clin Pharmacol Ther 1975 1.12
34 Inhibition of dimethyl sulfoxide-stimulated Friend cell erythrodifferentiation by hydrocortisone and other steroids. Proc Natl Acad Sci U S A 1978 1.11
35 Drug metabolism by the human hepatoma cell, Hep G2. Biochem Biophys Res Commun 1987 1.11
36 The occurrence of substances in human plasma capable of inducing the enzyme delta-aminolevulinate synthetase in liver cells. Proc Natl Acad Sci U S A 1969 1.11
37 Erythroleukemia differentiation. Distinctive responses of the erythroid-specific and the nonspecific delta-aminolevulinate synthase mRNA. J Biol Chem 1991 1.10
38 Genetic, metabolic, and biochemical aspects of the porphyrias. Adv Hum Genet 1981 1.10
39 A novel MPL point mutation resulting in thrombopoietin-independent activation. Leukemia 2002 1.10
40 The origin of the increased protoporphyrin in erythrocytes of mice with experimentally induced porphyria. J Lab Clin Med 1967 1.06
41 Studies in porphyria. VII. Induction of uroporphyrinogen-I synthase and expression of the gene defect of acute intermittent porphyria in mitogen-stimulated human lymphocytes. J Clin Invest 1978 1.05
42 Hemin control of heme biosynthesis in mouse Friend virus-transformed erythroleukemia cells in culture. J Biol Chem 1978 1.04
43 Enzymatic studies on erythroid differentiation and proliferation. Ann N Y Acad Sci 1968 1.04
44 The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin. Proc Natl Acad Sci U S A 1985 1.03
45 Steroid induction of delta-aminolevulinic acid synthase and porphyrins in liver. Structure-activity studies and the permissive effects of hormones on the induction process. J Biol Chem 1979 1.01
46 Studies in porphyria. VIII. Relationship of the 5 alpha-reductive metabolism of steroid hormones to clinical expression of the genetic defect in acute intermittent porphyria. Am J Med 1979 1.01
47 Effects of a Chinese herbal medicine, keishi-bukuryo-gan, on the gonadal system of rats. J Ethnopharmacol 1989 1.00
48 Porphyrogenic effects and induction of heme oxygenase in vivo by delta-aminolevulinic acid. Biochim Biophys Acta 1981 1.00
49 Studies on the inheritance of human erythrocyte delta-aminolevulinate dehydratase and uroporphyrinogen synthetase. Enzyme 1973 1.00
50 Heme binding to murine erythroleukemia cells. Evidence for a heme receptor. J Biol Chem 1985 0.99
51 Hepatoerythropoietic porphyria: clinical, biochemical, and enzymatic studies in a three-generation family lineage. N Engl J Med 1987 0.98
52 The occurrence of molecular interactions among NADPH-cytochrome c reductase, heme oxygenase, and biliverdin reductase in heme degradation. J Biol Chem 1982 0.98
53 Plumbism from airborne lead in a firing range. An unusual exposure to a toxic heavy metal. Am J Med 1977 0.97
54 Regulation of 5-aminolevulinate synthase in mouse erythroleukemic cells is different from that in liver. J Biol Chem 1988 0.97
55 A novel mutation of the erythroid-specific delta-aminolaevulinate synthase gene in a patient with X-linked sideroblastic anaemia. Br J Haematol 1999 0.97
56 delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals. Biochem J 1989 0.96
57 A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspects of heme degradation by NADPH-cytochrome c reductase. J Biol Chem 1982 0.95
58 Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells. Biochem Biophys Res Commun 1989 0.95
59 Expression of cytochrome P450 mRNAs in the colon and the rectum in normal human subjects. Biochem Biophys Res Commun 1995 0.95
60 Heme oxygenase-1: a fundamental guardian against oxidative tissue injuries in acute inflammation. Mini Rev Med Chem 2007 0.95
61 Regulation of erythropoiesis in the Friend leukemia mouse. Blood 1968 0.95
62 Highly heterogeneous nature of delta-aminolevulinate dehydratase (ALAD) deficiencies in ALAD porphyria. Blood 2001 0.95
63 Inducible nitric oxide synthase: identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin. Proc Natl Acad Sci U S A 1995 0.94
64 delta-Aminolevulinate dehydratase in human erythroleukemia cells: an immunologically distinct enzyme. Blood 1985 0.94
65 The molecular defect of ferrochelatase in a patient with erythropoietic protoporphyria. Proc Natl Acad Sci U S A 1992 0.94
66 Interaction between succinyl CoA synthetase and the heme-biosynthetic enzyme ALAS-E is disrupted in sideroblastic anemia. J Clin Invest 2000 0.94
67 Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells. J Biol Chem 1982 0.92
68 Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme. J Biol Chem 1992 0.92
69 Fluorometric measurement of tin-protoporphyrin in biological samples. Anal Biochem 1984 0.91
70 Deficient heme and globin synthesis in embryonic stem cells lacking the erythroid-specific delta-aminolevulinate synthase gene. Blood 1998 0.91
71 Different responses of the hepatic and erythropoietic delta-aminolevulinic acid synthetase of mice. Biochim Biophys Acta 1967 0.91
72 Erythrocyte uroporphyrinogen decarboxylase activity in porphyria cutanea tarda: a study of 40 consecutive patients. J Invest Dermatol 1989 0.91
73 The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells. Biochem J 1993 0.91
74 Levels of delta-aminolevulinate dehydratase, uroporphyrinogen-I synthase, and protoporphyrin IX in erythrocytes from anemic mutant mice. Proc Natl Acad Sci U S A 1977 0.91
75 Purification and properties of human erythrocyte uroporphyrinogen decarboxylase: immunological demonstration of the enzyme defect in porphyria cutanea tarda. Trans Assoc Am Physicians 1983 0.91
76 Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event. Biochem J 1986 0.90
77 Lead intoxication: effects on cytochrome P-450-mediated hepatic oxidations. Clin Pharmacol Ther 1976 0.90
78 Adrenalectomy enhances the induction of heme oxygenase and the degradation of cytochrome P-450 in liver. J Biol Chem 1980 0.90
79 Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells. Biochem Biophys Res Commun 1992 0.90
80 Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells. Blood 1992 0.89
81 Studies in porphyria: functional evidence for a partial deficiency of ferrochelatase activity in mitogen-stimulated lymphocytes from patients with erythropoietic protoporphyria. J Clin Invest 1982 0.89
82 Effects of colloidal iron overload on renal and hepatic siderosis and the femur in male rats. Toxicology 2008 0.89
83 Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells. Biochem Biophys Res Commun 1990 0.89
84 Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes. Proc Natl Acad Sci U S A 1996 0.89
85 Marked developmental changes in heme oxygenase-1 (HO-1) expression in the mouse placenta: correlation between HO-1 expression and placental development. Placenta 2004 0.88
86 Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglion. I. Observations on neuronal and non-neuronal elements. J Neuropathol Exp Neurol 1978 0.88
87 Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes. Mol Pharmacol 1971 0.88
88 Effect of UVA and blue light on porphyrin biosynthesis in epidermal cells. Photochem Photobiol 1993 0.88
89 Cimetidine in the treatment of porphyria cutanea tarda. Intern Med 1996 0.87
90 Some biochemical and clinical aspects of lead intoxication. Adv Clin Chem 1978 0.87
91 Stimulators and inhibitors of hepatic porphyrin formation in human sera. J Clin Invest 1974 0.87
92 The influence of steroid hormone metabolites on the in vitro development of erythroid colonies derived from human bone marrow. J Exp Med 1979 0.87
93 Cloning and expression of the defective genes from a patient with delta-aminolevulinate dehydratase porphyria. J Clin Invest 1992 0.87
94 Five new mutations in the uroporphyrinogen decarboxylase gene identified in families with cutaneous porphyria. Blood 1996 0.86
95 Lead poisoning from art restoration and pottery work: unusual exposure source and household risk. J Environ Pathol Toxicol Oncol 1992 0.86
96 Photosensitivity, abnormal porphyrin profile, and sideroblastic anemia. J Am Acad Dermatol 1992 0.86
97 Sequential induction of enzymes in the heme biosynthetic pathway during erythroid differentiation. Nihon Ketsueki Gakkai Zasshi 1975 0.86
98 Studies in porphyria. V. Drug oxidation rates in hereditary hepatic porphyria. Clin Pharmacol Ther 1976 0.86
99 Effects of a new clerodane diterpenoid isolated from propolis on chemically induced skin tumors in mice. Anticancer Res 1996 0.86
100 The role of the erythroid-specific delta-aminolevulinate synthase gene expression in erythroid heme synthesis. Blood 1995 0.86
101 Analysis of porphyrin carboxylic acids in biological fluids by high-performance liquid chromatography. Anal Biochem 1982 0.86
102 The oxidative degradation of heme c by the microsomal heme oxygenase system. J Biol Chem 1982 0.86
103 5-Aminolevulinic acid dehydratase deficiency porphyria: a twenty-year clinical and biochemical follow-up. Clin Chem 1998 0.86
104 Sequential activation of genes for heme pathway enzymes during erythroid differentiation of mouse Friend virus-transformed erythroleukemia cells. Biochim Biophys Acta 1991 0.85
105 Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglia. II. The effect of lead. Environ Res 1979 0.85
106 Accumulation of protoporphyrin IX from delta-aminolevulinic acid in bovine skin fibroblasts with hereditary erythropoietic protoporphyria. A gene-dosage effect. J Exp Med 1981 0.85
107 Long-term administration of massive doses of Sn-protoporphyrin in anemic mutant mice (sphha/sphha). J Exp Med 1985 0.85
108 Studies in porphyria IX: Detection of the gene defect of erythropoietic protoporphyria in mitogen-stimulated human lymphocytes. Trans Assoc Am Physicians 1979 0.85
109 Novel molecular defects of the delta-aminolevulinate dehydratase gene in a patient with inherited acute hepatic porphyria. Hepatology 2000 0.84
110 Regulation of heme synthesis in HepG2 human hepatoma cells by dimethyl sulfoxide. Biochem Biophys Res Commun 1988 0.84
111 Proof that Sn-protoporphyrin inhibits the enzymatic catabolism of heme in vivo. Suppression of 14CO generation from radiolabeled endogenous and exogenous heme sources. J Exp Med 1987 0.84
112 A novel mutation of the erythroid-specific gamma-Aminolevulinate synthase gene in a patient with non-inherited pyridoxine-responsive sideroblastic anemia. Am J Hematol 1999 0.84
113 Effects of dimethyl sulphoxide on the synthesis of plasma proteins in the human hepatoma HepG2. Induction of an acute-phase-like reaction. Biochem J 1988 0.83
114 Endocrine-gene interaction in the pathogenesis of acute intermittent porphyria. Res Publ Assoc Res Nerv Ment Dis 1974 0.83
115 Regulation of beta-globin mRNA accumulation by heme in dimethyl sulfoxide (DMSO)-sensitive and DMSO-resistant murine erythroleukemia cells. Blood 1994 0.83
116 Growth-promoting effects of iron- and cobalt- protoporphyrins on cultured embryonic cells. J Cell Physiol 1983 0.83
117 Effects of danazol on DNA synthesis in rat prostate. Prostate 1993 0.83
118 Chronic effect of hyperprolactinemia on blood glucose and lipid levels in mice. Life Sci 1996 0.83
119 R411C mutation of the ALAS2 gene encodes a pyridoxine-responsive enzyme with low activity. Br J Haematol 1998 0.82
120 The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals. Pharmacology 1981 0.82
121 Increased erythrocyte uroporphyrinogen-l-synthetase, delta-aminolevulinic acid dehydratase and protoporphyrin in hemolytic anemias. Am J Med 1977 0.82
122 Uroporphyrinogen I synthase induction in normal human bone marrow cultures: an early and quantitative response of erythroid differentiation. Proc Natl Acad Sci U S A 1979 0.82
123 Metabolism of estradiol in liver cell culture. Differential responses of C-2 and C-16 oxidations to drugs and other chemicals that induce selective species of cytochrome P-450. J Clin Invest 1983 0.82
124 The rapid and decremental change in haem oxygenase mRNA during erythroid differentiation of murine erythroleukaemia cells. Br J Haematol 1989 0.81
125 Differential responses to inducers of delta-aminolaevulinate synthase and haem oxygenase during pregnancy. Biochem J 1981 0.81
126 Preventive effects of a herbal medicine on bone loss in rats treated with a GnRH agonist. Eur J Endocrinol 2000 0.81
127 Effects of metalloporphyrins on hemoglobin formation in mouse Friend virus-transformed erythroleukemia cells. Stimulation of heme biosynthesis by cobalt protoporphyrin. J Biol Chem 1982 0.81
128 Inhibition of the growth and differentiation of erythroid precursor cells by an endotoxin-induced mediator from peritoneal macrophages. Proc Natl Acad Sci U S A 1983 0.81
129 A novel mutation of delta-aminolaevulinate dehydratase in a healthy child with 12% erythrocyte enzyme activity. Br J Haematol 1999 0.81
130 The effect of ALA and radiation on porphyrin/heme biosynthesis in endothelial cells. Photochem Photobiol 1995 0.81
131 Splenomegaly induced by recombinant human granulocyte-colony stimulating factor in rats. Life Sci 2001 0.81
132 Four species of cDNAs for cytochrome P450 isozymes immunorelated to P450C-M/F encode for members of P450IID subfamily, increasing the number of members within the subfamily. Biochem Biophys Res Commun 1988 0.81
133 Enzymatic defect in a child with hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: immunochemical studies. Pediatrics 1987 0.80
134 Message amplification phenotyping of an inherited delta-aminolevulinate dehydratase deficiency in a family with acute hepatic porphyria. Biochem Biophys Res Commun 1990 0.80
135 Lead intoxication among demolition workers: the effect of lead on the hepatic cytochrome P-450 system in humans. J Toxicol Environ Health 1977 0.80
136 The third case of Doss porphyria (delta-amino-levulinic acid dehydratase deficiency) in Germany. J Inherit Metab Dis 2004 0.80
137 Succinylacetone inhibits delta-aminolevulinate dehydratase and potentiates the drug and steroid induction of delta-aminolevulinate synthase in liver. Trans Assoc Am Physicians 1982 0.80
138 The effect of erythropoietin on hematopoietic organs of the polycythemic mouse. Blood 1966 0.80
139 Porphyrin-heme biosynthesis in organotypic cultures of mouse dorsal root ganglia. Effects of heme and lead on porphyrin synthesis and peripheral myelin. J Clin Invest 1984 0.80
140 Hereditary tyrosinemia. Formation of succinylacetone-amino acid adducts. J Exp Med 1985 0.80
141 Assignment of the gene for uroporphyrinogen decarboxylase to human chromosome 1 by somatic cell hybridization and specific enzyme immunoassay. Hum Genet 1984 0.80
142 Molecular basis of variegate porphyria: a de novo insertion mutation in the protoporphyrinogen oxidase gene. Hum Genet 1997 0.80
143 Molecular analysis of delta-aminolevulinate dehydratase deficiency in a patient with an unusual late-onset porphyria. Blood 2000 0.79
144 Immunochemical study of uroporphyrinogen decarboxylase in a patient with mild hepatoerythropoietic porphyria. J Clin Invest 1987 0.79
145 ADP-ribosyltransferase activity during the friend virus-induced murine erythroleukemia cell differentiation. J Biol Chem 1983 0.79
146 An immunological study of delta-aminolevulinic acid dehydratase specificity consistent with the phylogeny of species. Biochim Biophys Acta 1984 0.79
147 A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene. Biochem J 1991 0.79
148 DNA fragments in Friend erythroleukemia cells induced by dimethyl sulfoxide. Proc Natl Acad Sci U S A 1983 0.78
149 Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation. Biochem Biophys Res Commun 1987 0.78
150 Induction of delta-aminolevulinic acid dehydratase in mouse Friend virus-transformed erythroleukemia cells during erythroid differentiation. Blood 1984 0.78
151 The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells. Biochem J 1989 0.78
152 Preventive effects of sulphasalazine on colorectal carcinogenesis in mice with ulcerative colitis. In Vivo 2000 0.78
153 Characterization and expression of cDNA encoding coproporphyrinogen oxidase from a patient with hereditary coproporphyria. Hum Mol Genet 1994 0.77
154 Haem is necessary for a continued increase in ferrochelatase mRNA in murine erythroleukaemia cells during erythroid differentiation. Br J Haematol 1993 0.77
155 Growth hormone stimulates drug-induced porphyrin formation in liver cells maintained in a serum-free medium. J Biol Chem 1981 0.77
156 Additional effects of medroxyprogesterone acetate on mammary tumors in oophorectomized, estrogenized, DMBA-treated rats. Anticancer Res 1998 0.77
157 Dexamethasone and erythroid colony formation: contrasting effects in mouse and human bone marrow cells in culture. Br J Haematol 1979 0.77
158 Conservative management for perimenopausal women with uterine leiomyomas using Chinese herbal medicines and synthetic analogs of gonadotropin-releasing hormone. In Vivo 1998 0.77
159 Effects of luteinizing hormone-releasing hormone analogue on DNA synthesis in rat prostate and uterus. In Vivo 1993 0.77
160 Suppression of the development of uterine adenomyosis by danazol treatment in mice. Life Sci 1992 0.77
161 Effect of interleukin-11 on the levels of mRNAs encoding heme oxygenase and haptoglobin in human HepG2 hepatoma cells. Biochem Biophys Res Commun 1993 0.77
162 Three new mutations in the uroporphyrinogen decarboxylase gene in familial porphyria cutanea tarda. Mutation in brief no. 237. Online. Hum Mutat 1999 0.77
163 Analysis of porphyrins and enzymes in porphyrin synthesis in Taenia solium cysticercus from man and pig. Mol Biochem Parasitol 1987 0.76
164 Tin-protoporphyrin inhibits heme oxygenase and prevents the decline in hepatic heme and cytochrome P-450 contents produced in nude mice by tumor transplantation. Biochem Biophys Res Commun 1988 0.76
165 Phenotypic variation in human HepG2 hepatoma cells: alterations in cell growth, plasma protein synthesis and heme pathway enzymes. Int J Biochem 1990 0.76
166 Prevention of osteopenia induced with a gonadotropin-releasing hormone agonist in rats. Calcif Tissue Int 1999 0.76
167 Heme synthesis in Friend ascites tumor cells. Proc Soc Exp Biol Med 1968 0.76
168 Chloro-substituent sites and probability of co-planarity in polychlorinated biphenyls in determining uroporphyrin formation in cultured liver cells. Biochem J 1986 0.75
169 Phenobarbital does not increase early labeling of bilirubin from 4-[14C]-delta-aminolevulinic acid in man and rat. Hepatology 1991 0.75
170 5-Aminolevulinate synthase expression and hemoglobin synthesis in a human myelogenous leukemia cell line. J Biochem 1997 0.75
171 Immunochemical detection of cytochrome P450C-M/F and NADPH-cytochrome P450 reductase in rat liver and kidney. Biochem Biophys Res Commun 1988 0.75
172 Stimulation of hepatic porphyrin synthesis in tissue culture by sera of patients with acute porphyria. Trans Assoc Am Physicians 1969 0.75
173 Semimicroassay method for hepatic delta-aminolevulinic acid synthetase activity. J Lab Clin Med 1970 0.75
174 Effect of soluble complement receptor type 1 on porphyrin-induced phototoxicity in guinea pigs. J Photochem Photobiol B 1998 0.75
175 Porphyrin synthesis by murine epidermal cells. Skin Pharmacol 1993 0.75
176 Pharmacotherapeutic effects of toki-shakuyaku-san on leukorrhagia in young women. Am J Chin Med 1996 0.75
177 [Significance of delta-aminolevulinic acid synthase analysis in clinical tests]. Nihon Rinsho 1989 0.75
178 Uterine estrogen receptor assayed by the controlled pore glass (CPG) method in adult rat after steroid administration. Bull Tokyo Med Dent Univ 1981 0.75
179 Absence of close linkage between acute intermittent porphyria and the ABO, Rh, P, acid phosphatase, Pr, orosmucoid and pepsinogen loci. Hum Hered 1982 0.75
180 Lead poisoning in an art conservator. JAMA 1982 0.75
181 [Effects of ACTH or hCG on corticosterone and progesterone secretion from adrenal glands of the rats at various ages]. Nihon Naibunpi Gakkai Zasshi 1987 0.75
182 Myocardial energy metabolism and protection of heart muscle at low temperatures. Recent Adv Stud Cardiac Struct Metab 1978 0.75
183 [Polycythemia]. Naika 1967 0.75
184 An acquired acute hepatic porphyria: a novel type of delta-aminolevulinate dehydratase inhibition. Clin Chim Acta 1992 0.75
185 [The behavior of 7, 12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in rats during pregnancy and lactation and hormone levels in the pituitary and plasma (author's transl)]. Nihon Naibunpi Gakkai Zasshi 1979 0.75
186 Differential induction responses of delta-aminolevulinate synthase mRNAs during erythroid differentiation: use of nonradioactive in situ hybridization. Am J Hematol 1992 0.75
187 A comparison of the utility of Dowex resin and polybenzimidazole Aurorez resin in the determination of urinary porphobilinogen concentrations. Clin Chim Acta 1987 0.75
188 [Preparation of progesterone secreting cells from rat ovaries by a density gradient]. Nihon Naibunpi Gakkai Zasshi 1983 0.75
189 Changes with age of mammary glands in male and female soft-furred rat, Millardia meltada, in relation to prolactin and testosterone. Lab Anim 1994 0.75
190 The effect of porphyrin and radiation on ferrochelatase and 5-aminolevulinic acid synthase in epidermal cells. Photodermatol Photoimmunol Photomed 1995 0.75
191 Development of porphyria cutanea tarda after treatment with cyclophosphamide. Gastroenterology 1988 0.75
192 Aromatization and 19-hydroxylation of androgens by rat brain cytochrome P-450. Biochem Biophys Res Commun 1988 0.75
193 Survival of two patients with severe delta-aminolaevulinic acid dehydratase deficiency porphyria. J Inherit Metab Dis 2001 0.75
194 1-(2-Tetrahydrofuryl)-5-fluorouracil in combination with uracil suppresses mammary carcinogenesis and growth of tumors induced with 7,12-dimethylbenz[a]anthracene in rats. Anticancer Drugs 1996 0.75
195 Childhood-onset familial porphyria cutanea tarda: effects of therapeutic phlebotomy. J Am Acad Dermatol 1992 0.75
196 Studies of erythrocyte protoporphyrin in anemic mutant mice: use of a modified hematofluorometer for the detection of heterozygotes for hemolytic disease. Exp Hematol 1978 0.75
197 Effects of 5-fluorouracil derivative UFT on thymidylate synthetase and thymidine kinase in rat colorectal tumors. Anticancer Res 1999 0.75
198 Cytochrome P-450C-M/F, a new constitutive form of microsomal cytochrome P-450 in male and female rat liver with estrogen 2- and 16 alpha-hydroxylase activity. Biochemistry 1988 0.75
199 Extremely rare association of HFE mutations with porphyria cutanea tarda in Japanese patients. Hepatology 1999 0.75
200 Heme synthesis in normal and leukemic leukocytes. Cancer Res 1968 0.75
201 Lead hazard among ironworkers. Dismantling lead-painted elevated subway line in New York City. N Y State J Med 1978 0.75
202 [The extraction of biologically active substances from hop]. Nihon Naibunpi Gakkai Zasshi 1984 0.75
203 Effects of tamoxifen on mammary tumors and bone in 7,12-dimethylbenz-(a)anthracene-treated rats. Anticancer Res 1998 0.75
204 [Autoimmune hemolytic anemia terminating in the aplasia of bone marrow associated with agranulocytosis and leukemoid reaction]. Nihon Ketsueki Gakkai Zasshi 1967 0.75
205 Acute intermittent porphyria. Ann Intern Med 1981 0.75
206 Polychlorinated aromatic hydrocarbon lethality, mixed-function oxidase induction, and uroporphyrinogen decarboxylase inhibition in the chick embryo: dissociation of dose-response relationships. Toxicol Appl Pharmacol 1985 0.75
207 Lack of effect of pregnancy or hematin therapy on erythrocyte porphobilinogen deaminase activity in acute intermittent porphyria. N Engl J Med 1989 0.75
208 Absence of C282Y and H63D mutations of the hemochromatosis gene in Japanese patients with sideroblastic anemia. Am J Hematol 1999 0.75
209 Early-stage HIV infection and hepatitis C virus infection are associated with elevated serum porphyrin levels. J Am Acad Dermatol 1998 0.75
210 Effects of danazol on endometrial DNA synthesis in rats. Steroids 1993 0.75
211 [Clinical study on clamping of persistent left superior vena cava (PLSVC) during extracorporeal circulation in cases of congenital heart disease (CHD) associated with PLSVC (author's transl)]. Kyobu Geka 1979 0.75
212 Effects of conjugated estrogens with or without medroxyprogesterone acetate on mammary carcinogenesis, uterine adenomyosis and femur in mice. Acta Anat (Basel) 1997 0.75
213 Effects of danazol on proliferation and viability of 7,12-dimethylbenz(a)anthracene-induced mammary tumours in rats. Anticancer Res 1995 0.75
214 [Significance of delta-aminolevulinic acid dehydratase analysis in clinical tests]. Nihon Rinsho 1989 0.75
215 [The busulfan therapy of chronic granulocytic leukemia]. Nihon Naika Gakkai Zasshi 1969 0.75
216 Effects of long-term administration of UFT plus leucovorin on colorectal tumors induced with 1,2-dimethylhydrazine in rats. Anticancer Res 2000 0.75
217 Prenatal diagnosis of acute intermittent porphyria. N Engl J Med 1976 0.75
218 The effects of early treatment of hereditary tyrosinemia type I in infancy by orthotopic liver transplantation. Transplantation 1990 0.75
219 Dimethyl sulphoxide and haemin induce ferrochelatase mRNA by different mechanisms in murine erythroleukaemia cells. Br J Haematol 1993 0.75
220 [Significance of delta-aminolevulinic acid analysis in clinical tests]. Nihon Rinsho 1989 0.75
221 Novel regulation of delta-aminolevulinate synthase in the rat harderian gland. Biochem Pharmacol 1997 0.75
222 Abnormal serum porphyrin levels in patients with the acquired immunodeficiency syndrome with or without hepatitis C virus infection. Arch Dermatol 1996 0.75
223 Hormonal regulation of heme oxygenase induction in avian hepatocyte culture. Biochem Pharmacol 1985 0.75
224 [Heme synthesis and its abnormality]. Rinsho Ketsueki 1997 0.75
225 [A study of factors contributing to myocardial protection during open heart surgery (author's transl)]. Kyobu Geka 1978 0.75
226 Increased lead absorption in a potter and her family members. N Y State J Med 1991 0.75
227 Preventive effects of polysaccharides extracted from human tubercle bacilli (specific substance of Maruyama) on colonic carcinogenesis in rats. Cancer Detect Prev 1997 0.75
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