Published in Lancet on September 13, 1986
Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J (1993) 3.75
Two episodes of life-threatening anaphylaxis in the same patient to a chlorhexidine-sulphadiazine-coated central venous catheter. Br J Anaesth (2001) 2.49
Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones. Immunity (1996) 2.27
Cannabis for dyskinesia in Parkinson disease: a randomized double-blind crossover study. Neurology (2004) 1.73
A positron emission tomography study of essential tremor: evidence for overactivity of cerebellar connections. Ann Neurol (1993) 1.58
Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain? J Clin Invest (1997) 1.43
Disorders of ocular motility. Br J Hosp Med (1990) 1.40
Periodicity of DNA folding in higher order chromatin structures. EMBO J (1990) 1.39
TWEAK stimulation of astrocytes and the proinflammatory consequences. Glia (2000) 1.38
The role of the subthalamic nucleus in response inhibition: evidence from deep brain stimulation for Parkinson's disease. Neuropsychologia (2009) 1.38
Electron microscopy of tissue adherent to explanted electrodes in dystonia and Parkinson's disease. Brain (2004) 1.36
Primary monolayer cultures of adult rat liver parenchymal cells suitable for study of the regulation of enzyme synthesis. In Vitro (1977) 1.27
Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes. J Cell Sci (1996) 1.26
A study of tremor in multiple sclerosis. Brain (2001) 1.26
The roles of calcium and cyclic AMP in cell proliferation. Ann N Y Acad Sci (1980) 1.17
Survey of clinical allergy services provided by clinical immunologists in the UK. J Clin Pathol (2005) 1.17
Glycolytic isoenzymes and glycogen metabolism in regenerating liver from rats on controlled feeding schedules. Biochem J (1973) 1.16
A quantitative, single-cell PCR analysis of an antigen-specific TCR repertoire selected during an in vivo CD8 response: direct evidence for a wide range of clone sizes with uniform tissue distribution. Mol Immunol (1999) 1.12
Tremor in multiple sclerosis. J Neurol Neurosurg Psychiatry (1999) 1.10
Abrupt withdrawal of atenolol in patients with severe angina. Comparison with the effects of treatment. Br Heart J (1985) 1.10
Patient tolerance to intravenous potassium chloride with and without lidocaine. Drug Intell Clin Pharm (1988) 1.08
Stereotactic lesional surgery for the treatment of tremor in multiple sclerosis: a prospective case-controlled study. Brain (2001) 1.07
Deep brain stimulation: a new treatment for hypertension? J Clin Neurosci (2007) 1.06
A comparison of fast Fourier transform (FFT) and autoregressive (AR) spectral estimation techniques for the analysis of tremor data. J Neurosci Methods (1998) 1.06
Isolation and function of human dendritic cells. Int Rev Cytol (1994) 1.05
CD95 (Fas/Apo-1) as a receptor governing astrocyte apoptotic or inflammatory responses: a key role in brain inflammation? J Immunol (1999) 1.04
Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. Biochem Cell Biol (1994) 1.00
The topoisomerase II inhibitor teniposide (VM-26) induces apoptosis in unstimulated mature murine lymphocytes. Exp Cell Res (1992) 0.99
Incidence, character and clinical relevance of mixed cryoglobulinaemia in patients with chronic hepatitis C virus infection. Clin Exp Immunol (1996) 0.99
The regulatory and catalytic subunits of cAMP-dependent protein kinases are associated with transcriptionally active chromatin during changes in gene expression. J Biol Chem (1988) 0.99
The effect of cannabis on tremor in patients with multiple sclerosis. Neurology (2004) 0.99
Fundamental differences between the standard 12-lead electrocardiograph and the modified (Mason-Likar) exercise lead system. Eur Heart J (1987) 0.98
Apoptosis-related functional features of the DNaseI-like family of nucleases. Ann N Y Acad Sci (1999) 0.98
Food and light as separate entrainment signals for rat liver enzymes. Adv Enzyme Regul (1973) 0.98
Evaluation of three different ways of assessing tremor in multiple sclerosis. J Neurol Neurosurg Psychiatry (2000) 0.97
Antibody responses to vaccinations given within the first two years after transplant are similar between autologous peripheral blood stem cell and bone marrow transplant recipients. Bone Marrow Transplant (2001) 0.97
Oxidative stress regulated expression of ubiquitin Carboxyl-terminal Hydrolase-L1: role in cell survival. Apoptosis (2006) 0.95
Bickerstaff's brainstem encephalitis, Miller Fisher syndrome and Guillain-Barre syndrome overlap with negative anti-GQ1b antibodies. Eur J Neurol (2003) 0.95
High-titre circulating tissue transglutaminase-2 antibodies predict small bowel villous atrophy, but decision cut-off limits must be locally validated. Clin Exp Immunol (2014) 0.95
Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation. Eur J Neurol (2003) 0.94
Intercellular adhesion molecule-3 is the predominant co-stimulatory ligand for leukocyte function antigen-1 on human blood dendritic cells. Eur J Immunol (1995) 0.94
Inhibition by colchicine of changes in amino acid transport and initiation of DNA synthesis in regenerating rat liver. Proc Natl Acad Sci U S A (1978) 0.94
Treatment of suspected postcholecystectomy diarrhea with psyllium hydrophilic mucilloid. Clin Pharm (1990) 0.94
An unusual case of shock in a young woman. Postgrad Med J (1989) 0.94
Abnormal responses of rheumatoid arthritis lymphocytes to Epstein-Barr virus infection in vitro: evidence for multiple defects. Ann Rheum Dis (1985) 0.93
Isoenzyme patterns in parenchymal and non-parenchymal cells isolated from regenerating and regenerated rat liver. Biochem J (1973) 0.93
Raised tryptase without anaphylaxis or mastocytosis: heterophilic antibody interference in the serum tryptase assay. Clin Exp Immunol (2011) 0.92
Regulation of proliferation of normal and neoplastic rat liver cells by calcium and cyclic AMP. Ann N Y Acad Sci (1980) 0.91
Isozyme studies on adult, regenerating, precancerous and developing liver in relation to findings in hepatomas. Adv Enzyme Regul (1972) 0.90
Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires. Cancer Res (2001) 0.90
TCR analysis reveals significant repertoire selection during in vitro lymphocyte culture. Int Immunol (1997) 0.90
The inhibition by colchicine of the initiation of DNA synthesis by hepatocytes in regenerating rat liver and by cultivated WI-38 and C3H10T1/2 cells. J Cell Physiol (1977) 0.90
Cytoplasmic microtubules are essential for the formation of membrane-bound polyribosomes. J Biol Chem (1985) 0.89
Identification of a multiprotein complex interacting with the c-fos serum response element. Mol Cell Biol (1991) 0.89
Juvenile dermatomyositis associated with hereditary angioneurotic oedema. Arch Dis Child (2002) 0.89
Regulation of DNaseY activity by actinin-alpha4 during apoptosis. Cell Death Differ (2004) 0.88
DNaseY: a rat DNaseI-like gene coding for a constitutively expressed chromatin-bound endonuclease. Biochemistry (1998) 0.87
A comparison of the properties of the phosphofructokinases of the fat body and flight muscle of the adult male desert locust. Biochem J (1969) 0.87
Astrocytoma infiltrating lymphocytes include major T cell clonal expansions confined to the CD8 subset. Int Immunol (1999) 0.86
Mapping the initial DNA breaks in apoptotic Jurkat cells using ligation-mediated PCR. Cell Death Differ (2003) 0.86
Modulation of the sensitivity of chromatin to exogenous nucleases: implications for the apparent increased sensitivity of transcriptionally active genes. Biochemistry (1986) 0.85
Paraplegia after iopamidol myelography. Lancet (1991) 0.85
Identification of a novel 97 kDa endonuclease capable of internucleosomal DNA cleavage. Biochemistry (1997) 0.85
Pacing failure due to flecainide acetate. Pacing Clin Electrophysiol (1985) 0.85
Individual differences in expert motor coordination associated with white matter microstructure in the cerebellum. Cereb Cortex (2012) 0.85
Efficacy of transdermal glyceryl trinitrate in the treatment of chronic stable angina pectoris. Br Heart J (1985) 0.85
Chromatin structure. Nuclease digestion profiles reflect intermediate stages in the folding of the 30-nm fiber rather than the existence of subunit beads. J Biol Chem (1986) 0.84
Separate pools of endonuclease activity are responsible for internucleosomal and high molecular mass DNA fragmentation during apoptosis. Biochem Cell Biol (1995) 0.84
A comparison of the properties of the pyruvate kinases of the fat body and flight muscle of the adult male desert locust. Biochem J (1969) 0.84
Defective rheumatoid lymphocyte function assessed by Epstein-Barr virus infection in vitro. Lancet (1982) 0.82
Jun and JNK kinase are activated in thymocytes in response to VM26 and radiation but not glucocorticoids. Exp Cell Res (1997) 0.82
Quality not quantity for transglutaminase antibody 2: the performance of an endomysial and tissue transglutaminase test in screening coeliac disease remains stable over time. Clin Exp Immunol (2013) 0.82
Target board test for the quantification of ataxia in tremulous patients. Clin Rehabil (2003) 0.82
Pyruvate kinase, hexokinase, and aldolase isozymes in rat liver cells in culture. In Vitro (1973) 0.82
Modification of radiation-induced apoptosis in radiation- or hyperthermia-adapted human lymphocytes. Biochem Cell Biol (1995) 0.81
Allosteric properties of a pyruvate kinase isoenzyme from rat liver cells in culture. J Biol Chem (1973) 0.81
The protein kinases of rat liver nuclei. Biochem Biophys Res Commun (1980) 0.81
Two-stage cell shrinkage and the OER for radiation-induced apoptosis of rat thymocytes. Int J Radiat Biol (1993) 0.81
Role of "malic enzyme" in lipogenesis. Biochim Biophys Acta (1969) 0.81
The regulation of enzyme synthesis in animal cells. Essays Biochem (1977) 0.80
Evidence that mammalian ribonucleotide reductase is a nuclear membrane associated glycoprotein. Biochem Cell Biol (1990) 0.80
Advising patients on dealing with acute chest pain. BMJ (2007) 0.80
Effects of hormones and serum on glycogen metabolism in adult rat liver parenchymal cell primary cultures. J Cell Physiol (1977) 0.79
High precision isotope measurements reveal poor control of copper metabolism in parkinsonism. Metallomics (2013) 0.79
Hodgkin's disease cell lines: a model for interleukin-1-independent accessory cell function. Immunology (1992) 0.79
Serological testing for coeliac disease in Type 1 diabetes mellitus: is immunoglobulin A level measurement necessary? Diabet Med (2013) 0.79
Deep brain stimulation in Parkinson's disease. J Neurol Neurosurg Psychiatry (1999) 0.79
Infection in the renal transplant patient. J R Soc Med (1978) 0.79
Dipyridamole combined with exercise for thallium-201 myocardial imaging. Br Heart J (1986) 0.79
Chromatin structure. Evidence that the 30-nm fiber is a helical coil with 12 nucleosomes/turn. J Biol Chem (1987) 0.79
Unique behaviour of NuMA during heat-induced apoptosis of lymphocytes. Biochem Cell Biol (1997) 0.79
Diurnal rhythms of hepatic carbohydrate metabolism during development of the rat. Biochem J (1974) 0.78
Evidence for trans regulation of apoptosis in intertypic somatic cell hybrids. Mol Cell Biol (1994) 0.78
Degradation of constitutive transcription factors during apoptosis in rat thymocytes. Biochem Cell Biol (1995) 0.78
Colchicine prevents the translation of mRNA molecules transcribed immediately after proliferative activation of hepatocytes in regenerating rat liver. J Cell Physiol (1984) 0.78
Changes in cyclic adenosine monophosphate-responsive element binding proteins in rat hepatomas. Cancer Res (1991) 0.78
Calcium, cyclic AMP and protein kinase C--partners in mitogenesis. Cancer Metastasis Rev (1987) 0.78
Identification of a new cAMP response element-binding factor by southwestern blotting. J Biol Chem (1993) 0.78
Permeability of latex and polyvinyl chloride gloves to fluorouracil and methotrexate. Am J Hosp Pharm (1987) 0.78