Published in J Leukoc Biol on July 28, 2017
Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 24.36
Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity (2003) 21.56
Caspases: enemies within. Science (1998) 19.45
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol (2000) 14.74
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med (2007) 11.51
Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science (2009) 10.47
Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science (2007) 9.54
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol (2004) 8.65
The Immunological Genome Project: networks of gene expression in immune cells. Nat Immunol (2008) 7.23
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity (2012) 6.18
Requirement for NF-kappaB in osteoclast and B-cell development. Genes Dev (1997) 5.65
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse. Proc Natl Acad Sci U S A (1990) 5.05
Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J Exp Med (2006) 4.91
Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J Exp Med (2001) 3.96
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development (1994) 3.86
Transcriptional control of granulocyte and monocyte development. Oncogene (2007) 3.49
The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes. Nat Immunol (2011) 3.19
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity (2012) 3.18
Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J Cell Sci (2010) 3.17
RAFTK/Pyk2-mediated cellular signalling. Cell Signal (2000) 2.76
The mononuclear phagocyte system. Curr Opin Immunol (2005) 2.65
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 2.61
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood (2008) 2.52
Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal. Cell (2013) 2.49
Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations. J Immunol (2009) 2.46
Lipopolysaccharide, tumor necrosis factor-alpha, and IL-1 beta prevent programmed cell death (apoptosis) in human peripheral blood monocytes. J Immunol (1991) 2.39
Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration. Proc Natl Acad Sci U S A (2003) 2.34
Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines. J Immunol (1991) 2.23
Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase. J Cell Biol (2007) 1.93
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol (2007) 1.92
Origin of monocytes and macrophages in a committed progenitor. Nat Immunol (2013) 1.84
Migration of leukocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes. J Leukoc Biol (1999) 1.67
Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1. J Immunol (1999) 1.57
Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages. J Exp Med (1997) 1.56
Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B. J Biol Chem (1999) 1.51
Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase. J Cell Biol (1997) 1.50
Toward a refined definition of monocyte subsets. Front Immunol (2013) 1.45
Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death. J Innate Immun (2010) 1.44
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis. Proc Natl Acad Sci U S A (2007) 1.38
Apoptosis in human monocytes: possible role in chronic inflammatory diseases. J Periodontol (1993) 1.26
Activation of p38 mitogen-activated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism. J Biol Chem (1999) 1.20
Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage. Cell Signal (2012) 1.19
Regulation of monocyte apoptosis by the protein kinase Cdelta-dependent phosphorylation of caspase-3. J Biol Chem (2005) 1.19
Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival. J Biol Chem (2009) 1.18
Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis. J Biol Chem (2007) 1.15
Homeostasis in the mononuclear phagocyte system. Trends Immunol (2014) 1.10
Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin. J Biol Chem (2004) 1.06
Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells. Leukemia (2007) 1.06
Macrophage-colony-stimulating factor-induced activation of extracellular-regulated kinase involves phosphatidylinositol 3-kinase and reactive oxygen species in human monocytes. J Immunol (2002) 1.05
Monocyte survival factors induce Akt activation and suppress caspase-3. Am J Respir Cell Mol Biol (2002) 1.00
Critical role of the FERM domain in Pyk2 stimulated glioma cell migration. Biochem Biophys Res Commun (2006) 0.98
Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection. J Immunol (2010) 0.94
PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells. Carcinogenesis (2006) 0.93
Mouse blood monocytes: standardizing their identification and analysis using CD115. J Immunol Methods (2011) 0.92
RAFTK/PYK2-dependent and -independent apoptosis in multiple myeloma cells. Oncogene (1999) 0.89
Focal adhesion kinase upregulated by granulocyte-macrophage colony-stimulating factor but not by interleukin-3 in differentiating myeloid cells. Blood (1997) 0.88
Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System. J Immunol (2015) 0.87
Role of PYK2 in the development of obesity and insulin resistance. Biochem Biophys Res Commun (2005) 0.86
Regulation of osteoclast structure and function by FAK family kinases. J Leukoc Biol (2012) 0.85
Control of dendritic cell migration, T cell-dependent immunity, and autoimmunity by protein tyrosine phosphatase PTPN12 expressed in dendritic cells. Mol Cell Biol (2013) 0.84
Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma. Oncogene (2015) 0.83
Induction of proline-rich tyrosine kinase2 (Pyk2) through C/EBPbeta is involved in PMA-induced monocyte differentiation. FEBS Lett (2008) 0.82
The Fas-FasL death receptor and PI3K pathways independently regulate monocyte homeostasis. Eur J Immunol (2001) 0.82
M-CSF Mediates Host Defense during Bacterial Pneumonia by Promoting the Survival of Lung and Liver Mononuclear Phagocytes. J Immunol (2016) 0.76