Published in BMC Cancer on August 02, 2017
Hallmarks of cancer: the next generation. Cell (2011) 140.01
Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell (2007) 22.89
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer (2009) 18.53
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res (2009) 7.98
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res (2006) 7.91
Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer (2013) 6.13
Slug and Sox9 cooperatively determine the mammary stem cell state. Cell (2012) 4.77
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery. PLoS One (2009) 4.62
Evolution of the cancer stem cell model. Cell Stem Cell (2014) 4.38
Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis (2004) 3.66
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression. J Biol Chem (2002) 3.18
Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer (2005) 2.89
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. J Cell Mol Med (2008) 2.67
Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene (2012) 1.95
Cell fusion: a hidden enemy? Cancer Cell (2003) 1.95
Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8. Cancer Res (2013) 1.80
Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming. Cancer Res (2011) 1.73
Triple negative breast cancer cell lines: one tool in the search for better treatment of triple negative breast cancer. Breast Dis (2010) 1.64
Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ. J Pathol (2002) 1.56
Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and response to SV40 transfection. Carcinogenesis (1995) 1.56
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature (2015) 1.53
Cell fusion as a hidden force in tumor progression. Cancer Res (2009) 1.51
Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants. Proc Natl Acad Sci U S A (2009) 1.45
Cell Fusion Connects Oncogenesis with Tumor Evolution. Am J Pathol (2015) 1.44
Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc Natl Acad Sci U S A (2014) 1.43
Basoluminal carcinoma: a new biologically and prognostically distinct entity between basal and luminal breast cancer. Clin Cancer Res (2006) 1.38
A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis. Radiat Res (2001) 1.27
Melanoma x macrophage hybrids with enhanced metastatic potential. Clin Exp Metastasis (1998) 1.23
Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium. Cancer Res (2006) 1.21
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis. Front Oncol (2015) 1.15
Spontaneous formation of tumorigenic hybrids between breast cancer and multipotent stromal cells is a source of tumor heterogeneity. Am J Pathol (2012) 1.14
A spontaneous murine melanoma lung metastasis comprised of host x tumor hybrids. Cancer Res (2000) 1.11
Recurrence cancer stem cells--made by cell fusion? Med Hypotheses (2009) 1.05
Towards elucidating the connection between epithelial-mesenchymal transitions and stemness. J R Soc Interface (2014) 1.04
High susceptibility of a human breast epithelial cell type with stem cell characteristics to telomerase activation and immortalization. Cancer Res (1999) 1.01
Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells. Clin Exp Metastasis (2010) 0.99
Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival. PLoS One (2015) 0.99
EMT and acquisition of stem cell-like properties are involved in spontaneous formation of tumorigenic hybrids between lung cancer and bone marrow-derived mesenchymal stem cells. PLoS One (2014) 0.96
Functional regulation of Slug/Snail2 is dependent on GSK-3β-mediated phosphorylation. FEBS J (2012) 0.92
Hybrid cells derived from breast epithelial cell/breast cancer cell fusion events show a differential RAF-AKT crosstalk. Cell Commun Signal (2012) 0.87
Fusion-derived epithelial cancer cells express hematopoietic markers and contribute to stem cell and migratory phenotype in ovarian carcinoma. Cancer Res (2013) 0.85
Tissue Regeneration in the Chronically Inflamed Tumor Environment: Implications for Cell Fusion Driven Tumor Progression and Therapy Resistant Tumor Hybrid Cells. Int J Mol Sci (2015) 0.85
Estrogen receptor, progesterone receptor, interleukin-6 and interleukin-8 are variable in breast cancer and benign stem/progenitor cell populations. BMC Cancer (2014) 0.83
Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer. Cell Rep (2015) 0.81
Cell fusion in health and disease. Volume II: cell fusion in disease. Introduction. Adv Exp Med Biol (2011) 0.79
Analysis of cell migration within a three-dimensional collagen matrix. J Vis Exp (2014) 0.78
Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness. BMC Cancer (2015) 0.78
Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer. Sci Rep (2017) 0.78
CD34(+) Liver Cancer Stem Cells Were Formed by Fusion of Hepatobiliary Stem/Progenitor Cells with Hematopoietic Precursor-Derived Myeloid Intermediates. Stem Cells Dev (2015) 0.77
Reduced tumorigenicity and drug resistance through the downregulation of octamer-binding protein 4 and Nanog transcriptional factor expression in human breast stem cells. Mol Med Rep (2014) 0.76
Fusion with stem cell makes the hepatocellular carcinoma cells similar to liver tumor-initiating cells. BMC Cancer (2016) 0.76
Chemotherapy promotes tumour cell hybridization in vivo. Tumour Biol (2015) 0.76