Published in BMC Nephrol on August 11, 2017
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet (1999) 25.93
Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (2010) 16.00
A tutorial on statistical methods for population association studies. Nat Rev Genet (2006) 12.49
Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene. Hum Genet (2010) 5.68
Apolipoprotein L-I is the trypanosome lytic factor of human serum. Nature (2003) 4.33
Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney Int (2012) 3.46
An integrated map of structural variation in 2,504 human genomes. Nature (2015) 3.30
Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science (2005) 3.06
Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1. Kidney Int (2014) 2.83
Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death. J Biol Chem (2008) 2.30
C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. PLoS Pathog (2009) 2.22
A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. Kidney Int (2010) 2.22
The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. Genomics (2002) 2.20
Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. J Lipid Res (2001) 2.02
Tag SNP selection in genotype data for maximizing SNP prediction accuracy. Bioinformatics (2005) 1.73
APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans. J Am Soc Nephrol (2015) 1.73
APOL1 variants and kidney disease in people of recent African ancestry. Nat Rev Nephrol (2013) 1.43
Mechanism of Trypanosoma brucei gambiense resistance to human serum. Nature (2013) 1.28
Performance of genotype imputations using data from the 1000 Genomes Project. Hum Hered (2011) 1.25
Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22. Proc Natl Acad Sci U S A (2002) 1.22
Gene-gene interactions in APOL1-associated nephropathy. Nephrol Dial Transplant (2013) 1.21
The SRA gene: the key to understanding the nature of Trypanosoma brucei rhodesiense. Parasitology (2005) 1.15
Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia. Transl Psychiatry (2013) 1.07
Power and sample size for testing associations of haplotypes with complex traits. Ann Hum Genet (2006) 1.07
APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults. Arterioscler Thromb Vasc Biol (2015) 0.97
Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease. FEBS Lett (2012) 0.95
Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study. Clin J Am Soc Nephrol (2015) 0.92
Characterization of circulating APOL1 protein complexes in African Americans. J Lipid Res (2015) 0.92
Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis. Proc Natl Acad Sci U S A (2015) 0.91
BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins. Am J Physiol Cell Physiol (2015) 0.88
APOL1 toxin, innate immunity, and kidney injury. Kidney Int (2015) 0.86
Insights into HLA-G Genetics Provided by Worldwide Haplotype Diversity. Front Immunol (2014) 0.85
Apolipoprotein L1 and Kidney Disease in African Americans. Trends Endocrinol Metab (2016) 0.82
Testing the antagonistic pleiotropy model of schizophrenia susceptibility by analysis of DAOA, PPP1R1B, and APOL1 genes. Psychiatry Res (2010) 0.80
Protein domains of APOL1 and its risk variants. Exp Mol Pathol (2015) 0.80
Glomerular disease: innate immunity-APOL1 interaction. Nat Rev Nephrol (2014) 0.79
APOL1 genetic variants, chronic kidney diseases and hypertension in mixed ancestry South Africans. BMC Genet (2015) 0.77
Association of APOL1 Genotype with Renal Histology among Black HIV-Positive Patients Undergoing Kidney Biopsy. Clin J Am Soc Nephrol (2015) 0.77
Association study of apolipoprotein L-I Lys166Glu and Ile244Met gene variants with obesity in Chinese subjects. Genet Test Mol Biomarkers (2012) 0.75
IgG4-related acute interstitial nephritis and the potential role of mCRP autoantibodies: a case report. Ren Fail (2019) 0.75
Epidemiology investigation and analysis of patients with hemodialysis in Sichuan province of China. Ren Fail (2019) 0.75
Elbasvir/grazoprevir treatment in an HCV-infected peritoneal dialysis patient. Ren Fail (2020) 0.75