K Basler

Author PubWeight™ 68.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Organizing activity of wingless protein in Drosophila. Cell 1993 5.65
2 Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell 1986 4.82
3 Direct and long-range action of a DPP morphogen gradient. Cell 1996 4.33
4 Direct and long-range action of a wingless morphogen gradient. Cell 1996 3.73
5 pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature 1997 3.15
6 Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science 1987 3.06
7 Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 1999 2.70
8 Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science 2001 2.58
9 Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development 1995 2.38
10 Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell 1999 2.33
11 Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science 1996 2.28
12 Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell 1994 1.92
13 An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 1995 1.91
14 Control of compartmental affinity boundaries by hedgehog. Nature 1997 1.91
15 Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. Development 1996 1.86
16 Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development 2000 1.75
17 An absolute requirement for Cubitus interruptus in Hedgehog signaling. Development 2001 1.63
18 Opposing transcriptional outputs of Hedgehog signaling and engrailed control compartmental cell sorting at the Drosophila A/P boundary. Cell 2000 1.60
19 Compartment boundaries: at the edge of development. Trends Genet 1999 1.58
20 Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. Oncogene 2011 1.56
21 Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis. Development 1994 1.44
22 The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic gli-binding sites. Development 2000 1.28
23 Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell 1995 1.26
24 Schnurri mediates Dpp-dependent repression of brinker transcription. Nat Cell Biol 2000 1.22
25 Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker. EMBO J 2000 1.15
26 Brinker requires two corepressors for maximal and versatile repression in Dpp signalling. EMBO J 2001 1.14
27 Distinct and regulated activities of human Gli proteins in Drosophila. Curr Biol 1999 1.07
28 The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. Cell 1992 1.06
29 The Wingless target gene Dfz3 encodes a new member of the Drosophila Frizzled family. Mech Dev 2000 0.99
30 Hedgehog signaling in Drosophila eye and limb development - conserved machinery, divergent roles? Curr Opin Neurobiol 1997 0.93
31 The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Dev Biol 1999 0.93
32 Hedgehog-dependent patterning in the Drosophila eye can occur in the absence of Dpp signaling. Dev Biol 1996 0.92
33 Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate. Trends Genet 1988 0.91
34 Ras1-dependent signaling by ectopically-expressed Drosophila src gene product in the embryo and developing eye. Oncogene 1993 0.82
35 [The development of sleep behavior within the first 5 years of life]. Helv Paediatr Acta 1980 0.80
36 Drosophila ciD encodes a hybrid Pangolin/Cubitus interruptus protein that diverts the Wingless into the Hedgehog signaling pathway. Mech Dev 1998 0.77
37 Mechanisms of positional signalling in the developing eye of Drosophila studied by ectopic expression of sevenless and rough. J Cell Sci Suppl 1990 0.75
38 Cells in search of a signal. Nat Cell Biol 1999 0.75
39 Specification of cell fate in the developing eye of Drosophila. Dev Suppl 1991 0.75
40 Role of receptor tyrosine kinases during Drosophila development. Ciba Found Symp 1990 0.75