Published in Development on August 01, 1995
Stability and nuclear dynamics of the bicoid morphogen gradient. Cell (2007) 5.31
Mechanical feedback as a possible regulator of tissue growth. Proc Natl Acad Sci U S A (2005) 3.79
Planar cell polarity: one or two pathways? Nat Rev Genet (2007) 2.90
Transducing Hedgehog: the story so far. EMBO J (1998) 2.44
A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth. PLoS Biol (2010) 2.08
Shaping morphogen gradients by proteoglycans. Cold Spring Harb Perspect Biol (2009) 1.96
Beadex encodes an LMO protein that regulates Apterous LIM-homeodomain activity in Drosophila wing development: a model for LMO oncogene function. Genes Dev (1998) 1.87
Pattern, growth, and control. Cell (2011) 1.85
A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development. Genes Dev (2002) 1.85
Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus. Genes Dev (1999) 1.79
Hox control of organ size by regulation of morphogen production and mobility. Science (2006) 1.71
The bantam gene regulates Drosophila growth. Genetics (2002) 1.62
Decapentaplegic and growth control in the developing Drosophila wing. Nature (2015) 1.56
Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci (2000) 1.55
A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. EMBO J (1997) 1.52
On the origin and evolutionary diversification of beetle horns. Proc Natl Acad Sci U S A (2007) 1.48
Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube. Philos Trans R Soc Lond B Biol Sci (2008) 1.48
Developmental parameters of cell death in the wing disc of Drosophila. Proc Natl Acad Sci U S A (1997) 1.47
Cell type-specific responses to wingless, hedgehog and decapentaplegic are essential for patterning early eye-antenna disc in Drosophila. PLoS One (2015) 1.41
Limb morphogenesis: connections between patterning and growth. Curr Biol (1997) 1.41
Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility. Proc Natl Acad Sci U S A (2011) 1.37
Regulation of organ growth by morphogen gradients. Cold Spring Harb Perspect Biol (2010) 1.28
Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics (2006) 1.26
Dpp signaling activity requires Pentagone to scale with tissue size in the growing Drosophila wing imaginal disc. PLoS Biol (2011) 1.24
Cell rearrangements, cell divisions and cell death in a migrating epithelial sheet in the abdomen of Drosophila. Development (2009) 1.23
Dpp spreading is required for medial but not for lateral wing disc growth. Nature (2015) 1.18
Cholesterol modification of Hedgehog family proteins. J Clin Invest (2002) 1.17
Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker. EMBO J (2000) 1.15
Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm induction. Genes Dev (1998) 1.14
Do the protocadherins Fat and Dachsous link up to determine both planar cell polarity and the dimensions of organs? Nat Cell Biol (2008) 1.13
Mechanisms of growth and homeostasis in the Drosophila wing. Annu Rev Cell Dev Biol (2009) 1.12
The Drumstick/Lines/Bowl regulatory pathway links antagonistic Hedgehog and Wingless signaling inputs to epidermal cell differentiation. Genes Dev (2005) 1.09
Differential range and activity of various forms of the Hedgehog protein. BMC Dev Biol (2005) 1.07
Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling. EMBO J (1997) 1.06
The control of size in animals: insights from selector genes. Bioessays (2008) 1.05
Sexually dimorphic regulation of the Wingless morphogen controls sex-specific segment number in Drosophila. Proc Natl Acad Sci U S A (2011) 1.04
A gain-of-function screen identifying genes required for growth and pattern formation of the Drosophila melanogaster wing. Genetics (2009) 1.04
Wnt signaling pathways in urological cancers: past decades and still growing. Mol Cancer (2012) 1.03
The G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila. Proc Natl Acad Sci U S A (2007) 1.03
Proximo-distal specification in the wing disc of Drosophila by the nubbin gene. Proc Natl Acad Sci U S A (1997) 1.03
Mutant alleles of the Drosophila trithorax gene produce common and unusual homeotic and other developmental phenotypes. Genetics (1999) 1.02
Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling. Development (2010) 1.01
Drosophila sex combs as a model of evolutionary innovations. Evol Dev (2012) 1.01
How are the sizes of cells, organs, and bodies controlled? PLoS Biol (2003) 1.00
Spatiotemporal mechanisms of morphogen gradient interpretation. Curr Opin Genet Dev (2011) 1.00
Needs and targets for the multi sex combs gene product in Drosophila melanogaster. Genetics (1998) 0.99
Mad is required for wingless signaling in wing development and segment patterning in Drosophila. PLoS One (2009) 0.97
Geometric control of tissue morphogenesis. Biochim Biophys Acta (2009) 0.96
An inwardly rectifying K+ channel is required for patterning. Development (2012) 0.96
Quantification of growth asymmetries in developing epithelia. Eur Phys J E Soft Matter (2009) 0.95
Organ Size Control: Lessons from Drosophila. Dev Cell (2015) 0.95
The small GTPase Rap1 is a modulator of Hedgehog signaling. Dev Biol (2015) 0.94
Ihog and Boi are essential for Hedgehog signaling in Drosophila. Neural Dev (2010) 0.93
A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing. Genetics (2008) 0.93
Control of organ growth by patterning and hippo signaling in Drosophila. Cold Spring Harb Perspect Biol (2015) 0.92
Drosophila Costal1 mutations are alleles of protein kinase A that modulate hedgehog signaling. Genetics (2004) 0.92
TIE-DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster. Development (2013) 0.91
Enhancement of overgrowth by gene interactions in lethal(2)giant discs imaginal discs from Drosophila melanogaster. Genetics (1997) 0.89
The interplay between morphogens and tissue growth. EMBO Rep (2011) 0.89
A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts. Genetics (2008) 0.86
Reciprocal roles for bowl and lines in specifying the peripodial epithelium and the disc proper of the Drosophila wing primordium. Development (2008) 0.84
Drosophila Smad2 opposes Mad signaling during wing vein development. PLoS One (2010) 0.84
Hedgehog signaling in the Drosophila eye and head: an analysis of the effects of different patched trans-heterozygotes. Genetics (2003) 0.83
Cytonemes and the dispersion of morphogens. Wiley Interdiscip Rev Dev Biol (2014) 0.83
Role of knot (kn) in wing patterning in Drosophila. Genetics (1997) 0.82
The specification of a highly derived arthropod appendage, the Drosophila labial palps, requires the joint action of selectors and signaling pathways. Dev Genes Evol (2006) 0.82
DER signaling restricts the boundaries of the wing field during Drosophila development. Proc Natl Acad Sci U S A (2000) 0.82
Notch signaling and developmental cell-cycle arrest in Drosophila polar follicle cells. Mol Biol Cell (2009) 0.82
In vivo analysis of compound activity and mechanism of action using epistasis in Drosophila. J Chem Biol (2010) 0.81
Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules. PLoS Genet (2015) 0.81
The transcriptional co-factor Chip acts with LIM-homeodomain proteins to set the boundary of the eye field in Drosophila. Development (2010) 0.81
A novel interaction between hedgehog and Notch promotes proliferation at the anterior-posterior organizer of the Drosophila wing. Genetics (2010) 0.80
Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1. Elife (2017) 0.80
Mutations in the polycomb group gene polyhomeotic lead to epithelial instability in both the ovary and wing imaginal disc in Drosophila. PLoS One (2010) 0.80
Autism associated gene, engrailed2, and flanking gene levels are altered in post-mortem cerebellum. PLoS One (2014) 0.80
The engrailed story. Genetics (1998) 0.80
The Kto-Skd complex can regulate ptc expression by interacting with Cubitus interruptus (Ci) in the Hedgehog signaling pathway. J Biol Chem (2014) 0.79
A directed mutagenesis screen in Drosophila melanogaster reveals new mutants that influence hedgehog signaling. Genetics (2000) 0.79
Compartment boundaries: sorting cells with tension. Fly (Austin) (2010) 0.79
The effects of weak genetic perturbations on the transcriptome of the wing imaginal disc and its association with wing shape in Drosophila melanogaster. Genetics (2011) 0.79
FijiWings: an open source toolkit for semiautomated morphometric analysis of insect wings. G3 (Bethesda) (2013) 0.78
Genetic interactions among scribbler, Atrophin and groucho in Drosophila uncover links in transcriptional repression. Genetics (2006) 0.78
Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models. Nat Commun (2015) 0.77
The expression of wingless and Engrailed in developing embryos of the mayfly Ephoron leukon (Ephemeroptera: Polymitarcyidae). Dev Genes Evol (2010) 0.77
Precocious expression of the Glide/Gcm glial-promoting factor in Drosophila induces neurogenesis. Genetics (2002) 0.76
JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling. Nat Commun (2017) 0.76
The legacy of Drosophila imaginal discs. Chromosoma (2016) 0.76
Generating Diverse Spinal Motor Neuron Subtypes from Human Pluripotent Stem Cells. Stem Cells Int (2015) 0.76
Hyperplastic discs differentially regulates the transcriptional outputs of hedgehog signaling. Mech Dev (2014) 0.76
Localized JNK signaling regulates organ size during development. Elife (2016) 0.76
De novo transcriptome of the mayfly Cloeon viridulum and transcriptional signatures of Prometabola. PLoS One (2017) 0.75
Inwardly rectifying potassium channels regulate Dpp release in the Drosophila wing disc. Development (2017) 0.75
Organizing activity of wingless protein in Drosophila. Cell (1993) 5.65
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell (1986) 4.82
Direct and long-range action of a DPP morphogen gradient. Cell (1996) 4.33
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature (1998) 4.14
Dual roles for patched in sequestering and transducing Hedgehog. Cell (1996) 4.10
A gene product required for correct initiation of segmental determination in Drosophila. Nature (1981) 3.97
Direct and long-range action of a wingless morphogen gradient. Cell (1996) 3.73
Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature (1994) 3.72
Isolation, structure, and expression of even-skipped: a second pair-rule gene of Drosophila containing a homeo box. Cell (1986) 3.44
RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos. Cell (1991) 3.39
A molecular gradient in early Drosophila embryos and its role in specifying the body pattern. Nature (1987) 3.23
A homoeotic mutation transforming leg to antenna in Drosophila. Nature (1981) 3.19
Genes controlling segmental specification in the Drosophila thorax. Proc Natl Acad Sci U S A (1982) 3.16
pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature (1997) 3.15
Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J (1985) 3.08
Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science (1987) 3.06
cis-acting sequences responsible for anterior localization of bicoid mRNA in Drosophila embryos. Nature (1988) 2.89
Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell (1999) 2.70
Morphogens, compartments, and pattern: lessons from drosophila? Cell (1996) 2.70
Polycomb group proteins and heritable silencing of Drosophila Hox genes. Development (2001) 2.67
Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science (2001) 2.58
RNA recognition and translational regulation by a homeodomain protein. Nature (1996) 2.49
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell (1999) 2.33
Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science (1996) 2.28
Protein kinase A and hedgehog signaling in Drosophila limb development. Cell (1995) 2.22
Regulation of the Ultrabithorax gene of Drosophila by other bithorax complex genes. Cell (1985) 2.19
Role of the esc+ gene product in ensuring the selective expression of segment-specific homeotic genes in Drosophila. J Embryol Exp Morphol (1983) 2.09
Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even-skipped genes. Nature (1987) 2.00
A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube. Mol Cell (2001) 1.99
Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell (1994) 1.92
An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell (1995) 1.91
Control of compartmental affinity boundaries by hedgehog. Nature (1997) 1.91
Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. Development (1996) 1.86
Early role of the esc+ gene product in the determination of segments in Drosophila. Cell (1982) 1.86
Different requirements for homeotic genes in the soma and germ line of Drosophila. Cell (1983) 1.77
Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development (2000) 1.75
An absolute requirement for Cubitus interruptus in Hedgehog signaling. Development (2001) 1.63
Localized surface activity of torso, a receptor tyrosine kinase, specifies terminal body pattern in Drosophila. Genes Dev (1989) 1.61
Opposing transcriptional outputs of Hedgehog signaling and engrailed control compartmental cell sorting at the Drosophila A/P boundary. Cell (2000) 1.60
Compartment boundaries: at the edge of development. Trends Genet (1999) 1.58
Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. Oncogene (2011) 1.56
Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila. Development (1999) 1.56
Near-reciprocal phenotypes caused by inactivation or indiscriminate expression of the Drosophila segmentation gene ftz. Nature (1986) 1.48
Decoding vectorial information from a gradient: sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye. Development (1999) 1.48
Progression of the morphogenetic furrow in the Drosophila eye: the roles of Hedgehog, Decapentaplegic and the Raf pathway. Development (1999) 1.47
Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis. Development (1994) 1.44
Structure of the Drosophila BicaudalD protein and its role in localizing the the posterior determinant nanos. Cell (1989) 1.44
Are cross-regulatory interactions between homoeotic genes functionally significant? Nature (1990) 1.38
In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex. Development (1998) 1.37
The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila. Nature (1993) 1.37
Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila. Nat Cell Biol (2001) 1.30
Delta/Notch and Boss/Sevenless signals act combinatorially to specify the Drosophila R7 photoreceptor. Mol Cell (2001) 1.29
The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic gli-binding sites. Development (2000) 1.28
Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell (1995) 1.26
Bristle patterns and compartment boundaries in the tarsi of Drosophila. J Embryol Exp Morphol (1979) 1.23
Schnurri mediates Dpp-dependent repression of brinker transcription. Nat Cell Biol (2000) 1.22
Similarities between trunk and spätzle, putative extracellular ligands specifying body pattern in Drosophila. Genes Dev (1995) 1.20
Decoding positional information: regulation of the pair-rule gene hairy. Development (1990) 1.19
Further studies of the engrailed phenotype in Drosophila. EMBO J (1982) 1.19
Complementary and mutually exclusive activities of decapentaplegic and wingless organize axial patterning during Drosophila leg development. Cell (1996) 1.18
Down-regulation of the Drosophila morphogen bicoid by the torso receptor-mediated signal transduction cascade. Cell (1993) 1.17
Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker. EMBO J (2000) 1.15
Brinker requires two corepressors for maximal and versatile repression in Dpp signalling. EMBO J (2001) 1.14
Distinct and regulated activities of human Gli proteins in Drosophila. Curr Biol (1999) 1.07
The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. Cell (1992) 1.06
The hedgehog morphogen and gradients of cell affinity in the abdomen of Drosophila. Development (1999) 1.03
Homeotic transformations of the abdominal segments of Drosophila caused by breaking or deleting a central portion of the bithorax complex. J Embryol Exp Morphol (1983) 1.03
hedgehog and engrailed: pattern formation and polarity in the Drosophila abdomen. Development (1999) 1.01
The Wingless target gene Dfz3 encodes a new member of the Drosophila Frizzled family. Mech Dev (2000) 0.99
Different levels of Ras activity can specify distinct transcriptional and morphological consequences in early Drosophila embryos. Development (1997) 0.97
A New Mating Compatibility Locus in PHYSARUM POLYCEPHALUM. Genetics (1979) 0.96
Hedgehog signaling in Drosophila eye and limb development - conserved machinery, divergent roles? Curr Opin Neurobiol (1997) 0.93
The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Dev Biol (1999) 0.93
Spineless-aristapedia: a homeotic gene that does not control the development of specific compartments in Drosophila. Genetics (1982) 0.93
Hedgehog-dependent patterning in the Drosophila eye can occur in the absence of Dpp signaling. Dev Biol (1996) 0.92
Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate. Trends Genet (1988) 0.91
Sequence-specific RNA binding by bicoid. Nature (1997) 0.87
An oncogenic form of human raf can specify terminal body pattern in Drosophila. Mech Dev (1994) 0.85
Ras1-dependent signaling by ectopically-expressed Drosophila src gene product in the embryo and developing eye. Oncogene (1993) 0.82
[The development of sleep behavior within the first 5 years of life]. Helv Paediatr Acta (1980) 0.80
Drosophila ciD encodes a hybrid Pangolin/Cubitus interruptus protein that diverts the Wingless into the Hedgehog signaling pathway. Mech Dev (1998) 0.77
Developmental biology. Fly fishing downstream. Nature (1990) 0.76
Decapentaplegic - hopes held out. Nature (1982) 0.75
A universal genetic key to body plan? Nature (1984) 0.75
Role of receptor tyrosine kinases during Drosophila development. Ciba Found Symp (1990) 0.75
Specification of cell fate in the developing eye of Drosophila. Dev Suppl (1991) 0.75
Cells in search of a signal. Nat Cell Biol (1999) 0.75
Mechanisms of positional signalling in the developing eye of Drosophila studied by ectopic expression of sevenless and rough. J Cell Sci Suppl (1990) 0.75