Y K Fung

Author PubWeight™ 63.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature 1984 5.53
2 Structural evidence for the authenticity of the human retinoblastoma gene. Science 1987 4.67
3 Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science 1989 3.63
4 Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus. Cell 1983 3.45
5 On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses. Proc Natl Acad Sci U S A 1981 3.30
6 Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science 1988 2.83
7 Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung. Oncogene 1988 2.29
8 The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumours. Oncogene 1989 2.02
9 Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol 1985 1.85
10 Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus. J Virol 1981 1.67
11 Inhibition of apoptosis by the retinoblastoma gene product. EMBO J 1995 1.58
12 Cell cycle regulation of nuclear localization of hepatitis B virus core protein. Proc Natl Acad Sci U S A 1993 1.55
13 Tumor induction by direct injection of cloned v-src DNA into chickens. Proc Natl Acad Sci U S A 1983 1.53
14 Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins. Mol Cell Biol 1999 1.43
15 Identification of protein products encoded by the proto-oncogene int-1. Mol Cell Biol 1987 1.38
16 Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. J Virol 1982 1.24
17 Structural alterations of the RB1 gene in human soft tissue tumours. Br J Cancer 1989 1.14
18 Activation of p53 tumor suppressor by hepatitis C virus core protein. Virology 1999 1.08
19 Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization. Cytogenet Cell Genet 1992 1.07
20 Characterization of the cytoplasmic proline-directed protein kinase in proliferative cells and tissues as a heterodimer comprised of p34cdc2 and p58cyclin A. J Biol Chem 1991 1.03
21 Functional outcome of the hand following flexor tendon repair at the 'no man's land'. J Orthop Surg (Hong Kong) 2006 1.00
22 Avian lymphoid leukosis virus infection and DNA integration in the preleukotic bursal tissues: a comparative study of susceptible and resistant lines. Virology 1982 0.97
23 The gene responsible for the development of retinoblastoma and osteosarcoma. Cancer 1988 0.95
24 Effects of nicotine on bone mass and strength in aged female rats. J Orthop Res 2003 0.87
25 Discovery of a regulatory motif that controls the exposure of specific upstream cyclin-dependent kinase sites that determine both conformation and growth suppressing activity of pRb. J Biol Chem 1999 0.87
26 Effects of nicotine on bone mass, turnover, and strength in adult female rats. Calcif Tissue Int 2001 0.84
27 Effects of nicotine on bone and calciotropic hormones in aged ovariectomized rats. J Musculoskelet Neuronal Interact 2002 0.83
28 Studies on the mechanism of butyrate-induced morphological changes in KB cells. Exp Cell Res 1978 0.81
29 The molecular basis of avian retrovirus-induced leukemogenesis. Haematol Blood Transfus 1981 0.81
30 Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI-p53 complexes. Cancer Gene Ther 2001 0.81
31 Engineered mutants of pRB with improved growth suppression potential. Oncogene 1997 0.81
32 Analysis of viral and cellular gene expression during progression and suppression of the transformed phenotype in type 5 adenovirus-transformed rat embryo cells. Oncogene 1991 0.80
33 Effects of nicotine on bone and calciotropic hormones in growing female rats. Calcif Tissue Int 2000 0.79
34 The role of the retinoblastoma gene in breast cancer development. Cancer Treat Res 1992 0.79
35 Depletion of striatal dopamine by the N-oxide of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Neurotoxicology 1991 0.78
36 Coupled down-regulation of the RB retinoblastoma and c-myc genes antecedes cell differentiation: possible role of RB as a "status quo" gene. Eur J Cell Biol 1992 0.78
37 The importance of calcium in amphetamine-induced turning behavior in mice with unilateral nigro-striatal lesions. Neuropharmacology 1980 0.77
38 Regulation of retinoblastoma gene expression in hormone-dependent breast cancer. Endocrinology 1995 0.77
39 Pharmacological effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine receptor system. Brain Res 1986 0.77
40 Nicotine enhances interleukin production of rat splenic T lymphocytes. Immunopharmacol Immunotoxicol 1992 0.76
41 The importance of calcium in the amphetamine-induced stimulation of dopamine synthesis in mouse striata in vivo. J Pharmacol Exp Ther 1982 0.76
42 Microalbuminuria prevalence study in hypertensive type 2 diabetic patients in Malaysia. Med J Malaysia 2006 0.76
43 Acute effect of nicotine on the striatal dopaminergic system in the rat. J Pharm Pharmacol 1986 0.76
44 Effects of systemic administration of nicotine on capillaries in rat oral mucosa. J Oral Pathol Med 1989 0.75
45 An automated method for measurement of circling behavior in the mouse. Pharmacol Biochem Behav 1983 0.75
46 Molecular biology of the human retinoblastoma gene. Cancer Treat Res 1989 0.75
47 Desensitization of finger tip injury. Tech Hand Up Extrem Surg 2001 0.75
48 The differential effects of amphetamine and methylphenidate on the biosynthesis of [3H]dopa from [3H]tyrosine in mouse striata in vivo. J Pharm Pharmacol 1982 0.75
49 In vivo mercury and methyl mercury levels in patients with amalgam restorations. Gen Dent 1990 0.75
50 Effects of systemic and topical nicotine on pulpal blood flow in dogs. Endod Dent Traumatol 1993 0.75
51 Amphetamine-induced circling behaviour in MPTP-lesioned mice. J Pharm Pharmacol 1985 0.75
52 Stereoselective syntheses of the trans-decahydroquinoline-5-carboxylic acid epimers. Diastereomeric zwitterionic probes of gamma-aminobutyric acid related biological properties in vitro and in vivo. J Med Chem 1986 0.75
53 Effect of chronic administration of nicotine or cocaine on steroidogenesis in rat adrenocortical cells. J Pharm Pharmacol 1991 0.75
54 Antagonistic effects of isofloxythepin on dopamine D1 and D2 receptors and behaviors in rats. Gen Pharmacol 1997 0.75
55 An in-vivo method for testing drugs that influence striatal dopaminergic functions. Pharmacol Biochem Behav 1983 0.75
56 BehavioraL and biochemical changes caused by muscimol in mice withdrawN from haloperidol administration. Neuropharmacology 1982 0.75
57 The effect of dopamine uptake blocking agents on the amphetamine-induced circling behavior in mice with unilateral nigro-striatal lesions. J Pharmacol Exp Ther 1980 0.75
58 Modulation of nigrostriatal dopaminergic transmission by antisense oligodeoxynucleotide against brain-derived neurotrophic factor. Neurochem Res 1998 0.75
59 Modulation of apomorphine-induced climbing behavior by estradiol. Pharmacol Biochem Behav 1986 0.75
60 Effects of topical and systemic nicotine on gingival blood flow in dogs. J Dent Res 1991 0.75
61 The selective inhibitory effect of EGTA on the circling behaviour produced by amphetamine but not methylphenidate in mice lesioned with 6-hydroxydopamine. J Pharm Pharmacol 1980 0.75
62 An in vivo method for testing GABAergic compounds. Pharmacol Biochem Behav 1982 0.75
63 Effect of calcium on locomotor activity of mice. Psychopharmacology (Berl) 1980 0.75
64 Stereostructure-activity relationships of the GABA-containing cis-decahydroquinoline-5-carboxylic acids; intracerebroventricular studies in mice. Res Commun Chem Pathol Pharmacol 1983 0.75