Published in Proc Natl Acad Sci U S A on June 01, 1981
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc Natl Acad Sci U S A (1982) 20.55
Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 5.80
Differential expression of the amv gene in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 4.37
Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus. EMBO J (1986) 4.08
Two human c-onc genes are located on the long arm of chromosome 8. Proc Natl Acad Sci U S A (1982) 3.02
At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses. Proc Natl Acad Sci U S A (1982) 2.84
Two modes of c-myb activation in virus-induced mouse myeloid tumors. Mol Cell Biol (1986) 2.57
Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. Mol Cell Biol (1989) 2.53
Viral integration near c-myc in 10-20% of mcf 247-induced AKR lymphomas. Proc Natl Acad Sci U S A (1984) 2.44
Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors. Proc Natl Acad Sci U S A (1984) 2.02
Leukemogenesis by bovine leukemia virus: proviral DNA integration and lack of RNA expression of viral long terminal repeat and 3' proximate cellular sequences. Proc Natl Acad Sci U S A (1982) 2.02
Patterns of proviral insertion and deletion in avian leukosis virus-induced lymphomas. J Virol (1986) 1.93
Rearrangement of a DNA sequence homologous to a cell-virus junction fragment in several Moloney murine leukemia virus-induced rat thymomas. Proc Natl Acad Sci U S A (1984) 1.93
Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Mol Cell Biol (1986) 1.90
Gene expression from transcriptionally disabled retroviral vectors. Proc Natl Acad Sci U S A (1987) 1.89
Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol (1985) 1.85
Identification of cellular promoters by using a retrovirus promoter trap. J Virol (1989) 1.79
Molecular analysis of the c-myc locus in normal tissue and in avian leukosis virus-induced lymphomas. J Virol (1982) 1.70
Nucleotide sequences of the murine retrovirus Friend SFFVp long terminal repeats: identification of a structure with extensive dyad symmetry 5' to the TATA box. Nucleic Acids Res (1982) 1.70
High-frequency transduction of c-erbB in avian leukosis virus-induced erythroblastosis. J Virol (1985) 1.69
Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes. Mol Cell Biol (1984) 1.64
c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proc Natl Acad Sci U S A (1985) 1.62
Rapid induction of B-cell lymphomas: insertional activation of c-myb by avian leukosis virus. J Virol (1988) 1.61
Retrovirus long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci U S A (1982) 1.61
Tumor induction by direct injection of cloned v-src DNA into chickens. Proc Natl Acad Sci U S A (1983) 1.53
Enhancer activity correlates with the oncogenic potential of avian retroviruses. EMBO J (1985) 1.52
Clonal analysis of early and late stages of erythroleukemia induced by molecular clones of integrated spleen focus-forming virus. Proc Natl Acad Sci U S A (1981) 1.46
Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene. J Virol (1986) 1.46
Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region. J Virol (1987) 1.42
5' long terminal repeats of myc-associated proviruses appear structurally intact but are functionally impaired in tumors induced by avian leukosis viruses. J Virol (1987) 1.25
A retroviral provirus closely associated with the Ren-2 gene of DBA/2 mice. Nucleic Acids Res (1984) 1.25
Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. J Virol (1982) 1.24
Transcription of three c-myc exons is enhanced in chicken bursal lymphoma cell lines. Proc Natl Acad Sci U S A (1985) 1.23
Unique long terminal repeat U3 sequences distinguish exogenous jaagsiekte sheep retroviruses associated with ovine pulmonary carcinoma from endogenous loci in the sheep genome. J Virol (1996) 1.22
Integration of type B retroviral DNA in virus-induced primary murine thymic lymphomas. J Virol (1984) 1.16
Preferential selection of human T-cell leukemia virus type 1 provirus lacking the 5' long terminal repeat during oncogenesis. J Virol (2007) 1.10
Sequences outside of the long terminal repeat determine the lymphomogenic potential of Rous-associated virus type 1. J Virol (1985) 1.08
B-lymphoma induction by reticuloendotheliosis virus: characterization of a mutated chicken syncytial virus provirus involved in c-myc activation. J Virol (1987) 1.07
Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript. EMBO J (1986) 1.06
Features of the chicken c-myc gene that influence the structure of c-myc RNA in normal cells and bursal lymphomas. Mol Cell Biol (1986) 1.00
Isolation of 16L virus: a rapidly transforming sarcoma virus from an avian leukosis virus-induced sarcoma. Proc Natl Acad Sci U S A (1982) 0.99
Human cytomegalovirus (strain AD169) contains sequences related to the avian retrovirus oncogene v-myc. Proc Natl Acad Sci U S A (1983) 0.98
Transcriptional activation of cKi-ras proto-oncogene resulting from retroviral promoter insertion. Nucleic Acids Res (1989) 0.95
Transcriptional interaction between retroviral long terminal repeats (LTRs): mechanism of 5' LTR suppression and 3' LTR promoter activation of c-myc in avian B-cell lymphomas. J Virol (1992) 0.95
Mechanisms of oncogenesis by subgroup F avian leukosis viruses. J Virol (1984) 0.95
Frequent partial deletion of human adult T-cell leukemia virus type I proviruses in experimental transmission: pattern and possible implication. J Virol (1986) 0.94
Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia. J Virol (1989) 0.92
Selection for c-myc integration sites in polyclonal T-cell lymphomas. J Virol (2002) 0.92
Susceptibility to erbB-induced erythroblastosis is a dominant trait of 151 chickens. J Virol (1985) 0.88
Avian proto-myc genes promoted by defective or nondefective retroviruses are single-hit transforming genes in primary cells. Proc Natl Acad Sci U S A (1989) 0.87
Retroviral activation of interleukin 2 gene in a gibbon ape T cell lymphoma line. J Exp Med (1986) 0.82
Deletion in the 3' pol sequence correlates with aberration of RNA expression in certain replication-defective avian sarcoma viruses. J Virol (1985) 0.82
Infrequent involvement of c-fos in avian leukosis virus-induced nephroblastoma. J Virol (1990) 0.81
Sites of retroviral DNA integration: From basic research to clinical applications. Crit Rev Biochem Mol Biol (2015) 0.80
Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions. Environ Health Perspect (1990) 0.75
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature (1981) 17.31
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion. Cell (1981) 8.69
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell (1981) 6.98
Sequence of retrovirus provirus resembles that of bacterial transposable elements. Nature (1980) 5.95
Identification of a functional promoter in the long terminal repeat of Rous sarcoma virus. Cell (1980) 5.51
The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses. Cell (1977) 5.23
Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. J Virol (1973) 3.62
Recombinants between endogenous and exogenous avian tumor viruses: role of the C region and other portions of the genome in the control of replication and transformation. J Virol (1980) 2.93
Subgenomic, cellular Rous sarcoma virus RNAs contain oligonucleotides from the 3' half and the 5' terminus of virion RNA. Nature (1977) 2.53
Unusual features in the nucleotide sequence of a cDNA clone derived from the common region of avian sarcoma virus messenger RNA. Proc Natl Acad Sci U S A (1980) 2.45
Electron microscope studies of tumor virus RNA. Cold Spring Harb Symp Quant Biol (1975) 2.30
The vertebrate homolog of the putative transforming gene of avian myelocytomatosis virus: characteristics of the DNA locus and its RNA transcript. Virology (1980) 2.22
Characterization of DNA complementary to nucleotide sequences at the 5'-terminus of the avian sarcoma virus genome. Virology (1977) 2.16
Nucleotide sequence relationships between the genomes of an endogenous and an exogenous avian tumor virus. J Virol (1978) 2.01
Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virus. J Mol Biol (1980) 1.70
Production of unique C-type viruses by chicken cells grown in bromodeoxyuridine. Virology (1976) 1.70
Pathogenesis of avian lymphoid leukosis. I. Histogenesis. J Natl Cancer Inst (1968) 1.54
Inheritance and expression of chicken genes that are related to avian leukosis sarcoma virus genes. Curr Top Microbiol Immunol (1978) 1.54
Organization of shared and unshared sequences in the genomes of chicken endogenous and sarcoma viruses. Cell (1977) 1.36
Viral DNA in bursal lymphomas induced by avian leukosis viruses. J Virol (1980) 1.30
Chromosomal localization of ev-1, a frequently occurring endogenous retrovirus locus in white Leghorn chickens, by in situ hybridization. J Virol (1980) 1.23
Lymphomas resembling lymphoid leukosis in chickens inoculated with reticuloendotheliosis virus. Int J Cancer (1979) 1.01
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell (1978) 7.46
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell (1981) 6.98
Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature (1984) 5.53
Structural evidence for the authenticity of the human retinoblastoma gene. Science (1987) 4.67
Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis. J Mol Biol (1976) 4.65
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. J Mol Biol (1978) 4.04
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science (1989) 3.63
Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus. Cell (1983) 3.45
RD-114, baboon, and woolly monkey viral RNA's compared in size and structure. Cell (1976) 3.20
Interaction between retroviral U5 RNA and the T psi C loop of the tRNA(Trp) primer is required for efficient initiation of reverse transcription. J Virol (1992) 3.06
c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor. Cell (1985) 3.00
An electron microscope study of Sindbis virus RNA. Cold Spring Harb Symp Quant Biol (1974) 2.99
Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science (1988) 2.83
A consensus linkage map of the chicken genome. Genome Res (2000) 2.79
Structure, subunit composition, and molecular weight of RD-114 RNA. J Virol (1975) 2.66
Electron microscope studies of tumor virus RNA. Cold Spring Harb Symp Quant Biol (1975) 2.30
Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung. Oncogene (1988) 2.29
Kaposi's sarcoma-associated herpesvirus encodes a bZIP protein with homology to BZLF1 of Epstein-Barr virus. J Virol (1999) 2.24
Characterization of DNA complementary to nucleotide sequences adjacent to poly(A) at the 3'-terminus of the avian sarcoma virus genome. Virology (1977) 2.18
CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res (1996) 2.18
Observations on the nature of a genetic cellular resistance to avian tumor viruses. J Natl Cancer Inst (1968) 2.17
Characterization of DNA complementary to nucleotide sequences at the 5'-terminus of the avian sarcoma virus genome. Virology (1977) 2.16
Specific integration of REV proviruses in avian bursal lymphomas. Nature (1981) 2.11
Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells. Nature (1998) 2.08
The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumours. Oncogene (1989) 2.02
Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation. Proc Natl Acad Sci U S A (1990) 1.95
Host gene control of endogenous avian leukosis virus production. Virology (1974) 1.94
Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol (1985) 1.85
Evidence of independent origin of multiple tumors from patients with prostate cancer. J Natl Cancer Inst (1998) 1.81
Marek disease virus encodes a basic-leucine zipper gene resembling the fos/jun oncogenes that is highly expressed in lymphoblastoid tumors. Proc Natl Acad Sci U S A (1992) 1.78
CWR22: androgen-dependent xenograft model derived from a primary human prostatic carcinoma. Cancer Res (1994) 1.77
Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem J (1997) 1.72
Production of unique C-type viruses by chicken cells grown in bromodeoxyuridine. Virology (1976) 1.70
Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells. Proc Natl Acad Sci U S A (1998) 1.70
Altered expression of RET proto-oncogene product in prostatic intraepithelial neoplasia and prostate cancer. J Natl Cancer Inst (1998) 1.68
Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus. J Virol (1981) 1.67
A tyrosine kinase profile of prostate carcinoma. Proc Natl Acad Sci U S A (1996) 1.67
Ten genetic loci in the chicken that contain structural genes for endogenous avian leukosis viruses. Cold Spring Harb Symp Quant Biol (1980) 1.63
c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proc Natl Acad Sci U S A (1985) 1.62
Signaling network of the Btk family kinases. Oncogene (2000) 1.58
Inhibition of apoptosis by the retinoblastoma gene product. EMBO J (1995) 1.58
Cell cycle regulation of nuclear localization of hepatitis B virus core protein. Proc Natl Acad Sci U S A (1993) 1.55
The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus. Proc Natl Acad Sci U S A (2000) 1.55
Tumor induction by direct injection of cloned v-src DNA into chickens. Proc Natl Acad Sci U S A (1983) 1.53
Hierarchical cleavage of focal adhesion kinase by caspases alters signal transduction during apoptosis of intestinal epithelial cells. Gastroenterology (2001) 1.52
Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol (2001) 1.46
Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src. Mol Cell Biol (1985) 1.46
Size, subunit composition, and secondary structure of the Friend virus genome. J Virol (1976) 1.45
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol (2000) 1.44
Nucleolar and nuclear localization properties of a herpesvirus bZIP oncoprotein, MEQ. J Virol (1997) 1.43
Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins. Mol Cell Biol (1999) 1.43
Transgenic chickens: insertion of retroviral genes into the chicken germ line. Virology (1987) 1.42
DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes. Mol Cell Biol (1987) 1.41
Transforming potential of the herpesvirus oncoprotein MEQ: morphological transformation, serum-independent growth, and inhibition of apoptosis. J Virol (1998) 1.39
Identification of protein products encoded by the proto-oncogene int-1. Mol Cell Biol (1987) 1.38
MCF-10A-NeoST: a new cell system for studying cell-ECM and cell-cell interactions in breast cancer. Clin Cancer Res (2001) 1.36
Genetic control of RAV-O production in chickens. Virology (1977) 1.35
Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J Virol (2001) 1.34
The identification of monoclonality in human aberrant crypt foci. Cancer Res (1999) 1.34
Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain. Nat Cell Biol (2001) 1.34
Low oncogenic potential of avian endogenous RNA tumor virus infection or expression. J Natl Cancer Inst (1975) 1.31
Oncogenicity of avian leukosis viruses of different subgroups and of mutants of sarcoma viruses. Infect Immun (1977) 1.29
Helper-independent retrovirus vectors with Rous-associated virus type O long terminal repeats. J Virol (1988) 1.29
ErbB kinases and NDF signaling in human prostate cancer cells. Oncogene (1997) 1.28
Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells. J Biol Chem (2001) 1.27
Development of a genetic map of the chicken with markers of high utility. Poult Sci (1995) 1.27
Two loci controlling genetic cellular resistance to avian leukosis-sarcoma viruses. J Virol (1967) 1.27
Structural analysis and transcriptional mapping of the Marek's disease virus gene encoding pp38, an antigen associated with transformed cells. J Virol (1991) 1.26
Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. J Virol (1982) 1.24
Retrovirus insertion into herpesvirus in vitro and in vivo. Proc Natl Acad Sci U S A (1992) 1.22
MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway. Oncogene (2001) 1.22
Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus. J Virol (1985) 1.20
A complete description of the EGF-receptor exon structure: implication in oncogenic activation and domain evolution. Oncogene (1993) 1.20
Transactivation activity of Meq, a Marek's disease herpesvirus bZIP protein persistently expressed in latently infected transformed T cells. J Virol (1995) 1.19
Low incidence of lymphoid tumors in chickens continuously producing endogenous virus. Avian Dis (1980) 1.19
Induction of neoplasms by subgroup E recombinants of exogenous and endogenous avian retroviruses (Rous-associated virus type 60). J Virol (1980) 1.18
Origin and prognostic value of circulating KRAS mutations in lung cancer patients. Cancer Lett (2007) 1.17
Rous-associated virus 1-induced erythroleukemic cells exhibit a weakly transformed phenotype in vitro and release c-erbB-containing retroviruses unable to transform fibroblasts. J Virol (1986) 1.16
Structural alterations of the RB1 gene in human soft tissue tumours. Br J Cancer (1989) 1.14
Gene insertion into the chicken germ line by retroviruses. Poult Sci (1986) 1.13
Interaction of genes controlling resistance to RSV(RAV-O). Virology (1973) 1.13
Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase. Mol Cell Biol (1995) 1.13
Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. Int J Cancer (1999) 1.12