Published in ACS Sens on February 09, 2016
Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotechnol (2005) 9.57
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol (1999) 8.46
Molecular imaging in cancer. Science (2006) 5.01
Fluorescence lifetime measurements and biological imaging. Chem Rev (2010) 3.99
Fluorescence molecular imaging. Annu Rev Biomed Eng (2006) 3.70
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct. Circ Res (2007) 2.77
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. Gastroenterology (2002) 2.64
Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation (2005) 2.45
Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model. Radiology (2001) 2.24
Near-infrared optical imaging of protease activity for tumor detection. Radiology (1999) 1.97
Target-cancer-cell-specific activatable fluorescence imaging probes: rational design and in vivo applications. Acc Chem Res (2010) 1.74
Time resolved fluorescence tomography of turbid media based on lifetime contrast. Opt Express (2006) 1.70
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum (2004) 1.55
Lifetime-based tomographic multiplexing. J Biomed Opt (2010) 1.45
Developing a peptide-based near-infrared molecular probe for protease sensing. Bioconjug Chem (2004) 1.42
A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology (1993) 1.32
Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes. Curr Opin Chem Biol (2011) 1.31
Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes. Invest Radiol (2005) 1.22
Noninvasive quantitative tomography of the therapeutic response to dexamethasone in ovalbumin-induced murine asthma. J Pharmacol Exp Ther (2009) 1.08
Proteolysis: a biological process adapted in drug delivery, therapy, and imaging. Bioconjug Chem (2009) 1.07
Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment. Neoplasia (2002) 1.03
Use of fluorescent imaging to investigate pathological protease activity. Curr Opin Drug Discov Devel (2008) 0.91
Engineering NIR dyes for fluorescent lifetime contrast. Conf Proc IEEE Eng Med Biol Soc (2009) 0.88
Protected Graft Copolymer (PGC) in Imaging and Therapy: A Platform for the Delivery of Covalently and Non-Covalently Bound Drugs. Theranostics (2012) 0.88
A long-circulating co-polymer in "passive targeting" to solid tumors. J Drug Target (1997) 0.88
Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential. Top Magn Reson Imaging (2008) 0.87
Prediction of the viscosity radius and the size exclusion chromatography behavior of PEGylated proteins. Bioconjug Chem (2004) 0.87
In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium. J Biomed Opt (2012) 0.86
Optical tomographic imaging of near infrared imaging agents quantifies disease severity and immunomodulation of experimental autoimmune encephalomyelitis in vivo. J Neuroinflammation (2013) 0.85
Bacterial adhesion on hybrid cationic nanoparticle-polymer brush surfaces: ionic strength tunes capture from monovalent to multivalent binding. Colloids Surf B Biointerfaces (2011) 0.83
Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and α(v)β(3) Integrin. Int J Mol Imaging (2012) 0.81
It is all about proteases: from drug delivery to in vivo imaging and photomedicine. Curr Med Chem (2011) 0.81
Molecular probes for fluorescence lifetime imaging. Bioconjug Chem (2015) 0.80
Biological activities of polyethylene-glycol immunoglobulin conjugates. Resistance to enzymatic degradation. J Immunol Methods (1992) 0.80
Spectroscopic study of a novel bis(heptamethine cyanine) dye and its interaction with human serum albumin. Appl Spectrosc (2005) 0.79
Detection of protease activity in cells and animals. Biochim Biophys Acta (2015) 0.77
The three-dimensional context of a double helix determines the fluorescence of the internucleoside-tethered pair of fluorophores. Mol Biosyst (2013) 0.75