Published in Am J Hum Genet on March 01, 1988
Genetic causes of high and low serum HDL-cholesterol. J Lipid Res (2010) 1.55
Genetic determination of plasma apolipoprotein AI in a population-based sample. Am J Hum Genet (1989) 1.29
Estimation of Hardy-Weinberg and pairwise disequilibrium in the apolipoprotein AI-CIII-AIV gene cluster. Am J Hum Genet (1991) 0.99
Evidence for linkage of the apolipoprotein A-II locus to plasma apolipoprotein A-II and free fatty acid levels in mice and humans. Proc Natl Acad Sci U S A (1993) 0.86
Variation at the apolipoprotein (apo) AI-CIII-AIV gene cluster and apo B gene loci is associated with lipoprotein and apolipoprotein levels in Italian children. Am J Hum Genet (1990) 0.80
Four DNA polymorphisms in the LDL receptor gene: their genetic relationship and use in the study of variation at the LDL receptor locus. J Med Genet (1988) 0.79
DNA sequence variants in the G gamma-, A gamma-, delta- and beta-globin genes of man. Cell (1979) 15.74
High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med (1977) 15.39
Fine structure genetic analysis of a beta-globin promoter. Science (1986) 6.36
The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study. Lancet (1977) 5.10
A comprehensive evaluation of the heparin-manganese precipitation procedure for estimating high density lipoprotein cholesterol. J Lipid Res (1978) 4.84
Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes. Proc Natl Acad Sci U S A (1985) 4.04
Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet (1985) 3.81
Localization of the structural gene for human apolipoprotein A-I on the long arm of human chromosome 11. Proc Natl Acad Sci U S A (1984) 3.70
DNA polymorphism adjacent to human apoprotein A-1 gene: relation to hypertriglyceridaemia. Lancet (1983) 2.28
Deoxyribonucleic acid polymorphism in the apolipoprotein A-1-C-III gene cluster. Association with hypertriglyceridemia. J Clin Invest (1985) 1.73
Apolipoprotein A-I gene polymorphism associated with premature coronary artery disease and familial hypoalphalipoproteinemia. N Engl J Med (1986) 1.70
Chromosomal localization of the human apoprotein CI gene and of a polymorphic apoprotein AII gene. Biochem Biophys Res Commun (1984) 1.69
A study of DNA polymorphisms around the human apolipoprotein AI gene in hyperlipidaemic and normal individuals. Clin Genet (1985) 1.62
Apolipoprotein A-I as a marker of angiographically assessed coronary-artery disease. N Engl J Med (1983) 1.56
Lipoprotein apoprotein metabolism. J Lipid Res (1978) 1.48
Associations of serum high density lipoprotein and total cholesterol with total, cardiovascular, and cancer mortality in a 7-year prospective study of 10 000 men. Lancet (1981) 1.31
Apolipoprotein E phenotypes and hyperlipidemia. Hum Genet (1984) 1.26
High-density lipoprotein composition is altered by a common DNA polymorphism adjacent to apoprotein AII gene in man. Lancet (1985) 1.26
Polymorphisms in the apolipoprotein AI-CIII gene complex. Mol Biol Med (1986) 1.07
Serum-high-density-lipoprotein and atherosclerotic heart-disease. Lancet (1976) 0.99
Multivariate analyses of serum apolipoproteins and risk factors in relation to acute myocardial infarction. Arteriosclerosis (1981) 0.99
The human apolipoprotein A-II gene is located on chromosome 1. Biochem Biophys Res Commun (1984) 0.97
In vitro activation of the enzymic activity of hepatic lipase by apoA-II. FEBS Lett (1981) 0.90
DNA polymorphisms around the apo AI gene in normal and hyperlipidaemic individuals selected for a twin study. Clin Genet (1986) 0.86
The sequence of the human genome. Science (2001) 101.55
Graphic representation of pain. Pain (1976) 14.25
Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet (1993) 9.34
Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease. Lancet (1975) 9.00
A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine. Cell (1987) 7.25
Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods. Nucleic Acids Res (2001) 6.49
Fibrinogen, viscosity, and white blood cell count are major risk factors for ischemic heart disease. The Caerphilly and Speedwell collaborative heart disease studies. Circulation (1991) 5.66
The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study. Lancet (1977) 5.10
Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis (2000) 4.88
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet (1999) 4.48
Relationship between occupations and asbestos-fibre content of the lungs in patients with pleural mesothelioma, lung cancer, and other diseases. Thorax (1977) 4.35
Knowledge-based indexing of the medical literature: the Indexing Aid Project. J Am Soc Inf Sci (1987) 4.15
A randomized trial of group outpatient visits for chronically ill older HMO members: the Cooperative Health Care Clinic. J Am Geriatr Soc (1997) 4.09
Choline containing metabolites during cell transfection: an insight into magnetic resonance spectroscopy detectable changes. FEBS Lett (2001) 3.88
Nest predation increases with parental activity: separating nest site and parental activity effects. Proc Biol Sci (2000) 3.73
Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med (2001) 3.55
Errors in the polymerase chain reaction. Nucleic Acids Res (1988) 3.52
Technique to improve chronic motor deficit after stroke. Arch Phys Med Rehabil (1993) 3.50
The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro. FEBS Lett (1996) 3.21
Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. J Biol Chem (1994) 3.18
Learning of visceral and glandular responses. Science (1969) 3.13
Some observations on the diagnosis of rectal gonorrhoea in both sexes using a selective culture medium. Br J Vener Dis (1966) 3.12
emm typing and validation of provisional M types for group A streptococci. Emerg Infect Dis (1999) 3.12
Immunostimulant therapy with levamisole for rheumatoid arthritis. Lancet (1976) 3.07
Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins. Science (1983) 2.97
Four new anti-inflammatory drugs: responses and variations. Br Med J (1976) 2.84
Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. Br Med J (1974) 2.84
Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics. J Med Genet (2008) 2.81
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. Circulation (2005) 2.77
Human CRP gene polymorphism influences CRP levels: implications for the prediction and pathogenesis of coronary heart disease. Arterioscler Thromb Vasc Biol (2003) 2.63
Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel. J Intern Med (2006) 2.55
Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues. Nature (1985) 2.49
Vertical or horizontal visual analogue scales. Ann Rheum Dis (1979) 2.49
Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B. Proc Natl Acad Sci U S A (2001) 2.44
Treatment of acquired aphasia: speech therapists and volunteers compared. J Neurol Neurosurg Psychiatry (1982) 2.43
Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor. Nature (1983) 2.41
Extent of underdiagnosis of familial hypercholesterolaemia in routine practice: prospective registry study. BMJ (2000) 2.40
Cimetidine and HDL cholesterol. Lancet (1983) 2.40
Electrophoresis for genotyping: microtiter array diagonal gel electrophoresis on horizontal polyacrylamide gels, hydrolink, or agarose. Anal Biochem (1994) 2.38
Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression. J Biol Chem (1996) 2.36
Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues. Nature (1985) 2.29
Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysms. Circulation (2001) 2.29
Alternative to current MPH degree program. Health Serv Rep (1972) 2.28
A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3. Nat Genet (1994) 2.26
Autobiographical memory in depression: state or trait marker? Br J Psychiatry (1993) 2.24
Slow virus visna: reproduction in vitro of virus from extrachromosomal DNA. Proc Natl Acad Sci U S A (1984) 2.24
Controlled trial of a home-care service for acute stroke patients. Lancet (1985) 2.19
Randomized controlled trial of brief cognitive behaviour therapy versus treatment as usual in recurrent deliberate self-harm: the POPMACT study. Psychol Med (2003) 2.16
Sequence of a cDNA clone encoding human preproinsulin-like growth factor II. Nature (1984) 2.13
Gallbladder disease. Prevalence in a South Wales industrial town. N Engl J Med (1976) 2.12
Prevention of relapse in residual depression by cognitive therapy: a controlled trial. Arch Gen Psychiatry (1999) 2.12
Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol (2008) 2.11
Sleep in patients with remitted bipolar disorders: a meta-analysis of actigraphy studies. Acta Psychiatr Scand (2014) 2.10
Malaria susceptibility and CD36 mutation. Nature (2000) 2.07
An in vitro system for the editing of apolipoprotein B mRNA. Cell (1989) 2.07
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1. J Lipid Res (2000) 2.05
Update and analysis of the University College London low density lipoprotein receptor familial hypercholesterolemia database. Ann Hum Genet (2008) 2.05
Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism. J Biol Chem (1994) 2.04
Psychological treatments for depression. An update. Br J Psychiatry (1995) 2.02
Effect of tobacco and alcohol consumption on the Langerhans cell population of human lingual epithelium determined using a monoclonal antibody against HLADR. J Oral Pathol Med (1991) 2.00
Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro. J Biol Chem (1996) 1.98
A meta-analytic evaluation of the polymerase chain reaction for the diagnosis of HIV infection in infants. JAMA (1996) 1.97
Evaluation of effects of unmodified niacin on fasting and postprandial plasma lipids in normolipidemic men with hypoalphalipoproteinemia. Am J Med (1994) 1.96
An operant approach to rehabilitation medicine: overcoming learned nonuse by shaping. J Exp Anal Behav (1994) 1.96
Epidural analgesia for pain relief following hip or knee replacement. Cochrane Database Syst Rev (2003) 1.96
Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery. Arterioscler Thromb Vasc Biol (2001) 1.96
Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93
The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase. J Biol Chem (1993) 1.93
Letter: High-density lipoprotein and atherosclerosis. Lancet (1975) 1.93
Accidental intra-arterial injection via the venous limb of a dual pressure transducer system. Anaesthesia (2000) 1.92
Increased incidence of neoplasia of the digestive tract in men with persistent activation of the coagulant pathway. J Thromb Haemost (2004) 1.91
Plasma triglyceride and high density lipoprotein cholesterol as predictors of ischaemic heart disease in British men. The Caerphilly and Speedwell Collaborative Heart Disease Studies. Br Heart J (1992) 1.88
Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis. Am Heart J (1987) 1.88
Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology. J Psychopharmacol (2005) 1.88
DNA sequence of the human apolipoprotein B gene. DNA (1987) 1.88
Co-occurring severe mental illness and substance use disorders: a review of recent research. Psychiatr Serv (1999) 1.87
Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site. Cell (1995) 1.86
Role of genetic variation at the fibrinogen locus in determination of plasma fibrinogen concentrations. Lancet (1987) 1.85
Prevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant. Cochrane Database Syst Rev (2005) 1.84
Genetics of inflammation and risk of coronary artery disease: the central role of interleukin-6. Eur Heart J (2000) 1.83
Regulation of macrophage activation. Cell Mol Life Sci (2003) 1.83
Relation of angiographically defined coronary artery disease to plasma lipoprotein subfractions and apolipoproteins. Br Med J (Clin Res Ed) (1981) 1.80
Screening for hypercholesterolaemia versus case finding for familial hypercholesterolaemia: a systematic review and cost-effectiveness analysis. Health Technol Assess (2000) 1.80
Toxoplasmosis in heart and heart and lung transplant recipients. J Clin Pathol (1989) 1.78
Human gene for physical performance. Nature (1998) 1.78
RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA. Biochim Biophys Acta (2000) 1.77
Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk. J Med Genet (2006) 1.76
Accuracy of subjective measurements made with or without previous scores: an important source of error in serial measurement of subjective states. Ann Rheum Dis (1979) 1.73
Use of the buccal fat pad as a pedicled graft. J Oral Maxillofac Surg (1986) 1.73
The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life. J Lipid Res (1989) 1.72
Quality of life before and after intensive care. Anaesthesia (2005) 1.72
Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71
An articular index for the assessment of osteoarthritis. Ann Rheum Dis (1981) 1.70
The Bristol Shared Care Glaucoma Study: reliability of community optometric and hospital eye service test measures. Br J Ophthalmol (1999) 1.70
Chromosomal localization of the human apoprotein CI gene and of a polymorphic apoprotein AII gene. Biochem Biophys Res Commun (1984) 1.69
Complete cDNA and derived protein sequence of human apolipoprotein B-100. Nucleic Acids Res (1986) 1.68
A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication. Arch Gen Psychiatry (2000) 1.68
Relationship between markers of activated coagulation, their correlation with inflammation, and association with coronary heart disease (NPHSII). J Thromb Haemost (2007) 1.67
Sequence requirements for the editing of apolipoprotein B mRNA. J Biol Chem (1991) 1.66
A common DNA polymorphism of the low-density lipoprotein (LDL) receptor gene and its use in diagnosis. Lancet (1985) 1.64