Published in J Biol Chem on January 25, 1989
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Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide. Biochem J (1991) 1.68
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Reaction of chromium(VI) with glutathione or with hydrogen peroxide: identification of reactive intermediates and their role in chromium(VI)-induced DNA damage. Environ Health Perspect (1991) 1.13
Efficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells. Chem Res Toxicol (2010) 1.04
Copper and iron are mobilized following myocardial ischemia: possible predictive criteria for tissue injury. Proc Natl Acad Sci U S A (1993) 1.01
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Mechanism of copper-mediated inactivation of herpes simplex virus. Antimicrob Agents Chemother (1997) 0.95
Metal contaminants promote degradation of lipid/DNA complexes during lyophilization. Biochim Biophys Acta (2006) 0.92
The spectrum of mutations generated by passage of a hydrogen peroxide damaged shuttle vector plasmid through a mammalian host. Nucleic Acids Res (1989) 0.91
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DNA cleavage induced by glycation of Cu,Zn-superoxide dismutase. Biochem J (1994) 0.89
Repair of DNA lesions induced by hydrogen peroxide in the presence of iron chelators in Escherichia coli: participation of endonuclease IV and Fpg. J Bacteriol (2000) 0.88
Chemical cleavage of plasmid DNA by glutathione in the presence of Cu(II) ions. The Cu(II)-thiol system for DNA strand scission. Biochem J (1991) 0.87
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases. J Biol Chem (2012) 0.84
Effect of Metals on the Lytic Cycle of the Coccolithovirus, EhV86. Front Microbiol (2012) 0.83
DNA cleavage and detection of DNA radicals formed from hydralazine and copper (II) by ESR and immuno-spin trapping. Chem Res Toxicol (2014) 0.81
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Oxidative damage of DNA induced by the reaction of methylglyoxal with lysine in the presence of ferritin. BMB Rep (2013) 0.79
Sequence-dependent reactivity of linear DNA to chemical cleavage by Cu(II):thiol combinations including cysteine or glutathione. Biochem J (1993) 0.77
Inactivation of Escherichia coli by polychromatic simulated sunlight: evidence for and implications of a fenton mechanism involving iron, hydrogen peroxide, and superoxide. Appl Environ Microbiol (2013) 0.75
Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases. Arch Dermatol (1987) 5.88
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DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nat Immunol (2001) 4.00
The human XPG gene: gene architecture, alternative splicing and single nucleotide polymorphisms. Nucleic Acids Res (2001) 3.45
Acquired precursors of cutaneous malignant melanoma. The familial dysplastic nevus syndrome. N Engl J Med (1985) 2.54
Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells. Proc Natl Acad Sci U S A (1987) 2.50
DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum. Carcinogenesis (1984) 2.35
Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc Natl Acad Sci U S A (1975) 2.29
Cockayne syndrome and xeroderma pigmentosum. Neurology (2000) 2.24
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair. Nat Med (2001) 2.04
Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells. Proc Natl Acad Sci U S A (1986) 1.92
Five complementation groups in xeroderma pigmentosum. Mutat Res (1975) 1.91
Trichothiodystrophy: a systematic review of 112 published cases characterises a wide spectrum of clinical manifestations. J Med Genet (2008) 1.85
One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells. Proc Natl Acad Sci U S A (1985) 1.81
Familial cutaneous malignant melanoma: autosomal dominant trait possibly linked to the Rh locus. Proc Natl Acad Sci U S A (1983) 1.72
Ultraviolet hypermutability of a shuttle vector propagated in xeroderma pigmentosum variant cells. J Invest Dermatol (1993) 1.67
Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity. Proc Natl Acad Sci U S A (1987) 1.66
The dysplastic nevus syndrome: our definition. Am J Dermatopathol (1982) 1.63
Normal vitamin D levels can be maintained despite rigorous photoprotection: six years' experience with xeroderma pigmentosum. J Am Acad Dermatol (1997) 1.56
Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer. Mol Med Today (1999) 1.52
High risk of malignant melanoma in melanoma-prone families with dysplastic nevi. Ann Intern Med (1985) 1.51
Clearing of melanoma in situ with intralesional interferon alfa in a patient with xeroderma pigmentosum. Arch Dermatol (1994) 1.46
UV light-induced cyclobutane pyrimidine dimers are mutagenic in mammalian cells. Mol Cell Biol (1986) 1.41
Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene. Hum Mol Genet (2001) 1.33
Xeroderma pigmentosum--bridging a gap between clinic and laboratory. Photodermatol Photoimmunol Photomed (2001) 1.28
The effect of donor age on the processing of UV-damaged DNA by cultured human cells: reduced DNA repair capacity and increased DNA mutability. Mutat Res (1996) 1.26
The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts. Proc Natl Acad Sci U S A (2000) 1.25
An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study. Cancer Res (2001) 1.21
A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism. Carcinogenesis (2000) 1.21
DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells. J Invest Dermatol (1996) 1.20
Sequence specificity of aflatoxin B1-induced mutations in a plasmid replicated in xeroderma pigmentosum and DNA repair proficient human cells. Cancer Res (1992) 1.19
Adverse effects of trichothiodystrophy DNA repair and transcription gene disorder on human fetal development. Clin Genet (2009) 1.18
Precursor naevi in cutaneous malignant melanoma: a proposed nomenclature. Lancet (1980) 1.12
Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia. J Invest Dermatol (1998) 1.11
Metal-based formulations with high microbicidal activity. Appl Environ Microbiol (1992) 1.10
Xeroderma pigmentosum. Clin Dermatol (1986) 1.08
A stop codon in xeroderma pigmentosum group C families in Turkey and Italy: molecular genetic evidence for a common ancestor. J Invest Dermatol (2001) 1.08
Reduced repair of non-dimer photoproducts in a gene transfected into xeroderma pigmentosum cells. Photochem Photobiol (1986) 1.07
Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells. EMBO J (1989) 1.06
Expression of a transfected DNA repair gene (XPA) in xeroderma pigmentosum group A cells restores normal DNA repair and mutagenesis of UV-treated plasmids. Carcinogenesis (1995) 1.02
Clinical, cellular, and molecular features of an Israeli xeroderma pigmentosum family with a frameshift mutation in the XPC gene: sun protection prolongs life. J Invest Dermatol (2000) 1.02
Heritable genetic alterations in a xeroderma pigmentosum group G/Cockayne syndrome pedigree. Mutat Res (1997) 1.02
Quantification of expression of linked cloned genes in a simian virus 40-transformed xeroderma pigmentosum cell line. Mol Cell Biol (1985) 1.01
Dysplastic naevi and cutaneous melanoma risk. Lancet (1983) 0.99
Dysplastic nevi on the scalp of prepubertal children from melanoma-prone families. J Pediatr (1983) 0.98
Xeroderma pigmentosum: spinal cord astrocytoma with 9-year survival after radiation and isotretinoin therapy. J Cutan Med Surg (1998) 0.98
Detection of ataxia telangiectasia heterozygous cell lines by postirradiation cumulative labeling index: measurements with coded samples. Cancer Res (1987) 0.97
Repair of DNA in xeroderma pigmentosum conjunctiva. Arch Ophthalmol (1975) 0.95
Evidence for defective repair of cyclobutane pyrimidine dimers with normal repair of other DNA photoproducts in a transcriptionally active gene transfected into Cockayne syndrome cells. Mutat Res (1991) 0.95
Decreased thymidine incorporation in circulating leukocytes after treatment of psoriasis with psoralen and long-wave ultraviolet light. J Invest Dermatol (1977) 0.94
Adult-onset xeroderma pigmentosum neurological disease--observations in an autopsy case. Clin Neuropathol (2002) 0.93
Topical immunotherapy of basal cell carcinomas with dinitrochlorobenzene. Cancer Res (1973) 0.93
Risk of cutaneous melanoma in dysplastic nevus syndrome types A and B. N Engl J Med (1986) 0.93
The human DNA repair gene, ERCC2 (XPD), corrects ultraviolet hypersensitivity and ultraviolet hypermutability of a shuttle vector replicated in xeroderma pigmentosum group D cells. Cancer Res (1994) 0.93
Hereditary dysplastic nevus syndrome: lymphoid cell ultraviolet hypermutability in association with increased melanoma susceptibility. Cancer Res (1986) 0.92
Analysis of point mutations in an ultraviolet-irradiated shuttle vector plasmid propagated in cells from Japanese xeroderma pigmentosum patients in complementation groups A and F. Cancer Res (1991) 0.92
Hereditary melanoma and the dysplastic nevus syndrome: the risk of cancers other than melanoma. J Am Acad Dermatol (1987) 0.91
Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosum. J Clin Invest (1987) 0.91
Prolonged ultraviolet-induced thymidine incorporation into xeroderma pigmentosum lymphocytes: studies on its duration, amount, localization and relationship to hydroxyurea. Biochim Biophys Acta (1972) 0.91
An SV40-transformed xeroderma pigmentosum group D cell line: establishment, ultraviolet sensitivity, transfection efficiency and plasmid mutation induction. Mutat Res (1986) 0.90
Mutational hotspot variability in an ultraviolet-treated shuttle vector plasmid propagated in xeroderma pigmentosum and normal human lymphoblasts and fibroblasts. J Mol Biol (1990) 0.90
Ataxia-telangiectasis: a multisystem hereditary disease with immunodeficiency, impaired organ maturation, x-ray hypersensitivity, and a high incidence of neoplasia. Ann Intern Med (1983) 0.89
Ultraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal. Proc Natl Acad Sci U S A (1993) 0.89
Influence of ataxia telangiectasia gene dosage on bleomycin-induced chromosome breakage and inhibition of replication in human lymphoblastoid cell lines. Exp Cell Res (1982) 0.88
Survival of human lymphoblastoid cells after DNA damage measured by growth in microtiter wells. Mutat Res (1980) 0.88
Impaired ultraviolet-B-induced cytokine induction in xeroderma pigmentosum fibroblasts. J Invest Dermatol (2001) 0.87
Impaired interferon production and natural killer cell activation in patients with the skin cancer-prone disorder, xeroderma pigmentosum. J Clin Invest (1993) 0.86
Ultraviolet mutagenesis in human lymphocytes: the effect of cellular transformation. Exp Cell Res (1992) 0.86
Xeroderma pigmentosum long-term lymphoid lines with increased ultraviolet sensitivity. J Natl Cancer Inst (1974) 0.85
Ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum lymphoblastoid cells and fibroblasts. Mutat Res (1991) 0.85
Hypoglycinaemia and psychomotor delay in a child with xeroderma pigmentosum. J Inherit Metab Dis (1999) 0.83
Abnormal processing of transfected plasmid DNA in cells from patients with ataxia telangiectasia. Mutat Res (1992) 0.83
Abnormal rate and duration of ultraviolet-induced thymidine incorporation into lymphocytes from patients with Xeroderma pigmentosum and associated neurological complications. Mutat Res (1972) 0.82
Host cell reactivation by human cells of DNA expression vectors damaged by ultraviolet radiation or by acid-heat treatment. Carcinogenesis (1986) 0.81
Dysplastic nevus syndrome. Familial and sporadic precursors of cutaneous melanoma. Dermatol Clin (1985) 0.80
Carrier detection in xeroderma pigmentosum. J Clin Invest (1990) 0.80
Managing the dysplastic naevus syndrome. Lancet (1984) 0.80
Plasmid vectors for study of DNA repair and mutagenesis. Curr Probl Dermatol (1987) 0.80
Conformational differences in protein disulfide linkages between normal hair and hair from subjects with trichothiodystrophy: a quantitative analysis by Raman microspectroscopy. Biopolymers (2006) 0.80
In vitro assay of the effects of psoralens plus ultraviolet radiation on human lymphoid cells. J Natl Cancer Inst (1982) 0.79
Ultraviolet mutagenesis in a plasmid vector replicated in lymphoid cells from patient with the melanoma-prone disorder dysplastic nevus syndrome. Cancer Res (1989) 0.79
A potential laboratory test for dysplastic nevus syndrome: ultraviolet hypermutability of a shuttle vector plasmid. J Invest Dermatol (1994) 0.79
DNA repair in tumor cells from the variant form of xeroderma pigmentosum. J Invest Dermatol (1975) 0.79
Colony-forming ability of ultraviolet-irradiated xeroderma pigmentosum fibroblasts from different DNA repair complementation groups. Biochim Biophys Acta (1976) 0.78
Psoralen plus ultraviolet radiation-induced inhibition of DNA synthesis and viability in human lymphoid cells in vitro. Photochem Photobiol (1979) 0.78
Effects of 8-methoxypsoralen and ultraviolet radiation on human lymphoid cells in vitro. J Invest Dermatol (1981) 0.78
In-vivo assessment of DNA ligation efficiency and fidelity in cells from patients with Fanconi's anemia and other cancer-prone hereditary disorders. Toxicol Lett (1993) 0.78
Xeroderma pigmentosum. A prototype disease of environmental-genetic interaction. Arch Dermatol (1980) 0.78
N-methyl-N-nitrosourea-induced mutations in a shuttle plasmid replicated in human cells. Mol Carcinog (1990) 0.77
Hypermutability of UV-treated plasmids in dysplastic nevus/familial melanoma cell lines. Cancer Res (1997) 0.77
Complementing xeroderma pigmentosum fibroblasts restore biological activity to UV-damaged DNA. Mutat Res (1975) 0.77
Retinoid protection against x-ray-induced chromatid damage in human peripheral blood lymphocytes. J Clin Invest (1992) 0.77
Ultraviolet light selection assay to optimize oligonucleotide correction of mutations in endogenous xeroderma pigmentosum genes. Gene Ther (2004) 0.77
DNA crosslinking and cell survival in human lymphoid cells treated with 8-methoxypsoralen and long wavelength ultraviolet radiation. Mutat Res (1981) 0.76
Isotretinoin does prevent skin cancer. Arch Dermatol (1993) 0.75
Alterations in leukocyte aryl hydrocarbon hydroxylase activity associated with treatment and age in psoriasis patients and healthy individuals. Arch Dermatol Res (1984) 0.75
Dysplastic nevus syndrome and cancer risk--response. J Am Acad Dermatol (1987) 0.75
Effects of psoralens plus ultraviolet radiation on human lymphoid cells in vitro. Natl Cancer Inst Monogr (1984) 0.75
Effect of X-radiation on DNA and histone synthesis in ataxia telangiectasia and normal lymphoblastoid cells. Mutat Res (1983) 0.75
Xeroderma pigmentosum: a nursing perspective. Dermatol Nurs (1990) 0.75