Hapten-induced model of chronic inflammation and ulceration in the rat colon.

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Published in Gastroenterology on March 01, 1989

Authors

G P Morris1, P L Beck, M S Herridge, W T Depew, M R Szewczuk, J L Wallace

Author Affiliations

1: Department of Biology, Queen's University, Kingston, Ontario, Canada.

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Alendronate induces gastric injury and delays ulcer healing in rodents. Life Sci (1998) 0.91

Prostaglandin biosynthesis by gastric mucosa. I. Studies in rat. Clin Biochem (1984) 0.91

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Phosphodiesterase inhibitors prevent NSAID enteropathy independently of effects on TNF-alpha release. Am J Physiol (1999) 0.90

Upper gastrointestinal toxicity of alendronate. Am J Gastroenterol (2000) 0.90

Attenuation of epithelial injury in acute experimental colitis by immunomodulators. Eur J Pharmacol (1993) 0.89

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