PubRank

P J Sansonetti

Author PubWeight™ 274.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Involvement of a plasmid in the invasive ability of Shigella flexneri. Infect Immun 1982 13.55
2 Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis. Infect Immun 1986 9.35
3 Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Bull World Health Organ 1999 8.93
4 Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. J Bacteriol 1993 8.75
5 Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin. Proc Natl Acad Sci U S A 1989 7.00
6 Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri. Infect Immun 1985 6.74
7 Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri. Infect Immun 1983 6.43
8 Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence. Infect Immun 1981 6.40
9 Shigella flexneri induces apoptosis in infected macrophages. Nature 1992 6.26
10 Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation. Infect Immun 1987 5.92
11 Intracellular and cell-to-cell spread of Listeria monocytogenes involves interaction with F-actin in the enterocytelike cell line Caco-2. Infect Immun 1990 5.84
12 Characterization of virulence plasmids and plasmid-associated outer membrane proteins in Shigella flexneri, Shigella sonnei, and Escherichia coli. Infect Immun 1983 4.82
13 Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility. J Cell Biol 1999 4.20
14 MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins. Mol Microbiol 1993 4.17
15 IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole. EMBO J 1992 3.84
16 CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep 2001 3.55
17 Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole. Infect Immun 1992 3.43
18 IpaB mediates macrophage apoptosis induced by Shigella flexneri. Mol Microbiol 1994 3.27
19 Localization of plasmid loci necessary for the entry of Shigella flexneri into HeLa cells, and characterization of one locus encoding four immunogenic polypeptides. J Gen Microbiol 1987 3.05
20 MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins. J Bacteriol 1992 3.00
21 Molecular comparison of virulence plasmids in Shigella and enteroinvasive Escherichia coli. Ann Microbiol (Paris) 1983 2.93
22 Intracellular growth of Listeria monocytogenes as a prerequisite for in vivo induction of T cell-mediated immunity. J Immunol 1987 2.90
23 Identification of a chromosomal gene controlling temperature-regulated expression of Shigella virulence. Proc Natl Acad Sci U S A 1988 2.81
24 Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J Biol Chem 1998 2.75
25 Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement. J Bacteriol 1993 2.62
26 icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread. Mol Microbiol 1992 2.57
27 Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis. J Exp Med 1994 2.53
28 Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structures. Mol Microbiol 1995 2.52
29 Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. J Clin Invest 1994 2.47
30 Nucleotide sequence of the invasion plasmid antigen B and C genes (ipaB and ipaC) of Shigella flexneri. Microb Pathog 1988 2.43
31 Plasmid-mediated invasiveness of "Shigella-like" Escherichia coli. Ann Microbiol (Paris) 1982 2.38
32 A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii. J Cell Sci 1999 2.32
33 Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor. Infect Immun 1989 2.30
34 SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion. Mol Microbiol 1995 2.27
35 DNA hybridization technique to detect Shigella species and enteroinvasive escherichia coli. J Clin Microbiol 1984 2.24
36 IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells. EMBO J 1999 2.20
37 Plasmid-mediated early killing of eucaryotic cells by Shigella flexneri as studied by infection of J774 macrophages. Infect Immun 1987 2.17
38 Secretion of Ipa proteins by Shigella flexneri: inducer molecules and kinetics of activation. Infect Immun 1997 2.15
39 Contribution of superoxide dismutase and catalase activities to Shigella flexneri pathogenesis. Infect Immun 1990 2.14
40 Correlation of the virulence of Klebsiella pneumoniae K1 and K2 with the presence of a plasmid encoding aerobactin. Infect Immun 1986 2.12
41 Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells. J Cell Biol 1995 2.06
42 Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J Immunol 2000 2.05
43 A nonvirulent mutant of Listeria monocytogenes does not move intracellularly but still induces polymerization of actin. Infect Immun 1990 2.00
44 The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri. J Bacteriol 1990 1.96
45 Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri. J Clin Invest 1994 1.95
46 Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway. EMBO J 1995 1.95
47 Genetic determinants of Shigella pathogenicity. Annu Rev Microbiol 1988 1.94
48 Role of Shiga toxin in the pathogenesis of bacillary dysentery, studied by using a Tox- mutant of Shigella dysenteriae 1. Infect Immun 1988 1.94
49 Identification of a clone of Escherichia coli O103:H2 as a potential agent of hemolytic-uremic syndrome in France. J Clin Microbiol 1993 1.94
50 SopA, the outer membrane protease responsible for polar localization of IcsA in Shigella flexneri. Mol Microbiol 1997 1.93
51 Invasive enteric pathogens. Rev Infect Dis 1983 1.91
52 Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin. EMBO J 1997 1.90
53 The unrelated surface proteins ActA of Listeria monocytogenes and IcsA of Shigella flexneri are sufficient to confer actin-based motility on Listeria innocua and Escherichia coli respectively. Mol Microbiol 1995 1.87
54 Mechanism of Shigella entry into epithelial cells. Curr Opin Microbiol 1999 1.87
55 Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri. Infect Immun 1992 1.86
56 Characterization of the Shigella flexneri ipgD and ipgF genes, which are located in the proximal part of the mxi locus. Infect Immun 1993 1.84
57 In vivo apoptosis in Shigella flexneri infections. Infect Immun 1996 1.81
58 Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death? Trends Microbiol 1997 1.81
59 Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602. Infect Immun 1999 1.80
60 Positive control of colanic acid synthesis in Escherichia coli by rmpA and rmpB, two virulence-plasmid genes of Klebsiella pneumoniae. Mol Microbiol 1989 1.69
61 Bacterial entry into epithelial cells: the paradigm of Shigella. Trends Microbiol 1996 1.67
62 Stress fiber-based movement of Shigella flexneri within cells. Infect Immun 1991 1.63
63 Unipolar reorganization of F-actin layer at bacterial division and bundling of actin filaments by plastin correlate with movement of Shigella flexneri within HeLa cells. Infect Immun 1992 1.63
64 Plasmid-mediated contact haemolytic activity in Shigella species: correlation with penetration into HeLa cells. Ann Inst Pasteur Microbiol 1988 1.60
65 Invasion and the pathogenesis of Shigella infections. Curr Top Microbiol Immunol 1996 1.60
66 Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility. J Cell Sci 1999 1.53
67 Evaluation with an iuc::Tn10 mutant of the role of aerobactin production in the virulence of Shigella flexneri. Infect Immun 1987 1.48
68 OmpC is involved in invasion of epithelial cells by Shigella flexneri. Infect Immun 1993 1.47
69 Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins. EMBO J 1998 1.46
70 Shigella subversion of the cellular cytoskeleton: a strategy for epithelial colonization. Infect Immun 1993 1.45
71 Movement along actin filaments of the perijunctional area and de novo polymerization of cellular actin are required for Shigella flexneri colonization of epithelial Caco-2 cell monolayers. Infect Immun 1992 1.43
72 Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization. EMBO J 1999 1.35
73 Bacterial signals and cell responses during Shigella entry into epithelial cells. Cell Microbiol 2000 1.29
74 Phosphorylation of IcsA by cAMP-dependent protein kinase and its effect on intracellular spread of Shigella flexneri. Mol Microbiol 1992 1.29
75 Regulation of surface presentation of IcsA, a Shigella protein essential to intracellular movement and spread, is growth phase dependent. Infect Immun 1994 1.25
76 Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent. Infect Immun 1997 1.24
77 IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis. J Immunol 1999 1.24
78 Innate immune responses of epithelial cells following infection with bacterial pathogens. Curr Opin Immunol 2001 1.21
79 Presence and expression of aerobactin genes in virulent avian strains of Escherichia coli. Infect Immun 1987 1.19
80 The secreted IpaB and IpaC invasins and their cytoplasmic chaperone IpgC are required for intercellular dissemination of Shigella flexneri. Cell Microbiol 1999 1.19
81 MxiG, a membrane protein required for secretion of Shigella spp. Ipa invasins: involvement in entry into epithelial cells and in intercellular dissemination. Mol Microbiol 1995 1.18
82 SepA, the 110 kDa protein secreted by Shigella flexneri: two-domain structure and proteolytic activity. Microbiology 1998 1.15
83 IpgD, a protein secreted by the type III secretion machinery of Shigella flexneri, is chaperoned by IpgE and implicated in entry focus formation. Mol Microbiol 2000 1.14
84 Chloroquine-resistant Plasmodium falciparum in Cameroon. Lancet 1985 1.13
85 Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells. J Cell Biol 1998 1.12
86 Internalization of Shigella flexneri into HeLa cells occurs without an increase in cytosolic Ca2+ concentration. Infect Immun 1989 1.10
87 Molecular mechanisms of entry, intracellular multiplication and killing of host cells by shigellae. Curr Top Microbiol Immunol 1988 1.09
88 Slaying the Hydra all at once or head by head? Nat Med 1998 1.08
89 Molecular and cellular mechanisms of tissue invasion by Shigella flexneri. Ann N Y Acad Sci 1994 1.07
90 The pathogenesis of Shigella flexneri infection: lessons from in vitro and in vivo studies. Philos Trans R Soc Lond B Biol Sci 2000 1.06
91 Purification of IpaC, a protein involved in entry of Shigella flexneri into epithelial cells and characterization of its interaction with lipid membranes. FEBS Lett 1997 1.05
92 Production of IFN-gamma and IL-10 to Shigella invasins by mononuclear cells from volunteers orally inoculated with a Shiga toxin-deleted Shigella dysenteriae type 1 strain. J Immunol 2000 1.04
93 Induction of necrosis in human neutrophils by Shigella flexneri requires type III secretion, IpaB and IpaC invasins, and actin polymerization. Infect Immun 2000 1.04
94 Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement. Infect Agents Dis 1993 1.04
95 Evidence for clathrin mobilization during directed phagocytosis of Shigella flexneri by HEp2 cells. Microb Pathog 1989 1.04
96 Trafficking of Shigella lipopolysaccharide in polarized intestinal epithelial cells. J Cell Biol 1999 1.02
97 A newborn mouse model for the study of intestinal pathogenesis of shigellosis. Cell Microbiol 2003 1.00
98 Lack of cleavage of IcsA in Shigella flexneri causes aberrant movement and allows demonstration of a cross-reactive eukaryotic protein. Infect Immun 1996 1.00
99 Shigellosis: innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine development. Crit Rev Immunol 2003 1.00
100 Invasion of epithelial cells by bacterial pathogens the paradigm of Shigella. Subcell Biochem 2000 1.00
101 Construction and evaluation of live attenuated vaccine strains of Shigella flexneri and Shigella dysenteriae 1. Res Microbiol 1991 0.96
102 Protection against invasion of the mouse pulmonary epithelium by a monoclonal IgA directed against Shigella flexneri lipopolysaccharide. Ann N Y Acad Sci 1994 0.95
103 Detection of enteric pathotypes of Escherichia coli by hybridization using six DNA probes. Ann Inst Pasteur Microbiol 1988 0.95
104 Predominance of serotype-specific mucosal antibody response in Shigella flexneri-infected humans living in an area of endemicity. Infect Immun 2001 0.94
105 Induction of anti-carbohydrate antibodies by phage library-selected peptide mimics. Eur J Immunol 1997 0.92
106 Shigella flexneri: isolation of noninvasive mutants of gram-negative pathogens. Methods Enzymol 1994 0.92
107 Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes. Infect Immun 1997 0.90
108 Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental Shigellosis. Infect Immun 1999 0.89
109 A function for AAMP in Nod2-mediated NF-kappaB activation. Mol Immunol 2009 0.87
110 Diversion of cytoskeletal processes by Shigella during invasion of epithelial cells. Microbes Infect 2000 0.87
111 Shigella flexneri transformants expressing type 1 (mannose-specific) fimbriae bind to, activate, and are killed by phagocytic cells. Infect Immun 1993 0.87
112 Macrophage apoptosis in microbial infections. Parasitology 1997 0.86
113 Induction of adherence and degranulation of polymorphonuclear leukocytes: a new expression of the invasive phenotype of Shigella flexneri. Infect Immun 1996 0.84
114 Microbial-host interactions at mucosal sites. Host response to pathogenic bacteria at mucosal sites. Curr Top Microbiol Immunol 1999 0.83
115 Immunogenicity of IpaC-hybrid proteins expressed in the Shigella flexneri 2a vaccine candidate SC602. Infect Immun 1998 0.82
116 Rho GTP-binding proteins as targets for microbial pathogens. Prog Mol Subcell Biol 1999 0.81
117 The nadB gene of Salmonella typhimurium complements the nicotinic acid auxotrophy of Shigella flexneri. Mol Gen Genet 1996 0.80
118 Identification of a clone of Escherichia coli O103:H2 as potential agent of hemolytic-uremic syndrome in France. J Clin Microbiol 1994 0.80
119 A model of interaction between Entamoeba histolytica and Shigella flexneri. Res Microbiol 1992 0.79
120 Nucleotide sequence of rmpB, a Klebsiella pneumoniae gene that positively controls, colanic biosynthesis in Escherichia coli. Res Microbiol 1991 0.79
121 Interaction between Entamoeba histolytica and intestinal epithelial cells involves a CD44 cross-reactive protein expressed on the parasite surface. Infect Immun 1997 0.79
122 Parameters underlying successful protection with live attenuated mutants in experimental shigellosis. Infect Immun 2001 0.79
123 The ipaB gene of Shigella flexneri and macrophage-programmed cell death. Infect Agents Dis 1993 0.78
124 Plasmid-mediated intracellular multiplication of Shigella flexneri. Ann Inst Pasteur Microbiol 1988 0.77
125 Elimination of a virulence plasmid from Shigella sonnei and Escherichia coli by antibiotics. Ann Inst Pasteur Microbiol 1988 0.77
126 [Molecular and cellular mechanisms of invasion of the intestinal barrier by Shigella flexneri]. Pathol Biol (Paris) 1993 0.75
127 [Early involvement of the central nervous system in HIV infection: screening by MRI (a 5-year follow-up)]. C R Acad Sci III 1993 0.75
128 [Chemical resistance of Plasmodium falciparum in Africa. Current situation, implications for chemoprophylaxis]. Biomed Pharmacother 1987 0.75
129 [Plasmodium falciparum malaria attacks with low or negative parasitemia on returning from areas of endemic resistance to 4-aminoquinolines]. Presse Med 1986 0.75
130 [Dysentery caused by Shigella and enteroinvasive Escherichia coli. Diagnosis by DNA/DNA hybridization]. Arch Inst Pasteur Madagascar 1988 0.75
131 [Cerebral MRI in the study of prognostic factors in AIDS. Hypotheses from tests on 15 patients]. J Radiol 1988 0.75
132 [Tomorrow's vaccines]. Presse Med 1987 0.75
133 [Subacute septicemia caused by Meningococcus of serogroup Y and acquired deficiency of complement C3 fraction]. Ann Med Interne (Paris) 1986 0.75
134 [Antibiotic therapy of purulent meningitis]. Ann Med Interne (Paris) 1986 0.75
135 [The role of 4-quinolones and antibiotics in the elimination of virulence plasmids of Enterobacteriaceae]. Pathol Biol (Paris) 1987 0.75
136 [Magnetic resonance imaging: early detection of involvement of the central nervous system in acquired immunodeficiency syndrome]. C R Acad Sci III 1988 0.75