Published in J Biol Chem on January 15, 1986
The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. J Clin Invest (1996) 1.31
Thrombin, unlike vasopressin, appears to stimulate two distinct guanine nucleotide regulatory proteins in human platelets. Biochem J (1986) 1.13
Thrombin exerts a dual effect on stimulated adenylate cyclase in hamster fibroblasts, an inhibition via a GTP-binding protein and a potentiation via activation of protein kinase C. Biochem J (1988) 1.12
The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation. J Clin Invest (1993) 1.00
Thrombin-induced phosphoinositide hydrolysis in platelets. Receptor occupancy and desensitization. Biochem J (1987) 0.93
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets. Biochem J (1987) 0.90
Alcohol-induced stimulation of phospholipase C in human platelets requires G-protein activation. Biochem J (1988) 0.88
Effects of separate proteolytic and high-affinity binding activities of human thrombin on rapid platelet activation. A quenched-flow study. Biochem J (1989) 0.82
Multiphasic generation of diacylglycerol in thrombin-activated human platelets. Biochem J (1992) 0.81
Different pathways for control of Na+/H+ exchange via activation of the thrombin receptor. Biochem J (1994) 0.80
Regulation of platelet glycoprotein IIb/IIIa (integrin alpha IIB beta 3) function via the thrombin receptor. Biochem J (1995) 0.78
G protein activation and mediator release from human neutrophils and platelets after stimulation with sodium fluoride and receptor-mediated stimuli. Immunology (1991) 0.76
Thrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human platelets. Biochem J (1991) 0.75
Interrelations of platelet aggregation and secretion. J Clin Invest (1977) 1.93
Expression of the firefly luciferase gene in vaccinia virus: a highly sensitive gene marker to follow virus dissemination in tissues of infected animals. Proc Natl Acad Sci U S A (1988) 1.78
Measurement of soluble transferrin receptor in serum of healthy adults. Clin Chem (1998) 1.60
Platelet secretion induced by divalent cation ionophores. Nature (1974) 1.60
Equilibrium binding of thrombin to platelets. Biochemistry (1976) 1.48
The action of calcium-dependent protease on platelet surface glycoproteins. Arch Biochem Biophys (1983) 1.44
Inhibition of platelet secretion by an antagonist of intracellular calcium. Biochem Biophys Res Commun (1976) 1.37
Kinetics of the thrombin-induced release of adenosine triphosphate by platelets. Comparison with release of calcium. Biochemistry (1973) 1.29
Kinetics of the thrombin-induced release of calcium (II) by platelets. Biochemistry (1973) 1.27
Protein disulfide isomerase activity is released by activated platelets. Blood (1992) 1.21
Characterization of protein disulphide isomerase released from activated platelets. Br J Haematol (1995) 1.16
Evidence that calcium regulates platelet function. Thromb Haemost (1978) 1.14
Delayed degeneration of dystrophic and normal muscle cell cultures treated with pepstatin, leupeptin, and antipain. Exp Neurol (1976) 1.08
Platelet stimulation by thrombin and other proteases. Biochemistry (1975) 1.08
Inhibition of calpain in intact platelets by the thiol protease inhibitor E-64d. Biochem Biophys Res Commun (1989) 1.07
Muscular dystrophy: inhibition of degeneration in vivo with protease inhibitors. Science (1978) 1.05
Platelet thrombin receptors. Binding of alpha-thrombin is coupled to signal generation by a chymotrypsin-sensitive mechanism. J Biol Chem (1980) 1.01
Dissociation of thrombin from platelets by hirudin. Evidence for receptor processing. J Biol Chem (1979) 0.97
Stimulus-secretion coupling in platelets. Effects of drugs on secretion on adenosine 5'-triphosphate. Biochemistry (1975) 0.95
Thrombin-induced phosphoinositide hydrolysis in platelets. Receptor occupancy and desensitization. Biochem J (1987) 0.93
Reactivity of individual tyrosyl residues of horse heart ferricytochrome c toward iodination. Biochemistry (1970) 0.93
The effects of lithium on platelet phosphoinositide metabolism. Biochem J (1986) 0.91
Characteristics of the synergistic actions of platelet agonists. Blood (1981) 0.91
Letter to the editors-in-chief: Absence of a requirement for extracellular calcium for secretion from platelets. Thromb Res (1975) 0.90
Free thiols of platelet thrombospondin. Evidence for disulfide isomerization. J Biol Chem (1990) 0.89
Reassessment of the evidence for the role of secreted ADP in biphasic platelet aggregation. Mechanism of inhibition by creatine phosphate plus creatine phosphokinase. J Lab Clin Med (1980) 0.89
Quantitative evaluation of the loss of human platelet dense bodies following stimulation by thrombin or A23187. J Physiol (1977) 0.89
Thrombin adsorption to surfaces and prevention with polyethylene glycol 6,000. Thromb Res (1976) 0.88
Thiol-disulfide isomerization in thrombospondin: effects of conformation and protein disulfide isomerase. Blood (1997) 0.87
A second form of actin: platelet microfilaments depolymerized by ATP and divalent cations. Arch Biochem Biophys (1975) 0.87
In vivo effect of protease inhibitors in denervation atrophy. Exp Neurol (1979) 0.86
Ester and amide derivatives of E64c as inhibitors of platelet calpains. J Med Chem (1992) 0.85
Thiol-disulfide exchange by thrombospondin: evidence for a thiol and a disulfide bond protected by calcium. Arch Biochem Biophys (1986) 0.85
Prostaglandin endoperoxides and thromboxane A2 can induce platelet aggregation in the absence of secretion. Nature (1977) 0.85
Relationship between myosin structure and muscle degeneration. Ann N Y Acad Sci (1979) 0.85
Effects of deoxyglucose on platelet metabolism. Biochim Biophys Acta (1971) 0.84
Regulation of platelet phosphorylase. Biochim Biophys Acta (1975) 0.84
Proteolysis of myosin during platelet storage. J Clin Invest (1974) 0.84
Involvement of a tryptophan residue in the binding site of Escherichia coli galactose-binding protein. Biochemistry (1974) 0.83
Characterization of the thrombin-induced desensitization of platelet activation by thrombin. Thromb Res (1983) 0.83
Levels of intermediates and cofactors of the glycolytic pathway and the citric acid cycle in rat platelets. Biochim Biophys Acta (1969) 0.83
Rabbit muscle phosphorylase phosphatase. 2. Kinetic properties and behavior in glycogen particles. Biochemistry (1977) 0.82
Quantitative adsorption of platelet glycoprotein G (thrombin-sensitive protein, thrombospondin) to barium citrate. Biochem J (1984) 0.82
Formation of a stable complex of thrombin and the secreted platelet protein glycoprotein G (thrombin-sensitive protein, thrombospondin) by thiol-disulfide exchange. Biochemistry (1984) 0.82
Control of energy metabolism in platelets. A comparison of aerobic and anaerobic metabolism in washed rat platelets. Biochim Biophys Acta (1970) 0.82
Correlation of thrombin-induced glycoprotein V hydrolysis and platelet activation. J Biol Chem (1983) 0.81
Reactions of thrombin-serpin complexes with thrombospondin. Arch Biochem Biophys (1992) 0.80
Kinetics of the formation of thrombin-thrombospondin complexes: involvement of a 77-kDa intermediate. Arch Biochem Biophys (1988) 0.80
The structure of hemopeptide 1-65 from cytochrome c. Arch Biochem Biophys (1972) 0.79
Reduction of a disulfide bond of thrombospondin in the supernatant solution of activated platelets. Arch Biochem Biophys (1991) 0.79
Hypothetical models for the thrombin-platelet interaction. Ann N Y Acad Sci (1981) 0.79
Localization of a thrombin-sensitive calcium pool in platelets. J Histochem Cytochem (1975) 0.79
Inhibition by digitonin of bovine heart muscle DPNH-cytochrome c reductase and its specific reversal by the tocopherols. Biochem Biophys Res Commun (1964) 0.78
Binding of thrombin to human platelet plasma membranes. Biochim Biophys Acta (1978) 0.78
Stimulus-response coupling in the thrombin-platelet interaction. Ciba Found Symp (1975) 0.77
Control of energy metabolism in platelets. The effects of thrombin and cyanide on glycolysis. Biochim Biophys Acta (1972) 0.77
Effects of digitonin and tocopherol on bovine heart muscle reduced diphosphopyridine nucleotide- and succinate-cytochrome c reductase and cytochrome c oxidase. J Biol Chem (1966) 0.77
Structural location of the tyrosyl and tryptophanyl residues of tuna heart cytochrome c. Biochemistry (1970) 0.77
Differential effect of Serratia protease on platelet surface glycoproteins Ib and V. Blood (1985) 0.75
Characteristics of a thrombin inhibitor secreted by activated platelets. Arch Biochem Biophys (1990) 0.75
Succinate potentiates the action of platelet agonists. Thromb Res (1984) 0.75
Arachidonate is an antagonist of platelet activation by the endoperoxide analog U46619. Biochim Biophys Acta (1982) 0.75
Rabbit muscle phosphorylase phosphatase. 1. Purification and chemical properties. Biochemistry (1977) 0.75
Platelet receptors for thrombin. Adv Exp Med Biol (1985) 0.75
Light meromyosin paracrystals from normal and dystrophic avian muscle. Exp Neurol (1977) 0.75
The reaction of thrombin with platelet-derived nexin requires a secondary recognition site in addition to the catalytic site. Biochem Biophys Res Commun (1991) 0.75
Allosteric regulation of platelet actomyosin. Biochem Biophys Res Commun (1973) 0.75
Thrombin-induced release of glycolytic intermediates from rat platelets. Biochim Biophys Acta (1970) 0.75
Photoaffinity labeling of platelet thrombin-binding proteins. Biochim Biophys Acta (1984) 0.75
Analysis of the fate of platelet-bound thrombin. Arch Biochem Biophys (1985) 0.75
Role of Ca2+ in the allosteric regulation of platelet actomyosin. Biochem Biophys Res Commun (1974) 0.75
Complexes of thrombin with secreted platelet proteins. Biochem Biophys Res Commun (1988) 0.75
Thrombin-platelet interactions: an assessment of the roles of saturable and nonsaturable binding in platelet activation. Arch Biochem Biophys (1983) 0.75