Published in Virus Res on December 01, 1985
Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J (1994) 3.26
Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs. J Virol (1995) 2.16
The influenza A virus PB2 polymerase subunit is required for the replication of viral RNA. J Virol (1997) 1.71
The N-terminal half of the influenza virus NS1 protein is sufficient for nuclear retention of mRNA and enhancement of viral mRNA translation. Nucleic Acids Res (1997) 1.48
Analysis of genetic variability and mapping of point mutations in influenza virus by the RNase A mismatch cleavage method. Proc Natl Acad Sci U S A (1988) 1.21
The 5' ends of Thogoto virus (Orthomyxoviridae) mRNAs are homogeneous in both length and sequence. J Virol (1996) 1.01
Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes. EMBO J (1986) 0.92
Permanent cell lines established from ts-COS cells that regulate by temperature the amplification and expression of cloned genes. Nucleic Acids Res (1987) 0.81
Nucleotide sequence heterogeneity of an RNA phage population. Cell (1978) 5.55
Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet. Proc Natl Acad Sci U S A (1992) 4.22
Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action. Microbiol Mol Biol Rev (2006) 4.13
The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review. Gene (1985) 3.42
Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J (1994) 3.26
Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis. J Virol (1990) 3.11
Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture. Virology (1983) 3.04
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell (2000) 2.97
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG. Nature (1999) 2.87
The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate. Gene (1976) 2.77
Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J Virol (1995) 2.68
Exponential increases of RNA virus fitness during large population transmissions. Proc Natl Acad Sci U S A (1995) 2.60
Genetic bottlenecks and population passages cause profound fitness differences in RNA viruses. J Virol (1993) 2.55
Influenza virus matrix protein is the major driving force in virus budding. J Virol (2000) 2.49
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol (2000) 2.48
Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance. Nucleic Acids Res (1986) 2.45
Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth-disease virus. Gene (1980) 2.44
Genetic lesions associated with Muller's ratchet in an RNA virus. J Mol Biol (1996) 2.41
Identification of new polypeptide species (48-55K) immunoprecipitable by antiserum to purified large T antigen and present in SV40-infected and -transformed cells. Virology (1979) 2.38
Lack of evolutionary stasis during alternating replication of an arbovirus in insect and mammalian cells. J Mol Biol (1999) 2.28
Virus mutation frequencies can be greatly underestimated by monoclonal antibody neutralization of virions. J Virol (1989) 2.27
Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity. J Virol (2000) 2.26
Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase. Gene (1992) 2.20
Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness. J Virol (1995) 2.18
Marked differences in the antigenic structure of human respiratory syncytial virus F and G glycoproteins. J Virol (1989) 2.17
Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs. J Virol (1995) 2.16
Evolution of cell recognition by viruses. Science (2001) 2.14
Subclonal components of consensus fitness in an RNA virus clone. J Virol (1994) 2.09
RNA virus quasispecies: significance for viral disease and epidemiology. Infect Agents Dis (1994) 2.08
KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. Oncogene (2006) 2.07
Vertebral endplate changes are not associated with chronic low back pain among Southern European subjects: a case control study. AJNR Am J Neuroradiol (2012) 2.06
The two species of the foot-and-mouth disease virus leader protein, expressed individually, exhibit the same activities. Virology (1993) 2.05
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion. Proc Natl Acad Sci U S A (2001) 2.04
Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker. Gene (1988) 2.03
The mammalian staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport. J Neurosci (1999) 2.03
Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit. J Gen Virol (1994) 2.03
Conserved regulation of proximodistal limb axis development by Meis1/Hth. Nature (1999) 2.03
Individual expression of influenza virus PA protein induces degradation of coexpressed proteins. J Virol (1995) 2.02
[Factors associated with the accumulation of abdominal fat estimated with anthropometric indexes]. Med Clin (Barc) (2000) 2.02
[Nodular subependymal heterotopia and epilepsy]. Neurologia (1995) 2.02
Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet. J Mol Biol (1999) 2.00
Distinct regions of influenza virus PB1 polymerase subunit recognize vRNA and cRNA templates. EMBO J (1999) 2.00
Rescue of a synthetic chloramphenicol acetyltransferase RNA into influenza virus-like particles obtained from recombinant plasmids. J Virol (1996) 1.98
PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators. J Virol (2001) 1.98
Genetic variability of Hong Kong (H3N2) influenza viruses: spontaneous mutations and their location in the viral genome. Gene (1980) 1.95
Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro. J Virol (1994) 1.93
Rapid selection of genetic and antigenic variants of foot-and-mouth disease virus during persistence in cattle. J Virol (1988) 1.92
Coevolution of cells and viruses in a persistent infection of foot-and-mouth disease virus in cell culture. J Virol (1988) 1.90
Efficient formation of influenza virus-like particles: dependence on the expression levels of viral proteins. J Gen Virol (1999) 1.89
Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies. J Virol (1991) 1.89
Identification of two separate domains in the influenza virus PB1 protein involved in the interaction with the PB2 and PA subunits: a model for the viral RNA polymerase structure. Nucleic Acids Res (1996) 1.89
Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies. Virology (2000) 1.87
Efficient virus extinction by combinations of a mutagen and antiviral inhibitors. J Virol (2001) 1.86
Ultrastructural and functional analyses of recombinant influenza virus ribonucleoproteins suggest dimerization of nucleoprotein during virus amplification. J Virol (2000) 1.86
Drastic fitness loss in human immunodeficiency virus type 1 upon serial bottleneck events. J Virol (1999) 1.85
Establishment of cell lines persistently infected with foot-and-mouth disease virus. Virology (1985) 1.84
Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells. J Virol (1995) 1.84
The red queen reigns in the kingdom of RNA viruses. Proc Natl Acad Sci U S A (1994) 1.83
Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system. J Gen Virol (1994) 1.83
Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas. Gastroenterology (2010) 1.83
The structure and antigenicity of a type C foot-and-mouth disease virus. Structure (1994) 1.82
Host nuclear proteins expressed in simian virus 40-transformed and -infected cells. Proc Natl Acad Sci U S A (1980) 1.82
The amino-terminal one-third of the influenza virus PA protein is responsible for the induction of proteolysis. J Virol (1996) 1.79
Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo. J Gen Virol (1997) 1.79
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep (2001) 1.76
Identification of an RNA binding region within the N-terminal third of the influenza A virus nucleoprotein. J Virol (1995) 1.76
RNA virus evolution and the control of viral disease. Prog Drug Res (1989) 1.74
Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses. J Gen Virol (1993) 1.74
A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum. Mol Cell Biol (1999) 1.74
In vitro site-directed mutagenesis: generation and properties of an infectious extracistronic mutant of bacteriophage Qbeta. Gene (1976) 1.72
Evolution of the capsid protein genes of foot-and-mouth disease virus: antigenic variation without accumulation of amino acid substitutions over six decades. J Virol (1992) 1.72
The influenza A virus PB2 polymerase subunit is required for the replication of viral RNA. J Virol (1997) 1.71
Implications of a quasispecies genome structure: effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus. Proc Natl Acad Sci U S A (1989) 1.71
Memory in viral quasispecies. J Virol (2000) 1.70
Loss of conserved cysteine residues in the attachment (G) glycoprotein of two human respiratory syncytial virus escape mutants that contain multiple A-G substitutions (hypermutations). Virology (1994) 1.69
The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis. J Virol (2000) 1.69
CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer. Oncogene (2010) 1.65
Evolution of the nucleotide sequence of influenza virus RNA segment 7 during drift of the H3N2 subtype. Gene (1983) 1.64
Heterogeneity of the mutation rates of influenza A viruses: isolation of mutator mutants. J Virol (1992) 1.61
Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity. Proc Natl Acad Sci U S A (2002) 1.60
Exponential fitness gains of RNA virus populations are limited by bottleneck effects. J Virol (1999) 1.60
Nuclear transport of influenza virus polymerase PA protein. Virus Res (1992) 1.59
Frame shift mutations as a novel mechanism for the generation of neutralization resistant mutants of human respiratory syncytial virus. EMBO J (1990) 1.59